Published in J Pharm Pharmacol on April 01, 2008
Preoperative symptoms of body dysmorphic disorder determine postoperative satisfaction and quality of life in aesthetic rhinoplasty. Plast Reconstr Surg (2013) 2.71
European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinol Suppl (2010) 2.59
Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia. Proc Natl Acad Sci U S A (2002) 2.21
CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs. Nat Genet (2010) 2.12
Amphotericin B nasal lavages: not a solution for patients with chronic rhinosinusitis. J Allergy Clin Immunol (2006) 1.80
Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products. Int J Pharm (2008) 1.72
European position paper on the anatomical terminology of the internal nose and paranasal sinuses. Rhinol Suppl (2014) 1.63
High prevalence of body dysmorphic disorder symptoms in patients seeking rhinoplasty. Plast Reconstr Surg (2011) 1.58
The effect of topical amphotericin B on inflammatory markers in patients with chronic rhinosinusitis: a multicenter randomized controlled study. Laryngoscope (2009) 1.46
Mutations in CCDC39 and CCDC40 are the major cause of primary ciliary dyskinesia with axonemal disorganization and absent inner dynein arms. Hum Mutat (2013) 1.31
Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability? J Pharm Sci (2009) 1.27
Malignancies of the nasal cavity and paranasal sinuses: long-term outcome with conventional or three-dimensional conformal radiotherapy. Int J Radiat Oncol Biol Phys (2007) 1.19
Intensity-modulated radiotherapy for sinonasal cancer: improved outcome compared to conventional radiotherapy. Int J Radiat Oncol Biol Phys (2010) 1.19
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories. Eur J Pharm Sci (2008) 1.16
Primary ciliary dyskinesia, an orphan disease. Eur J Pediatr (2012) 1.14
Is the sensitivity of primary ciliary dyskinesia detection by ciliary function analysis 100%? Eur Respir J (2013) 1.09
In vitro hepatic metabolism explains higher clearance of voriconazole in children versus adults: role of CYP2C19 and flavin-containing monooxygenase 3. Drug Metab Dispos (2010) 1.08
MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques. PLoS Pathog (2012) 1.07
Primary ciliary dyskinesia: critical evaluation of clinical symptoms and diagnosis in patients with normal and abnormal ultrastructure. Orphanet J Rare Dis (2014) 1.03
Effect of pH and comedication on gastrointestinal absorption of posaconazole: monitoring of intraluminal and plasma drug concentrations. Clin Pharmacokinet (2011) 1.02
Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica. Eur J Pharm Biopharm (2007) 0.98
Drying of crystalline drug nanosuspensions-the importance of surface hydrophobicity on dissolution behavior upon redispersion. Eur J Pharm Sci (2008) 0.96
A screening study of surface stabilization during the production of drug nanocrystals. J Pharm Sci (2009) 0.96
Role of flavin-containing monooxygenase in oxidative metabolism of voriconazole by human liver microsomes. Drug Metab Dispos (2008) 0.95
Ciliary beating recovery in deficient human airway epithelial cells after lentivirus ex vivo gene therapy. PLoS Genet (2009) 0.93
Novel generic UPLC/MS/MS method for high throughput analysis applied to permeability assessment in early Drug Discovery. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.93
The importance of local eosinophilia in the surgical outcome of chronic rhinosinusitis: a 3-year prospective observational study. Am J Rhinol Allergy (2014) 0.93
Boosting of HIV protease inhibitors by ritonavir in the intestine: the relative role of cytochrome P450 and P-glycoprotein inhibition based on Caco-2 monolayers versus in situ intestinal perfusion in mice. Drug Metab Dispos (2012) 0.92
Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum. J Pharm Pharmacol (2006) 0.92
Enhanced absorption of the poorly soluble drug fenofibrate by tuning its release rate from ordered mesoporous silica. Eur J Pharm Sci (2010) 0.92
Llama antibody fragments have good potential for application as HIV type 1 topical microbicides. AIDS Res Hum Retroviruses (2011) 0.91
Solubility increases associated with crystalline drug nanoparticles: methodologies and significance. Mol Pharm (2010) 0.90
In vivo, in vitro and in silico methods for small molecule transfer across the BBB. J Pharm Sci (2009) 0.90
Localization of candidate regions for a novel gene for Kartagener syndrome. Eur J Hum Genet (2006) 0.89
Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability. Eur J Pharm Biopharm (2010) 0.89
