Published in PLoS Pathog on February 29, 2008
Bacterial growth and cell division: a mycobacterial perspective. Microbiol Mol Biol Rev (2008) 2.01
Comparative analysis of two complete Corynebacterium ulcerans genomes and detection of candidate virulence factors. BMC Genomics (2011) 1.75
Complete genome sequence, lifestyle, and multi-drug resistance of the human pathogen Corynebacterium resistens DSM 45100 isolated from blood samples of a leukemia patient. BMC Genomics (2012) 1.35
Exit from dormancy in microbial organisms. Nat Rev Microbiol (2010) 1.35
More than just lysins: peptidoglycan hydrolases tailor the cell wall. Curr Opin Microbiol (2011) 1.31
Characterization of a Clp protease gene regulator and the reaeration response in Mycobacterium tuberculosis. PLoS One (2010) 1.28
A Mycobacterium tuberculosis Rpf double-knockout strain exhibits profound defects in reactivation from chronic tuberculosis and innate immunity phenotypes. Infect Immun (2008) 1.24
Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria. PLoS Pathog (2010) 1.21
Mycobacterium tuberculosis ClpX interacts with FtsZ and interferes with FtsZ assembly. PLoS One (2010) 1.19
Simultaneous analysis of multiple Mycobacterium tuberculosis knockdown mutants in vitro and in vivo. PLoS One (2010) 1.14
To catch a killer. What can mycobacterial models teach us about Mycobacterium tuberculosis pathogenesis? Curr Opin Microbiol (2009) 1.11
Extracytoplasmic function sigma factors regulate expression of the Bacillus subtilis yabE gene via a cis-acting antisense RNA. J Bacteriol (2008) 1.11
Developmental biology of Streptomyces from the perspective of 100 actinobacterial genome sequences. FEMS Microbiol Rev (2013) 1.07
Latent tuberculosis infection: myths, models, and molecular mechanisms. Microbiol Mol Biol Rev (2014) 1.06
Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase. Nucleic Acids Res (2010) 1.03
Siderocalin inhibits the intracellular replication of Mycobacterium tuberculosis in macrophages. FEMS Immunol Med Microbiol (2009) 1.02
Beyond growth: novel functions for bacterial cell wall hydrolases. Trends Microbiol (2012) 0.99
Rv2190c, an NlpC/P60 family protein, is required for full virulence of Mycobacterium tuberculosis. PLoS One (2012) 0.96
Cell division in Corynebacterineae. Front Microbiol (2014) 0.91
Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria. PLoS Pathog (2013) 0.89
Mycobacterium tuberculosis CwsA interacts with CrgA and Wag31, and the CrgA-CwsA complex is involved in peptidoglycan synthesis and cell shape determination. J Bacteriol (2012) 0.89
Septal localization of the Mycobacterium tuberculosis MtrB sensor kinase promotes MtrA regulon expression. J Biol Chem (2012) 0.88
Use of a mariner-based transposon mutagenesis system to isolate Clostridium perfringens mutants deficient in gliding motility. J Bacteriol (2012) 0.86
Resuscitation promoting factors: a family of microbial proteins in survival and resuscitation of dormant mycobacteria. Indian J Microbiol (2011) 0.85
Bacterial cell division regulation by Ser/Thr kinases: a structural perspective. Curr Protein Pept Sci (2012) 0.85
Dormant cells of Staphylococcus aureus are resuscitated by spent culture supernatant. PLoS One (2014) 0.84
Detection and Quantification of Differentially Culturable Tubercle Bacteria in Sputum from Tuberculosis Patients. Am J Respir Crit Care Med (2016) 0.83
ChiZ levels modulate cell division process in mycobacteria. Tuberculosis (Edinb) (2011) 0.81
Comparative genomics for mycobacterial peptidoglycan remodelling enzymes reveals extensive genetic multiplicity. BMC Microbiol (2014) 0.80
Mycobacterium tuberculosis RpfE crystal structure reveals a positively charged catalytic cleft. Protein Sci (2014) 0.79
Interaction of Mycobacterium tuberculosis Virulence Factor RipA with Chaperone MoxR1 Is Required for Transport through the TAT Secretion System. MBio (2016) 0.78
Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice. PLoS Pathog (2015) 0.78
Transcription of genes involved in sulfolipid and polyacyltrehalose biosynthesis of Mycobacterium tuberculosis in experimental latent tuberculosis infection. PLoS One (2013) 0.77
Structure of the stationary phase survival protein YuiC from B.subtilis. BMC Struct Biol (2015) 0.76
Resuscitation-promoting factors are cell wall-lytic enzymes with important roles in the germination and growth of Streptomyces coelicolor. J Bacteriol (2014) 0.76
