| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Serotonin receptor 1A knockout: an animal model of anxiety-related disorder.
|
Proc Natl Acad Sci U S A
|
1998
|
2.54
|
|
2
|
Differences between males and females in rates of serotonin synthesis in human brain.
|
Proc Natl Acad Sci U S A
|
1997
|
2.50
|
|
3
|
Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists.
|
Trends Neurosci
|
1996
|
2.22
|
|
4
|
Assessment of the serotonin and norepinephrine reuptake blocking properties of duloxetine in healthy subjects.
|
Neuropsychopharmacology
|
2001
|
2.00
|
|
5
|
Autoregulation of serotonin neurons: role in antidepressant drug action.
|
Pharmacol Rev
|
1999
|
1.69
|
|
6
|
Long-term antidepressant treatments result in a tonic activation of forebrain 5-HT1A receptors.
|
J Neurosci
|
1998
|
1.56
|
|
7
|
Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function.
|
Proc Natl Acad Sci U S A
|
2001
|
1.30
|
|
8
|
The serotonergic and noradrenergic systems of the hippocampus: their interactions and the effects of antidepressant treatments.
|
Brain Res Brain Res Rev
|
1997
|
1.25
|
|
9
|
Effects of a selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: electrophysiological studies in the rat brain.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1986
|
1.22
|
|
10
|
Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments. An in vivo electrophysiologic study in the rat.
|
Neuropsychopharmacology
|
1991
|
1.13
|
|
11
|
Electrophysiological investigations on the effect of repeated zimelidine administration on serotonergic neurotransmission in the rat.
|
J Neurosci
|
1983
|
1.10
|
|
12
|
Sustained administration of pramipexole modifies the spontaneous firing of dopamine, norepinephrine, and serotonin neurons in the rat brain.
|
Neuropsychopharmacology
|
2008
|
1.09
|
|
13
|
Brain Regional alpha-[11C]methyl-L-tryptophan trapping in impulsive subjects with borderline personality disorder.
|
Am J Psychiatry
|
2001
|
1.06
|
|
14
|
Modulation of noradrenergic neuronal firing by selective serotonin reuptake blockers.
|
Br J Pharmacol
|
1999
|
1.06
|
|
15
|
Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study.
|
J Pharmacol Exp Ther
|
2001
|
1.05
|
|
16
|
Modulation of the firing activity of noradrenergic neurones in the rat locus coeruleus by the 5-hydroxtryptamine system.
|
Br J Pharmacol
|
1997
|
1.03
|
|
17
|
Effect of pindolol on the function of pre- and postsynaptic 5-HT1A receptors: in vivo microdialysis and electrophysiological studies in the rat brain.
|
Neuropsychopharmacology
|
1996
|
1.01
|
|
18
|
Effects on mood of acute phenylalanine/tyrosine depletion in healthy women.
|
Neuropsychopharmacology
|
2000
|
0.99
|
|
19
|
Desensitization of the neuronal 5-HT carrier following its long-term blockade.
|
J Neurosci
|
1994
|
0.99
|
|
20
|
Functional and pharmacological characterization of the modulatory role of serotonin on the firing activity of locus coeruleus norepinephrine neurons.
|
Brain Res
|
2001
|
0.98
|
|
21
|
Effect of the selective noradrenergic reuptake inhibitor reboxetine on the firing activity of noradrenaline and serotonin neurons.
|
Eur J Neurosci
|
2001
|
0.97
|
|
22
|
Modification of norepinephrine and serotonin, but not dopamine, neuron firing by sustained bupropion treatment.
|
Psychopharmacology (Berl)
|
2001
|
0.97
|
|
23
|
In vivo electrophysiological evidence for the regulatory role of autoreceptors on serotonergic terminals.
|
J Neurosci
|
1986
|
0.96
|
|
24
|
Effect of atypical antipsychotic drugs on 5-HT2 receptors in the rat orbito-frontal cortex: an in vivo electrophysiological study.
