Haruo Sugiyama

Author PubWeight™ 97.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression. Proc Natl Acad Sci U S A 2004 2.58
2 The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia. Blood 2002 2.25
3 CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia. Proc Natl Acad Sci U S A 2007 1.99
4 Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination. Proc Natl Acad Sci U S A 2010 1.84
5 Immunohistochemical detection of WT1 protein in a variety of cancer cells. Mod Pathol 2006 1.62
6 High expression of Wilms' tumor suppressor gene predicts poor prognosis in breast cancer patients. Clin Cancer Res 2002 1.49
7 Differences in blast immunophenotypes among disease types in myelodysplastic syndromes: a multicenter validation study. Leuk Res 2012 1.42
8 Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers. Int J Cancer 2002 1.32
9 AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1. Blood 2005 1.26
10 Wilms tumor gene peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis. Int J Hematol 2003 1.18
11 Phase II clinical trial of Wilms tumor 1 peptide vaccination for patients with recurrent glioblastoma multiforme. J Neurosurg 2008 1.16
12 Overexpression of the Wilms' tumor gene WT1 in colorectal adenocarcinoma. Cancer Sci 2003 1.15
13 Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes. Blood 2005 1.10
14 Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer WT1 peptide modified at HLA-A*2402-binding residues. Cancer Immunol Immunother 2002 1.08
15 Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2/M progression in the cell cycle. Int J Oncol 2009 1.08
16 WT1 peptide vaccine for the treatment of cancer. Curr Opin Immunol 2008 1.04
17 Wilms' tumor gene WT1-shRNA as a potent apoptosis-inducing agent for solid tumors. Int J Oncol 2008 1.04
18 Overexpression of the Wilms' tumor gene W T1 in primary astrocytic tumors. Cancer Sci 2004 1.02
19 Very low frequencies of human normal CD34+ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells. Br J Haematol 2002 1.02
20 Diffuse large B-cell lymphoma in the spinal epidural space: A study of the Osaka Lymphoma Study Group. Pathol Res Pract 2010 1.01
21 Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma. Cancer Sci 2004 1.01
22 Humoral immune responses against Wilms tumor gene WT1 product in patients with hematopoietic malignancies. Blood 2002 0.98
23 A phase I/II trial of a WT1 (Wilms' tumor gene) peptide vaccine in patients with solid malignancy: safety assessment based on the phase I data. Jpn J Clin Oncol 2006 0.98
24 Gemcitabine enhances Wilms' tumor gene WT1 expression and sensitizes human pancreatic cancer cells with WT1-specific T-cell-mediated antitumor immune response. Cancer Immunol Immunother 2011 0.96
25 Overexpression of the Wilms' tumor gene WT1 in primary thyroid cancer. Cancer Sci 2003 0.96
26 WT1 IgG antibody for early detection of nonsmall cell lung cancer and as its prognostic factor. Int J Cancer 2009 0.95
27 Wilms tumor gene (WT1) peptide-based cancer vaccine combined with gemcitabine for patients with advanced pancreatic cancer. J Immunother 2014 0.95
28 WT1 (Wilms' tumor 1) peptide immunotherapy for renal cell carcinoma. Microbiol Immunol 2007 0.95
29 CD166/activated leukocyte cell adhesion molecule is expressed on glioblastoma progenitor cells and involved in the regulation of tumor cell invasion. Neuro Oncol 2011 0.94
30 Overexpression of the Wilms' tumor gene WT1 in human bone and soft-tissue sarcomas. Cancer Sci 2003 0.94
31 Single-cell analysis of T-cell receptor repertoire of HTLV-1 Tax-specific cytotoxic T cells in allogeneic transplant recipients with adult T-cell leukemia/lymphoma. Cancer Res 2010 0.92
32 WT1 peptide cancer vaccine for patients with hematopoietic malignancies and solid cancers. ScientificWorldJournal 2007 0.91
33 Wilms' tumor gene WT1 17AA(-)/KTS(-) isoform induces morphological changes and promotes cell migration and invasion in vitro. Cancer Sci 2006 0.91