Formulate-ability of ten compounds with different physicochemical profiles in SMEDDS. Eur J Pharm Sci (2009) 0.89
Excipient-mediated supersaturation stabilization in human intestinal fluids. Mol Pharm (2011) 0.89
A randomized controlled trial of mometasone furoate nasal spray for the treatment of nasal polyposis. Arch Otolaryngol Head Neck Surg (2006) 0.88
Itraconazole/TPGS/Aerosil200 solid dispersions: characterization, physical stability and in vivo performance. Eur J Pharm Sci (2009) 0.88
Evaluation of gastrointestinal drug supersaturation and precipitation: strategies and issues. Int J Pharm (2012) 0.88
Cardiovascular disease relates to intestinal uptake of p-cresol in patients with chronic kidney disease. BMC Nephrol (2014) 0.88
Physical state of poorly water soluble therapeutic molecules loaded into SBA-15 ordered mesoporous silica carriers: a case study with itraconazole and ibuprofen. Langmuir (2008) 0.88
Effects of T cell-induced colonic inflammation on epithelial barrier function. Inflamm Bowel Dis (2010) 0.88
Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters. Int J Pharm (2010) 0.87
Screening tools for body dysmorphic disorder in a cosmetic surgery setting. Laryngoscope (2011) 0.86
Sandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity. Expert Opin Drug Metab Toxicol (2013) 0.86
In vitro evaluation of viability, integrity, and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides. Antimicrob Agents Chemother (2010) 0.86
In situ intestinal perfusion in knockout mice demonstrates inhibition of intestinal p-glycoprotein by ritonavir causing increased darunavir absorption. Drug Metab Dispos (2010) 0.86
Series of extranodal natural killer/T-cell lymphoma, nasal type, with periorbital involvement. Orbit (2014) 0.86
Biochemical characterization of malate synthase G of P. aeruginosa. BMC Biochem (2009) 0.86
Sodium fluorescein is a probe substrate for hepatic drug transport mediated by OATP1B1 and OATP1B3. J Pharm Sci (2011) 0.86
High-speed digital imaging method for ciliary beat frequency measurement. J Pharm Pharmacol (2005) 0.86
Enhanced release of itraconazole from ordered mesoporous SBA-15 silica materials. Chem Commun (Camb) (2007) 0.85
Prevalence and determinants of allergic diseases in a Congolese population. Int Forum Allergy Rhinol (2012) 0.85
Ordered mesoporous silica material SBA-15: a broad-spectrum formulation platform for poorly soluble drugs. J Pharm Sci (2009) 0.85
Thiolated chitosan nanoparticles for the nasal administration of leuprolide: bioavailability and pharmacokinetic characterization. Int J Pharm (2012) 0.85
Diagnostic accuracy of nitric oxide measurements to detect primary ciliary dyskinesia. Eur J Clin Invest (2014) 0.85
Interaction of eight HIV protease inhibitors with the canalicular efflux transporter ABCC2 (MRP2) in sandwich-cultured rat and human hepatocytes. Biopharm Drug Dispos (2010) 0.84
Long-term follow-up of 44 patients with adenocarcinoma of the nasal cavity and sinuses primarily treated with endoscopic resection followed by radiotherapy. Head Neck (2010) 0.84
Inhibitory effect of fruit extracts on P-glycoprotein-related efflux carriers: an in-vitro screening. J Pharm Pharmacol (2002) 0.83
CADA, a potential anti-HIV microbicide that specifically targets the cellular CD4 receptor. Curr HIV Res (2008) 0.83
Usefulness of a novel Caco-2 cell perfusion system. I. In vitro prediction of the absorption potential of passively diffused compounds. J Pharm Sci (2004) 0.83
Early identification of availability issues for poorly water-soluble microbicide candidates in biorelevant media: a case study with saquinavir. Antiviral Res (2011) 0.83
In vitro profiling of the vaginal permeation potential of anti-HIV microbicides and the influence of formulation excipients. Antiviral Res (2012) 0.83
Equilibrium drug solubility measurements in 96-well plates reveal similar drug solubilities in phosphate buffer pH 6.8 and human intestinal fluid. Int J Pharm (2010) 0.83
Species-specific interaction of HIV protease inhibitors with accumulation of cholyl-glycylamido-fluorescein (CGamF) in sandwich-cultured hepatocytes. J Pharm Sci (2010) 0.83
Iron deficiency after Roux-en-Y gastric bypass: insufficient iron absorption from oral iron supplements. Obes Surg (2014) 0.82
High-throughput study of phenytoin solid dispersions: formulation using an automated solvent casting method, dissolution testing, and scaling-up. J Comb Chem (2008) 0.82
