Published in Angew Chem Int Ed Engl on January 01, 2008
Rhodium-catalyzed C-C bond formation via heteroatom-directed C-H bond activation. Chem Rev (2010) 3.89
Scope of the Suzuki-Miyaura cross-coupling reactions of potassium heteroaryltrifluoroborates. J Org Chem (2009) 2.54
Rh(I)-catalyzed direct arylation of pyridines and quinolines. J Am Chem Soc (2008) 1.18
A general solution for the 2-pyridyl problem. Angew Chem Int Ed Engl (2012) 1.17
A versatile catalyst system for Suzuki-Miyaura cross-coupling reactions of C(sp(2))-tosylates and mesylates. Org Lett (2009) 1.14
General method for synthesis of 2-heterocyclic N-methyliminodiacetic acid boronates. Org Lett (2010) 1.09
Mild and general conditions for negishi cross-coupling enabled by the use of palladacycle precatalysts. Angew Chem Int Ed Engl (2012) 1.06
Palladium-catalyzed 1,1-difunctionalization of ethylene. J Am Chem Soc (2012) 1.01
Synthesis of solid 2-pyridylzinc reagents and their application in Negishi reactions. Org Lett (2013) 0.96
A general method for Suzuki-Miyaura coupling reactions using lithium triisopropyl borates. Org Lett (2012) 0.86
Development of a palladium-catalyzed decarboxylative cross-coupling of (2-azaaryl)carboxylates with aryl halides. Tetrahedron (2013) 0.77
Selective and Serial Suzuki-Miyaura Reactions of Polychlorinated Aromatics with Alkyl Pinacol Boronic Esters. Org Lett (2016) 0.75
Rh(I)-catalyzed direct arylation of azines. J Org Chem (2010) 0.75
Pyridine sulfinates as general nucleophilic coupling partners in palladium-catalyzed cross-coupling reactions with aryl halides. Chem Sci (2017) 0.75
Catalysts for Suzuki-Miyaura coupling processes: scope and studies of the effect of ligand structure. J Am Chem Soc (2005) 4.73
Highly efficient monophosphine-based catalyst for the palladium-catalyzed suzuki-miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters. J Am Chem Soc (2007) 2.29
Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of potassium aryl- and heteroaryltrifluoroborates. J Org Chem (2003) 2.13
Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). J Med Chem (2007) 1.61
An improved protocol for the preparation of 3-pyridyl- and some arylboronic acids. J Org Chem (2002) 1.18
Efficient aryl-(hetero)aryl coupling by activation of C-Cl and C-F bonds using nickel complexes of air-stable phosphine oxides. Angew Chem Int Ed Engl (2005) 1.00
The First Phosphine Oxide Ligand Precursors for Transition Metal Catalyzed Cross-Coupling Reactions: C-C, C-N, and C-S Bond Formation on Unactivated Aryl Chlorides. Angew Chem Int Ed Engl (2001) 0.97
Total synthesis of (+/-)-cytisine. Org Lett (2000) 0.89
Air-stable PinP(O)H as preligand for palladium-catalyzed Kumada couplings of unactivated tosylates. Org Lett (2006) 0.88
Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. J Med Chem (2007) 0.88
Palladium-phosphinous acid-catalyzed NaOH-promoted cross-coupling reactions of arylsiloxanes with aryl chlorides and bromides in water. Org Lett (2004) 0.86
Efficient Stille cross-coupling reaction using aryl chlorides or bromides in water. J Org Chem (2003) 0.84
Identification of non-furan containing A2A antagonists using database mining and molecular similarity approaches. Bioorg Med Chem Lett (2006) 0.82
Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists--Increasing selectivity over hERG. Bioorg Med Chem Lett (2006) 0.81
Arylamine based cathepsin K inhibitors: investigating P3 heterocyclic substituents. Bioorg Med Chem (2006) 0.81
Palladium-catalyzed chemoselective cross-coupling of acyl chlorides and organostannanes. J Org Chem (2005) 0.80
Catalysts for Suzuki-Miyaura coupling processes: scope and studies of the effect of ligand structure. J Am Chem Soc (2005) 4.73
Formation of ArF from LPdAr(F): catalytic conversion of aryl triflates to aryl fluorides. Science (2009) 4.13
Biaryl phosphane ligands in palladium-catalyzed amination. Angew Chem Int Ed Engl (2008) 3.70
Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions employing dialkylbiaryl phosphine ligands. Acc Chem Res (2008) 3.39
