Published in Lab Invest on April 21, 2008
Mast cells contribute to scar formation during fetal wound healing. J Invest Dermatol (2011) 1.79
Cancer-associated fibroblasts drive the progression of metastasis through both paracrine and mechanical pressure on cancer tissue. Mol Cancer Res (2012) 1.73
Vascular Endothelial Growth Factor and Angiogenesis in the Regulation of Cutaneous Wound Repair. Adv Wound Care (New Rochelle) (2014) 1.11
Risk of scar in the comparison of age-related macular degeneration treatments trials. Ophthalmology (2013) 1.07
Real-time analysis of the kinetics of angiogenesis and vascular permeability in an animal model of wound healing. Burns (2009) 0.99
Cellular and Molecular Characteristics of Scarless versus Fibrotic Wound Healing. Dermatol Res Pract (2010) 0.97
A review of fetal scarless healing. ISRN Dermatol (2012) 0.96
Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 2: role of growth factors in normal and pathological wound healing: therapeutic potential and methods of delivery. Adv Skin Wound Care (2012) 0.95
The effect of vascular endothelial growth factor in the progression of bladder cancer and diabetic retinopathy. Int J Clin Exp Med (2013) 0.94
Apoptosis and angiogenesis: an evolving mechanism for fibrosis. FASEB J (2013) 0.93
Subconjunctival bevacizumab as an adjunct to trabeculectomy in eyes with refractory glaucoma: a case series. Korean J Ophthalmol (2010) 0.91
Dual growth factor releasing multi-functional nanofibers for wound healing. Acta Biomater (2013) 0.90
Pharmacological blockade of adenosine A2A receptors diminishes scarring. FASEB J (2012) 0.89
Complex roles for VEGF in dermal wound healing. J Invest Dermatol (2011) 0.88
Sprouty2 downregulates angiogenesis during mouse skin wound healing. Am J Physiol Heart Circ Physiol (2010) 0.87
Angiogenesis in glaucoma filtration surgery and neovascular glaucoma: A review. Surv Ophthalmol (2015) 0.87
Encapsulation of ePTFE in prevascularized collagen leads to peri-implant vascularization with reduced inflammation. J Biomed Mater Res A (2010) 0.84
The alarmin HMGB-1 influences healing outcomes in fetal skin wounds. Wound Repair Regen (2013) 0.83
Wound healing in development. Birth Defects Res C Embryo Today (2012) 0.83
Site-Specific Phosphorylation of VEGFR2 Is Mediated by Receptor Trafficking: Insights from a Computational Model. PLoS Comput Biol (2015) 0.83
Inhibition of placental growth factor improves surgical outcome of glaucoma surgery. J Cell Mol Med (2013) 0.82
Anti-VEGF Agents and Glaucoma Filtering Surgery. J Ophthalmic Vis Res (2013) 0.82
Improving patient outcomes following glaucoma surgery: state of the art and future perspectives. Clin Ophthalmol (2014) 0.82
Persistent inflammation and angiogenesis during wound healing in K14-directed Hoxb13 transgenic mice. J Invest Dermatol (2009) 0.82
New Uses of AbobotulinumtoxinA in Aesthetics. Aesthet Surg J (2017) 0.81
Tissue engineering and regenerative repair in wound healing. Ann Biomed Eng (2014) 0.80
Reduction of conjunctival fibrosis after trabeculectomy using topical α-lipoic acid in rabbit eyes. J Glaucoma (2014) 0.80
Mechanoregulation of Angiogenesis in Wound Healing. Adv Wound Care (New Rochelle) (2014) 0.80
Beta-Adrenoceptor Activation Reduces Both Dermal Microvascular Endothelial Cell Migration via a cAMP-Dependent Mechanism and Wound Angiogenesis. J Cell Physiol (2015) 0.79
microRNA-200b as a Switch for Inducible Adult Angiogenesis. Antioxid Redox Signal (2015) 0.78
The Importance of Mast Cells in Dermal Scarring. Adv Wound Care (New Rochelle) (2014) 0.78
Post-trabeculectomy topical bevacizumab preventing bleb failure: a preliminary study. J Ocul Biol Dis Infor (2013) 0.77
Developing novel anti-fibrotic therapeutics to modulate post-surgical wound healing in glaucoma: big potential for small molecules. Expert Rev Ophthalmol (2015) 0.77
