Paul T Wilder

Author PubWeight™ 18.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1. Am J Physiol Cell Physiol 2011 1.55
2 Inhibiting S100B restores p53 levels in primary malignant melanoma cancer cells. J Biol Chem 2004 1.38
3 Calcium-binding properties of wild-type and EF-hand mutants of S100B in the presence and absence of a peptide derived from the C-terminal negative regulatory domain of p53. Biochemistry 2005 1.14
4 Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA. Biochemistry 2008 1.10
5 Divalent metal ion complexes of S100B in the absence and presence of pentamidine. J Mol Biol 2008 1.09
6 The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak. Mol Cancer 2013 1.04
7 The calcium-binding protein S100B down-regulates p53 and apoptosis in malignant melanoma. J Biol Chem 2010 1.04
8 The effects of CapZ peptide (TRTK-12) binding to S100B-Ca2+ as examined by NMR and X-ray crystallography. J Mol Biol 2010 1.01
9 Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors. Org Biomol Chem 2012 0.98
10 Solution structure of S100A1 bound to the CapZ peptide (TRTK12). J Mol Biol 2009 0.97
11 Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography. Biochemistry 2009 0.89
12 Covalent small molecule inhibitors of Ca(2+)-bound S100B. Biochemistry 2014 0.88
13 Amphipathic α-helix mimetics based on a 1,2-diphenylacetylene scaffold. Org Lett 2013 0.87
14 Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B. ACS Med Chem Lett 2012 0.83
15 Complex formation between S100B protein and the p90 ribosomal S6 kinase (RSK) in malignant melanoma is calcium-dependent and inhibits extracellular signal-regulated kinase (ERK)-mediated phosphorylation of RSK. J Biol Chem 2014 0.83
16 The calcium-dependent interaction between S100B and the mitochondrial AAA ATPase ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A. Mol Cell Biol 2010 0.82
17 The effect of processing and cryopreservation on nucleated umbilical cord blood cells. J Perinat Med 2004 0.82
18 Structure of the S100A4/myosin-IIA complex. BMC Struct Biol 2013 0.80
19 Simultaneous inhibition of key growth pathways in melanoma cells and tumor regression by a designed bidentate constrained helical peptide. Biopolymers 2014 0.76