|
Psychopharmacology (Berl)
|
1999
|
0.96
|
|
25
|
The monomeric guanosine triphosphatase rab4 controls an essential step on the pathway of receptor-mediated antigen processing in B cells.
|
J Exp Med
|
1998
|
0.94
|
|
26
|
Tandospirone and its metabolite, 1-(2-pyrimidinyl)-piperazine--I. Effects of acute and long-term administration of tandospirone on serotonin neurotransmission.
|
Neuropharmacology
|
1991
|
0.94
|
|
27
|
Effects of the co-administration of mirtazapine and paroxetine on serotonergic neurotransmission in the rat brain.
|
Eur Neuropsychopharmacol
|
2000
|
0.93
|
|
28
|
Effect of acute, short- and long-term milnacipran administration on rat locus coeruleus noradrenergic and dorsal raphe serotonergic neurons.
|
Neuropharmacology
|
1998
|
0.92
|
|
29
|
Activation of 5-HT2A receptors potentiates pain produced by inflammatory mediators.
|
Neuropharmacology
|
1996
|
0.92
|
|
30
|
Noradrenergic modulation of central serotonergic neurotransmission: acute and long-term actions of mirtazapine.
|
Int Clin Psychopharmacol
|
1995
|
0.91
|
|
31
|
In vivo electrophysiological evidence for tonic activation by endogenous noradrenaline of alpha 2-adrenoceptors on 5-hydroxytryptamine terminals in the rat hippocampus.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1993
|
0.90
|
|
32
|
Electrophysiologically-identified serotonin receptors in the rat CNS. Effect of antidepressant treatment.
|
Neuropharmacology
|
1984
|
0.90
|
|
33
|
Electrophysiologic evidence for desensitization of alpha 2-adrenoceptors on serotonin terminals following long-term treatment with drugs increasing norepinephrine synaptic concentration.
|
Neuropsychopharmacology
|
1994
|
0.89
|
|
34
|
Serotonin (1A) receptor ligands act on norepinephrine neuron firing through excitatory amino acid and GABA(A) receptors: a microiontophoretic study in the rat locus coeruleus.
|
Synapse
|
2001
|
0.89
|
|
35
|
Effects of long-term desipramine administration on noradrenergic neurotransmission: electrophysiological studies in the rat brain.
|
J Pharmacol Exp Ther
|
1991
|
0.89
|
|
36
|
Alteration of serotonin release in the guinea pig orbito-frontal cortex by selective serotonin reuptake inhibitors. Relevance to treatment of obsessive-compulsive disorder.
|
Neuropsychopharmacology
|
1995
|
0.89
|
|
37
|
Effect of acute and repeated versus sustained administration of the 5-HT1A receptor agonist ipsapirone: electrophysiological studies in the rat hippocampus and dorsal raphe.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1997
|
0.89
|
|
38
|
In vivo electrophysiological examination of 5-HT2 responses in 5-HT2C receptor mutant mice.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2000
|
0.88
|
|
39
|
Modification of serotonergic and noradrenergic neurotransmissions by repeated administration of monoamine oxidase inhibitors: electrophysiological studies in the rat central nervous system.
|
J Pharmacol Exp Ther
|
1986
|
0.88
|
|
40
|
In vivo electrophysiological characterization of 5-HT receptors in the guinea pig head of caudate nucleus and orbitofrontal cortex.
|
Neuropharmacology
|
1997
|
0.88
|
|
41
|
Modulation by sigma ligands of N-methyl-D-aspartate-induced [3H]noradrenaline release in the rat hippocampus: G-protein dependency.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1992
|
0.88
|
|
42
|
Serotoninergic but not noradrenergic neurons in rat central nervous system adapt to long-term treatment with monoamine oxidase inhibitors.
