| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Translational aspects of pharmacological research into anxiety disorders: the stress-induced hyperthermia (SIH) paradigm.
|
Eur J Pharmacol
|
2008
|
1.19
|
|
2
|
Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380.
|
Psychopharmacology (Berl)
|
2011
|
1.14
|
|
3
|
Sub-optimal performance in the 5-choice serial reaction time task in rats was sensitive to methylphenidate, atomoxetine and d-amphetamine, but unaffected by the COMT inhibitor tolcapone.
|
Neurosci Res
|
2010
|
1.04
|
|
4
|
The high-affinity nAChR partial agonists varenicline and sazetidine-A exhibit reinforcing properties in rats.
|
Prog Neuropsychopharmacol Biol Psychiatry
|
2010
|
0.98
|
|
5
|
Rapid, computer vision-enabled murine screening system identifies neuropharmacological potential of two new mechanisms.
|
Front Neurosci
|
2011
|
0.98
|
|
6
|
Psychostimulant-like discriminative stimulus and locomotor sensitization properties of the wake-promoting agent modafinil in rodents.
|
Pharmacol Biochem Behav
|
2010
|
0.94
|
|
7
|
SAHA enhances synaptic function and plasticity in vitro but has limited brain availability in vivo and does not impact cognition.
|
PLoS One
|
2013
|
0.91
|
|
8
|
Impulsive action and impulsive choice are mediated by distinct neuropharmacological substrates in rat.
|
Int J Neuropsychopharmacol
|
2011
|
0.86
|
|
9
|
Pharmacological characterization of harmaline-induced tremor activity in mice.
|
Eur J Pharmacol
|
2009
|
0.85
|
|
10
|
Identification of novel α4β2-nicotinic acetylcholine receptor (nAChR) agonists based on an isoxazole ether scaffold that demonstrate antidepressant-like activity.
|
J Med Chem
|
2012
|
0.85
|
|
11
|
Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands.
|
J Med Chem
|
2012
|
0.85
|
|
12
|
The modified Geller-Seifter test in rats was insensitive to GABAB receptor positive modulation or blockade, or 5-HT1A receptor activation.
|
Behav Brain Res
|
2009
|
0.81
|
|
13
|
The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition.
|
J Psychopharmacol
|
2010
|
0.81
|
|
14
|
Comparison of the predictive validity of the mirror chamber and elevated plus maze tests in mice.
|
J Neurosci Methods
|
2010
|
0.81
|
|
15
|
Discovery of highly potent and selective α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists containing an isoxazolylpyridine ether scaffold that demonstrate antidepressant-like activity. Part II.
|
J Med Chem
|
2012
|
0.80
|
|
16
|
In vivo pharmacological effects of JZP-4, a novel anticonvulsant, in models for anticonvulsant, antimania and antidepressant activity.
|
Pharmacol Biochem Behav
|
2008
|
0.79
|
|
17
|
Chemistry, pharmacology, and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Part II.
|
J Med Chem
|
2013
|
0.79
|
|
18
|
Effect of a Novel, Orally Active Matrix Metalloproteinase-2 and -9 Inhibitor in Spinal and Trigeminal Rat Models of Neuropathic Pain.
|
J Oral Facial Pain Headache
|
2015
|
0.78
|
|
19
|
Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity.
|
Amyotroph Lateral Scler
|
2012
|
0.78
|
|
20
|
Structure-guided design of a highly selective glycogen synthase kinase-3β inhibitor: a superior neuroprotective pyrazolone showing antimania effects.
|
ChemMedChem
|
2011
|
0.77
|
|
21
|
Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem.
|
Eur J Pharmacol
|
2011
|
0.77
|
|
22
|
Characterization of maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitors as stimulators of steroidogenesis.
|
J Med Chem
|
2013
|
0.77
|
|
23
|
Anxiolytic effects of lamotrigine and JZP-4 in the elevated plus maze and in the four plate conflict test.
|
Eur J Pharmacol
|
2008
|
0.75
|