34 Epstein-barr virus in diffuse large B-Cell lymphoma in immunocompetent patients in Japan is as low as in Western Countries. J Med Virol 2011 0.91
35 Prognostic significance of BACH2 expression in diffuse large B-cell lymphoma: a study of the Osaka Lymphoma Study Group. J Clin Oncol 2005 0.90
36 WT1 peptide-based immunotherapy for patients with lung cancer: report of two cases. Microbiol Immunol 2004 0.90
37 CD48 as a novel molecular target for antibody therapy in multiple myeloma. Br J Haematol 2011 0.89
38 Wilms tumor gene WT1 peptide-based immunotherapy induced a minimal response in a patient with advanced therapy-resistant multiple myeloma. Int J Hematol 2007 0.89
39 Wilms' tumor 1 (WT1) peptide immunotherapy for gynecological malignancy. Anticancer Res 2009 0.88
40 Use of (11)C-methionine PET parametric response map for monitoring WT1 immunotherapy response in recurrent malignant glioma. J Neurosurg 2012 0.88
41 Prognostic significance of Wilms tumor gene (WT1) mRNA expression in soft tissue sarcoma. Cancer 2006 0.88
42 Correlation between promoter hypermethylation of GSTP1 and response to chemotherapy in diffuse large B cell lymphoma. Ann Hematol 2007 0.86
43 High frequencies of less differentiated and more proliferative WT1-specific CD8+ T cells in bone marrow in tumor-bearing patients: an important role of bone marrow as a secondary lymphoid organ. Cancer Sci 2009 0.86
44 Identification and characterization of a WT1 (Wilms Tumor Gene) protein-derived HLA-DRB1*0405-restricted 16-mer helper peptide that promotes the induction and activation of WT1-specific cytotoxic T lymphocytes. J Immunother 2007 0.85
45 Biased usage of BV gene families of T-cell receptors of WT1 (Wilms' tumor gene)-specific CD8+ T cells in patients with myeloid malignancies. Cancer Sci 2009 0.84
46 Overexpression of the Wilms' tumor gene WT1 in head and neck squamous cell carcinoma. Cancer Sci 2003 0.84
47 Overexpression of the Wilms' tumor gene WT1 in esophageal cancer. Anticancer Res 2004 0.84
48 Presence of B-cell clones in T-cell lymphoma. Eur J Haematol 2011 0.84
49 Effects of concomitant temozolomide and radiation therapies on WT1-specific T-cells in malignant glioma. Jpn J Clin Oncol 2010 0.84
50 WT1 peptide vaccine induces reduction in minimal residual disease in an Imatinib-treated CML patient. Eur J Haematol 2010 0.84
51 The effect on the proliferation and apoptosis of alloreactive T cells of cell dose in a murine MHC-mismatched hematopoietic cell transplantation model. Transpl Immunol 2003 0.83
52 WT1 peptide therapy for a patient with chemotherapy-resistant salivary gland cancer. Anticancer Res 2012 0.83
53 Phase I trial of Wilms' Tumor 1 (WT1) peptide vaccine with GM-CSF or CpG in patients with solid malignancy. Anticancer Res 2012 0.83
54 Low Wilms' tumor gene expression in tumor tissues predicts poor prognosis in patients with non-small-cell lung cancer. Cancer Invest 2011 0.83
55 WT1 peptide vaccination for the treatment of hematological malignancies: the present status and future direction. Rinsho Ketsueki 2009 0.82
56 The lck promoter-driven expression of the Wilms tumor gene WT1 blocks intrathymic differentiation of T-lineage cells. Int J Hematol 2003 0.82
57 Antilung cancer effect of WT1-specific cytotoxic T lymphocytes. Clin Cancer Res 2002 0.82
58 Diffuse large B-cell lymphoma in the young in Japan: a study by the Osaka Lymphoma Study Group. Am J Hematol 2007 0.82
59 HLA class II haplotype and quantitation of WT1 RNA in Japanese patients with paroxysmal nocturnal hemoglobinuria. Blood 2002 0.82
60 The Wilms' tumor gene WT1 is a common marker of progenitor cells in fetal liver. Biochem Biophys Res Commun 2005 0.81
61 Clinical and immunologic responses to very low-dose vaccination with WT1 peptide (5 microg/body) in a patient with chronic myelomonocytic leukemia. Int J Hematol 2007 0.81
62 Enhanced tumor immunity of WT1 peptide vaccination by interferon-β administration. Vaccine 2011 0.81