|
Neuroscience
|
1985
|
0.88
|
|
43
|
Effects of the two antidepressant drugs mianserin and indalpine on the serotonergic system: single-cell studies in the rat.
|
Psychopharmacology (Berl)
|
1984
|
0.87
|
|
44
|
Venlafaxine: discrepancy between in vivo 5-HT and NE reuptake blockade and affinity for reuptake sites.
|
Synapse
|
1999
|
0.87
|
|
45
|
Serotonin1A receptor activation by flesinoxan in humans. Body temperature and neuroendocrine responses.
|
Neuropsychopharmacology
|
1995
|
0.87
|
|
46
|
Acute tyrosine depletion and alcohol ingestion in healthy women.
|
Alcohol Clin Exp Res
|
2000
|
0.86
|
|
47
|
Acute and long-term actions of the antidepressant drug mirtazapine on central 5-HT neurotransmission.
|
J Affect Disord
|
1998
|
0.86
|
|
48
|
Cisapride for the treatment of nausea produced by selective serotonin reuptake inhibitors.
|
Am J Psychiatry
|
1994
|
0.86
|
|
49
|
Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain.
|
J Pharmacol Exp Ther
|
1996
|
0.86
|
|
50
|
Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments.
|
Neuropsychopharmacology
|
2000
|
0.86
|
|
51
|
Potentiation by (-)Pindolol of the activation of postsynaptic 5-HT(1A) receptors induced by venlafaxine.
|
Neuropsychopharmacology
|
2000
|
0.85
|
|
52
|
Electrophysiological characterization of the effect of long-term duloxetine administration on the rat serotonergic and noradrenergic systems.
|
J Pharmacol Exp Ther
|
1998
|
0.85
|
|
53
|
Short-term lithium administration enhances serotonergic neurotransmission: electrophysiological evidence in the rat CNS.
|
Eur J Pharmacol
|
1985
|
0.85
|
|
54
|
Effects of acute and chronic administration of the serotonin1A agonist buspirone on serotonin synthesis in the rat brain.
|
J Neurochem
|
1999
|
0.85
|
|
55
|
Depressive relapse following acute tryptophan depletion in patients with major depressive disorder.
|
J Psychopharmacol
|
2000
|
0.84
|
|
56
|
Effect of long-term administration of antidepressant treatments on serotonin release in brain regions involved in obsessive-compulsive disorder.
|
Biol Psychiatry
|
1999
|
0.84
|
|
57
|
Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice.
|
Neuroreport
|
1995
|
0.84
|
|
58
|
Effects of the selective norepinephrine reuptake inhibitor reboxetine on norepinephrine and serotonin transmission in the rat hippocampus.
|
Neuropsychopharmacology
|
2001
|
0.84
|
|
59
|
Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: I. in vivo electrophysiological studies in the rat.
|
Neuropharmacology
|
2000
|
0.83
|
|
60
|
Reduction in serotonin synthesis following acute and chronic treatments with paroxetine, a selective serotonin reuptake inhibitor, in rat brain: an autoradiographic study with alpha-[14C]methyl-L-tryptophan(2).
|
Biochem Pharmacol
|
2001
|
0.83
|
|
61
|
Effect of neurokinin-I receptor antagonists on the function of 5-HT and noradrenaline neurons.
|
Neuroreport
|
2000
|
0.83
|
|
62
|
Effect of the alpha-2 adrenoceptor antagonist mirtazapine on the 5-hydroxytryptamine system in the rat brain.
|
J Pharmacol Exp Ther
|
1996
|
0.83
|
|
63
|
Effect of desipramine and amphetamine on noradrenergic neurotransmission: electrophysiological studies in the rat brain.
|
Eur J Pharmacol
|
1992
|
0.83
|
|
64
|
Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission.
|
Biol Psychiatry
|
2001
|
0.83
|
|
65
|
Effects of sustained (+/-)pindolol administration on serotonin neurotransmission in rats.
