Published in Apoptosis on June 01, 2008
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The evolving role of radiation therapy in the management of malignant melanoma. Int J Radiat Oncol Biol Phys (2011) 1.04
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Multifaceted approach to resveratrol bioactivity: Focus on antioxidant action, cell signaling and safety. Oxid Med Cell Longev (2010) 0.97
Resveratrol: Biological and pharmaceutical properties as anticancer molecule. Biofactors (2010) 0.93
Therapeutic implications of targeting the PI3Kinase/AKT/mTOR signaling module in melanoma therapy. Am J Cancer Res (2012) 0.90
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Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18. J Transl Med (2011) 0.84
Inhibition of COX-2 expression by topical diclofenac enhanced radiation sensitivity via enhancement of TRAIL in human prostate adenocarcinoma xenograft model. BMC Urol (2013) 0.83
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The radiosensitization effects of Endostar on human lung squamous cancer cells H-520. Cancer Cell Int (2010) 0.81
The effect of a novel frizzled 8-related antiproliferative factor on in vitro carcinoma and melanoma cell proliferation and invasion. Invest New Drugs (2011) 0.81
The effects of resveratrol and selected metabolites on the radiation and antioxidant response. Cancer Biol Ther (2011) 0.80
The paradox role of caspase cascade in ionizing radiation therapy. J Biomed Sci (2016) 0.77
TRAIL and guardian angel of genome integrity: ATM boards TRAIL blazer. J Cancer Res Clin Oncol (2011) 0.77
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Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat Rev Cancer (2002) 4.76
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Mitochondria in cancer cells: what is so special about them? Trends Cell Biol (2008) 2.97
Cyclooxygenase 2: a molecular target for cancer prevention and treatment. Trends Pharmacol Sci (2003) 2.91
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Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity. Mol Cell Biol (2004) 1.90
Killing cancer cells by flipping the Bcl-2/Bax switch. Cancer Cell (2005) 1.79
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Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein. Mol Cancer Ther (2006) 1.69
Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol. Cancer Res (2004) 1.67
Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5. Cell Death Differ (2008) 1.61
Cytokine-based therapy and biochemotherapy for advanced melanoma. Clin Cancer Res (2006) 1.53
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Aberrant regulation and function of wild-type p53 in radioresistant melanoma cells. Cell Growth Differ (2000) 1.25
Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression. J Immunol (2001) 1.23
p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells. Oncogene (2001) 1.16
Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression. Exp Cell Res (2007) 1.14
Recent advances in melanoma biology. Oncologist (2004) 1.10
Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor alpha-mediated pathway. J Biol Chem (2004) 1.06
Resveratrol inhibits firefly luciferase. Biochem Biophys Res Commun (2006) 0.97
Comprehensive analysis of the p53 status in mucosal and cutaneous melanomas. Int J Cancer (2006) 0.95
Sequential treatment by ionizing radiation and sodium arsenite dramatically accelerates TRAIL-mediated apoptosis of human melanoma cells. Cancer Res (2007) 0.91
The effect of sunscreen on melanoma risk. Dermatol Clin (2002) 0.85
Current concepts for the combined treatment modality of ionizing radiation with anticancer agents. Curr Pharm Des (2007) 0.84
No life without death. Adv Cancer Res (2007) 0.84
Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases. Free Radic Biol Med (2003) 2.13
Mechanism of radiation-induced bystander effects: a unifying model. J Pharm Pharmacol (2008) 2.07
Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathway. Proc Natl Acad Sci U S A (2005) 1.92
Mitochondrial function and nuclear factor-kappaB-mediated signaling in radiation-induced bystander effects. Cancer Res (2008) 1.61
ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis. Oncogene (2003) 1.57
The time and spatial effects of bystander response in mammalian cells induced by low dose radiation. Carcinogenesis (2005) 1.41
Radiation induced non-targeted response: mechanism and potential clinical implications. Curr Mol Pharmacol (2011) 1.36
TGFBI deficiency predisposes mice to spontaneous tumor development. Cancer Res (2009) 1.34
Immortalization of human small airway epithelial cells by ectopic expression of telomerase. Carcinogenesis (2005) 1.31
Critical role of oxidative stress in estrogen-induced carcinogenesis. Proc Natl Acad Sci U S A (2003) 1.26
Radiation-induced bystander signaling pathways in human fibroblasts: a role for interleukin-33 in the signal transmission. Cell Signal (2010) 1.24
Arsenic induced mitochondrial DNA damage and altered mitochondrial oxidative function: implications for genotoxic mechanisms in mammalian cells. Cancer Res (2007) 1.17
Genomic instability and bystander effects induced by high-LET radiation. Oncogene (2003) 1.17
Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression. Exp Cell Res (2007) 1.14
Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: a role of suppression of the PI3K-AKT pathway. Oncogene (2005) 1.13
Mechanisms of the genotoxicity of crocidolite asbestos in mammalian cells: implication from mutation patterns induced by reactive oxygen species. Environ Health Perspect (2002) 1.13
Estrogen-induced breast cancer: alterations in breast morphology and oxidative stress as a function of estrogen exposure. Toxicol Appl Pharmacol (2008) 1.12
Loss of Betaig-h3 protein is frequent in primary lung carcinoma and related to tumorigenic phenotype in lung cancer cells. Mol Carcinog (2006) 1.12
Assessment of low linear energy transfer radiation-induced bystander mutagenesis in a three-dimensional culture model. Cancer Res (2005) 1.11
Mitochondrial damage mediates genotoxicity of arsenic in mammalian cells. Cancer Res (2005) 1.10
Targeting of cell survival genes using small interfering RNAs (siRNAs) enhances radiosensitivity of Grade II chondrosarcoma cells. J Orthop Res (2007) 1.09
Arsenic induces oxidative DNA damage in mammalian cells. Mol Cell Biochem (2002) 1.08
Downregulation of Betaig-h3 gene is causally linked to tumorigenic phenotype in asbestos treated immortalized human bronchial epithelial cells. Oncogene (2002) 1.08
Epigenetic inactivation of Betaig-h3 gene in human cancer cells. Cancer Res (2006) 1.07
Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor alpha-mediated pathway. J Biol Chem (2004) 1.06
Opposite roles of FAP-1 and dynamin in the regulation of Fas (CD95) translocation to the cell surface and susceptibility to Fas ligand-mediated apoptosis. J Biol Chem (2005) 1.02
Phytoestrogens and breast cancer prevention: possible mechanisms of action. Environ Health Perspect (2008) 1.02
Methylation screening of the TGFBI promoter in human lung and prostate cancer by methylation-specific PCR. BMC Cancer (2008) 0.99
TGFBI expression reduces in vitro and in vivo metastatic potential of lung and breast tumor cells. Cancer Lett (2011) 0.98
Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases. J Toxicol Environ Health B Crit Rev (2011) 0.98
BigH3 protein expression as a marker for breast cancer. Int J Mol Med (2008) 0.98
Mutagenicity of cadmium in mammalian cells: implication of oxidative DNA damage. Mutat Res (2004) 0.97
Interaction between radiation-induced adaptive response and bystander mutagenesis in mammalian cells. Radiat Res (2003) 0.97
Tetramethylpyrazine (TMP) protects against sodium arsenite-induced nephrotoxicity by suppressing ROS production, mitochondrial dysfunction, pro-inflammatory signaling pathways and programed cell death. Arch Toxicol (2014) 0.96
