Published in Arthritis Rheum on May 01, 2008
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Hierarchy of risk of childhood-onset rheumatoid arthritis conferred by HLA-DRB1 alleles encoding the shared epitope. Arthritis Rheum (2012) 0.98
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A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination. Arthritis Rheum (2006) 9.52
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature (1993) 8.75
Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. N Engl J Med (1978) 7.97
The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis. Ann Intern Med (1992) 3.36
New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility. Arthritis Rheum (2005) 2.48
The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture. Arthritis Rheum (2008) 2.13
The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept. Arthritis Rheum (2004) 1.55
Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67-74 of the HLA-DRB1 molecule. Arthritis Rheum (2002) 1.41
Influence of shared epitope-negative HLA-DRB1 alleles on genetic susceptibility to rheumatoid arthritis. Arthritis Rheum (2001) 1.30
HLA-DRB1 alleles encoding an aspartic acid at position 70 protect against development of rheumatoid arthritis. J Rheumatol (2001) 1.25
Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis. Arthritis Res Ther (2006) 1.22
The relationship between HLA-DRB1 alleles and disease subsets of rheumatoid arthritis in Japanese. Br J Rheumatol (1997) 1.17
The shared epitope hypothesis in rheumatoid arthritis: evaluation of alternative classification criteria in a large UK Caucasian cohort. Arthritis Rheum (2008) 1.16
HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments. Ann Rheum Dis (1998) 1.14
Rheumatoid arthritis may be primarily associated with HLA-DR4 molecules sharing a particular sequence at residues 67-74. Tissue Antigens (1990) 1.01
Protective HLA-DR phenotypes in rheumatoid arthritis. J Rheumatol (1989) 0.90
Reshaping Cinderella's slipper: the shared epitope hypothesis. Arthritis Res Ther (2006) 0.88
2012 update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken) (2012) 12.07
American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis. Arthritis Rheum (2008) 9.94
A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: the treatment of Early Aggressive Rheumatoid Arthritis Trial. Arthritis Rheum (2012) 4.01
Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families. Arthritis Rheum (2003) 3.73
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. Nat Genet (2009) 3.36
A comparison of patient characteristics and outcomes in selected European and U.S. rheumatoid arthritis registries. Semin Arthritis Rheum (2010) 2.88
The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture. Arthritis Rheum (2008) 2.13
Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy. Arthritis Rheum (2010) 2.08
Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study. Radiology (2009) 1.95
Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis. J Clin Invest (2011) 1.63
The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept. Arthritis Rheum (2004) 1.55
Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis. PLoS Genet (2013) 1.54
Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12. Am J Hum Genet (2012) 1.46
Comparison of the disease activity score using erythrocyte sedimentation rate and C-reactive protein in African Americans with rheumatoid arthritis. J Rheumatol (2013) 1.45
Assessment of synovitis with contrast-enhanced MRI using a whole-joint semiquantitative scoring system in people with, or at high risk of, knee osteoarthritis: the MOST study. Ann Rheum Dis (2010) 1.35
Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans. Arthritis Rheum (2010) 1.34
Contribution of Vh gene replacement to the primary B cell repertoire. Immunity (2003) 1.32
Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritis. Arthritis Rheum (2006) 1.28
Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge. Nat Genet (2013) 1.21
Vitamin D status and its associations with disease activity and severity in African Americans with recent-onset rheumatoid arthritis. J Rheumatol (2009) 1.19
Changes in lipoproteins associated with methotrexate or combination therapy in early rheumatoid arthritis: results from the treatment of early rheumatoid arthritis trial. Arthritis Rheum (2013) 1.18
Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis. Ann Rheum Dis (2012) 1.10
Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction. Cell Stem Cell (2013) 1.10
Associations of cigarette smoking with rheumatoid arthritis in African Americans. Arthritis Rheum (2010) 1.09
Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study. Arthritis Res Ther (2010) 1.04
Prevalence of osteoporosis and osteopenia among African Americans with early rheumatoid arthritis: the impact of ethnic-specific normative data. J Natl Med Assoc (2005) 1.02
Validation of the methotrexate-first strategy in patients with early, poor-prognosis rheumatoid arthritis: results from a two-year randomized, double-blind trial. Arthritis Rheum (2013) 1.01
Radiographic severity of rheumatoid arthritis in African Americans: results from a multicenter observational study. Arthritis Care Res (Hoboken) (2010) 0.98