|
J Psychiatry Neurosci
|
2000
|
0.82
|
|
66
|
Characterization of 5-hydroxytryptamine1A properties of flesinoxan: in vivo electrophysiology and hypothermia study.
|
Neuropharmacology
|
1995
|
0.82
|
|
67
|
Effect of chronic tricylic antidepressant treatment on the serotoninergic autoreceptor: a microiontophoretic study in the rat.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1980
|
0.82
|
|
68
|
Characterization of the 5-hydroxytryptamine receptor modulating the release of 5-[3H]hydroxytryptamine in slices of the human neocortex.
|
J Neurochem
|
1992
|
0.82
|
|
69
|
Full agonistic properties of BAY x 3702 on presynaptic and postsynaptic 5-HT1A receptors electrophysiological studies in the rat hippocampus and dorsal raphe.
|
J Pharmacol Exp Ther
|
1998
|
0.81
|
|
70
|
Venlafaxine in treatment-resistant major depression: a Canadian multicenter, open-label trial.
|
J Clin Psychopharmacol
|
1999
|
0.81
|
|
71
|
Electrophysiological effects of the co-administration of escitalopram and bupropion on rat serotonin and norepinephrine neurons.
|
J Psychopharmacol
|
2008
|
0.81
|
|
72
|
5-HT1D receptors regulate 5-HT release in the rat raphe nuclei. In vivo voltammetry and in vitro superfusion studies.
|
Neuropsychopharmacology
|
1995
|
0.80
|
|
73
|
The effect of tryptophan depletion on mood in medication-free, former patients with major affective disorder.
|
Neuropsychopharmacology
|
1997
|
0.80
|
|
74
|
Effect of prolonged administration of tianeptine on 5-HT neurotransmission: an electrophysiological study in the rat hippocampus and dorsal raphe.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1995
|
0.80
|
|
75
|
Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: II. In vitro studies in the rat.
|
Neuropharmacology
|
2000
|
0.80
|
|
76
|
Response of the norepinephrine system to antidepressant drugs.
|
CNS Spectr
|
2001
|
0.80
|
|
77
|
Effect of long-term administration of duloxetine on the function of serotonin and noradrenaline terminals in the rat brain.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1998
|
0.80
|
|
78
|
Modification of serotonergic neuron properties by long-term treatment with serotonin reuptake blockers.
|
J Clin Psychiatry
|
1990
|
0.80
|
|
79
|
Role of cholinergic and GABAergic systems in the feedback inhibition of dorsal raphe 5-HT neurons.
|
Neuroreport
|
2000
|
0.80
|
|
80
|
Effects of long-term treatment with the alpha 2-adrenoceptor antagonist mirtazapine on 5-HT neurotransmission.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1997
|
0.79
|
|
81
|
Pre- and postsynaptic effects of zimelidine and norzimelidine on the serotoninergic system: single cell studies in the rat.
|
Acta Psychiatr Scand Suppl
|
1981
|
0.79
|
|
82
|
Agonist occupation of serotonin1A receptors in the rat hippocampus prevents their inactivation by pertussis toxin.
|
Neuroscience
|
1994
|
0.79
|
|
83
|
Activation of 5-HT3 receptors enhances the electrically evoked release of [3H]noradrenaline in rat brain limbic structures.
|
Eur J Pharmacol
|
1994
|
0.79
|
|
84
|
Effect of sustained administration of the 5-HT1A receptor agonist flesinoxan on rat 5-HT neurotransmission.
|
Eur Neuropsychopharmacol
|
1999
|
0.79
|
|
85
|
Resiliency of monoaminergic systems: the 80% rule and its relevance to drug development.
|
J Psychopharmacol
|
2008
|
0.79
|
|
86
|
Desensitization of terminal 5-HT autoreceptors by 5-HT reuptake blockers.
|
Arch Gen Psychiatry
|
1991
|
0.79
|
|
87
|
Persisting sensitization of the behavioural response to formalin-induced injury in the rat through activation of serotonin2A receptors.
