Higher doses of lenalidomide are associated with unacceptable toxicity including life-threatening tumor flare in patients with chronic lymphocytic leukemia.

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Published in J Clin Oncol on April 21, 2008

Authors

Leslie A Andritsos1, Amy J Johnson, Gerard Lozanski, William Blum, Cheryl Kefauver, Farrukh Awan, Lisa L Smith, Rosa Lapalombella, Sarah E May, Chelsey A Raymond, Da-Sheng Wang, Robert D Knight, Amy S Ruppert, Amy Lehman, David Jarjoura, Ching-Shih Chen, John C Byrd

Author Affiliations

1: Division of Hematology-Oncology, Department of Medicine, The Ohio State University, Columbus, OH, USA.

Associated clinical trials:

Phase II Protocol for CLL With Fludarabine and Cyclophosphamide With Rituximab (FCR) Plus Lenalidomide (FCR) | NCT01723839

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