Published in J Thromb Haemost on May 14, 2008
cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action. Pharmacol Rev (2010) 3.27
Signaling during platelet adhesion and activation. Arterioscler Thromb Vasc Biol (2010) 2.43
Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation. Blood (2011) 2.27
Endothelial nitric oxide synthase in red blood cells: key to a new erythrocrine function? Redox Biol (2014) 2.18
Thrombin and collagen induce a feedback inhibitory signaling pathway in platelets involving dissociation of the catalytic subunit of protein kinase A from an NFkappaB-IkappaB complex. J Biol Chem (2010) 1.47
Nucleotide-binding oligomerization domain 2 receptor is expressed in platelets and enhances platelet activation and thrombosis. Circulation (2015) 1.12
An important role of the SRC family kinase Lyn in stimulating platelet granule secretion. J Biol Chem (2010) 1.00
Akt signaling in platelets and thrombosis. Expert Rev Hematol (2010) 0.99
Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in platelets. J Biol Chem (2012) 0.99
Thrombospondin-1 and angiotensin II inhibit soluble guanylyl cyclase through an increase in intracellular calcium concentration. Biochemistry (2011) 0.89
Platelet aggregation responses are critically regulated in vivo by endogenous nitric oxide but not by endothelial nitric oxide synthase. Br J Pharmacol (2009) 0.88
The anti-aggregating effect of BAY 41-2272, a stimulator of soluble guanylyl cyclase, requires the presence of nitric oxide. Br J Pharmacol (2010) 0.85
Abnormal platelet aggregation in idiopathic pulmonary arterial hypertension: role of nitric oxide. Am J Physiol Lung Cell Mol Physiol (2012) 0.85
Insulin, insulin resistance, and platelet signaling in diabetes. Diabetes Care (2009) 0.82
Platelet content of nitric oxide synthase 3 phosphorylated at Serine 1177 is associated with the functional response of platelets to aspirin. PLoS One (2013) 0.80
Impaired platelet activation and cAMP homeostasis in MRP4-deficient mice. Blood (2015) 0.79
Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets. Arterioscler Thromb Vasc Biol (2016) 0.78
Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis. Exp Hematol (2012) 0.78
Effect of storage on levels of nitric oxide metabolites in platelet preparations. Transfusion (2012) 0.77
eNOS, iNOS or no NOS, that is the question! J Thromb Haemost (2008) 0.77
Echicetin coated polystyrene beads: a novel tool to investigate GPIb-specific platelet activation and aggregation. PLoS One (2014) 0.75
Glucagon-Like Peptide 1 Receptor Activation and Platelet Function: Beyond Glycemic Control. Diabetes (2016) 0.75
PKC and AKT Modulate cGMP/PKG Signaling Pathway on Platelet Aggregation in Experimental Sepsis. PLoS One (2015) 0.75
NO at work. Cell (1994) 5.07
Response of naïve and memory CD8+ T cells to antigen stimulation in vivo. Nat Immunol (2000) 4.08
The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins. EMBO J (1995) 3.69
cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets. J Biol Chem (1994) 2.95
Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture. Proc Natl Acad Sci U S A (1980) 2.84
Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle. J Biol Chem (2000) 2.77
A focal adhesion factor directly linking intracellularly motile Listeria monocytogenes and Listeria ivanovii to the actin-based cytoskeleton of mammalian cells. EMBO J (1995) 2.68
The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts. EMBO J (1992) 2.58
The nitric oxide and cGMP signal transduction system: regulation and mechanism of action. Biochim Biophys Acta (1993) 2.54
The randomized shortened dental arch study: tooth loss. J Dent Res (2010) 2.35
Activation of the contact-phase system on bacterial surfaces--a clue to serious complications in infectious diseases. Nat Med (1998) 2.32
The EVH2 domain of the vasodilator-stimulated phosphoprotein mediates tetramerization, F-actin binding, and actin bundle formation. J Biol Chem (1999) 2.31
Ca2+ current is regulated by cyclic GMP-dependent protein kinase in mammalian cardiac myocytes. Proc Natl Acad Sci U S A (1991) 2.15
Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody. J Biol Chem (1998) 2.14
Limitations of sniff nasal pressure as an outcome measurement in amyotrophic lateral sclerosis patients in a clinical trial. Respiration (2012) 2.02