|
Neuroscience
|
1997
|
0.79
|
|
88
|
Effects of antidepressant treatments on 5-HT neurotransmission: electrophysiological and clinical studies.
|
Adv Biochem Psychopharmacol
|
1984
|
0.78
|
|
89
|
Effect of ergotamine on serotonin-mediated responses in the rodent and human brain.
|
Neuropsychopharmacology
|
1998
|
0.78
|
|
90
|
Regulation of 5-hydroxytryptamine release from rat midbrain raphe nuclei by 5-hydroxytryptamine1D receptors: effect of tetrodotoxin, G protein inactivation and long-term antidepressant administration.
|
J Pharmacol Exp Ther
|
1996
|
0.78
|
|
91
|
Electrophysiological examination of the effects of sustained flibanserin administration on serotonin receptors in rat brain.
|
Br J Pharmacol
|
1999
|
0.78
|
|
92
|
In vivo electrophysiological assessment of the putative antidepressant Wf-516 in the rat raphe dorsalis, locus coeruleus and hippocampus.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2007
|
0.78
|
|
93
|
Modulation of the firing activity of rat serotonin and noradrenaline neurons by (+/-)pindolol.
|
Biol Psychiatry
|
1999
|
0.77
|
|
94
|
In vivo electrophysiological assessment of the agonistic properties of flibanserin at pre- and postsynaptic 5-HT1A receptors in the rat brain.
|
Synapse
|
1998
|
0.77
|
|
95
|
In vivo presynaptic modulation of serotonergic neurotransmission in the rat hippocampus by diazepam.
|
Eur J Pharmacol
|
1989
|
0.77
|
|
96
|
Pre- and post-synaptic effects of the 5-HT3 agonist 2-methyl-5-HT on the 5-HT system in the rat brain.
|
Synapse
|
1995
|
0.77
|
|
97
|
Assessment of the serotonin reuptake blocking property of YM992: electrophysiological studies in the rat hippocampus and dorsal raphe.
|
Synapse
|
1999
|
0.77
|
|
98
|
Effect of the reversible monoamine oxidase-A inhibitor befloxatone on the rat 5-hydroxytryptamine neurotransmission.
|
Eur J Pharmacol
|
1998
|
0.77
|
|
99
|
Effect of acute and prolonged tianeptine administration on the 5-HT transporter: electrophysiological, biochemical and radioligand binding studies in the rat brain.
|
Naunyn Schmiedebergs Arch Pharmacol
|
1995
|
0.77
|
|
100
|
An ideal trial to test differential onset of antidepressant effect.
|
J Clin Psychiatry
|
2001
|
0.76
|
|
101
|
A comparison of the effects of acute tryptophan depletion and acute phenylalanine/tyrosine depletion in healthy women.
|
Adv Exp Med Biol
|
1999
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0.76
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102
|
Blockade of 5-hydroxytryptamine and noradrenaline uptake by venlafaxine: a comparative study with paroxetine and desipramine.
|
Br J Pharmacol
|
1998
|
0.76
|
|
103
|
Effects of chronic antidepressant drug administration and electroconvulsive shock on locus coeruleus electrophysiologic activity.
|
Biol Psychiatry
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2001
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0.76
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104
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Autoregulatory properties of dorsal raphe 5-HT neurons: possible role of electrotonic coupling and 5-HT1D receptors in the rat brain.
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Synapse
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1996
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0.76
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105
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Electrophysiological studies on the effect of long-term 5-HT reuptake inhibition on the function of 5-HT neurons.
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Clin Neuropharmacol
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1992
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0.76
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106
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Clarifications on the effects of 5-HT1A agonists and selective 5-HT reuptake inhibitors on the 5-HT system.
