Published in Clin Ther on April 01, 2008
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A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo. Cell Metab (2006) 2.82
Sparse coding and high-order correlations in fine-scale cortical networks. Nature (2010) 2.00
NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage. Ann Neurol (2014) 1.95
A chemical-genetic approach to study G protein regulation of beta cell function in vivo. Proc Natl Acad Sci U S A (2009) 1.90
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Sex hormone ratio changes in men and postmenopausal women with coronary artery disease. Menopause (2007) 1.56
Conformational changes involved in G-protein-coupled-receptor activation. Trends Pharmacol Sci (2008) 1.29
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Simultaneous determination of berberine and palmatine in rat plasma by HPLC-ESI-MS after oral administration of traditional Chinese medicinal preparation Huang-Lian-Jie-Du decoction and the pharmacokinetic application of the method. J Pharm Biomed Anal (2005) 1.07
Early inhibition of HIF-1alpha with small interfering RNA reduces ischemic-reperfused brain injury in rats. Neurobiol Dis (2008) 1.05
Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: a comparison with ACE inhibition. Mol Med (2010) 1.05
Characterization of human coronavirus etiology in Chinese adults with acute upper respiratory tract infection by real-time RT-PCR assays. PLoS One (2012) 1.04
High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice. Am J Respir Cell Mol Biol (2012) 1.04
Phosphorylation of Vpr regulates HIV type 1 nuclear import and macrophage infection. AIDS Res Hum Retroviruses (2002) 1.00
Cerebralcare Granule, a Chinese herb compound preparation, improves cerebral microcirculatory disorder and hippocampal CA1 neuron injury in gerbils after ischemia-reperfusion. J Ethnopharmacol (2010) 0.98
Beneficial metabolic effects caused by persistent activation of beta-cell M3 muscarinic acetylcholine receptors in transgenic mice. Endocrinology (2010) 0.95
Sugar and auxin signaling pathways respond to high-temperature stress during anther development as revealed by transcript profiling analysis in cotton. Plant Physiol (2014) 0.94
Increased IL-17-producing CD4(+) T cells in patients with esophageal cancer. Cell Immunol (2011) 0.94
Metabolic roles of the M3 muscarinic acetylcholine receptor studied with M3 receptor mutant mice: a review. J Recept Signal Transduct Res (2008) 0.94
Ymf 1029A-E, preussomerin analogues from the fresh-water-derived fungus YMF 1.01029. J Nat Prod (2008) 0.94
Comparison of the metabolism of baicalin in rats orally administered with Radix scutellariae extract and Shuang-Huang-Lian extract. Chem Pharm Bull (Tokyo) (2005) 0.92
Suppression of human ovarian SKOV-3 cancer cell growth by Duchesnea phenolic fraction is associated with cell cycle arrest and apoptosis. Gynecol Oncol (2007) 0.91
Hyperbaric oxygen preconditioning attenuates hyperglycemia-enhanced hemorrhagic transformation by inhibiting matrix metalloproteinases in focal cerebral ischemia in rats. Exp Neurol (2013) 0.91
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Transmembrane protein 166 regulates autophagic and apoptotic activities following focal cerebral ischemic injury in rats. Exp Neurol (2011) 0.90
Use of an in situ disulfide cross-linking strategy to study the dynamic properties of the cytoplasmic end of transmembrane domain VI of the M3 muscarinic acetylcholine receptor. Biochemistry (2006) 0.90
Long-term persistence of robust antibody and cytotoxic T cell responses in recovered patients infected with SARS coronavirus. PLoS One (2006) 0.89
A new algorithm to predict warfarin dose from polymorphisms of CYP4F2 , CYP2C9 and VKORC1 and clinical variables: derivation in Han Chinese patients with non valvular atrial fibrillation. Thromb Haemost (2012) 0.88
CMTM3 inhibits cell migration and invasion and correlates with favorable prognosis in gastric cancer. Cancer Sci (2013) 0.87
TLR4 as receptor for HMGB1 induced muscle dysfunction in myositis. Ann Rheum Dis (2012) 0.87
Antibody-antigen-adjuvant conjugates enable co-delivery of antigen and adjuvant to dendritic cells in cis but only have partial targeting specificity. PLoS One (2012) 0.87
Structural evidence of perfluorooctane sulfonate transport by human serum albumin. Chem Res Toxicol (2012) 0.86