A highly active catalyst for Pd-catalyzed amination reactions: cross-coupling reactions using aryl mesylates and the highly selective monoarylation of primary amines using aryl chlorides. J Am Chem Soc (2008) 3.32
The palladium-catalyzed trifluoromethylation of aryl chlorides. Science (2010) 2.85
A new palladium precatalyst allows for the fast Suzuki-Miyaura coupling reactions of unstable polyfluorophenyl and 2-heteroaryl boronic acids. J Am Chem Soc (2010) 2.73
An extremely active catalyst for the Negishi cross-coupling reaction. J Am Chem Soc (2004) 2.68
Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (2013) 2.61
A new class of easily activated palladium precatalysts for facile C-N cross-coupling reactions and the low temperature oxidative addition of aryl chlorides. J Am Chem Soc (2008) 2.61
Dialkylbiaryl Phosphines in Pd-Catalyzed Amination: A User's Guide. Chem Sci (2011) 2.60
Expanding Pd-catalyzed C-N bond-forming processes: the first amidation of aryl sulfonates, aqueous amination, and complementarity with Cu-catalyzed reactions. J Am Chem Soc (2003) 2.41
Highly efficient monophosphine-based catalyst for the palladium-catalyzed suzuki-miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters. J Am Chem Soc (2007) 2.29
A general and efficient copper catalyst for the amidation of aryl halides. J Am Chem Soc (2002) 2.17
Monodentate phosphines provide highly active catalysts for Pd-catalyzed C-N bond-forming reactions of heteroaromatic halides/amines and (H)N-heterocycles. Angew Chem Int Ed Engl (2006) 1.98
Design and Preparation of New Palladium Precatalysts for C-C and C-N Cross-Coupling Reactions. Chem Sci (2013) 1.96
Palladium-catalyzed borylation of aryl chlorides: scope, applications, and computational studies. Angew Chem Int Ed Engl (2007) 1.94
Copper-catalyzed coupling of amides and carbamates with vinyl halides. Org Lett (2003) 1.88
Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. Science (2013) 1.85
An improved catalyst for the asymmetric arylation of ketone enolates. J Am Chem Soc (2002) 1.84
Pd-catalyzed amidation of aryl chlorides using monodentate biaryl phosphine ligands: a kinetic, computational, and synthetic investigation. J Am Chem Soc (2007) 1.84
A rationally designed universal catalyst for Suzuki-Miyaura coupling processes. Angew Chem Int Ed Engl (2004) 1.82
An integrated microreactor system for self-optimization of a Heck reaction: from micro- to mesoscale flow systems. Angew Chem Int Ed Engl (2010) 1.77
Significantly improved method for the pd-catalyzed coupling of phenols with aryl halides: understanding ligand effects. Angew Chem Int Ed Engl (2006) 1.76
Water-mediated catalyst preactivation: an efficient protocol for C-N cross-coupling reactions. Org Lett (2008) 1.60
The first general palladium catalyst for the Suzuki-Miyaura and carbonyl enolate coupling of aryl arenesulfonates. J Am Chem Soc (2003) 1.55
An Efficient System For the Pd-Catalyzed Cross-Coupling of Amides and Aryl Chlorides. Tetrahedron (2009) 1.54
Negishi coupling of secondary alkylzinc halides with aryl bromides and chlorides. J Am Chem Soc (2009) 1.53
The selective reaction of aryl halides with KOH: synthesis of phenols, aromatic ethers, and benzofurans. J Am Chem Soc (2006) 1.53
Room temperature aryl trifluoromethylation via copper-mediated oxidative cross-coupling. J Org Chem (2011) 1.52
Pd-catalyzed intermolecular amidation of aryl halides: the discovery that xantphos can be trans-chelating in a palladium complex. J Am Chem Soc (2002) 1.52
Continuous-flow synthesis of biaryls enabled by multistep solid-handling in a lithiation/borylation/Suzuki-Miyaura cross-coupling sequence. Angew Chem Int Ed Engl (2011) 1.52
An air and thermally stable one- component catalyst for the amination of aryl chlorides. Org Lett (2003) 1.47
Evidence for in situ catalyst modification during the Pd-catalyzed conversion of aryl triflates to aryl fluorides. J Am Chem Soc (2011) 1.47