A role for TRAIL/TRAIL-R2 in radiation-induced apoptosis and radiation-induced bystander response of human neural stem cells. Apoptosis (2014) 0.95
Neoplastic transformation of human small airway epithelial cells induced by arsenic. Mol Med (2008) 0.95
Disruption of IGF-1R signaling increases TRAIL-induced apoptosis: a new potential therapy for the treatment of melanoma. Exp Cell Res (2010) 0.95
Regulation of early signaling and gene expression in the alpha-particle and bystander response of IMR-90 human fibroblasts. BMC Med Genomics (2010) 0.95
Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression. Exp Cell Res (2006) 0.94
Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells. Cancer Res (2009) 0.94
Malignant transformation of human benign prostate epithelial cells by high linear energy transfer alpha-particles. Int J Oncol (2007) 0.93
Effect of medium on chromatin damage in bystander mammalian cells. Radiat Res (2004) 0.92
Cytoplasmic irradiation results in mitochondrial dysfunction and DRP1-dependent mitochondrial fission. Cancer Res (2013) 0.92
A novel mechanism for p53 to regulate its target gene ECK in signaling apoptosis. Mol Cancer Res (2006) 0.91
Sequential treatment by ionizing radiation and sodium arsenite dramatically accelerates TRAIL-mediated apoptosis of human melanoma cells. Cancer Res (2007) 0.91
Malignant transformation of human bronchial epithelial cells with the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Int J Cancer (2003) 0.91
The role of TGFBI in mesothelioma and breast cancer: association with tumor suppression. BMC Cancer (2012) 0.90
The HINT1 tumor suppressor regulates both gamma-H2AX and ATM in response to DNA damage. J Cell Biol (2008) 0.90
Down-regulation of Betaig-h3 gene is involved in the tumorigenesis in human bronchial epithelial cells induced by heavy-ion radiation. Radiat Res (2004) 0.89
Transforming growth factor-β-induced protein (TGFBI) suppresses mesothelioma progression through the Akt/mTOR pathway. Int J Oncol (2011) 0.89
Differential impact of mouse Rad9 deletion on ionizing radiation-induced bystander effects. Radiat Res (2005) 0.88
Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells. Exp Cell Res (2006) 0.87
High-throughput antibody-based assays to identify and quantify radiation-responsive protein biomarkers. Int J Radiat Biol (2010) 0.87
Demonstration of a radiation-induced bystander effect for low dose low LET beta-particles. Radiat Environ Biophys (2007) 0.87
Effects of irradiated medium with or without cells on bystander cell responses. Mutat Res (2002) 0.87
Induction of apoptotic death and retardation of neuronal differentiation of human neural stem cells by sodium arsenite treatment. Exp Cell Res (2012) 0.85
Consequences of cytoplasmic irradiation: studies from microbeam. J Radiat Res (2009) 0.85
Radiation response and regulation of apoptosis induced by a combination of TRAIL and CHX in cells lacking mitochondrial DNA: a role for NF-κB-STAT3-directed gene expression. Exp Cell Res (2011) 0.85
Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells. Part Fibre Toxicol (2009) 0.84
Mutagenicity of diesel exhaust particles mediated by cell-particle interaction in mammalian cells. Toxicology (2006) 0.84
Genotoxic mechanisms of asbestos fibers: role of extranuclear targets. Chem Res Toxicol (2007) 0.84
p16INK4a downregulation is involved in immortalization of primary human prostate epithelial cells induced by telomerase. Mol Carcinog (2008) 0.84
Regulation of apoptosis in human melanoma and neuroblastoma cells by statins, sodium arsenite and TRAIL: a role of combined treatment versus monotherapy. Apoptosis (2011) 0.84
Mitochondria-derived reactive intermediate species mediate asbestos-induced genotoxicity and oxidative stress-responsive signaling pathways. Environ Health Perspect (2012) 0.84
Radiation Induced Bystander Effect in vivo. Acta Med Nagasaki (2008) 0.84
Induction of germline cell cycle arrest and apoptosis by sodium arsenite in Caenorhabditis elegans. Chem Res Toxicol (2007) 0.83
