Published in Free Radic Biol Med on April 20, 2008
Generation and biological activities of oxidized phospholipids. Antioxid Redox Signal (2010) 2.04
The role of oxidized phospholipids in atherosclerosis. J Lipid Res (2008) 1.51
Isoprostane generation and function. Chem Rev (2011) 1.41
The innate immune response to products of phospholipid peroxidation. Biochim Biophys Acta (2012) 1.20
A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipids. Free Radic Biol Med (2009) 1.19
High-density lipoprotein and 4F peptide reduce systemic inflammation by modulating intestinal oxidized lipid metabolism: novel hypotheses and review of literature. Arterioscler Thromb Vasc Biol (2012) 1.11
Arsenic exacerbates atherosclerotic lesion formation and inflammation in ApoE-/- mice. Toxicol Appl Pharmacol (2009) 1.08
Short-term stimulation of calcium-permeable transient receptor potential canonical 5-containing channels by oxidized phospholipids. Arterioscler Thromb Vasc Biol (2010) 0.96
Differential regulation of endothelial cell permeability by high and low doses of oxidized 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphocholine. Am J Respir Cell Mol Biol (2011) 0.95
Structural identification and cardiovascular activities of oxidized phospholipids. Circ Res (2012) 0.90
Lipidomic analysis of human plasma reveals ether-linked lipids that are elevated in morbidly obese humans compared to lean. Diabetol Metab Syndr (2013) 0.90
Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier function. Microvasc Res (2011) 0.88
Oxidized phospholipids: biomarker for cardiovascular diseases. Int J Biochem Cell Biol (2008) 0.86
A role for VEGFR2 activation in endothelial responses caused by barrier disruptive OxPAPC concentrations. PLoS One (2012) 0.84
Anti-inflammatory peptides grab on to the whiskers of atherogenic oxidized lipids. Biochim Biophys Acta (2009) 0.83
Reductive metabolism increases the proinflammatory activity of aldehyde phospholipids. J Lipid Res (2011) 0.81
Aldose reductase decreases endoplasmic reticulum stress in ischemic hearts. Chem Biol Interact (2008) 0.80
Trp53 deficient mice predisposed to preterm birth display region-specific lipid alterations at the embryo implantation site. Sci Rep (2016) 0.77
Protein phosphatase 2A promotes endothelial survival via stabilization of translational inhibitor 4E-BP1 following exposure to tumor necrosis factor-α. Arterioscler Thromb Vasc Biol (2011) 0.77
Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo. J Biol Chem (1997) 3.91
Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids. Proc Natl Acad Sci U S A (2006) 3.03
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells. Arterioscler Thromb Vasc Biol (2006) 2.90
The combined role of P- and E-selectins in atherosclerosis. J Clin Invest (1998) 2.53
Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages. Arterioscler Thromb Vasc Biol (2005) 2.41
Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase. Circ Res (2003) 2.33
Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2. Arterioscler Thromb Vasc Biol (2003) 2.15
Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species. Am J Physiol Heart Circ Physiol (2005) 2.12
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage. Nature (2002) 2.06
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC. Circ Res (2006) 1.89
Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac. Circ Res (2004) 1.88
Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells. Circ Res (2000) 1.80
Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study. Arterioscler Thromb Vasc Biol (2007) 1.79
Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids. Circ Res (2006) 1.78
Role of vascular cell adhesion molecule-1 and fibronectin connecting segment-1 in monocyte rolling and adhesion on early atherosclerotic lesions. Circ Res (2000) 1.71
Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions. Arterioscler Thromb Vasc Biol (2002) 1.62
Oxidized phospholipid-induced endothelial cell/monocyte interaction is mediated by a cAMP-dependent R-Ras/PI3-kinase pathway. Arterioscler Thromb Vasc Biol (2003) 1.53
Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils. Proc Natl Acad Sci U S A (1999) 1.53
Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT. Blood (2002) 1.50
Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein. J Biol Chem (2003) 1.49
Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells. Genome Biol (2007) 1.46
Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-8 synthesis. Formation of these oxidized phospholipids in response to interleukin-1beta. J Biol Chem (2001) 1.44