β2-adrenoceptor activation modulates skin wound healing processes to reduce scarring. J Invest Dermatol (2014) 0.77
Methodologies in creating skin substitutes. Cell Mol Life Sci (2016) 0.76
The Effects of Bevacizumab in Augmenting Trabeculectomy for Glaucoma: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Medicine (Baltimore) (2016) 0.75
Wound Healing Activity of Extracts and Formulations of Aloe vera, Henna, Adiantum capillus-veneris, and Myrrh on Mouse Dermal Fibroblast Cells. Int J Prev Med (2017) 0.75
Safety of bevacizumab on extraocular muscle in a rabbit model. Korean J Ophthalmol (2012) 0.75
Anti-Vascular Endothelial Growth Factor (Bevacizumab) Therapy Reduces Hypertrophic Scar Formation in a Rabbit Ear Wounding Model. Arch Plast Surg (2016) 0.75
Intravitreal Injection of Bevacizumab in Primary Vitrectomy to Decrease the Rate of Retinal Redetachment: A Randomized Pilot Study. J Ophthalmic Vis Res (2016) 0.75
The efficiency of subconjunctival bevacizumab in refractory glaucoma - case report. J Med Life (2015) 0.75
Does topical bevacizumab prevent postoperative recurrence after pterygium surgery with conjunctival autografting? Int J Ophthalmol (2014) 0.75
Anti-Angiogenic Drugs: Involvement in Cutaneous Side Effects and Wound-Healing Complication. Adv Wound Care (New Rochelle) (2014) 0.75
Wound Healing Modulation in Glaucoma Filtration Surgery- Conventional Practices and New Perspectives: Antivascular Endothelial Growth Factor and Novel Agents (Part II). J Curr Glaucoma Pract (2014) 0.75
A hypoxia response element in the Vegfa promoter is required for basal Vegfa expression in skin and for optimal granulation tissue formation during wound healing in mice. PLoS One (2017) 0.75
Effects of bevacizumab loaded PEG-PCL-PEG hydrogel intracameral application on intraocular pressure after glaucoma filtration surgery. J Mater Sci Mater Med (2015) 0.75
The biology of VEGF and its receptors. Nat Med (2003) 32.13
Cutaneous wound healing. N Engl J Med (1999) 19.12
Vascular endothelial growth factor is a secreted angiogenic mitogen. Science (1989) 16.71
Wound healing--aiming for perfect skin regeneration. Science (1997) 16.08
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science (1983) 15.43
Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci U S A (1986) 12.14
Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science (1992) 7.92
Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest (1989) 5.71
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood (1996) 5.31
Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing. J Exp Med (1992) 4.39
Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor. Nature (1989) 3.80
Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci U S A (1986) 3.42
Topical vascular endothelial growth factor accelerates diabetic wound healing through increased angiogenesis and by mobilizing and recruiting bone marrow-derived cells. Am J Pathol (2004) 3.13
Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing. Am J Pathol (1998) 3.05
Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells. Curr Biol (2003) 2.87
Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. Hepatology (2002) 2.38
VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins. FASEB J (2004) 2.27
Control of hair growth and follicle size by VEGF-mediated angiogenesis. J Clin Invest (2001) 2.04
The extracellular matrix of lip wounds in fetal, neonatal and adult mice. Development (1991) 1.90
Immunohistochemical localization of growth factors in fetal wound healing. Dev Biol (1991) 1.90
Treatment variables affecting facial growth in complete unilateral cleft lip and palate. Cleft Palate J (1987) 1.78
Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma. Am J Pathol (2004) 1.77
Impaired wound repair and delayed angiogenesis in aged mice. Lab Invest (1999) 1.67
