PubRank

Hannu Kankaanranta

Author PubWeight™ 38.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nitric oxide production and signaling in inflammation. Curr Drug Targets Inflamm Allergy 2005 2.37
2 c-Jun NH2-terminal kinase inhibitor anthra(1,9-cd)pyrazol-6(2H)-one reduces inducible nitric-oxide synthase expression by destabilizing mRNA in activated macrophages. Mol Pharmacol 2003 1.12
3 Beta2-agonists potentiate corticosteroid-induced neutrophil survival. COPD 2008 1.10
4 Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages. Mol Pharmacol 2002 1.05
5 Down-regulation of tristetraprolin expression results in enhanced IL-12 and MIP-2 production and reduced MIP-3alpha synthesis in activated macrophages. Mediators Inflamm 2006 1.03
6 Eosinophil apoptosis as a therapeutic target in allergic asthma. Basic Clin Pharmacol Toxicol 2013 1.02
7 Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis. Blood 2002 1.02
8 Inhibition of classical PKC isoenzymes downregulates STAT1 activation and iNOS expression in LPS-treated murine J774 macrophages. Br J Pharmacol 2006 0.98
9 Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: implication in inducible nitric oxide synthase expression. BMC Pharmacol 2006 0.96
10 Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes. Mediators Inflamm 2005 0.95
11 Divergent effect of mometasone on human eosinophil and neutrophil apoptosis. Life Sci 2002 0.93
12 P38 mitogen-activated protein kinase inhibitor SB203580 has a bi-directional effect on iNOS expression and NO production. Eur J Pharmacol 2002 0.91
13 Inhibition of tristetraprolin expression by dexamethasone in activated macrophages. Biochem Pharmacol 2005 0.90
14 JNK inhibitor SP600125 reduces COX-2 expression by attenuating mRNA in activated murine J774 macrophages. Int Immunopharmacol 2006 0.88
15 JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages. Mediators Inflamm 2006 0.87
16 Alveolar and bronchial nitric oxide output in healthy children. Pediatr Pulmonol 2008 0.85
17 Nitric oxide induces apoptosis in GM-CSF-treated eosinophils via caspase-6-dependent lamin and DNA fragmentation. Pulm Pharmacol Ther 2010 0.85
18 Peripheral inflammation in patients with asthmatic symptoms but normal lung function. J Asthma 2005 0.84
19 Adipokine resistin predicts anti-inflammatory effect of glucocorticoids in asthma. J Inflamm (Lond) 2011 0.84
20 Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5. J Allergy Clin Immunol 2003 0.84
21 Bacterial DNA delays human eosinophil apoptosis. Pulm Pharmacol Ther 2008 0.84
22 Increased alveolar nitric oxide concentration and high levels of leukotriene B(4) and 8-isoprostane in exhaled breath condensate in patients with asbestosis. Thorax 2007 0.84
23 Local and systemic oxidant/antioxidant status before and during lung cancer radiotherapy. Free Radic Res 2009 0.82
24 Aurothiomalate inhibits COX-2 expression in chondrocytes and in human cartilage possibly through its effects on COX-2 mRNA stability. Eur J Pharmacol 2008 0.82
25 Nitric oxide-induced eosinophil apoptosis is dependent on mitochondrial permeability transition (mPT), JNK and oxidative stress: apoptosis is preceded but not mediated by early mPT-dependent JNK activation. Respir Res 2012 0.82
26 Pulmonary inflammation in asbestos-exposed subjects with borderline parenchymal changes on HRCT. Respir Med 2010 0.81
27 Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1. Br J Pharmacol 2013 0.81
28 The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils. J Inflamm (Lond) 2006 0.80
29 Cost-effectiveness analysis of budesonide/formoterol maintenance and reliever therapy versus fixed combination treatments for asthma in Finland*. Curr Med Res Opin 2008 0.80
30 Phosphodiesterase 4 inhibitors delay human eosinophil and neutrophil apoptosis in the absence and presence of salbutamol. Pulm Pharmacol Ther 2007 0.80
31 [Update on current care guidelines: asthma]. Duodecim 2013 0.80
32 Levocetirizine and cytokine production and apoptosis of human eosinophils. Allergy Asthma Proc 2007 0.80
33 Histamine reverses IL-5-afforded human eosinophil survival by inducing apoptosis: pharmacological evidence for a novel mechanism of action of histamine. Pulm Pharmacol Ther 2007 0.79
34 Inhibition of iNOS expression and NO production by anti-inflammatory steroids. Reversal by histone deacetylase inhibitors. Pulm Pharmacol Ther 2007 0.79
35 Cost effectiveness of adding budesonide/formoterol to tiotropium in COPD in four Nordic countries. Respir Med 2013 0.78
36 Orazipone inhibits activation of inflammatory transcription factors nuclear factor-kappa B and signal transducer and activator of transcription 1 and decreases inducible nitric-oxide synthase expression and nitric oxide production in response to inflammatory stimuli. J Pharmacol Exp Ther 2007 0.78
37 Bronchial diffusing capacity of nitric oxide is increased in patients with allergic rhinitis. Int Arch Allergy Immunol 2008 0.78
38 c-Jun N-terminal kinase mediates constitutive human eosinophil apoptosis. Pulm Pharmacol Ther 2006 0.77
39 Janus kinase 3 inhibitor WHI-P154 in macrophages activated by bacterial endotoxin: differential effects on the expression of iNOS, COX-2 and TNF-alpha. Int Immunopharmacol 2007 0.77
40 [Pulmonary nocardiosis in a farmer]. Duodecim 2011 0.76
41 Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo. Basic Clin Pharmacol Toxicol 2009 0.76
42 [Update on current care guideline: chronic obstructive pulmonary disease (COPD)]. Duodecim 2014 0.76
43 First-generation antihistamines diphenhydramine and chlorpheniramine reverse cytokine-afforded eosinophil survival by enhancing apoptosis. Allergy Asthma Proc 2007 0.75
44 Concurrent decline of several antioxidants and markers of oxidative stress during combination chemotherapy for small cell lung cancer. Clin Biochem 2009 0.75
45 Eosinophil intracellular signalling: apoptosis. Methods Mol Biol 2014 0.75
46 [Update on current care guidelines. Safe use of non-steroidal anti-inflammatory drugs]. Duodecim 2009 0.75
47 Ketotifen induces primary necrosis of human eosinophils. J Ocul Pharmacol Ther 2005 0.75
48 Salbutamol increases tristetraprolin expression in macrophages. Life Sci 2007 0.75