Published in Crit Care on May 14, 2008
Strategies to optimize analgesia and sedation. Crit Care (2008) 1.08
Decreasing severe pain and serious adverse events while moving intensive care unit patients: a prospective interventional study (the NURSE-DO project). Crit Care (2013) 0.94
Midazolam and propofol used alone or sequentially for long-term sedation in critically ill, mechanically ventilated patients: a prospective, randomized study. Crit Care (2014) 0.85
Analgesia and sedation in the intensive care unit: an overview of the issues. Crit Care (2008) 0.80
Evaluating the effects of dexmedetomidine compared to propofol as adjunctive therapy in patients with alcohol withdrawal. Clin Pharmacol (2014) 0.78
Utilization patterns of central nervous system drugs: A cross-sectional study among the critically ill patients. J Neurosci Rural Pract (2011) 0.77
The validation and inter-rater reliability of the Serbian translation of the Richmond agitation and sedation scale in post anesthesia care unit patients. Hippokratia (2016) 0.75
A retrospective analysis of determinants of self-extubation in a tertiary care intensive care unit. J Emerg Trauma Shock (2013) 0.75
Off-Label Use of Dexmedetomidine for the Treatment of Delirium in the Intensive Care Unit. P T (2016) 0.75
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med (2000) 11.54
Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med (2002) 9.74
Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. Anesthesiology (2006) 4.03
Sedative and analgesic practice in the intensive care unit: the results of a European survey. Br J Anaesth (2001) 2.75
Sedation in the intensive care unit: a systematic review. JAMA (2000) 2.65
Propylene glycol toxicity: a severe iatrogenic illness in ICU patients receiving IV benzodiazepines: a case series and prospective, observational pilot study. Chest (2005) 2.31
A double-blind, randomized comparison of i.v. lorazepam versus midazolam for sedation of ICU patients via a pharmacologic model. Anesthesiology (2001) 2.25
Isoflurane and propofol for long-term sedation in the intensive care unit. A crossover study. Anaesthesia (1992) 2.13
Isoflurane for prolonged sedation in the intensive care unit; efficacy and safety. Intensive Care Med (1992) 2.06
Isoflurane compared with midazolam for sedation in the intensive care unit. BMJ (1989) 2.02
Epidural analgesia improves outcome after multiple rib fractures. Surgery (2004) 1.84
The role of the alpha2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit. J Intensive Care Med (2004) 1.72
A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unit. Intensive Care Med (2002) 1.65
Morphine-6-glucuronide, a potent mu agonist. Life Sci (1987) 1.55
Remifentanil versus morphine analgesia and sedation for mechanically ventilated critically ill patients: a randomized double blind study. Anesthesiology (2004) 1.37
Remifentanil versus fentanyl for analgesia based sedation to provide patient comfort in the intensive care unit: a randomized, double-blind controlled trial [ISRCTN43755713]. Crit Care (2003) 1.33
Remifentanil update: clinical science and utility. CNS Drugs (2004) 1.33
Prolonged isoflurane sedation of intensive care unit patients with the Anesthetic Conserving Device. Crit Care Med (2004) 1.11
Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment. Crit Care (2003) 1.11
Effects of perioperative central neuraxial analgesia on outcome after coronary artery bypass surgery: a meta-analysis. Anesthesiology (2004) 1.11
Sedation and analgesia in the intensive care unit: evaluating the role of dexmedetomidine. Am J Health Syst Pharm (2007) 1.07
Pharmacokinetics of remifentanil and its major metabolite, remifentanil acid, in ICU patients with renal impairment. Br J Anaesth (2004) 1.04
Propofol vs midazolam for ICU sedation : a Canadian multicenter randomized trial. Chest (2001) 1.02
A comparison of hypnotic and analgesic based sedation in a general intensive care unit. Br J Anaesth (2007) 1.01
Propofol dosing regimens for ICU sedation based upon an integrated pharmacokinetic-pharmacodynamic model. Anesthesiology (2001) 1.00
[Using epidural anesthesia in patients with acute pancreatitis--prospective study of 121 patients]. Anaesthesiol Reanim (2002) 0.99
The benefits of adding epidural analgesia to general anesthesia: a metaanalysis. J Anesth (2006) 0.94
Clinical pharmacology of flumazenil. Eur J Anaesthesiol Suppl (1988) 0.93
AnaConDa reflection filter: bench and patient evaluation of safety and volatile anesthetic conservation. Anesth Analg (2007) 0.89