Vascular endothelial growth factor and receptor interaction is a prerequisite for murine hepatic fibrogenesis. Gut (2003) 1.60
Hypertrophic scars, keloids, and contractures. The cellular and molecular basis for therapy. Surg Clin North Am (1997) 1.56
Fetal response to injury in the rabbit. J Pediatr Surg (1987) 1.54
Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor. J Am Acad Dermatol (2004) 1.52
Transforming growth factor beta (TGF-beta) induces fibrosis in a fetal wound model. J Pediatr Surg (1988) 1.51
Diminished interleukin 6 (IL-6) production during scarless human fetal wound repair. Cytokine (2000) 1.48
Diminished interleukin-8 (IL-8) production in the fetal wound healing response. J Surg Res (1998) 1.48
Fetal wound repair results in scar formation in interleukin-10-deficient mice in a syngeneic murine model of scarless fetal wound repair. J Pediatr Surg (2000) 1.47
PGE2 and angiogenesis. Proc Soc Exp Biol Med (1983) 1.42
Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse. Blood (2003) 1.31
Intrauterine wound healing in a 20 week human fetus. Virchows Arch A Pathol Anat Histol (1979) 1.30
Deletion of neuropeptide Y (NPY) 2 receptor in mice results in blockage of NPY-induced angiogenesis and delayed wound healing. Proc Natl Acad Sci U S A (2003) 1.28
Ontogeny of the skin and the transition from scar-free to scarring phenotype during wound healing in the pouch young of a marsupial, Monodelphis domestica. Dev Biol (1995) 1.28
Endogenous inflammatory response to dermal wound healing in the fetal and adult mouse. Dev Dyn (1998) 1.27
Adenovirus-mediated VEGF(165) gene transfer enhances wound healing by promoting angiogenesis in CD1 diabetic mice. Gene Ther (2002) 1.26
The angiogenesis inhibitor endostatin impairs blood vessel maturation during wound healing. FASEB J (2000) 1.24
Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation. Cancer Res (2004) 1.23
Impairment of skin wound healing in beta-1,4-galactosyltransferase-deficient mice with reduced leukocyte recruitment. Am J Pathol (2004) 1.21
Adeno-associated viral vector-mediated human vascular endothelial growth factor gene transfer stimulates angiogenesis and wound healing in the genetically diabetic mouse. Diabetologia (2003) 1.21
The impact of cyclooxygenase-2 mediated inflammation on scarless fetal wound healing. Am J Pathol (2004) 1.20
Diminished induction of skin fibrosis in mice with MCP-1 deficiency. J Invest Dermatol (2006) 1.18
Reduction of scar formation in full-thickness wounds with topical celecoxib treatment. Wound Repair Regen (2003) 1.18
Dexamethasone induction of keloid regression through effective suppression of VEGF expression and keloid fibroblast proliferation. J Invest Dermatol (2006) 1.14
The effects of ZD6474, an inhibitor of VEGF signaling, on cutaneous wound healing in mice. J Surg Res (2005) 1.12
Ontogenetic transition of wound healing pattern in rat skin occurring at the fetal stage. Development (1990) 1.12
Alterations in the immunohistochemical distribution patterns of vascular endothelial growth factor receptors Flk1 and Flt1 in bleomycin-induced rat lung fibrosis. Virchows Arch (1999) 1.05
Fetal wound healing. Front Biosci (2003) 1.05
Effects of angiotensin II receptor signaling during skin wound healing. Am J Pathol (2004) 1.04
Vascular endothelial growth factor VEGF189 induces human neutrophil chemotaxis in extravascular tissue via an autocrine amplification mechanism. Lab Invest (2004) 1.03
Recombinant AAV vector encoding human VEGF165 enhances wound healing. Gene Ther (2002) 1.02
In vivo gene delivery of Ad-VEGF121 to full-thickness wounds in aged pigs results in high levels of VEGF expression but not in accelerated healing. Wound Repair Regen (2005) 0.95
Platelet-derived growth factor induces fetal wound fibrosis. J Pediatr Surg (1994) 0.95
Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis. Gene Ther (2004) 0.95
Increased angiogenesis and expression of vascular endothelial growth factor during scarless repair. Plast Reconstr Surg (2005) 0.94
Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts. Am J Physiol Cell Physiol (2003) 0.93
Role of alpha(v) integrins and angiogenesis during wound repair. Wound Repair Regen (1999) 0.93
Overhydroxylation of lysyl residues is the initial step for altered collagen cross-links and fibril architecture in fibrotic skin. J Invest Dermatol (1999) 0.92
The angiogenesis inhibitor vasostatin does not impair wound healing at tumor-inhibiting doses. J Invest Dermatol (2001) 0.91
Biology of fetal repair: the presence of bacteria in fetal wounds induces an adult-like healing response. J Pediatr Surg (1993) 0.91
Liposome-mediated transfer of vascular endothelial growth factor cDNA augments survival of random-pattern skin flaps in the rat. Wound Repair Regen (2004) 0.86
Locally administered vascular endothelial growth factor cDNA increases survival of ischemic experimental skin flaps. Plast Reconstr Surg (1998) 0.84
Vascular endothelial growth factor-mediated angiogenesis inhibition and postoperative wound healing in rats. J Surg Res (2002) 0.84
Acute inflammation in foetal and adult sheep: the response to subcutaneous injection of turpentine and carrageenan. Br J Plast Surg (1994) 0.83
AdVEGF165 gene transfer increases survival in overdimensioned skin flaps. J Gene Med (2005) 0.83
Monodelphis domesticus: a model for early developmental wound healing. Ann Plast Surg (1991) 0.83
Phase I study of the antineovascularization drug CM101. Clin Cancer Res (1997) 0.80
A new in vivo model for the study of fetal wound healing. Ann Plast Surg (1997) 0.80
CM101 stimulates cutaneous wound healing through an anti-angiogenic mechanism. Angiogenesis (2001) 0.80
The hairless mouse in skin research. J Dermatol Sci (2008) 1.95
Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma. Am J Pathol (2004) 1.77
Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A. J Invest Dermatol (2008) 1.64
UV light B-mediated inhibition of skin catalase activity promotes Gr-1+ CD11b+ myeloid cell expansion. J Invest Dermatol (2011) 1.61
Gender differences in UVB-induced skin carcinogenesis, inflammation, and DNA damage. Cancer Res (2007) 1.57
Chronic stress and susceptibility to skin cancer. J Natl Cancer Inst (2005) 1.41
Inhibition of cutaneous ultraviolet light B-mediated inflammation and tumor formation with topical celecoxib treatment. Mol Carcinog (2003) 1.39
The impact of cyclooxygenase-2 mediated inflammation on scarless fetal wound healing. Am J Pathol (2004) 1.20
Reduction of scar formation in full-thickness wounds with topical celecoxib treatment. Wound Repair Regen (2003) 1.18
Site-specific production of TGF-beta in oral mucosal and cutaneous wounds. Wound Repair Regen (2007) 1.17
Importance of the EP(1) receptor in cutaneous UVB-induced inflammation and tumor development. J Invest Dermatol (2006) 1.12
Mast cells modulate the inflammatory but not the proliferative response in healing wounds. Wound Repair Regen (2003) 1.12
Acute ethanol exposure impairs angiogenesis and the proliferative phase of wound healing. Am J Physiol Heart Circ Physiol (2005) 1.11
Platelet-rich fibrin matrix improves wound angiogenesis via inducing endothelial cell proliferation. Wound Repair Regen (2011) 1.03
Processing and treatment of corncob bedding affects cage-change frequency for C57BL/6 mice. J Am Assoc Lab Anim Sci (2012) 1.03
Elevated monocyte chemoattractant protein-1 levels following thermal injury precede monocyte recruitment to the wound site and are controlled, in part, by tumor necrosis factor-alpha. Wound Repair Regen (2003) 0.99
Accelerated transferrin degradation in HFE-deficient mice is associated with increased transferrin saturation. J Nutr (2006) 0.95
