PubRank

Manuela Neumann

Author PubWeight™ 144.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol 2007 8.10
2 Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann Neurol 2007 6.58
3 Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet 2010 5.52
4 TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis. Lancet Neurol 2008 5.33
5 TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am J Pathol 2007 5.02
6 Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathol 2009 4.73
7 Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathol 2008 4.73
8 Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies. Am J Pathol 2006 4.32
9 A harmonized classification system for FTLD-TDP pathology. Acta Neuropathol 2011 4.15
10 TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol 2010 3.92
11 ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import. EMBO J 2010 3.58
12 Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies. J Neuropathol Exp Neurol 2008 2.96
13 Clinical and pathological continuum of multisystem TDP-43 proteinopathies. Arch Neurol 2009 2.68
14 Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies. J Biol Chem 2009 2.60
15 FUS pathology in basophilic inclusion body disease. Acta Neuropathol 2009 2.52
16 Advances in understanding the molecular basis of frontotemporal dementia. Nat Rev Neurol 2012 2.48
17 Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Am J Pathol 2008 2.41
18 Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. EMBO J 2009 2.37
19 Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol 2005 2.36
20 FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. Acta Neuropathol 2010 2.30
21 hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations. Acta Neuropathol 2013 2.27
22 The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. Arch Neurol 2010 2.19
23 Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathol 2011 2.17
24 TDP-43 proteinopathy: the neuropathology underlying major forms of sporadic and familial frontotemporal lobar degeneration and motor neuron disease. Acta Neuropathol 2007 2.12
25 TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97. J Neurosci 2010 2.05
26 TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD. Acta Neuropathol 2008 2.02
27 Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes. EMBO Rep 2002 1.91
28 Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion. J Biol Chem 2007 1.87
29 Two German kindreds with familial amyotrophic lateral sclerosis due to TARDBP mutations. Arch Neurol 2008 1.78
30 Proteolytic processing of TAR DNA binding protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin. J Neurochem 2009 1.76
31 Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone. Hum Mol Genet 2010 1.64
32 Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations. Acta Neuropathol 2013 1.59
33 TDP-43 pathologic lesions and clinical phenotype in frontotemporal lobar degeneration with ubiquitin-positive inclusions. Arch Neurol 2007 1.57
34 Clinical, genetic, and pathologic characteristics of patients with frontotemporal dementia and progranulin mutations. Arch Neurol 2007 1.45
35 Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS. EMBO J 2012 1.45
36 Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43). J Biol Chem 2012 1.43
37 Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43. J Biol Chem 2014 1.37
38 Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy. Am J Pathol 2005 1.36
39 Microglial activation mediates neurodegeneration related to oligodendroglial alpha-synucleinopathy: implications for multiple system atrophy. Mov Disord 2007 1.35
40 The neuropathology associated with repeat expansions in the C9ORF72 gene. Acta Neuropathol 2013 1.35
41 PART is part of Alzheimer disease. Acta Neuropathol 2015 1.31
42 Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype. Neurobiol Aging 2012 1.30
43 TDP-43 in cerebrospinal fluid of patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Arch Neurol 2008 1.28
44 Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. J Neurosci 2008 1.28
45 Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions. J Neurol 2008 1.28
46 Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice. Neurobiol Aging 2006 1.26
47 Distinct pathological subtypes of FTLD-FUS. Acta Neuropathol 2010 1.26
48 An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathol 2006 1.24
49 A mutation affecting the sodium/proton exchanger, SLC9A6, causes mental retardation with tau deposition. Brain 2010 1.20
50 Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling. J Neurosci 2011 1.20
51 Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: two distinct patterns correlating with disease severity and mutation. Acta Neuropathol 2011 1.19
52 PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology. Brain 2014 1.16
53 Creutzfeldt-Jakob disease in a patient with an R208H mutation of the prion protein gene (PRNP) and a 17-kDa prion protein fragment. Acta Neuropathol 2005 1.09
54 TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathol 2014 1.08
55 Tau protein, Abeta42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies. Dement Geriatr Cogn Disord 2005 1.03
56 Aβ seeds resist inactivation by formaldehyde. Acta Neuropathol 2014 1.03
57 TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system. Acta Neuropathol 2007 1.02
58 Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Ann Neurol 2003 1.02
59 FET proteins in frontotemporal dementia and amyotrophic lateral sclerosis. Brain Res 2011 1.00
60 Mechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effects. Acta Neuropathol 2012 0.99
61 Transactive response DNA-binding protein 43 burden in familial Alzheimer disease and Down syndrome. Arch Neurol 2009 0.96
62 The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide. Rapid Commun Mass Spectrom 2003 0.95
63 The 20S proteasome isolated from Alzheimer's disease brain shows post-translational modifications but unchanged proteolytic activity. J Neurochem 2007 0.94
64 Structure/function of alpha-synuclein in health and disease: rational development of animal models for Parkinson's and related diseases. J Neurochem 2002 0.90
65 Cerebral gene expression profiles in sporadic Creutzfeldt-Jakob disease. Ann Neurol 2005 0.89
66 Novel types of frontotemporal lobar degeneration: beyond tau and TDP-43. J Mol Neurosci 2011 0.87
67 Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene. Mol Neurodegener 2014 0.84
68 FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy. PLoS One 2013 0.84
69 Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases. Neuron 2016 0.80
70 Differential sialylation of serpin A1 in the early diagnosis of Parkinson's disease dementia. PLoS One 2012 0.79
71 Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium. J Neural Transm (Vienna) 2014 0.78
72 Malignant optic glioma - the spectrum of disease in a case series. Graefes Arch Clin Exp Ophthalmol 2015 0.78
73 Mutations in protein N-arginine methyltransferases are not the cause of FTLD-FUS. Neurobiol Aging 2013 0.77
74 Body mass index is associated with biological CSF markers of core brain pathology in Alzheimer's disease. Neurobiol Aging 2012 0.77
75 Novel PS1 mutation in a Bavarian kindred with familial Alzheimer disease. Alzheimer Dis Assoc Disord 2004 0.75
76 Erratum to: Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium. J Neural Transm (Vienna) 2015 0.75