Quantification of CD59- mutants in human-hamster hybrid (AL) cells by flow cytometry. Mutat Res (2005) 0.83
RecQL4 helicase amplification is involved in human breast tumorigenesis. PLoS One (2013) 0.83
Suppression of the proinflammatory response of metastatic melanoma cells increases TRAIL-induced apoptosis. J Cell Biochem (2011) 0.83
The NRF2 activation and antioxidative response are not impaired overall during hyperoxia-induced lung epithelial cell death. Oxid Med Cell Longev (2013) 0.83
New insight into intrachromosomal deletions induced by chrysotile in the gpt delta transgenic mutation assay. Environ Health Perspect (2007) 0.82
Gap junction communication and the propagation of bystander effects induced by microbeam irradiation in human fibroblast cultures: the impact of radiation quality. Radiat Res (2013) 0.82
Radon-induced alterations in micro-RNA expression profiles in transformed BEAS2B cells. J Toxicol Environ Health A (2013) 0.82
MiR-663 inhibits radiation-induced bystander effects by targeting TGFB1 in a feedback mode. RNA Biol (2014) 0.82
Radiation-induced glioblastoma signaling cascade regulates viability, apoptosis and differentiation of neural stem cells (NSC). Apoptosis (2014) 0.82
Detection of chromosomal instability in bystander cells after Si490-ion irradiation. Radiat Res (2011) 0.81
Survival of mammalian cells under high vacuum condition for ion bombardment. Cryobiology (2004) 0.80
Participation of gap junction communication in potentially lethal damage repair and DNA damage in human fibroblasts exposed to low- or high-LET radiation. Mutat Res (2013) 0.80
Allelic imbalance at 11p15.5-15.4 correlated with c-Ha-ras mutation during radiation-induced neoplastic transformation of human breast epithelial cells. Int J Cancer (2003) 0.80
Radiation-induced bystander signaling from somatic cells to germ cells in Caenorhabditis elegans. Radiat Res (2013) 0.80
Intrachromosomal changes and genomic instability in site-specific microbeam-irradiated and bystander human-hamster hybrid cells. Radiat Res (2011) 0.78
Mitochondrial alteration in malignantly transformed human small airway epithelial cells induced by α-particles. Int J Cancer (2012) 0.78
Radon-induced reduced apoptosis in human bronchial epithelial cells with knockdown of mitochondria DNA. J Toxicol Environ Health A (2012) 0.77
Immunochemical analysis of protein expression in breast epithelial cells transformed by estrogens and high linear energy transfer (LET) radiation. Histochem Cell Biol (2005) 0.77
RAD9 deficiency enhances radiation induced bystander DNA damage and transcriptomal response. Radiat Oncol (2014) 0.77
Sodium arsenite exposure inhibits AKT and Stat3 activation, suppresses self-renewal and induces apoptotic death of embryonic stem cells. Apoptosis (2013) 0.77
Effects of irradiated medium on chromatid aberrations in mammalian cells using double mylar dishes. Biol Sci Space (2004) 0.77
Increased susceptibility of human small airway epithelial cells to apoptosis after long term arsenate treatment. Sci Total Environ (2008) 0.76
Beta catenin is associated with breast cancer progression in vitro. Int J Oncol (2005) 0.76
The complete nucleotide sequence of Chinese hamster (Cricetulus griseus) mitochondrial DNA. DNA Seq (2007) 0.76
Environmental mutagens induced transversions but not transitions in regulatory region of mitochondrial DNA. J Toxicol Environ Health A (2009) 0.76
Regulation of viability, differentiation and death of human melanoma cells carrying neural stem cell biomarkers: a possibility for neural trans-differentiation. Apoptosis (2015) 0.76
Oxidative damage in various tissues of rats exposed to radon. J Toxicol Environ Health A (2012) 0.76
Induction of a bystander chromosomal damage of He-ion microbeams in mammalian cells. Biol Sci Space (2003) 0.75
No significant level of inheritable interchromosomal aberrations in the progeny of bystander primary human fibroblast after alpha particle irradiation. Adv Space Res (2013) 0.75