| Rank | Title | Journal | Year | PubWeight™‹?› |
|---|---|---|---|---|
| 1 | Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers. | J Clin Oncol | 2008 | 4.82 |
| 2 | Potent and selective mitogen-activated protein kinase kinase (MEK) 1,2 inhibitors. 1. 4-(4-bromo-2-fluorophenylamino)-1- methylpyridin-2(1H)-ones. | J Med Chem | 2006 | 1.22 |
| 3 | Prodrug thiamine analogs as inhibitors of the enzyme transketolase. | Bioorg Med Chem Lett | 2007 | 0.87 |