Determination of azelnidipine by LC-ESI-MS and its application to a pharmacokinetic study in healthy Chinese volunteers. Pharmazie (2008) 0.86
Measurement of fexofenadine concentration in micro-sample human plasma by a rapid and sensitive LC-MS/MS employing protein precipitation: application to a clinical pharmacokinetic study. Biomed Chromatogr (2010) 0.86
Determination of huperzine A in human plasma by liquid chromatography-electrospray tandem mass spectrometry: application to a bioequivalence study on Chinese volunteers. Biomed Chromatogr (2008) 0.86
Chemokine/chemokine receptor interactions contribute to the accumulation of Th17 cells in patients with esophageal squamous cell carcinoma. Hum Immunol (2012) 0.85
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Identification of pigment epithelium-derived factor as an adipocyte-derived inflammatory factor. Mol Med (2012) 0.85
Three-dimensional localization of neurons in cortical tetrode recordings. J Neurophysiol (2011) 0.85
Ran GTPase protein promotes human pancreatic cancer proliferation by deregulating the expression of Survivin and cell cycle proteins. Biochem Biophys Res Commun (2013) 0.85
Duchesnea phenolic fraction inhibits in vitro and in vivo growth of cervical cancer through induction of apoptosis and cell cycle arrest. Exp Biol Med (Maywood) (2008) 0.84
Stable isotope metabolic labeling-based quantitative phosphoproteomic analysis of Arabidopsis mutants reveals ethylene-regulated time-dependent phosphoproteins and putative substrates of constitutive triple response 1 kinase. Mol Cell Proteomics (2013) 0.84
A long-term observation of olfactory ensheathing cells transplantation to repair white matter and functional recovery in a focal ischemia model in rat. Brain Res (2010) 0.83
Prior antiplatelet agent use and outcomes after intravenous thrombolysis with recombinant tissue plasminogen activator in acute ischemic stroke: a meta-analysis of cohort studies and randomized controlled trials. Int J Stroke (2014) 0.82
Protamine sulfate-nanodiamond hybrid nanoparticles as a vector for MiR-203 restoration in esophageal carcinoma cells. Nanoscale (2013) 0.82
Adsorption performance of VOCs in ordered mesoporous silicas with different pore structures and surface chemistry. J Hazard Mater (2010) 0.82
AhR-mediated effects of dioxin on neuronal acetylcholinesterase expression in vitro. Environ Health Perspect (2013) 0.82
STAT3 blockade with shRNA enhances radiosensitivity in Hep-2 human laryngeal squamous carcinoma cells. Oncol Rep (2010) 0.81
GmFLD, a soybean homolog of the autonomous pathway gene FLOWERING LOCUS D, promotes flowering in Arabidopsis thaliana. BMC Plant Biol (2014) 0.81
[Clinical pathology feature and prognostic factors of cervical lymph node metastases in hypopharyngeal carcinoma]. Zhonghua Er Bi Yan Hou Ke Za Zhi (2004) 0.81
Effects of SLCO1B1 polymorphisms on the pharmacokinetics and pharmacodynamics of repaglinide in healthy Chinese volunteers. Eur J Clin Pharmacol (2011) 0.81
An alternative high output tissue microarray technique. Diagn Pathol (2013) 0.81
Rapid and sensitive analysis of multiple bioactive constituents in tripterygium glycosides tablets using liquid chromatography coupled with time-of-flight mass spectrometry. J Sep Sci (2015) 0.81
Study of the pharmacokinetics and intragastric pH of rabeprazole given as successive intravenous infusion to healthy Chinese volunteers. Eur J Clin Pharmacol (2010) 0.81
Biological and clinical significance of p75NTR expression in laryngeal squamous epithelia and laryngocarcinoma. Acta Otolaryngol (2011) 0.80
Determination of adefovir by LC-ESI-MS-MS and its application to a pharmacokinetic study in healthy Chinese volunteers. J Chromatogr Sci (2009) 0.80
Chronic hydrocephalus after experimental subarachnoid hemorrhage. PLoS One (2013) 0.80
Analysis of cell membrane permeabilization mechanics and pore shape due to ultrashort electrical pulsing. Med Biol Eng Comput (2010) 0.80
[Evaluation of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of hilar and mediastinal masses of unknown etiologies]. Zhonghua Yi Xue Za Zhi (2012) 0.80
The protective effect of Cerebralcare Granule® on brain edema, cerebral microcirculatory disturbance, and neuron injury in a focal cerebral ischemia rat model. Microcirculation (2012) 0.80
[Development of desulfated chondroitin sulfate C as a novel chiral selector in capillary electrophoresis and enantioseparation of cilnidipine]. Se Pu (2004) 0.79