Drug supersaturation in simulated and human intestinal fluids representing different nutritional states. J Pharm Sci (2010) 0.82
PXR/CYP3A4-humanized mice for studying drug-drug interactions involving intestinal P-glycoprotein. Mol Pharm (2013) 0.82
IL-10- and IL-12-independent down-regulation of allergic sensitization by stimulation of CD40 signaling. J Immunol (2006) 0.82
Cellular accumulation of cholyl-glycylamido-fluorescein in sandwich-cultured rat hepatocytes: kinetic characterization, transport mechanisms, and effect of human immunodeficiency virus protease inhibitors. Drug Metab Dispos (2008) 0.82
Incomplete desorption of liquid excipients reduces the in vitro and in vivo performance of self-emulsifying drug delivery systems solidified by adsorption onto an inorganic mesoporous carrier. Mol Pharm (2012) 0.81
Alternative matrix formers for nanosuspension solidification: Dissolution performance and X-ray microanalysis as an evaluation tool for powder dispersion. Eur J Pharm Sci (2008) 0.81
Comparison of the complexation between methylprednisolone and different cyclodextrins in solution by 1H-NMR and molecular modeling studies. J Pharm Sci (2010) 0.81
Intestinal drug solubility estimation based on simulated intestinal fluids: comparison with solubility in human intestinal fluids. Eur J Pharm Sci (2011) 0.81
Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: a case study with amprenavir. J Pharm Sci (2006) 0.81
Intestinal perfusion with mesenteric blood sampling in wild-type and knockout mice: evaluation of a novel tool in biopharmaceutical drug profiling. Drug Metab Dispos (2009) 0.80
Development and in vitro evaluation of chloroquine gels as microbicides against HIV-1 infection. Virology (2008) 0.80
Microcrystalline cellulose, a useful alternative for sucrose as a matrix former during freeze-drying of drug nanosuspensions - a case study with itraconazole. Eur J Pharm Biopharm (2008) 0.80
In vitro polarized transport of L-phenylalanine in human nasal epithelium and partial characterization of the amino acid transporters involved. Pharm Res (2003) 0.80
Nasal corticosteroid treatment reduces substance P levels in tear fluid in allergic rhinoconjunctivitis. Ann Allergy Asthma Immunol (2012) 0.80
Preventing release in the acidic environment of the stomach via occlusion in ordered mesoporous silica enhances the absorption of poorly soluble weakly acidic drugs. J Pharm Sci (2011) 0.80
Development of thiolated poly(acrylic acid) microparticles for the nasal administration of exenatide. Drug Dev Ind Pharm (2013) 0.80
Vaginal expression of efflux transporters and the potential impact on the disposition of microbicides in vitro and in rabbits. Mol Pharm (2014) 0.80
Combined use of ordered mesoporous silica and precipitation inhibitors for improved oral absorption of the poorly soluble weak base itraconazole. Eur J Pharm Biopharm (2010) 0.80
Pharmacokinetics of Posaconazole Oral Suspension in Children Dosed According to Body Surface Area. Pediatr Infect Dis J (2016) 0.79
Post-operative intensity-modulated radiotherapy for malignancies of the nasal cavity and paranasal sinuses. Radiother Oncol (2007) 0.79
Specific antibody modulates absorptive transport and metabolic activation of benzo[a]pyrene across Caco-2 monolayers. J Pharmacol Exp Ther (2005) 0.79
Lipid-based formulations solidified via adsorption onto the mesoporous carrier Neusilin® US2: effect of drug type and formulation composition on in vitro pharmaceutical performance. J Pharm Sci (2014) 0.79
Metabolism of stevioside in pigs and intestinal absorption characteristics of stevioside, rebaudioside A and steviol. Food Chem Toxicol (2003) 0.78
The effect of food components on the absorption of P-gp substrates: a review. J Pharm Pharmacol (2003) 0.78
P-glycoprotein attenuating effect of human intestinal fluid. Pharm Res (2003) 0.78
Nasal absorption enhancement strategies for therapeutic peptides: an in vitro study using cultured human nasal epithelium. Int J Pharm (2002) 0.78
Mechanistic appraisal of the effects of some protease inhibitors on ciliary beat frequency in a sequential cell culture system of human nasal epithelium. Eur J Pharm Biopharm (2003) 0.78
Apricot extract inhibits the P-gp-mediated efflux of talinolol. J Pharm Sci (2002) 0.78
Results of endoscopic resection followed by radiotherapy for primarily diagnosed adenocarcinomas of the paranasal sinuses. Head Neck (2008) 0.78
Short-time cold dry air exposure: a useful diagnostic tool for nasal hyperresponsiveness. Laryngoscope (2012) 0.78