Jacopo Sgrignani

Author PubWeight™ 0.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural investigation of the 7-chloro-3-hydroxy-1H-quinazoline-2,4-dione scaffold to obtain AMPA and kainate receptor selective antagonists. Synthesis, pharmacological, and molecular modeling studies. J Med Chem 2006 0.84
2 Synthesis and biological evaluation of novel 9-heteroaryl substituted 7-chloro-4,5-dihydro-4-oxo-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylates (TQX) as (R,S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) receptor antagonists. Chem Pharm Bull (Tokyo) 2008 0.78
3 Tuning the activity of Zn(II) complexes in DNA cleavage: clues for design of new efficient metallo-hydrolases. Inorg Chem 2008 0.77
4 Structural role of uracil DNA glycosylase for the recognition of uracil in DNA duplexes. Clues from atomistic simulations. J Chem Inf Model 2013 0.75
5 Structural and dynamic properties of monoclonal antibodies immobilized on CNTs: a computational study. Chemistry 2013 0.75
6 Enzymatic and Inhibition Mechanism of Human Aromatase (CYP19A1) Enzyme. A Computational Perspective from QM/MM and Classical Molecular Dynamics Simulations. Mini Rev Med Chem 2016 0.75