A novel drug-phospholipid complex enriched with micelles: preparation and evaluation in vitro and in vivo. Int J Nanomedicine (2013) 0.79
Attenuation of atherosclerotic lesions in diabetic apolipoprotein E-deficient mice using gene silencing of macrophage migration inhibitory factor. J Cell Mol Med (2015) 0.79
Gamma-secretase inhibitor (GSI1) attenuates morphological cerebral vasospasm in 24h after experimental subarachnoid hemorrhage in rats. Neurosci Lett (2009) 0.79
Mammalian target of rapamycin (mTOR) inhibition reduces cerebral vasospasm following a subarachnoid hemorrhage injury in canines. Exp Neurol (2011) 0.79
Self-assembled highly ordered ethane-bridged periodic mesoporous organosilica and its application in HPLC. J Sep Sci (2011) 0.78
An intron SNP rs807185 in ATG4A decreases the risk of lung cancer in a southwest Chinese population. Eur J Cancer Prev (2016) 0.78
Controversy and progress for treatment of acute cholangitis after Tokyo Guidelines (TG13). Biosci Trends (2016) 0.78
Molecularly imprinted layer-coated silica nanoparticles for selective solid-phase extraction of bisphenol A from chemical cleansing and cosmetics samples. Anal Chim Acta (2009) 0.78
[Detection of KRAS gene mutation and its clinical significance in colorectal adenocarcinoma]. Zhonghua Bing Li Xue Za Zhi (2012) 0.78
Enhanced distribution and extended elimination of glycyrrhetinic acid in mice liver by mPEG-PLA modified (mPEGylated) liposome. J Pharm Biomed Anal (2009) 0.78
Quantitative analysis of 23-hydroxybetulinic acid in mouse plasma using electrospray liquid chromatography/mass spectrometry. Rapid Commun Mass Spectrom (2005) 0.78
Rapid loss of both CD4+ and CD8+ T lymphocyte subsets during the acute phase of severe acute respiratory syndrome. Chin Med J (Engl) (2003) 0.78
Transport of gatifloxacin involves Na+/Ca2+ exchange and excludes P-glycoprotein and multidrug resistance associated-proteins in primary cultured rat brain endothelial cells. Eur J Pharmacol (2009) 0.78
Differential effects of gonadotropin-releasing hormone (GnRH)-I and GnRH-II on prostate cancer cell signaling and death. J Clin Endocrinol Metab (2005) 0.78
Combination of raloxifene, aspirin and estrogen as novel paradigm of hormone replacement therapy in rabbit model of menopause. Acta Pharmacol Sin (2011) 0.78
Homogalacturonans from preinfused green tea: structural characterization and anticomplementary activity of their sulfated derivatives. J Agric Food Chem (2013) 0.78
Status of and prospects for cancer vaccines against hepatocellular carcinoma in clinical trials. Biosci Trends (2015) 0.78
p53-induced uncoupling expression of aquaporin-4 and inwardly rectifying K+ 4.1 channels in cytotoxic edema after subarachnoid hemorrhage. CNS Neurosci Ther (2012) 0.78
Reward inference by primate prefrontal and striatal neurons. J Neurosci (2014) 0.78
Sequencing and bioinformatics analysis of the metal-related genes in Acidithiobacillus ferrooxidans strain DC. Folia Microbiol (Praha) (2013) 0.77
[Tenofovir rescue therapy for chronic hepatitis B patients after suboptimal response to treatment with lamivudine plus adefovir dipivoxil]. Zhonghua Nei Ke Za Zhi (2014) 0.77
Pifithrin-alpha reduces cerebral vasospasm by attenuating apoptosis of endothelial cells in a subarachnoid haemorrhage model of rat. Chin Med J (Engl) (2008) 0.77
Arsenite suppression of BMP signaling in human keratinocytes. Toxicol Appl Pharmacol (2013) 0.77
Diagnostic application of PIK3CA mutation analysis in Chinese esophageal cancer patients. Diagn Pathol (2014) 0.77
Ala/Thr(201) in extracellular loop 2 and Leu/Phe(290) in transmembrane domain 6 of type 1 frog gonadotropin-releasing hormone receptor confer differential ligand sensitivity and signal transduction. Endocrinology (2003) 0.77
Cancer stem cells may be mostly maintained by fluctuating hypoxia. Med Hypotheses (2010) 0.77
Longitudinal profiles of immunoglobulin G antibodies against severe acute respiratory syndrome coronavirus components and neutralizing activities in recovered patients. Scand J Infect Dis (2011) 0.77
In-vivo and in-vitro studies on the effect of Huang-Lian-Jie-Du-Tang on nimodipine transport across rat blood-brain barrier. J Pharm Pharmacol (2007) 0.77
Pharmacokinetics of betamethasone and betamethasone 17-monopropionate in Chinese healthy volunteers after intramuscular injection of betamethasone phosphate/betamethasone dipropionate. Arzneimittelforschung (2011) 0.77