Assembly of human contact phase proteins and release of bradykinin at the surface of curli-expressing Escherichia coli. Mol Microbiol (1996) 1.97
The serum protein alpha2-HS glycoprotein/fetuin inhibits apatite formation in vitro and in mineralizing calvaria cells. A possible role in mineralization and calcium homeostasis. J Biol Chem (1996) 1.94
Theophylline metabolism by the rat liver microsomal system. J Pharmacol Exp Ther (1976) 1.89
Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP. EMBO J (1995) 1.88
The bacterial actin nucleator protein ActA of Listeria monocytogenes contains multiple binding sites for host microfilament proteins. Curr Biol (1995) 1.83
Stoichiometric and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP- and cAMP-elevating vasodilators. J Biol Chem (1990) 1.81
Distinct and specific functions of cGMP-dependent protein kinases. Trends Biochem Sci (1997) 1.80
Streptococcal cysteine proteinase releases kinins: a virulence mechanism. J Exp Med (1996) 1.77
Identification, purification, and characterization of a zyxin-related protein that binds the focal adhesion and microfilament protein VASP (vasodilator-stimulated phosphoprotein). Proc Natl Acad Sci U S A (1995) 1.74
Treatment of patent ductus arteriosus with ibuprofen. Arch Dis Child Fetal Neonatal Ed (1997) 1.73
Pleiotropic changes controlled by the pre-T-cell receptor. Curr Opin Immunol (1999) 1.71
Nomenclature and classification of the proteins homologous with the cysteine-proteinase inhibitor chicken cystatin. Biochem J (1986) 1.71
The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family. Mol Cell Biol (1994) 1.67
Cloning and targeted deletion of the mouse fetuin gene. J Biol Chem (1997) 1.64
Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction. Circ Res (2000) 1.60
The multiligand-binding protein gC1qR, putative C1q receptor, is a mitochondrial protein. J Immunol (1998) 1.58
Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-dependent protein kinases. J Biol Chem (2000) 1.55
Megakaryocyte hyperplasia and enhanced agonist-induced platelet activation in vasodilator-stimulated phosphoprotein knockout mice. Proc Natl Acad Sci U S A (1999) 1.50
YC-1 potentiates nitric oxide- and carbon monoxide-induced cyclic GMP effects in human platelets. Mol Pharmacol (1998) 1.49
Regulation of the cellular and subcellular concentrations and distribution of cyclic nucleotide-dependent protein kinases. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 1.49
Receptor phosphorylation does not mediate cross talk between muscarinic M(3) and bradykinin B(2) receptors. Am J Physiol (1999) 1.49
Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition. Eur J Biochem (1994) 1.48
Purification of a vasodilator-regulated phosphoprotein from human platelets. Eur J Biochem (1989) 1.48
Insulin inhibition of platelet-endothelial interaction is mediated by insulin effects on endothelial cells without direct effects on platelets. J Thromb Haemost (2008) 1.47
Actin-based motility: stop and go with Ena/VASP proteins. Trends Biochem Sci (2001) 1.45
VASP interaction with vinculin: a recurring theme of interactions with proline-rich motifs. FEBS Lett (1996) 1.44
Differential regulation of distinct types of gap junction channels by similar phosphorylating conditions. Mol Biol Cell (1995) 1.42
KT5823 inhibits cGMP-dependent protein kinase activity in vitro but not in intact human platelets and rat mesangial cells. J Biol Chem (2000) 1.41
Heterogeneous distribution of the cAMP receptor protein RII in the nervous system: evidence for its intracellular accumulation on microtubules, microtubule-organizing centers, and in the area of the Golgi complex. J Cell Biol (1986) 1.41
Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets. Proc Natl Acad Sci U S A (1992) 1.40
Vasodilator-stimulated protein phosphorylation in platelets is mediated by cAMP- and cGMP-dependent protein kinases. Eur J Biochem (1987) 1.40
Frozen tissue sections as an experimental system to reveal specific binding sites for the regulatory subunit of type II cAMP-dependent protein kinase in neurons. Proc Natl Acad Sci U S A (1982) 1.40
Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity. EMBO J (2000) 1.40