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Neuropsychopharmacology
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1996
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0.76
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107
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Effect of long-term administration of antidepressant drugs on the 5-HT3 receptors that enhance the electrically evoked release of [3H]noradrenaline in the rat hippocampus.
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Eur J Pharmacol
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1994
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0.76
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108
|
Effects of quipazine on pre- and postsynaptic serotonin receptors: single cell studies in the rat CNS.
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Neuropharmacology
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1983
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0.75
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109
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Partial agonistic activity of R- and S-enantiomers of 8-OH-DPAT at 5-HT1A receptors.
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J Psychiatry Neurosci
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1996
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0.75
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110
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Delayed effects of spiperone on serotonin1A receptors in the dorsal hippocampus of rats.
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J Psychiatry Neurosci
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1993
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0.75
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111
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Functional characterization of 5-HT1D autoreceptors on the modulation of 5-HT release in guinea-pig mesencephalic raphe, hippocampus and frontal cortex.
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Br J Pharmacol
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1996
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0.75
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112
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Effect of repeated amiflamine administration on serotonergic and noradrenergic neurotransmission: electrophysiological studies in the rat CNS.
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Naunyn Schmiedebergs Arch Pharmacol
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1986
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0.75
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113
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Lack of efficacy of lithium augmentation in obsessive-compulsive disorder: the perspective of different regional effects of lithium on serotonin release in the central nervous system.
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J Clin Psychopharmacol
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1992
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0.75
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114
|
Serotonergic drugs and panic disorder.
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J Psychiatry Neurosci
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2000
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0.75
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115
|
Benzodiazepine receptors modulating serotonergic neurotransmission in rat hippocampus do not desensitize after long-term diazepam treatment.
|
Brain Res
|
1990
|
0.75
|
|
116
|
Benzodiazepine receptors modulate 5-hydroxytryptamine neurotransmission in the rat hippocampus: in vivo electrophysiological evidence.
|
J Pharmacol Exp Ther
|
1990
|
0.75
|
|
117
|
Antidepressant monoamine oxidase inhibitors enhance serotonin but not norepinephrine neurotransmission.
|
Psychopharmacol Ser
|
1987
|
0.75
|
|
118
|
The benzodiazepine receptor inverse agonist DMCM decreases serotonergic transmission in rat hippocampus: an in vivo electrophysiological study.
|
Synapse
|
1990
|
0.75
|
|
119
|
Potentiation of 5-HT neurotransmission by short-term lithium: in vivo electrophysiological studies.
|
Clin Neuropharmacol
|
1992
|
0.75
|
|
120
|
Effect of the beta-adrenoceptor agonist flerobuterol on serotonin synthesis in the rat brain.
|
Biochem Pharmacol
|
2000
|
0.75
|
|
121
|
Effects of long-term alpha-2 adrenergic antagonists and electroconvulsive treatments on the alpha-2 adrenoceptors modulating serotonin neurotransmission.
|
J Pharmacol Exp Ther
|
1994
|
0.75
|
|
122
|
Plasma catecholamines at rest and exercise in subjects with high- and low-trait anxiety.
|
Psychosom Med
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1986
|
0.75
|
|
123
|
Reproducibility of plasma catecholamine concentrations at rest and during exercise in man.
|
Eur J Appl Physiol Occup Physiol
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1986
|
0.75
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|
124
|
Flerobuterol, a beta-adrenoceptor agonist, enhances serotonergic neurotransmission: an electrophysiological study in the rat brain.
|
Psychopharmacology (Berl)
|
1991
|
0.75
|
|
125
|
Branchial Na(+)K(+)ATPase activity in brook charr (Salvelinus fontinalis): effect of gonadal development in hypo- and hyperosmotic environments.
|
J Exp Zool
|
2000
|
0.75
|
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126
|
Discrepancies between the in vitro and in vivo 5-HT and norepinephrine re-uptake blocking properties of venlafaxine.
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Ann N Y Acad Sci
|
1998
|
0.75
|