C-H functionalization/C-N bond formation: copper-catalyzed synthesis of benzimidazoles from amidines. Angew Chem Int Ed Engl (2008) 1.47
Pd-catalyzed conversion of aryl chlorides, triflates, and nonaflates to nitroaromatics. J Am Chem Soc (2009) 1.47
Palladium-Catalyzed Coupling of Functionalized Primary and Secondary Amines with Aryl and Heteroaryl Halides: Two Ligands Suffice in Most Cases. Chem Sci (2011) 1.46
Twofold C-H functionalization: palladium-catalyzed ortho arylation of anilides. Org Lett (2008) 1.46
Electronic effects on the selectivity of pd-catalyzed C-N bond-forming reactions using biarylphosphine ligands: the competitive roles of amine binding and acidity. Angew Chem Int Ed Engl (2007) 1.45
An improved system for the palladium-catalyzed borylation of aryl halides with pinacol borane. J Org Chem (2008) 1.45
Copper-catalyzed halogen exchange in aryl halides: an aromatic Finkelstein reaction. J Am Chem Soc (2002) 1.43
Nickel-BINAP catalyzed enantioselective alpha-arylation of alpha-substituted gamma-butyrolactones. J Am Chem Soc (2002) 1.41
On the role of metal contaminants in catalyses with FeCl3. Angew Chem Int Ed Engl (2009) 1.41
Palladium-catalyzed enantioselective alpha-arylation and alpha-vinylation of oxindoles facilitated by an axially chiral P-stereogenic ligand. J Am Chem Soc (2009) 1.41
Enantio- and regioselective CuH-catalyzed hydroamination of alkenes. J Am Chem Soc (2013) 1.39
Highly selective room-temperature copper-catalyzed C-N coupling reactions. J Am Chem Soc (2006) 1.38
Synthesis and application of palladium precatalysts that accommodate extremely bulky di-tert-butylphosphino biaryl ligands. Org Lett (2013) 1.38
The copper-catalyzed N-arylation of indoles. J Am Chem Soc (2002) 1.36
Computational explorations of mechanisms and ligand-directed selectivities of copper-catalyzed Ullmann-type reactions. J Am Chem Soc (2010) 1.36
Efficient pd-catalyzed amination of heteroaryl halides. Org Lett (2005) 1.35
Copper-diamine-catalyzed N-arylation of pyrroles, pyrazoles, indazoles, imidazoles, and triazoles. J Org Chem (2004) 1.34
Improved functional group compatibility in the palladium-catalyzed synthesis of aryl amines. Org Lett (2002) 1.33
A highly active catalyst for Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds. Angew Chem Int Ed Engl (2006) 1.33
Pd-catalyzed nucleophilic fluorination of aryl bromides. J Am Chem Soc (2014) 1.28
Selective palladium-catalyzed arylation of ammonia: synthesis of anilines as well as symmetrical and unsymmetrical di- and triarylamines. J Am Chem Soc (2007) 1.28
Synthesis of substituted oxindoles from alpha-chloroacetanilides via palladium-catalyzed C[bond]H functionalization. J Am Chem Soc (2003) 1.27
An efficient process for pd-catalyzed C-N cross-coupling reactions of aryl iodides: insight into controlling factors. J Am Chem Soc (2009) 1.27
An improved Cu-based catalyst system for the reactions of alcohols with aryl halides. J Org Chem (2007) 1.26
Catalytic enantioselective conjugate reduction of lactones and lactams. J Am Chem Soc (2003) 1.26
Pd-catalyzed Kumada-Corriu cross-coupling reactions at low temperatures allow the use of Knochel-type Grignard reagents. J Am Chem Soc (2007) 1.26
Pd-catalyzed N-arylation of secondary acyclic amides: catalyst development, scope, and computational study. J Am Chem Soc (2009) 1.25
Copper-catalyzed coupling of aryl iodides with aliphatic alcohols. Org Lett (2002) 1.25
General catalysts for the Suzuki-Miyaura and Sonogashira coupling reactions of aryl chlorides and for the coupling of challenging substrate combinations in water. Angew Chem Int Ed Engl (2005) 1.24
Use of tunable ligands allows for intermolecular Pd-catalyzed C--O bond formation. J Am Chem Soc (2005) 1.24
Combined C-H functionalization/C-N bond formation route to carbazoles. J Am Chem Soc (2005) 1.23
Palladium-catalyzed monoarylation of nitroalkanes. J Org Chem (2002) 1.22
A bulky biaryl phosphine ligand allows for palladium-catalyzed amidation of five-membered heterocycles as electrophiles. Angew Chem Int Ed Engl (2012) 1.22