Identification, characterization, and quantitative measurement of cyclic AMP receptor proteins in cytosol of various tissues using a photoaffinity ligand. J Biol Chem (1977) 1.40
Von Willebrand disease caused by compound heterozygosity for p.r854q and p.r760c: diagnostic and therapeutic implications. Haemophilia (2010) 1.39
Molecular cloning and predicted full-length amino acid sequence of the type I beta isozyme of cGMP-dependent protein kinase from human placenta. Tissue distribution and developmental changes in rat. FEBS Lett (1989) 1.39
Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease. Neurology (2008) 1.39
Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains. Mol Biol Cell (1998) 1.38
Fatal complication of desmopressin. Lancet (1995) 1.38
Isolation and characterization of the kininogen-binding protein p33 from endothelial cells. Identity with the gC1q receptor. J Biol Chem (1996) 1.35
Physiological role of cGMP and cGMP-dependent protein kinase in the cardiovascular system. Rev Physiol Biochem Pharmacol (1989) 1.35
Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B(2) receptors. J Exp Med (2000) 1.35
Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo. Neuropharmacology (1995) 1.34
Immunohistochemical localization of cyclic GMP-dependent protein kinase in mammalian brain. Proc Natl Acad Sci U S A (1981) 1.34
Taming platelets with cyclic nucleotides. Biochem Pharmacol (2001) 1.34
Immunomodulatory properties of cystatins. Cell Mol Life Sci (2002) 1.34
Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I. J Biol Chem (2000) 1.33
Neonatal screening for hearing disorders in infants at risk: incidence, risk factors, and follow-up. Pediatrics (1999) 1.32
Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II. Proc Natl Acad Sci U S A (1994) 1.31
Demonstration of cGMP-dependent protein kinase and cGMP-dependent phosphorylation in cell-free extracts of platelets. Eur J Biochem (1986) 1.31
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation. Proc Natl Acad Sci U S A (1998) 1.31
Hypertension does not account for the accelerated atherosclerosis and development of aneurysms in male apolipoprotein e/endothelial nitric oxide synthase double knockout mice. Circulation (2001) 1.31
High-affinity binding of the regulatory subunit (RII) of cAMP-dependent protein kinase to microtubule-associated and other cellular proteins. Proc Natl Acad Sci U S A (1984) 1.30
NOSIP, a novel modulator of endothelial nitric oxide synthase activity. FASEB J (2001) 1.29
Ontogeny of synaptic phosphoproteins in brain. Proc Natl Acad Sci U S A (1978) 1.29
Vasopressin V2 receptor expression along rat, mouse, and human renal epithelia with focus on TAL. Am J Physiol Renal Physiol (2007) 1.28
Identification of a plasminogen-binding motif in PAM, a bacterial surface protein. Mol Microbiol (1995) 1.27
Autoantibodies against the angiotensin receptor (AT1) in patients with hypertension. J Hypertens (2000) 1.26
Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3',5'-monophosphorothioates. FEBS Lett (1990) 1.25
Effects of in vivo nitroglycerin treatment on activity and expression of the guanylyl cyclase and cGMP-dependent protein kinase and their downstream target vasodilator-stimulated phosphoprotein in aorta. Circulation (2001) 1.24
A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function. Mol Psychiatry (2006) 1.24
Immunological distinction between guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases. J Biol Chem (1980) 1.22
The impact of maternal education on intrauterine growth: a comparison of former West and East Germany. Int J Epidemiol (2001) 1.22
Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects. Naunyn Schmiedebergs Arch Pharmacol (1998) 1.22
Recognition signal for C-mannosylation of Trp-7 in RNase 2 consists of sequence Trp-x-x-Trp. Mol Biol Cell (1998) 1.21
Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein kinase II. J Biol Chem (1995) 1.20
Analysis of the functional role of cGMP-dependent protein kinase in intact human platelets using a specific activator 8-para-chlorophenylthio-cGMP. Biochem Pharmacol (1992) 1.17
Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator. J Clin Invest (1995) 1.17
Molecular cloning, cDNA structure, and regulation of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovarian granulosa cells. J Biol Chem (1986) 1.17