Published in Pharmacol Ther on January 26, 2008
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The function and three-dimensional structure of a thromboxane A2/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite. PLoS Biol (2010) 1.09
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Adipocytokines in atherothrombosis: focus on platelets and vascular smooth muscle cells. Mediators Inflamm (2010) 0.90
Thromboxane-induced contractile response of human coronary arterioles is diminished after cardioplegic arrest. Ann Thorac Surg (2011) 0.88
Reduced methylation of the thromboxane synthase gene is correlated with its increased vascular expression in preeclampsia. Hypertension (2012) 0.86
Thromboxane and the thromboxane receptor in cardiovascular disease. Clin Lipidol (2010) 0.86
Global transcriptional response of macrophage-like THP-1 cells to Shiga toxin type 1. Infect Immun (2010) 0.86
Platelet function and Isoprostane biology. Should isoprostanes be the newest member of the orphan-ligand family? J Biomed Sci (2010) 0.85
Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages. Am J Physiol Lung Cell Mol Physiol (2015) 0.85
Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer. Mol Cancer (2014) 0.84
18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer. PLoS One (2014) 0.83
Cyclooxygenase-2 in newborn hyperoxic lung injury. Free Radic Biol Med (2013) 0.83
Thromboxane receptor signaling is required for fibronectin-induced matrix metalloproteinase 9 production by human and murine macrophages and is attenuated by the Arhgef1 molecule. J Biol Chem (2011) 0.83
Constrictor prostanoids and uridine adenosine tetraphosphate: vascular mediators and therapeutic targets in hypertension and diabetes. Br J Pharmacol (2015) 0.82
Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries. Am J Physiol Heart Circ Physiol (2012) 0.82
Pathophysiology of isoprostanes in the cardiovascular system: implications of isoprostane-mediated thromboxane A2 receptor activation. Br J Pharmacol (2014) 0.82
Endothelial dysfunction in cirrhosis: Role of inflammation and oxidative stress. World J Hepatol (2015) 0.82
Arachidonic acid metabolites follow the preferential course of cyclooxygenase pathway for the basal tone in the internal anal sphincter. Am J Physiol Gastrointest Liver Physiol (2009) 0.81
Pregnancy reduces RhoA/Rho kinase and protein kinase C signaling pathways downstream of thromboxane receptor activation in the rat uterine artery. Am J Physiol Heart Circ Physiol (2012) 0.81
Nature of extracellular signal that triggers RhoA/ROCK activation for the basal internal anal sphincter tone in humans. Am J Physiol Gastrointest Liver Physiol (2015) 0.80
Inhibitors of the 5-lipoxygenase pathway activate pannexin1 channels in macrophages via the thromboxane receptor. Am J Physiol Cell Physiol (2014) 0.80
Biased suppression of TP homodimerization and signaling through disruption of a TM GxxxGxxxL helical interaction motif. J Lipid Res (2013) 0.80
Thromboxane A2 modulates cisplatin-induced apoptosis through a Siva1-dependent mechanism. Cell Death Differ (2012) 0.80
2-arachidonyl glycerol activates platelets via conversion to arachidonic acid and not by direct activation of cannabinoid receptors. Br J Clin Pharmacol (2010) 0.79
Aging-shifted prostaglandin profile in endothelium as a factor in cardiovascular disorders. J Aging Res (2012) 0.79
Impaired contractile response of human peripheral arterioles to thromboxane A-2 after cardiopulmonary bypass. Surgery (2011) 0.79
RNA-Seq analysis reveals new evidence for inflammation-related changes in aged kidney. Oncotarget (2016) 0.78
Can active components of licorice, glycyrrhizin and glycyrrhetinic acid, lick rheumatoid arthritis? Oncotarget (2016) 0.78
Thromboxane A2 exerts promoting effects on cell proliferation through mediating cyclooxygenase-2 signal in lung adenocarcinoma cells. J Cancer Res Clin Oncol (2014) 0.78
Thromboxane A2 receptor antagonist SQ29548 reduces ischemic stroke-induced microglia/macrophages activation and enrichment, and ameliorates brain injury. Sci Rep (2016) 0.78
Superactive mutants of thromboxane prostanoid receptor: functional and computational analysis of an active form alternative to constitutively active mutants. Cell Mol Life Sci (2010) 0.77
Evaluation of antiaggregatory activity of flavonoid aglycone series. Nutr J (2011) 0.77
Heterodimerization with the prostacyclin receptor triggers thromboxane receptor relocation to lipid rafts. Arterioscler Thromb Vasc Biol (2012) 0.77
Inflammatory Eicosanoids Increase Amyloid Precursor Protein Expression via Activation of Multiple Neuronal Receptors. Sci Rep (2015) 0.77
Thromboxane A2 Receptor Stimulation Enhances Microglial Interleukin-1β and NO Biosynthesis Mediated by the Activation of ERK Pathway. Front Aging Neurosci (2016) 0.77
Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2)-receptor antagonists. ACS Med Chem Lett (2014) 0.76
Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration. J Biol Chem (2016) 0.76
Microarray analysis of the mammalian thromboxane receptor-Trypanosoma cruzi interaction. Cell Cycle (2011) 0.76
Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice. PLoS One (2014) 0.76
Expression of arachidonic acid-metabolizing cytochrome P450s in human megakaryocytic Dami cells. In Vitro Cell Dev Biol Anim (2013) 0.76
Lead compound design for TPR/COX dual inhibition. J Mol Model (2012) 0.76
Hydrogen peroxide elicits constriction of skeletal muscle arterioles by activating the arachidonic acid pathway. PLoS One (2014) 0.76
Thromboxane A(2) receptor stimulation promotes closure of the rat ductus arteriosus through enhancing neointima formation. PLoS One (2014) 0.76
G protein-coupled estrogen receptor inhibits vascular prostanoid production and activity. J Endocrinol (2015) 0.76
Vascular hepoxilin and trioxilins mediate vasorelaxation through TP receptor inhibition in mouse arteries. Acta Physiol (Oxf) (2015) 0.76
Interaction among COX-2, P2Y1 and GPIIIa gene variants is associated with aspirin resistance and early neurological deterioration in Chinese stroke patients. BMC Neurol (2017) 0.75
Licochalcones extracted from Glycyrrhiza inflata inhibit platelet aggregation accompanied by inhibition of COX-1 activity. PLoS One (2017) 0.75
The plasma lipidome in acute myeloid leukemia at diagnosis in relation to clinical disease features. BBA Clin (2017) 0.75
A Promising Approach to Integrally Evaluate the Disease Outcome of Cerebral Ischemic Rats Based on Multiple-Biomarker Crosstalk. Dis Markers (2017) 0.75
Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation. PLoS One (2013) 0.75
Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease. Thromb Res (2015) 0.75
Varying levels of 6-keto-prostaglandin F1α and thromboxane B2 in serum and endothelialization and hyperplasia in small-diameter grafts seeded with CD34+ bone marrow cells in canines. Exp Ther Med (2014) 0.75
Functional analysis of human thromboxane synthase polymorphic variants. Pharmacogenet Genomics (2012) 0.75
Interactions among COX-2, GPIIIa and P2Y1 variants are associated with aspirin responsiveness and adverse events in patients with ischemic stroke. Ther Adv Neurol Disord (2016) 0.75
Seawater Immersion Aggravates Burn Injury Causing Severe Blood Coagulation Dysfunction. Biomed Res Int (2016) 0.75
The expansive role of oxylipins on platelet biology. J Mol Med (Berl) (2017) 0.75