Published in Bioinformatics on April 14, 2008
Integrative multicellular biological modeling: a case study of 3D epidermal development using GPU algorithms. BMC Syst Biol (2010) 1.11
Agent-based modeling of endotoxin-induced acute inflammatory response in human blood leukocytes. PLoS One (2010) 1.08
Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system. PLoS One (2010) 0.98
Strategies for efficient numerical implementation of hybrid multi-scale agent-based models to describe biological systems. Cell Mol Bioeng (2015) 0.97
Cellular and population plasticity of helper CD4(+) T cell responses. Front Physiol (2013) 0.96
Competition for antigen between Th1 and Th2 responses determines the timing of the immune response switch during Mycobaterium avium subspecies paratuberulosis infection in ruminants. PLoS Comput Biol (2014) 0.91
Intraindividual long term stability and response corridors of cytokines in healthy volunteers detected by a standardized whole-blood culture system for bed-side application. BMC Med Res Methodol (2012) 0.89
Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation. PLoS Comput Biol (2010) 0.87
Computational modeling of heterogeneity and function of CD4+ T cells. Front Cell Dev Biol (2014) 0.86
Interleukin 12 receptor deficiency in a child with recurrent bronchopneumonia and very high IgE levels. Ital J Pediatr (2012) 0.82
Modeling biology spanning different scales: an open challenge. Biomed Res Int (2014) 0.81
Development of immune-specific interaction potentials and their application in the multi-agent-system VaccImm. PLoS One (2011) 0.80
How the interval between prime and boost injection affects the immune response in a computational model of the immune system. Comput Math Methods Med (2012) 0.80
Gradient descent optimization in gene regulatory pathways. PLoS One (2010) 0.79
Identification of core T cell network based on immunome interactome. BMC Syst Biol (2014) 0.77
Introduction of a Framework for Dynamic Knowledge Representation of the Control Structure of Transplant Immunology: Employing the Power of Abstraction with a Solid Organ Transplant Agent-Based Model. Front Immunol (2015) 0.77
Agent-based model of fecal microbial transplant effect on bile acid metabolism on suppressing Clostridium difficile infection: an example of agent-based modeling of intestinal bacterial infection. J Pharmacokinet Pharmacodyn (2014) 0.77
The onset of type 2 diabetes: proposal for a multi-scale model. JMIR Res Protoc (2013) 0.76
IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8(+) T cell-APC: a multiscale modeling study. BMC Syst Biol (2016) 0.75
ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization. Brief Bioinform (2009) 1.19
ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale. Philos Trans A Math Phys Eng Sci (2010) 1.16
Vaccine protocols optimization: in silico experiences. Biotechnol Adv (2009) 1.04
Modeling lymphocyte homing and encounters in lymph nodes. BMC Bioinformatics (2009) 1.03
Modelling vaccination schedules for a cancer immunoprevention vaccine. Immunome Res (2005) 0.99
Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system. PLoS One (2010) 0.98
Keratoconus staging: a computer-assisted ultrabiomicroscopic method compared with videokeratographic analysis. Cornea (2004) 0.96
Immune control of HIV-1 infection after therapy interruption: immediate versus deferred antiretroviral therapy. BMC Infect Dis (2009) 0.93
Timely HAART initiation may pave the way for a better viral control. BMC Infect Dis (2011) 0.91
A one-mutation mathematical model can explain the age incidence of acute myeloid leukemia with mutated nucleophosmin (NPM1). Haematologica (2008) 0.89
Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation. PLoS Comput Biol (2010) 0.87
ProtNet: a tool for stochastic simulations of protein interaction networks dynamics. BMC Bioinformatics (2007) 0.82
Plasma HIV RNA decline and emergence of drug resistance mutations among patients with multiple virologic failures receiving resistance testing-guided HAART. AIDS Res Hum Retroviruses (2008) 0.80
Development of immune-specific interaction potentials and their application in the multi-agent-system VaccImm. PLoS One (2011) 0.80
Immune system simulation online. Bioinformatics (2011) 0.79
Immunological network signatures of cancer progression and survival. BMC Med Genomics (2011) 0.78
The hierarchical organization of natural protein interaction networks confers self-organization properties on pseudocells. BMC Syst Biol (2015) 0.78
Determination of the optimal therapeutic protocols in cancer immunotherapy. Math Biosci (2007) 0.77
VaccImm: simulating peptide vaccination in cancer therapy. BMC Bioinformatics (2013) 0.77
A model of ischemia-induced neuroblast activation in the adult subventricular zone. PLoS One (2009) 0.77
HIV reservoirs and immune surveillance evasion cause the failure of structured treatment interruptions: a computational study. PLoS One (2012) 0.75
Identifying correlations between chromosomal proximity of genes and distance of their products in protein-protein interaction networks of yeast. PLoS One (2013) 0.75
Community effort endorsing multiscale modelling, multiscale data science and multiscale computing for systems medicine. Brief Bioinform (2017) 0.75
Stability and phase transitions in a mathematical model of Duchenne muscular dystrophy. J Theor Biol (2009) 0.75
Evaluation of HIV-1 and CD4+ T cell dynamic parameters in patients treated with genotypic resistance testing-guided HAART. Curr HIV Res (2008) 0.75
Metabolic disorders: how can systems modelling help? Lancet Diabetes Endocrinol (2016) 0.75