Published in Curr Opin Hematol on July 01, 2008
Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development. Cell Stem Cell (2009) 1.85
Stem cell therapy with overexpressed VEGF and PDGF genes improves cardiac function in a rat infarct model. PLoS One (2009) 1.11
Hyaluronic acid and thrombin upregulate MT1-MMP through PI3K and Rac-1 signaling and prime the homing-related responses of cord blood hematopoietic stem/progenitor cells. Stem Cells Dev (2010) 1.02
Impact of hematopoietic chimerism at day +14 on engraftment after unrelated donor umbilical cord blood transplantation for hematologic malignancies. Haematologica (2009) 0.94
Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells. PLoS One (2011) 0.88
Defective pulmonary innate immune responses post-stem cell transplantation; review and results from one model system. Front Immunol (2013) 0.83
Effect of anti-CD52 antibody alemtuzumab on ex-vivo culture of umbilical cord blood stem cells. J Hematol Oncol (2008) 0.80
Usefulness of umbilical cord blood cells in era of hematopoiesis research. Int J Stem Cells (2009) 0.77
Immunophenotypic comparison of heterogenous non-sorted versus sorted mononuclear cells from human umbilical cord blood: a novel cell enrichment approach. Cytotechnology (2013) 0.76
Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis. Lancet Oncol (2010) 4.67
Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients. Biol Blood Marrow Transplant (2005) 2.82
Effect of donor-recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis. Lancet Oncol (2011) 2.49
Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell (2005) 2.26
Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. Cancer Res (2010) 1.92
Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis. Blood (2005) 1.82
Double unit grafts successfully extend the application of umbilical cord blood transplantation in adults with acute leukemia. Blood (2012) 1.81
microRNA 184 regulates expression of NFAT1 in umbilical cord blood CD4+ T cells. Blood (2009) 1.75
Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT. Blood (2012) 1.63
Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement. Blood (2009) 1.58
Reduced-intensity conditioning transplantation in acute leukemia: the effect of source of unrelated donor stem cells on outcomes. Blood (2012) 1.55
Stat5 expression is critical for mast cell development and survival. Blood (2003) 1.48
Hematopoietic recovery after unrelated umbilical cord-blood allogeneic transplantation in adults treated with in vivo stem cell factor (R-MetHuSCF) and filgrastim administration. Leuk Res (2003) 1.39
Who is the better donor for older hematopoietic transplant recipients: an older-aged sibling or a young, matched unrelated volunteer? Blood (2013) 1.27
Strategies to enhance umbilical cord blood stem cell engraftment in adult patients. Expert Rev Hematol (2010) 1.25
Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells. Blood (2002) 1.25
A novel role of complement in mobilization: immunodeficient mice are poor granulocyte-colony stimulating factor mobilizers because they lack complement-activating immunoglobulins. Stem Cells (2007) 1.23
Cited2 is required for normal hematopoiesis in the murine fetal liver. Blood (2007) 1.21
Hematopoietic reconstitution with androgenetic and gynogenetic stem cells. Genes Dev (2007) 1.19
STAT5 requires the N-domain to maintain hematopoietic stem cell repopulating function and appropriate lymphoid-myeloid lineage output. Exp Hematol (2007) 1.19
Stat5 is essential for early B cell development but not for B cell maturation and function. J Immunol (2007) 1.17
STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease. Blood (2009) 1.17
Expansion of LTC-ICs and maintenance of p21 and BCL-2 expression in cord blood CD34(+)/CD38(-) early progenitors cultured over human MSCs as a feeder layer. Stem Cells (2002) 1.14
A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells. Blood (2010) 1.14
Effects of a leukemia-associated gain-of-function mutation of SHP-2 phosphatase on interleukin-3 signaling. J Biol Chem (2005) 1.11
HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency. Blood (2012) 1.10
The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90. Nat Immunol (2012) 1.08
Optimization of isolation and further characterization of umbilical-cord-blood-derived very small embryonic/ epiblast-like stem cells (VSELs). Eur J Haematol (2009) 1.07
STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells. Blood (2008) 1.06
Hematopoietic-repopulating defects from STAT5-deficient bone marrow are not fully accounted for by loss of thrombopoietin responsiveness. Blood (2003) 1.05
Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood (2010) 1.04
