Frank Skorpen

Author PubWeight™ 78.99‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 2008 16.10
2 Lung cancer susceptibility locus at 5p15.33. Nat Genet 2008 5.99
3 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet 2009 5.62
4 Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA. Nature 2003 5.49
5 Investigation of the fine structure of European populations with applications to disease association studies. Eur J Hum Genet 2008 3.65
6 CUBN is a gene locus for albuminuria. J Am Soc Nephrol 2011 2.70
7 Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner. J Mol Diagn 2005 2.66
8 The association between headache and Val158Met polymorphism in the catechol-O-methyltransferase gene: the HUNT Study. J Headache Pain 2006 2.27
9 hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup. J Biol Chem 2002 2.18
10 The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients. Pain 2005 2.00
11 Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals. Int J Epidemiol 2009 1.97
12 Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum Mol Genet 2012 1.77
13 Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. Pain 2006 1.72
14 Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain. Mol Pain 2008 1.41
15 A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity. Clin Pharmacol Ther 2004 1.39
16 Health care providers underestimate symptom intensities of cancer patients: a multicenter European study. Health Qual Life Outcomes 2010 1.34
17 Variation in the COMT gene: implications for pain perception and pain treatment. Pharmacogenomics 2009 1.07
18 Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium. Carcinogenesis 2012 1.05
19 Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy. Eur J Clin Pharmacol 2002 1.04
20 Clinical and genetic factors associated with nausea and vomiting in cancer patients receiving opioids. Eur J Cancer 2011 1.01
21 No association between chronic musculoskeletal complaints and Val158Met polymorphism in the Catechol-O-methyltransferase gene. The HUNT study. BMC Musculoskelet Disord 2006 0.98
22 High systolic blood pressure is associated with Val/Val genotype in the catechol-o-methyltransferase gene. The Nord-Trøndelag Health Study (HUNT). Am J Hypertens 2007 0.98
23 Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals. PLoS Genet 2011 0.94
24 Genetic heterogeneity in latent autoimmune diabetes is linked to various degrees of autoimmune activity: results from the Nord-Trøndelag Health Study. Diabetes 2009 0.92
25 Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review. J Genet 2011 0.90
26 Genetic analysis of the murine mu opioid receptor: increased complexity of Oprm gene splicing. J Mol Med (Berl) 2004 0.89
27 P-selectin genotype is associated with the development of cancer cachexia. EMBO Mol Med 2012 0.89
28 Multiple Loci modulate opioid therapy response for cancer pain. Clin Cancer Res 2011 0.86
29 Association between a 15q25 gene variant, nicotine-related habits, lung cancer and COPD among 56,307 individuals from the HUNT study in Norway. Eur J Hum Genet 2013 0.85
30 Induction of uncoupling protein 2 mRNA in beta-cells is stimulated by oxidation of fatty acids but not by nutrient oversupply. Endocrinology 2002 0.83
31 Depression and anxiety in relation to catechol-O-methyltransferase Val158Met genotype in the general population: the Nord-Trøndelag Health Study (HUNT). BMC Psychiatry 2008 0.82
32 The impact of the catechol-O-methyltransferase Val158Met polymorphism on survival in the general population--the HUNT study. BMC Med Genet 2007 0.81
33 Is there a genetic cause of appetite loss?-an explorative study in 1,853 cancer patients. J Cachexia Sarcopenia Muscle 2012 0.79
34 Overexpression of transcription factor AP-2 stimulates the PA promoter of the human uracil-DNA glycosylase (UNG) gene through a mechanism involving derepression. DNA Repair (Amst) 2009 0.78
35 [Genetic variation-- important for the clinical effect of opioids?]. Tidsskr Nor Laegeforen 2005 0.77
36 Prevalence of ZnT8 antibody in relation to phenotype and SLC30A8 polymorphism in adult autoimmune diabetes: results from the HUNT study, Norway. Autoimmunity 2012 0.77
37 The N-terminally truncated µ3 and µ3-like opioid receptors are transcribed from a novel promoter upstream of exon 2 in the human OPRM1 gene. PLoS One 2013 0.77
38 Lack of association between genetic variability and multiple pain-related outcomes in a large cohort of patients with advanced cancer: the European Pharmacogenetic Opioid Study (EPOS). BMJ Support Palliat Care 2012 0.76
39 Transepithelial transport of morphine and mannitol in Caco-2 cells: the influence of chitosans of different molecular weights and degrees of acetylation. J Pharm Pharmacol 2006 0.76
40 Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet 2017 0.75
41 COMT genotypes and use of antipsychotic medication: linking population-based prescription database to the HUNT study. Pharmacoepidemiol Drug Saf 2008 0.75
42 Genetic findings related to pain and analgesics-why are they so inconsistent? Pain 2016 0.75
43 Marked over expression of uncoupling protein-2 in beta cells exerts minor effects on mitochondrial metabolism. Biochem Biophys Res Commun 2012 0.75
44 Variability in UDP-glucuronosyltransferase genes and morphine metabolism: observations from a cross-sectional multicenter study in advanced cancer patients with pain. Pharmacogenet Genomics 2013 0.75
45 OP006. A preeclampsia genome-wide linkage scan in norwegian families. Pregnancy Hypertens 2013 0.75
46 A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma. Am J Hum Genet 2011 0.75