63 Successful treatment of life-threatening human herpesvirus-6 encephalitis with donor lymphocyte infusion in a patient who had undergone human leukocyte antigen-haploidentical nonmyeloablative stem cell transplantation. Transplantation 2004 0.81
64 Immunohistochemical detection of WT1 protein in endometrial cancer. Anticancer Res 2009 0.81
65 WT1 peptide vaccination combined with BCG-CWS is more efficient for tumor eradication than WT1 peptide vaccination alone. Cancer Immunol Immunother 2004 0.81
66 Change of CD20 Expression in Diffuse Large B-Cell Lymphoma Treated with Rituximab, an Anti-CD20 Monoclonal Antibody: A Study of the Osaka Lymphoma Study Group. Case Rep Oncol 2009 0.81
67 WT1 peptide immunotherapy for gynecologic malignancies resistant to conventional therapies: a phase II trial. J Cancer Res Clin Oncol 2012 0.81
68 WT1 (Wilms tumor 1) peptide immunotherapy for childhood rhabdomyosarcoma: a case report. Pediatr Hematol Oncol 2009 0.81
69 Wilms tumor 1 peptide vaccination combined with temozolomide against newly diagnosed glioblastoma: safety and impact on immunological response. Cancer Immunol Immunother 2015 0.80
70 WT1 peptide vaccination in combination with imatinib therapy for a patient with CML in the chronic phase. Int J Med Sci 2010 0.80
71 "Cancer antigen WT1 protein-derived peptide"-based treatment of cancer -toward the further development. Curr Med Chem 2008 0.80
72 WT1 peptide vaccine stabilized intractable ovarian cancer patient for one year: a case report. Anticancer Res 2011 0.80
73 WT1 enhances proliferation and impedes apoptosis in KRAS mutant NSCLC via targeting cMyc. Cell Physiol Biochem 2015 0.80
74 Frequency of intravascular large B-cell lymphoma in Japan: study of the Osaka Lymphoma Study Group. J Hematol Oncol 2011 0.80
75 WT1 peptide immunotherapy for cancer in children and young adults. Pediatr Blood Cancer 2010 0.80
76 Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka Lymphoma Study Group. Histopathology 2012 0.80
77 Identification of a WT1 protein-derived peptide, WT1, as a HLA-A 0206-restricted, WT1-specific CTL epitope. Microbiol Immunol 2008 0.80
78 A WT1 protein-derived, naturally processed 16-mer peptide, WT1(332), is a promiscuous helper peptide for induction of WT1-specific Th1-type CD4(+) T cells. Microbiol Immunol 2008 0.79
79 Prognostic significance of WT1 mRNA and anti-WT1 antibody levels in peripheral blood in patients with myelodysplastic syndromes. Leuk Res 2010 0.79
80 WT1 expression correlates with angiogenesis in endometrial cancer tissue. Anticancer Res 2010 0.79
81 Polymorphous lymphoproliferative disorder: a clinicopathological analysis. Virchows Arch 2010 0.78
82 Vaccination with WT-1 (Wilms' tumor gene-1) peptide and BCG-CWS in melanoma. Eur J Dermatol 2012 0.78
83 Prognostic value of WT1 protein expression level and MIB-1 staining index as predictor of response to WT1 immunotherapy in glioblastoma patients. Brain Tumor Pathol 2010 0.78
84 WT1 peptide vaccine, one of the most promising cancer vaccines: its present status and the future prospects. Immunotherapy 2010 0.78
85 Sensitive immunohistochemical detection of WT1 protein in tumors with anti-WT1 antibody against WT1 235 peptide. Cancer Sci 2010 0.78
86 WT1 peptide vaccine as a paradigm for "cancer antigen-derived peptide"-based immunotherapy for malignancies: successful induction of anti-cancer effect by vaccination with a single kind of WT1 peptide. Anticancer Agents Med Chem 2009 0.77
87 Clinical evaluation of WT1 mRNA expression levels in peripheral blood and bone marrow in patients with myelodysplastic syndromes. Leuk Lymphoma 2012 0.77
88 Wilm's tumor gene WT1 peptide immunotherapy for pulmonary metastasis from adenoid cystic carcinoma of the salivary gland. Oral Oncol 2010 0.77
89 A clear correlation between WT1-specific Th response and clinical response in WT1 CTL epitope vaccination. Anticancer Res 2010 0.77
90 Diffuse large B-cell lymphoma with a high number of epithelioid histiocytes (lymphoepithelioid B-cell lymphoma): a study of Osaka Lymphoma Study Group. Virchows Arch 2009 0.77