Recommendations for publication of genetic association studies in Arthritis & Rheumatism. Arthritis Rheum (2011) 0.96
Refining the association of MHC with multiple sclerosis in African Americans. Hum Mol Genet (2010) 0.96
Clinical response within 12 weeks as a predictor of future low disease activity in patients with early RA: results from the TEAR Trial. J Rheumatol (2013) 0.96
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Int J Epidemiol (2015) 0.93
Association of single-nucleotide polymorphisms in CCR6, TAGAP, and TNFAIP3 with rheumatoid arthritis in African Americans. Arthritis Rheum (2012) 0.90
Markers of treatment response to methotrexate in rheumatoid arthritis: where do we stand? Int J Rheumatol (2012) 0.90
Evidence for two phenotypes in the metabolism of methotrexate to 7-hydroxymethotrexate in patients with rheumatoid arthritis. Arthritis Rheum (2005) 0.88
A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis. Arthritis Rheum (2010) 0.87
Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans. Arthritis Rheum (2012) 0.87
Genetic markers of treatment response in rheumatoid arthritis. Arthritis Rheum (2004) 0.86
The role of B cells and autoantibodies in rheumatoid arthritis. Pathophysiology (2005) 0.85
Molecular mechanism of serial VH gene replacement. Ann N Y Acad Sci (2003) 0.85
Serum cotinine as a biomarker of tobacco exposure and the association with treatment response in early rheumatoid arthritis. Arthritis Care Res (Hoboken) (2012) 0.84
Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans. Ann Rheum Dis (2010) 0.84
Polyarteritis nodosa and microscopic polyangiitis: etiologic and diagnostic considerations. Curr Rheumatol Rep (2002) 0.83
Retraction: an African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans. PLoS Genet (2009) 0.83
Association of IL4R single-nucleotide polymorphisms with rheumatoid nodules in African Americans with rheumatoid arthritis. Arthritis Res Ther (2010) 0.83
Does gamma-aminobutyric acid (GABA) influence the development of chronic inflammation in rheumatoid arthritis? J Neuroinflammation (2008) 0.82
Inhibition of fucosylation reshapes inflammatory macrophages and suppresses type II collagen-induced arthritis. Arthritis Rheumatol (2014) 0.82
Gene expression patterns in peripheral blood cells associated with radiographic severity in African Americans with early rheumatoid arthritis. Rheumatol Int (2012) 0.82
HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: hierarchical classification systems, amino acid positions, and residues. Arthritis Rheumatol (2014) 0.82
Pharmacogenetics of etanercept in rheumatoid arthritis. Pharmacogenomics (2008) 0.82
Variable selection in logistic regression for detecting SNP-SNP interactions: the rheumatoid arthritis example. Eur J Hum Genet (2008) 0.81
V(D)J recombinatorial repertoire diversification during intraclonal pro-B to B-cell differentiation. Blood (2002) 0.81
Generalized bone loss as a predictor of three-year radiographic damage in African American patients with recent-onset rheumatoid arthritis. Arthritis Rheum (2010) 0.81
Genetic influences on rheumatoid arthritis in African Americans. Immunol Res (2002) 0.80
Sources and migration of plutonium in groundwater at the Savannah River site. Environ Sci Technol (2002) 0.80
Socioeconomic disparities in the health of african americans with rheumatoid arthritis from the southeastern United States. Arthritis Care Res (Hoboken) (2014) 0.79
Gene-body mass index interactions are associated with methotrexate toxicity in rheumatoid arthritis. Ann Rheum Dis (2013) 0.79
Measurement of erythrocyte methotrexate polyglutamate levels: ready for clinical use in rheumatoid arthritis? Curr Rheumatol Rep (2010) 0.78
Retracted An African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans. PLoS Genet (2009) 0.78
Complementary and alternative medicine use in African Americans with rheumatoid arthritis. Arthritis Care Res (Hoboken) (2014) 0.77
Clinical and genetic risk factors for pneumonia in systemic lupus erythematosus. Arthritis Rheum (2007) 0.77
Personalized medicine in rheumatoid arthritis: miles to go before we sleep. Arthritis Rheum (2011) 0.76
Ethnic-specific genetic analyses in rheumatoid arthritis: incremental gains but valuable contributions to the big picture. Arthritis Rheum (2013) 0.75
CASPASE-12 and rheumatoid arthritis in African-Americans. Immunogenetics (2014) 0.75
Expression of Interferon-γ Receptor Genes in Peripheral Blood Mononuclear Cells Is Associated With Rheumatoid Arthritis and Its Radiographic Severity in African Americans. Arthritis Rheumatol (2015) 0.75
Associations of alcohol use with radiographic disease progression in African Americans with recent-onset rheumatoid arthritis. J Rheumatol (2013) 0.75
Understanding Personalized Medicine in Rheumatoid Arthritis: A Clinician's Guide to the Future. Ther Adv Musculoskelet Dis (2009) 0.75
ANCA-associated vasculitis. Preface. Rheum Dis Clin North Am (2010) 0.75
Method comparison of a 25-hydroxy vitamin D enzyme immunoassay to liquid chromatography tandem mass spectroscopy. Clin Chem Lab Med (2012) 0.75
Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. Nat Commun (2016) 0.75
Update on pathogenic mechanisms of systemic necrotizing vasculitis. Curr Rheumatol Rep (2008) 0.75