Receptors involved in the oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidylinositol-anchored protein. J Biol Chem (2003) 1.42
Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo. J Biol Chem (2007) 1.37
Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products. Circ Res (2004) 1.37
Minimally oxidized low-density lipoprotein induces tissue factor expression in cultured human endothelial cells. Am J Pathol (1991) 1.36
Oxidized phospholipids trigger atherogenic inflammation in murine arteries. Arterioscler Thromb Vasc Biol (2004) 1.29
Increased transcription of IL-8 in endothelial cells is differentially regulated by TNF-alpha and oxidized phospholipids. Arterioscler Thromb Vasc Biol (2001) 1.26
Evidence for a role of phospholipid oxidation products in atherogenesis. Trends Cardiovasc Med (2001) 1.26
Blocking very late antigen-4 integrin decreases leukocyte entry and fatty streak formation in mice fed an atherogenic diet. Circ Res (1999) 1.18
Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids. Arterioscler Thromb Vasc Biol (2006) 1.17
Minimally modified low-density lipoprotein induces monocyte adhesion to endothelial connecting segment-1 by activating beta1 integrin. J Clin Invest (1999) 1.14
Lipoxygenase products increase monocyte adhesion to human aortic endothelial cells. Arterioscler Thromb Vasc Biol (1999) 1.13
Tiam1 and betaPIX mediate Rac-dependent endothelial barrier protective response to oxidized phospholipids. J Cell Physiol (2007) 1.12
Protein targets of oxidized phospholipids in endothelial cells. J Lipid Res (2007) 1.11
OKL38 is an oxidative stress response gene stimulated by oxidized phospholipids. J Lipid Res (2006) 1.09
A role for neutral sphingomyelinase activation in the inhibition of LPS action by phospholipid oxidation products. J Lipid Res (2006) 1.08
Signaling pathways involved in OxPAPC-induced pulmonary endothelial barrier protection. Microvasc Res (2007) 1.08
Inflammatory profile of oxidized phospholipids. Thromb Haemost (2007) 1.08
Oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: implication of NADPH oxidase. Free Radic Biol Med (2005) 1.05
Hydroxy alkenal phospholipids regulate inflammatory functions of endothelial cells. Vascul Pharmacol (2002) 1.05
Oxidized LDL contains inflammatory PAF-like phospholipids. Trends Cardiovasc Med (2001) 0.99
Effects of native and modified low-density lipoproteins on monocyte recruitment in atherosclerosis. Hypertension (2007) 0.98
Oxidized phospholipids in oxidized low-density lipoprotein reduce the activity of tissue factor pathway inhibitor through association with its carboxy-terminal region. Antioxid Redox Signal (2004) 0.94
Isolevuglandins, oxidatively truncated phospholipids, and atherosclerosis. Ann N Y Acad Sci (2005) 0.89
In vitro study of the cytotoxicity of isolated oxidized lipid low-density lipoproteins fractions in human endothelial cells: relationship with the glutathione status and cell morphology. Free Radic Biol Med (2000) 0.87
Induction of P-selectin by oxidized lipoproteins. Separate effects on synthesis and surface expression. Circ Res (1997) 0.86
Oxidized low-density lipoprotein downregulates endothelial basic fibroblast growth factor through a pertussis toxin-sensitive G-protein pathway: mediator role of platelet-activating factor-like phospholipids. Circulation (2001) 0.86
Induction of monocyte binding to endothelial cells by MM-LDL: role of lipoxygenase metabolites. Arterioscler Thromb Vasc Biol (1999) 0.83
Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids. Proc Natl Acad Sci U S A (2006) 3.03
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells. Arterioscler Thromb Vasc Biol (2006) 2.90
Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway. J Biol Chem (2004) 1.52
A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipids. Free Radic Biol Med (2009) 1.19
Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids. Arterioscler Thromb Vasc Biol (2006) 1.17
Finasteride associated melasma in a Caucasian male. J Drugs Dermatol (2014) 0.86
Acquired perforating dermatosis associated with metastatic colon cancer. Dermatol Online J (2011) 0.81
A clinical and biological evaluation of a novel, noninvasive radiofrequency device for the long-term reduction of adipose tissue. Lasers Surg Med (2014) 0.79
An unusual presentation and distribution of generalized eruptive syringomas. Skinmed (2013) 0.75
Waxy indurated plaques on the eyelids. Cutis (2015) 0.75