Survey of epidural analgesia management in general intensive care units in England. Acta Anaesthesiol Scand (2002) 0.83
The extent of metabolism of inhaled anesthetics in humans. Anesthesiology (1986) 0.82
Morphine-6-glucuronide is more mu-selective and potent in analgesic tests than morphine. Prog Clin Biol Res (1990) 0.82
Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial. Am J Respir Crit Care Med (2010) 5.41
Neutrophil gelatinase-associated lipocalin at ICU admission predicts for acute kidney injury in adult patients. Am J Respir Crit Care Med (2010) 4.61
Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Crit Care Med (2004) 4.24
Association between blood lactate levels, Sequential Organ Failure Assessment subscores, and 28-day mortality during early and late intensive care unit stay: a retrospective observational study. Crit Care Med (2009) 3.83
Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med (2014) 3.37
Euthanasia in intensive care: a 56-year-old man with a pontine hemorrhage resulting in a locked-in syndrome. Crit Care Med (2007) 2.87
The Eldicus prospective, observational study of triage decision making in European intensive care units. Part II: intensive care benefit for the elderly. Crit Care Med (2012) 2.46
The relation of near-infrared spectroscopy with changes in peripheral circulation in critically ill patients. Crit Care Med (2011) 2.37
Blood lactate monitoring in critically ill patients: a systematic health technology assessment. Crit Care Med (2009) 2.21
Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial. Intensive Care Med (2003) 2.05
The prognostic value of blood lactate levels relative to that of vital signs in the pre-hospital setting: a pilot study. Crit Care (2008) 1.85
Persistent peripheral and microcirculatory perfusion alterations after out-of-hospital cardiac arrest are associated with poor survival. Crit Care Med (2012) 1.78
International study on microcirculatory shock occurrence in acutely ill patients. Crit Care Med (2015) 1.64
Microvascular perfusion as a target for fluid resuscitation in experimental circulatory shock. Crit Care Med (2014) 1.63
The Eldicus prospective, observational study of triage decision making in European intensive care units: part I--European Intensive Care Admission Triage Scores. Crit Care Med (2012) 1.59
CD14 receptor occupancy in severe sepsis: results of a phase I clinical trial with a recombinant chimeric CD14 monoclonal antibody (IC14). Crit Care Med (2004) 1.58
Noninvasive monitoring of peripheral perfusion. Intensive Care Med (2005) 1.54
Organ donations and unused potential donations in traumatic brain injury, subarachnoid haemorrhage and intracerebral haemorrhage. Intensive Care Med (2006) 1.53
Re-thinking resuscitation: leaving blood pressure cosmetics behind and moving forward to permissive hypotension and a tissue perfusion-based approach. Crit Care (2013) 1.50
The use of opioids and sedatives and time until death after withdrawing mechanical ventilation and vasoactive drugs in a dutch intensive care unit. Anesth Analg (2011) 1.48
External validation of a prognostic model predicting time of death after withdrawal of life support in neurocritical patients. Crit Care Med (2012) 1.43
Direct cost analysis of intensive care unit stay in four European countries: applying a standardized costing methodology. Value Health (2012) 1.42
Use of a peripheral perfusion index derived from the pulse oximetry signal as a noninvasive indicator of perfusion. Crit Care Med (2002) 1.41
The effect of goal-directed therapy on mortality in patients with sepsis - earlier is better: a meta-analysis of randomized controlled trials. Crit Care (2014) 1.35
Prevalence and incidence of severe sepsis in Dutch intensive care units. Crit Care (2004) 1.33
Biomarkers for the prediction of acute kidney injury: a narrative review on current status and future challenges. Clin Kidney J (2012) 1.27
The prognostic value of the subjective assessment of peripheral perfusion in critically ill patients. Crit Care Med (2009) 1.24
Remifentanil-propofol analgo-sedation shortens duration of ventilation and length of ICU stay compared to a conventional regimen: a centre randomised, cross-over, open-label study in the Netherlands. Intensive Care Med (2008) 1.16
Imminent brain death: point of departure for potential heart-beating organ donor recognition. Intensive Care Med (2010) 1.16
The impact of severe sepsis on health-related quality of life: a long-term follow-up study. Anesth Analg (2008) 1.15