91 Prognostic significance of specific anti-WT1 IgG antibody level in plasma in patients with ovarian carcinoma. Cancer Med 2014 0.77
92 The expression of anamorsin in diffuse large B cell lymphoma: possible prognostic biomarker for low IPI patients. Leuk Lymphoma 2008 0.77
93 Monitoring minimal residual disease in leukemia using real-time quantitative polymerase chain reaction for Wilms tumor gene (WT1). Int J Hematol 2003 0.77
94 HLA-DPB1*05: 01-restricted WT1332-specific TCR-transduced CD4+ T lymphocytes display a helper activity for WT1-specific CTL induction and a cytotoxicity against leukemia cells. J Immunother 2013 0.77
95 Treatment of severe life-threatening graft-versus-host disease by autologous peripheral blood stem cell transplantation using a nonmyeloablative preconditioning regimen. Haematologica 2003 0.77
96 [Immunotherapy targeting the Wilms' tumor 1 gene product for patients with malignant brain tumors]. Brain Nerve 2009 0.76
97 Wilms' tumor 1 is involved in tumorigenicity of glioblastoma by regulating cell proliferation and apoptosis. Anticancer Res 2014 0.76
98 Recognition of a natural WT1 epitope by a modified WT1 peptide-specific T-cell receptor. Anticancer Res 2012 0.76
99 [Clinical course of the disease and the level of WT1 mRNA in 191 patients with acute myeloid leukemia (AML): joint research by 23 institutions in Japan]. Rinsho Ketsueki 2005 0.76
100 Two distinct effector memory cell populations of WT1 (Wilms' tumor gene 1)-specific cytotoxic T lymphocytes in acute myeloid leukemia patients. Cancer Immunol Immunother 2015 0.76
101 Biased usage of T cell receptor β-chain variable region genes of Wilms' tumor gene (WT1)-specific CD8+ T cells in patients with solid tumors and healthy donors. Cancer Sci 2012 0.76
102 Absence of mutations in the Wilms' tumor gene WT1 in primary breast cancer. Jpn J Clin Oncol 2004 0.76
103 Combination of tacrolimus, methotrexate, and methylprednisolone prevents acute but not chronic graft-versus-host disease in unrelated bone marrow transplantation. Transplantation 2002 0.76
104 Vaccination strategies to improve outcome of hematopoietic stem cell transplant in leukemia patients: early evidence and future prospects. Expert Rev Hematol 2014 0.76
105 Differential radiation sensitivity to morphological, functional and molecular changes of human thyroid tissues and bone marrow cells maintained in SCID mice. Mutat Res 2008 0.75
106 [Cancer immunotherapy targeting WT1 product which overexpressess in various kinds of malignant neoplasms]. Tanpakushitsu Kakusan Koso 2003 0.75
107 [III. Peptide vaccination therapy against brain tumors]. Gan To Kagaku Ryoho 2015 0.75
108 Wilms' Tumor Gene 1 (WT1) Peptide Vaccine Therapy for Hematological Malignancies: From CTL Epitope Identification to Recent Progress in Clinical Studies Including a Cure-Oriented Strategy. Oncol Res Treat 2017 0.75
109 Frequency of myeloid dendritic cells can predict the efficacy of Wilms' tumor 1 peptide vaccination. Anticancer Res 2011 0.75
110 [Cellular and humoral immune responses against WT1 products overexpressed in hematopoietic malignancies]. Rinsho Ketsueki 2002 0.75
111 An Essential Role of the Avidity of T-Cell Receptor in Differentiation of Self-Antigen-reactive CD8+ T Cells. J Immunother 2016 0.75
112 Functional human Th17 clones with WT1-specific helper activity. Cancer Immunol Immunother 2012 0.75
113 WT1(235), a ninemer peptide derived from Wilms' tumor gene product, is a candidate peptide for the vaccination of HLA-A*0201-positive patients with hematopoietic malignancies. Int J Hematol 2005 0.75
114 [Identification of myeloma-initiating cells and development of their targeting therapy]. Rinsho Ketsueki 2013 0.75
115 Tumor immunology. Editorial overview. Curr Opin Immunol 2008 0.75
116 [WT1 peptide-based immunotherapy for the treatment of malignancies: focusing on hematological neoplasms]. Rinsho Ketsueki 2011 0.75
117 Intravenous administration of MIP-1alpha with intra-tumor injection of P. acnes shows potent anti-tumor effect. Int Immunopharmacol 2007 0.75