NlpC/P60 domain-containing proteins of Mycobacterium avium subspecies paratuberculosis that differentially bind and hydrolyze peptidoglycan. Protein Sci (2016) 0.76
Regulated Expression Systems for Mycobacteria and Their Applications. Microbiol Spectr (2014) 0.75
Mycobacterial Growth. Cold Spring Harb Perspect Med (2015) 0.75
Developmental transcriptome of resting cell formation in Mycobacterium smegmatis. BMC Genomics (2016) 0.75
The RipA and RipB Peptidoglycan Endopeptidases Are Individually Nonessential to Mycobacterium smegmatis. J Bacteriol (2016) 0.75
Development of an In Vitro Assay for Detection of Drug-Induced Resuscitation-Promoting-Factor-Dependent Mycobacteria. Antimicrob Agents Chemother (2016) 0.75
An Amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase is required for mycobacterial cell division. Sci Rep (2017) 0.75
Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance. FEBS J (2016) 0.75
Insilico analysis and molecular docking of resuscitation promoting factor B (RpfB) protein of Mycobacterium tuberculosis. Bioinformation (2012) 0.75
Division site selection linked to inherited cell surface wave troughs in mycobacteria. Nat Microbiol (2017) 0.75
Genes required for mycobacterial growth defined by high density mutagenesis. Mol Microbiol (2003) 16.82
Cytokinesis in bacteria. Microbiol Mol Biol Rev (2003) 5.29
Structure, function, and biogenesis of the cell wall of Mycobacterium tuberculosis. Tuberculosis (Edinb) (2003) 4.16
Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor. Nucleic Acids Res (2005) 4.00
Diverse paths to midcell: assembly of the bacterial cell division machinery. Curr Biol (2005) 3.69
Premature targeting of cell division proteins to midcell reveals hierarchies of protein interactions involved in divisome assembly. Mol Microbiol (2006) 3.07
Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes. Genome Biol (2003) 3.02
The Escherichia coli amidase AmiC is a periplasmic septal ring component exported via the twin-arginine transport pathway. Mol Microbiol (2003) 3.01
Screening for synthetic lethal mutants in Escherichia coli and identification of EnvC (YibP) as a periplasmic septal ring factor with murein hydrolase activity. Mol Microbiol (2004) 2.42
Effects of multiple deletions of murein hydrolases on viability, septum cleavage, and sensitivity to large toxic molecules in Escherichia coli. J Bacteriol (2002) 2.29
SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis. Proc Natl Acad Sci U S A (2003) 2.18
The role of peptidoglycan in pathogenesis. Curr Opin Microbiol (2005) 1.71
Mutants of Mycobacterium tuberculosis lacking three of the five rpf-like genes are defective for growth in vivo and for resuscitation in vitro. Infect Immun (2005) 1.70
Muralytic activity of Micrococcus luteus Rpf and its relationship to physiological activity in promoting bacterial growth and resuscitation. Mol Microbiol (2006) 1.70
Septum enlightenment: assembly of bacterial division proteins. J Bacteriol (2006) 1.61
A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Mol Microbiol (2007) 1.59
Premature targeting of a cell division protein to midcell allows dissection of divisome assembly in Escherichia coli. Genes Dev (2005) 1.58
The rpf gene of Micrococcus luteus encodes an essential secreted growth factor. Mol Microbiol (2002) 1.56
Interference of Mycobacterium tuberculosis cell division by Rv2719c, a cell wall hydrolase. Mol Microbiol (2006) 1.54
Specific interaction of penicillin-binding proteins 3 and 7/8 with soluble lytic transglycosylase in Escherichia coli. J Biol Chem (1994) 1.53
The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes. Nat Struct Mol Biol (2005) 1.42
Deletion of the Mycobacterium tuberculosis resuscitation-promoting factor Rv1009 gene results in delayed reactivation from chronic tuberculosis. Infect Immun (2006) 1.40
Deletion of the gene encoding p60 in Listeria monocytogenes leads to abnormal cell division and loss of actin-based motility. Infect Immun (2003) 1.39
High resolution crystal structures of the Escherichia coli lytic transglycosylase Slt70 and its complex with a peptidoglycan fragment. J Mol Biol (1999) 1.34
A mycobacterial operon essential for virulence in vivo and invasion and intracellular persistence in macrophages. Infect Immun (2006) 1.31
Daughter cell separation by penicillin-binding proteins and peptidoglycan amidases in Escherichia coli. J Bacteriol (2006) 1.30
