Shinji Saiki

Author PubWeight™ 39.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J Cell Biol 2010 7.62
2 Lysosomal positioning coordinates cellular nutrient responses. Nat Cell Biol 2011 4.96
3 Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nat Chem Biol 2008 4.19
4 Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications. Curr Top Dev Biol 2006 3.02
5 Huntington's disease: from pathology and genetics to potential therapies. Biochem J 2008 2.41
6 Mutations in the gene PRRT2 cause paroxysmal kinesigenic dyskinesia with infantile convulsions. Cell Rep 2011 2.17
7 A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. Hum Mol Genet 2007 2.03
8 PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy. FEBS Lett 2010 1.79
9 A neuropathological study of autosomal-dominant chorea-acanthocytosis with a mutation of VPS13A. Acta Neuropathol 2008 1.59
10 Novel pathogenic mutations and copy number variations in the VPS13A gene in patients with chorea-acanthocytosis. Am J Med Genet B Neuropsychiatr Genet 2011 1.08
11 Neurological deficits are associated with increased brain calcinosis, hypoperfusion, and hypometabolism in idiopathic basal ganglia calcification. Mov Disord 2007 1.00
12 Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects. Neurobiol Dis 2010 0.99
13 Genetic mutations and functions of PINK1. Trends Pharmacol Sci 2011 0.90
14 Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD. Neurosci Lett 2010 0.88
15 Effect of a paraneoplastic cerebellar degeneration-associated neural protein on B-myb promoter activity. Neurobiol Dis 2004 0.84
16 ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons. FEBS Lett 2013 0.83
17 DJ-1 associates with synaptic membranes. Neurobiol Dis 2011 0.81
18 Binding of the ELAV-like protein in murine autoimmune T-cells to the nonameric AU-rich element in the 3' untranslated region of CD154 mRNA. Mol Immunol 2003 0.80
19 Type-2 astrocyte-like cells are more resistant than oligodendrocyte-like cells against non-N-methyl-D-aspartate glutamate receptor-mediated excitotoxicity. J Neurosci Res 2002 0.78
20 Induction of humoral responses specific for paraneoplastic cerebellar degeneration-associated antigen by whole recombinant yeast immunization. J Autoimmun 2005 0.76
21 Mutation in the CHAC gene in a family of autosomal dominant chorea-acanthocytosis. Neurology 2012 0.75
22 Huntington's disease-like 2 can present as chorea-acanthocytosis. Neurology 2004 0.75
23 [The pathomechanisms of young-onset Parkinson's disease (PD), approach to the causes of PD form the mechanisms of insulin secretion system]. Rinsho Shinkeigaku 2011 0.75
24 Ictal alteration of 99mTc ECD SPECT imaging in a patient with secondary paroxysmal kinesigenic dyskinesia caused by hyperglycemia. Rinsho Shinkeigaku 2005 0.75