Implications of ICU triage decisions on patient mortality: a cost-effectiveness analysis. Crit Care (2011) 1.14
Colistin, SDD and resistance: nihil novi sub sole. Intensive Care Med (2014) 1.13
Year in review in Intensive Care Medicine 2014: III. Severe infections, septic shock, healthcare-associated infections, highly resistant bacteria, invasive fungal infections, severe viral infections, Ebola virus disease and paediatrics. Intensive Care Med (2015) 1.12
Deferred proxy consent in emergency critical care research: ethically valid and practically feasible. Crit Care Med (2009) 1.11
Prognostic value of blood lactate levels: does the clinical diagnosis at admission matter? J Trauma (2009) 1.11
Clinical review: Clinical imaging of the sublingual microcirculation in the critically ill--where do we stand? Crit Care (2012) 1.11
Quality of life on admission to the intensive care: can we query the relatives? Intensive Care Med (2003) 1.10
Neutrophil gelatinase-associated lipocalin clearance during veno-venous continuous renal replacement therapy in critically ill patients. Intensive Care Med (2010) 1.10
Don't take vitals, take a lactate. Intensive Care Med (2007) 1.09
The brain is not dead when the cortex is dead. Crit Care Med (2015) 1.08
Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients. Crit Care (2009) 1.08
Assessment of tissue oxygen saturation during a vascular occlusion test using near-infrared spectroscopy: the role of probe spacing and measurement site studied in healthy volunteers. Crit Care (2009) 1.07
Quality of life before intensive care unit admission is a predictor of survival. Crit Care (2007) 1.05
Electrical impedance tomography measured at two thoracic levels can visualize the ventilation distribution changes at the bedside during a decremental positive end-expiratory lung pressure trial. Crit Care (2011) 1.04
Experiences of critically ill patients in the ICU. Intensive Crit Care Nurs (2008) 1.03
Lung volume calculated from electrical impedance tomography in ICU patients at different PEEP levels. Intensive Care Med (2009) 1.02
Clinical review: Circulatory shock--an update: a tribute to Professor Max Harry Weil. Crit Care (2012) 0.97
The heterogeneity of the microcirculation in critical illness. Clin Chest Med (2008) 0.97
Understanding venous return. Intensive Care Med (2014) 0.96
Inability to obtain deferred consent due to early death in emergency research: effect on validity of clinical trial results. Intensive Care Med (2010) 0.95
A microcosting study of intensive care unit stay in the Netherlands. J Intensive Care Med (2008) 0.94
Fluid resuscitation in ICU patients: quo vadis? Intensive Care Med (2015) 0.92
A computer program for interpreting pulmonary artery catheterization data: results of the European HEMODYN Resident Study. Intensive Care Med (2003) 0.90
Development of a clinical data warehouse from an intensive care clinical information system. Comput Methods Programs Biomed (2010) 0.90
Peripheral vasoconstriction influences thenar oxygen saturation as measured by near-infrared spectroscopy. Intensive Care Med (2012) 0.90
Clinical monitoring of peripheral perfusion: there is more to learn. Crit Care (2014) 0.90
Urinary Neutrophil Gelatinase-Associated Lipocalin Measured on Admission to the Intensive Care Unit Accurately Discriminates between Sustained and Transient Acute Kidney Injury in Adult Critically Ill Patients. Nephron Extra (2011) 0.90
Cost-consequence analysis of remifentanil-based analgo-sedation vs. conventional analgesia and sedation for patients on mechanical ventilation in the Netherlands. Crit Care (2010) 0.89
Inflatable external leg compression prevents orthostatic hypotension in a patient with a traumatic cervical spinal cord injury. Future Cardiol (2013) 0.88
Single-nucleotide polymorphisms in the Toll-like receptor pathway increase susceptibility to infections in severely injured trauma patients. J Trauma Acute Care Surg (2013) 0.88
Early peripheral perfusion-guided fluid therapy in patients with septic shock. Am J Respir Crit Care Med (2015) 0.87
A european, multicenter, observational study to assess the value of gastric-to-end tidal PCO2 difference in predicting postoperative complications. Anesth Analg (2004) 0.87
Laser speckle imaging identification of increases in cortical microcirculatory blood flow induced by motor activity during awake craniotomy. J Neurosurg (2012) 0.86
Is organ donation from brain dead donors reaching an inescapable and desirable nadir? Transplantation (2011) 0.85