Identification of a novel peptidoglycan hydrolase CwlM in Mycobacterium tuberculosis. Biochim Biophys Acta (2004) 1.05
Genes required for mycobacterial growth defined by high density mutagenesis. Mol Microbiol (2003) 16.82
Genetic requirements for mycobacterial survival during infection. Proc Natl Acad Sci U S A (2003) 9.15
A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae. Proc Natl Acad Sci U S A (2002) 5.70
Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages. Proc Natl Acad Sci U S A (2005) 4.43
Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection. Science (2005) 3.49
Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing. Nat Biotechnol (2012) 3.39
Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science (2005) 3.28
Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis. Nat Rev Microbiol (2008) 2.97
Characterization of mycobacterial virulence genes through genetic interaction mapping. Proc Natl Acad Sci U S A (2006) 2.29
Construction of a mariner-based transposon for epitope-tagging and genomic targeting. Gene (2002) 2.15
Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition. Proc Natl Acad Sci U S A (2009) 2.10
Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms. J Immunol (2004) 2.08
Clinical practice. Latent tuberculosis infection in the United States. N Engl J Med (2011) 2.06
Bacterial growth and cell division: a mycobacterial perspective. Microbiol Mol Biol Rev (2008) 2.01
Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing. Cell (2013) 1.96
Systematic genetic nomenclature for type VII secretion systems. PLoS Pathog (2009) 1.96
Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis. Nat Genet (2013) 1.93
Twin RNA polymerase-associated proteins control virulence gene expression in Francisella tularensis. PLoS Pathog (2007) 1.92
Global assessment of genomic regions required for growth in Mycobacterium tuberculosis. PLoS Pathog (2012) 1.85
Letting sleeping dos lie: does dormancy play a role in tuberculosis? Annu Rev Microbiol (2010) 1.66
Mycobacterium tuberculosis ClpP1 and ClpP2 function together in protein degradation and are required for viability in vitro and during infection. PLoS Pathog (2012) 1.60
A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Mol Microbiol (2007) 1.59
Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates. Antimicrob Agents Chemother (2005) 1.55
Depletion of antibiotic targets has widely varying effects on growth. Proc Natl Acad Sci U S A (2011) 1.54
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212. Antimicrob Agents Chemother (2011) 1.51
The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria. Mol Microbiol (2004) 1.43
A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria. Sci Signal (2012) 1.41
High-resolution definition of the Vibrio cholerae essential gene set with hidden Markov model-based analyses of transposon-insertion sequencing data. Nucleic Acids Res (2013) 1.35
Ebola and quarantine. N Engl J Med (2014) 1.32
Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis. PLoS One (2013) 1.31
The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring. EMBO J (2012) 1.31
Entering the era of bacterial epigenomics with single molecule real time DNA sequencing. Curr Opin Microbiol (2013) 1.29
A defined O-antigen polysaccharide mutant of Francisella tularensis live vaccine strain has attenuated virulence while retaining its protective capacity. Infect Immun (2007) 1.27
Phthiocerol dimycocerosate transport is required for resisting interferon-gamma-independent immunity. J Infect Dis (2009) 1.26
Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria. PLoS Pathog (2010) 1.21
Function of a mycobacterial major facilitator superfamily pump requires a membrane-associated lipoprotein. J Bacteriol (2007) 1.19
Nitrile-inducible gene expression in mycobacteria. Tuberculosis (Edinb) (2008) 1.18
ESCRT factors restrict mycobacterial growth. Proc Natl Acad Sci U S A (2008) 1.15
Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2012) 1.13
para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. J Biol Chem (2013) 1.11
Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32. Proc Natl Acad Sci U S A (2013) 1.11
Ebola--an ongoing crisis. N Engl J Med (2014) 1.11
Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase . Biochemistry (2010) 1.09
Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin. Proc Natl Acad Sci U S A (2009) 1.08
Bacterial proteolytic complexes as therapeutic targets. Nat Rev Drug Discov (2012) 1.08