Insights into amine binding to biaryl phosphine palladium oxidative addition complexes and reductive elimination from biaryl phosphine arylpalladium amido complexes via density functional theory. J Am Chem Soc (2007) 1.22
Copper-catalyzed asymmetric conjugate reduction as a route to novel beta-azaheterocyclic acid derivatives. Proc Natl Acad Sci U S A (2004) 1.21
Palladium-catalyzed carbonylation of aryl tosylates and mesylates. J Am Chem Soc (2008) 1.20
A multiligand based Pd catalyst for C-N cross-coupling reactions. J Am Chem Soc (2010) 1.20
Insights into the origin of high activity and stability of catalysts derived from bulky, electron-rich monophosphinobiaryl ligands in the Pd-catalyzed C-N bond formation. J Am Chem Soc (2003) 1.19
N- versus O-arylation of aminoalcohols: orthogonal selectivity in copper-based catalysts. J Am Chem Soc (2007) 1.19
Accelerating palladium-catalyzed C-F bond formation: use of a microflow packed-bed reactor. Angew Chem Int Ed Engl (2011) 1.18
Copper-catalyzed coupling of alkylamines and aryl iodides: an efficient system even in an air atmosphere. Org Lett (2002) 1.18
Completely N1-selective palladium-catalyzed arylation of unsymmetric imidazoles: application to the synthesis of nilotinib. J Am Chem Soc (2011) 1.16
A general method for the direct alpha-arylation of aldehydes with aryl bromides and chlorides. Angew Chem Int Ed Engl (2007) 1.16
Mechanistic studies on the copper-catalyzed N-arylation of amides. J Am Chem Soc (2009) 1.15
A single phosphine ligand allows palladium-catalyzed intermolecular C-O bond formation with secondary and primary alcohols. Angew Chem Int Ed Engl (2011) 1.15
Diamine Ligands in Copper-Catalyzed Reactions. Chem Sci (2010) 1.15
Copper-catalyzed N-arylation of imidazoles and benzimidazoles. J Org Chem (2007) 1.14
A versatile catalyst system for Suzuki-Miyaura cross-coupling reactions of C(sp(2))-tosylates and mesylates. Org Lett (2009) 1.14
The role of chelating diamine ligands in the goldberg reaction: a kinetic study on the copper-catalyzed amidation of aryl iodides. J Am Chem Soc (2005) 1.13
Orthogonal Cu- and Pd-based catalyst systems for the O- and N-arylation of aminophenols. J Am Chem Soc (2009) 1.13
Mild and efficient copper-catalyzed amination of aryl bromides with primary alkylamines. Org Lett (2003) 1.12
Palladium-catalyzed conversion of aryl and vinyl triflates to bromides and chlorides. J Am Chem Soc (2010) 1.11
Conjugate reduction of alpha,beta-unsaturated carbonyl compounds catalyzed by a copper carbene complex. Org Lett (2003) 1.10
A general, efficient, and inexpensive catalyst system for the coupling of aryl iodides and thiols. Org Lett (2002) 1.09
Domino cu-catalyzed C--N coupling/hydroamidation: a highly efficient synthesis of nitrogen heterocycles. Angew Chem Int Ed Engl (2006) 1.09
Reevaluation of the mechanism of the amination of aryl halides catalyzed by BINAP-ligated palladium complexes. J Am Chem Soc (2006) 1.09
Asymmetric palladium-catalyzed intramolecular alpha-arylation of aldehydes. Angew Chem Int Ed Engl (2008) 1.08
Development of an air-stable nickel precatalyst for the amination of aryl chlorides, sulfamates, mesylates, and triflates. Org Lett (2013) 1.07
Ligand-controlled palladium-catalyzed regiodivergent Suzuki-Miyaura cross-coupling of allylboronates and aryl halides. J Am Chem Soc (2013) 1.07
A highly active Suzuki catalyst for the synthesis of sterically hindered biaryls: novel ligand coordination. J Am Chem Soc (2002) 1.07
Pd-catalyzed cross-coupling reactions of amides and aryl mesylates. Org Lett (2010) 1.06
Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs. Proc Natl Acad Sci U S A (2008) 1.06
Copper-catalyzed vinylation of hydrazides. A regioselective entry to highly substituted pyrroles. Org Lett (2007) 1.06
Mild and general conditions for negishi cross-coupling enabled by the use of palladacycle precatalysts. Angew Chem Int Ed Engl (2012) 1.06