Withdrawal of life-sustaining treatment in a mixed intensive care unit: most common in patients with catastropic brain injury. Neurocrit Care (2012) 0.84
Measurement of end-expiratory lung volume in intubated children without interruption of mechanical ventilation. Intensive Care Med (2009) 0.84
Conceptual issues specifically related to health-related quality of life in critically ill patients. Crit Care (2009) 0.83
Peripheral perfusion index as an early predictor for central hypovolemia in awake healthy volunteers. Anesth Analg (2013) 0.82
Clinical assessment of peripheral perfusion to predict postoperative complications after major abdominal surgery early: a prospective observational study in adults. Crit Care (2014) 0.82
Remarkable changes in the choice of timing to discuss organ donation with the relatives of a patient: a study in 228 organ donations in 20 years. Crit Care (2011) 0.82
Near-infrared spectroscopy for monitoring peripheral tissue perfusion in critically ill patients. Rev Bras Ter Intensiva (2011) 0.81
Optimizing intensive care capacity using individual length-of-stay prediction models. Crit Care (2007) 0.81
Health-related quality of life in critically ill patients: how to score and what is the clinical impact? Curr Opin Crit Care (2009) 0.81
Donor conversion rates depend on the assessment tools used in the evaluation of potential organ donors. Intensive Care Med (2011) 0.81
Right ventricular unloading after initiation of venovenous extracorporeal membrane oxygenation. Am J Respir Crit Care Med (2015) 0.81
Year in review in Intensive Care Medicine 2013: II. Sedation, invasive and noninvasive ventilation, airways, ARDS, ECMO, family satisfaction, end-of-life care, organ donation, informed consent, safety, hematological issues in critically ill patients. Intensive Care Med (2014) 0.81
Nitroglycerin reverts clinical manifestations of poor peripheral perfusion in patients with circulatory shock. Crit Care (2014) 0.80
Imminent brain death and brain death are not the same: reply to Verheijde and Rady. Intensive Care Med (2010) 0.79
Noninvasive functional liver blood flow measurement: comparison between bolus dose and steady-state clearance of sorbitol in a small-rodent model. Am J Physiol Gastrointest Liver Physiol (2009) 0.79
A novel approach to assess hemorrhagic shock severity using the arterially determined left ventricular isovolumic contraction period. Am J Physiol Heart Circ Physiol (2013) 0.79
Improvement of care for ICU patients with delirium by early screening and treatment: study protocol of iDECePTIvE study. Implement Sci (2014) 0.79
Study Design of the Microcirculatory Shock Occurrence in Acutely Ill Patients (microSOAP): an International Multicenter Observational Study of Sublingual Microcirculatory Alterations in Intensive Care Patients. Crit Care Res Pract (2012) 0.78
Clinical assessment of peripheral circulation. Curr Opin Crit Care (2015) 0.77
Selective digestive tract decontamination decreases time on ventilator in Guillain-Barré syndrome. Neurocrit Care (2011) 0.77
Year in review in Intensive Care Medicine 2013: I. Acute kidney injury, ultrasound, hemodynamics, cardiac arrest, transfusion, neurocritical care, and nutrition. Intensive Care Med (2013) 0.77
[Peripheral circulation in critically ill patients: non-invasive methods for the assessment of the peripheral perfusion]. Ned Tijdschr Geneeskd (2013) 0.77
Legal implications of clinical practice guidelines. Intensive Care Med (2002) 0.77
Postoperative sublingual microcirculatory derangement following esophagectomy is prevented with dobutamine. Clin Hemorheol Microcirc (2011) 0.77
Accidental methanol ingestion: case report. BMC Emerg Med (2010) 0.76
Lactate and microcirculation as suitable targets for hemodynamic optimization in resuscitation of circulatory shock. Curr Opin Crit Care (2017) 0.76
Fewer intensive care unit refusals and a higher capacity utilization by using a cyclic surgical case schedule. J Crit Care (2007) 0.75
Functional status after intensive care. J Rehabil Med (2009) 0.75
Comment on "Attitudes of European physicians, nurses, patients, and families regarding end-of-life decisions: the ETHICATT study" by Sprung et al. Intensive Care Med (2007) 0.75
Bis maltolato oxovanadium (BMOV) and ischemia/reperfusion-induced acute kidney injury in rats. Intensive Care Med Exp (2014) 0.75
The crystal ball in end-of-life care. Crit Care Med (2008) 0.75
Predicting mortality: how fast can you go? Crit Care Med (2005) 0.75
A national multicenter trial on family presence during brain death determination: the FABRA study. Neurocrit Care (2012) 0.75