Preventative topical diclofenac treatment differentially decreases tumor burden in male and female Skh-1 mice in a model of UVB-induced cutaneous squamous cell carcinoma. Carcinogenesis (2012) 0.93
Chemotherapeutic efficacy of topical celecoxib in a murine model of ultraviolet light B-induced skin cancer. Mol Carcinog (2003) 0.92
Treatment with 5-fluorouracil and celecoxib displays synergistic regression of ultraviolet light B-induced skin tumors. J Invest Dermatol (2004) 0.92
Topical treatment with black raspberry extract reduces cutaneous UVB-induced carcinogenesis and inflammation. Cancer Prev Res (Phila) (2009) 0.91
The effect of MCP-1 depletion on chemokine and chemokine-related gene expression: evidence for a complex network in acute inflammation. Cytokine (2005) 0.90
Effects of UVB on E prostanoid receptor expression in murine skin. J Invest Dermatol (2006) 0.90
Hydrogen peroxide disrupts scarless fetal wound repair. Wound Repair Regen (2005) 0.89
Clinically relevant immunosuppressants influence UVB-induced tumor size through effects on inflammation and angiogenesis. Am J Transplant (2007) 0.89
Depletion of CD4+ cells exacerbates the cutaneous response to acute and chronic UVB exposure. J Invest Dermatol (2007) 0.89
Short-term stress enhances cellular immunity and increases early resistance to squamous cell carcinoma. Brain Behav Immun (2009) 0.87
Beta 2-microglobulin deficient mice catabolize IgG more rapidly than FcRn- alpha-chain deficient mice. Exp Biol Med (Maywood) (2008) 0.87
Tocotrienol vitamin E protects against preclinical canine ischemic stroke by inducing arteriogenesis. J Cereb Blood Flow Metab (2011) 0.86
Differential effects of topical vitamin E and C E Ferulic® treatments on ultraviolet light B-induced cutaneous tumor development in Skh-1 mice. PLoS One (2013) 0.85
Topical treatment with OGG1 enzyme affects UVB-induced skin carcinogenesis. Photochem Photobiol (2007) 0.85
High-anxious individuals show increased chronic stress burden, decreased protective immunity, and increased cancer progression in a mouse model of squamous cell carcinoma. PLoS One (2012) 0.84
An endovascular canine middle cerebral artery occlusion model for the study of leptomeningeal collateral recruitment. Invest Radiol (2011) 0.83
Effectiveness of shoe covers for bioexclusion within an animal facility. J Am Assoc Lab Anim Sci (2012) 0.81
Micro-field evoked potentials recorded from the porcine sub-dural cortical surface utilizing a microelectrode array. J Neurosci Methods (2007) 0.80
Depletion of CD8+ or CD4+ lymphocytes enhances susceptibility to transplantable ultraviolet radiation-induced skin tumours. Anticancer Res (2005) 0.80
Isothiocyanate metabolism, distribution, and interconversion in mice following consumption of thermally processed broccoli sprouts or purified sulforaphane. Mol Nutr Food Res (2014) 0.79
Celecoxib reduces the effects of acute and chronic UVB exposure in mice treated with therapeutically relevant immunosuppressive drugs. Int J Cancer (2010) 0.79
Exenatide pretreatment improved graft function in nonhuman primate islet recipients compared to treatment after transplant only. J Transplant (2012) 0.79
Ribonucleotide reductase inhibitors reduce atherosclerosis in a double-injury rabbit model. Comp Med (2009) 0.78
Chromosomal aberrations in UVB-induced tumors of immunosuppressed mice. Genes Chromosomes Cancer (2009) 0.77
Ultraviolet light exposure stimulates HMGB1 release by keratinocytes. Arch Dermatol Res (2013) 0.77
Possible cross-regulation of the E prostanoid receptors. Mol Carcinog (2007) 0.77
Extended UVB Exposures Alter Tumorigenesis and Treatment Efficacy in a Murine Model of Cutaneous Squamous Cell Carcinoma. J Skin Cancer (2013) 0.76
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis. Eur J Cancer (2007) 0.75