Transposon site hybridization in Mycobacterium tuberculosis. Methods Mol Biol (2008) 1.06
Mycobacterium tuberculosis Rv2224c modulates innate immune responses. Proc Natl Acad Sci U S A (2008) 1.05
Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance. Proc Natl Acad Sci U S A (2014) 1.05
Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase. Nucleic Acids Res (2010) 1.03
Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries. Bioinformatics (2013) 1.01
Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c. Proc Natl Acad Sci U S A (2014) 0.99
Feast or famine: the host-pathogen battle over amino acids. Cell Microbiol (2013) 0.99
HIV-1 replication is differentially regulated by distinct clinical strains of Mycobacterium tuberculosis. PLoS One (2009) 0.94
Mycobacterial Esx-3 requires multiple components for iron acquisition. MBio (2014) 0.93
Out of Africa--caring for patients with Ebola. N Engl J Med (2014) 0.92
Genomic analyses of microbial virulence. Curr Opin Microbiol (2002) 0.91
Differential requirement for PBP1a and PBP1b in in vivo and in vitro fitness of Vibrio cholerae. Infect Immun (2014) 0.91
The abyssomicin C family as in vitro inhibitors of Mycobacterium tuberculosis. Tuberculosis (Edinb) (2010) 0.89
Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria. PLoS Pathog (2013) 0.89
Bovine papillomavirus E7 oncoprotein inhibits anoikis. J Virol (2007) 0.89
Leveraging Advances in Tuberculosis Diagnosis and Treatment to Address Nontuberculous Mycobacterial Disease. Emerg Infect Dis (2016) 0.89
Once upon a time. . . improved intermittent therapy for tuberculosis--fact or fable? Am J Respir Crit Care Med (2005) 0.88
Chemical biology and bacteria: not simply a matter of life or death. Curr Opin Chem Biol (2006) 0.87
Ebola in West Africa at one year--from ignorance to fear to roadblocks. N Engl J Med (2014) 0.86
A new site-specific integration system for mycobacteria. Tuberculosis (Edinb) (2005) 0.86
Scaling down: a PCR-based method to efficiently screen for desired knockouts in a high density Mycobacterium tuberculosis picked mutant library. Tuberculosis (Edinb) (2006) 0.84
High-throughput sequencing enhanced phage display identifies peptides that bind mycobacteria. PLoS One (2013) 0.84
The complex relationship between mycobacteria and macrophages: it's not all bliss. Cell Host Microbe (2007) 0.83
New insights into TB physiology suggest untapped therapeutic opportunities. Immunol Rev (2015) 0.83
Characterization of submucosal lesions using optical coherence tomography in the rabbit subglottis. Arch Otolaryngol Head Neck Surg (2005) 0.83
Metabolic and bactericidal effects of targeted suppression of NadD and NadE enzymes in mycobacteria. MBio (2014) 0.83
The many roads to essential genes. Tuberculosis (Edinb) (2008) 0.82
New genetic approaches shed light on TB virulence. Trends Microbiol (2005) 0.81
Increased sulfate uptake by E. coli overexpressing the SLC26-related SulP protein Rv1739c from Mycobacterium tuberculosis. Comp Biochem Physiol A Mol Integr Physiol (2007) 0.81
Detecting genetic variability among different Mycobacterium tuberculosis strains using DNA microarrays technology. Tuberculosis (Edinb) (2006) 0.79
Relics of selection in the mycobacterial genome. Nat Genet (2010) 0.79
The open book of infectious diseases. Nat Med (2007) 0.78
The HIV-positive transplant donor--change born of necessity. N Engl J Med (2015) 0.77
Host transcription in active and latent tuberculosis. Genome Biol (2010) 0.76
Genetic Strategies for Identifying New Drug Targets. Microbiol Spectr (2014) 0.76
Tuberculosis. Advances in laboratory diagnosis and drug susceptibility testing. Am J Clin Pathol (2002) 0.76
Phage transposon mutagenesis. Methods Mol Biol (2009) 0.76
Correction: A Cytosine Methytransferase Modulates the Cell Envelope Stress Response in the Cholera Pathogen. PLoS Genet (2015) 0.75
Dividing oceans into pools: strategies for the global analysis of bacterial genes. Microbes Infect (2006) 0.75
Audio Interview: Understanding the Omicron Variant of SARS-CoV-2. N Engl J Med (2022) 0.75
We Can Do Better - Improving Outcomes in the Midst of an Emergency. N Engl J Med (2017) 0.75
Audio Interview: Covid-19 and Contact Tracing. N Engl J Med (2020) 0.75
Bacterial genomics and vaccine design. Expert Rev Vaccines (2003) 0.75
Audio Interview: Operation Warp Speed and Covid-19. N Engl J Med (1) 0.75
Covid-19 - The Search for Effective Therapy. N Engl J Med (2020) 0.75