Reduced expression of NFAT-associated genes in UCB versus adult CD4+ T lymphocytes during primary stimulation. Blood (2003) 1.04
Abnormal hematopoiesis in Gab2 mutant mice. Blood (2007) 1.04
Kinetics of myeloid and lymphocyte recovery and infectious complications after unrelated umbilical cord blood versus HLA-matched unrelated donor allogeneic transplantation in adults. Br J Haematol (2004) 1.03
A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma. Blood (2002) 1.03
Influence of human leucocyte antigen disparity and graft lymphocytes on allogeneic engraftment and survival after umbilical cord blood transplant in adults. Br J Haematol (2007) 1.03
Umbilical cord blood transplantation: a new alternative option. Hematology Am Soc Hematol Educ Program (2005) 1.01
Elevated AF1q expression is a poor prognostic marker for adult acute myeloid leukemia patients with normal cytogenetics. Am J Hematol (2009) 0.98
Spontaneous autologous graft-versus-host disease in plasma cell myeloma autograft recipients: flow cytometric analysis of hematopoietic progenitor cell grafts. Biol Blood Marrow Transplant (2011) 0.97
MIR29B regulates expression of MLLT11 (AF1Q), an MLL fusion partner, and low MIR29B expression associates with adverse cytogenetics and poor overall survival in AML. Br J Haematol (2011) 0.97
Stat5 expression is required for IgE-mediated mast cell function. J Immunol (2006) 0.96
A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival. Oncogene (2004) 0.96
Early failure of frontline rituximab-containing chemo-immunotherapy in diffuse large B cell lymphoma does not predict futility of autologous hematopoietic cell transplantation. Biol Blood Marrow Transplant (2014) 0.95
Direct comparison of umbilical cord blood versus bone marrow-derived endothelial precursor cells in mediating neovascularization in response to vascular ischemia. Biol Blood Marrow Transplant (2006) 0.94
The effect of the composition of unrelated donor bone marrow and peripheral blood progenitor cell grafts on transplantation outcomes. Biol Blood Marrow Transplant (2009) 0.92
Identification of 6-benzylthioinosine as a myeloid leukemia differentiation-inducing compound. Cancer Res (2008) 0.91
Safety and efficacy of bone marrow-derived autologous CD133+ stem cell therapy. Front Biosci (Elite Ed) (2011) 0.90
Extending cord blood transplant to adults: dealing with problems and results overall. Semin Hematol (2010) 0.90
Cutting edge: IL-5 primes Th2 cytokine-producing capacity in eosinophils through a STAT5-dependent mechanism. J Immunol (2004) 0.88
Donor characteristics affecting graft failure, graft-versus-host disease, and survival after unrelated donor transplantation with reduced-intensity conditioning for hematologic malignancies. Biol Blood Marrow Transplant (2011) 0.87
A STAT5 modifier locus on murine chromosome 7 modulates engraftment of hematopoietic stem cells during steady-state hematopoiesis. Blood (2004) 0.87
Complex systems biology approach to understanding coordination of JAK-STAT signaling. Biosystems (2007) 0.87
Th17 related cytokines in acute myeloid leukemia. Front Biosci (Landmark Ed) (2012) 0.87
Hematopoietic stem cell transplant into non-myeloablated W/Wv mice to detect steady-state engraftment defects. Methods Mol Biol (2008) 0.86
The safety of autologous intracoronary stem cell injections in a porcine model of chronic myocardial ischemia. J Invasive Cardiol (2006) 0.85
Complement fragment 3a priming of umbilical cord blood progenitors: safety profile. Biol Blood Marrow Transplant (2013) 0.84
Serine phosphorylation of the Stat5a C-terminus is a driving force for transformation. Front Biosci (Landmark Ed) (2011) 0.84
Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3. J Biol Chem (2011) 0.84
Pretransplantation consolidation chemotherapy decreases leukemia relapse after autologous blood and bone marrow transplants for acute myelogenous leukemia in first remission. Biol Blood Marrow Transplant (2006) 0.84
Bone marrow transplantation combined with gene therapy to induce antigen-specific tolerance and ameliorate EAE. Mol Ther (2005) 0.84
Recipient-specific tolerance after HLA-mismatched umbilical cord blood stem cell transplantation. Transplantation (2005) 0.84
Molecular targets for the treatment of juvenile myelomonocytic leukemia. Adv Hematol (2011) 0.83
Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production. J Biol Chem (2011) 0.83
Umbilical cord blood transplantation for acute myeloid leukemia. Curr Opin Hematol (2009) 0.83
Reduced CTLA-4 protein and messenger RNA expression in umbilical cord blood T lymphocytes. Exp Hematol (2002) 0.82
Grb2-associated binding (Gab) proteins in hematopoietic and immune cell biology. Am J Blood Res (2011) 0.82
Comparison of survival times in a transplant study of hematologic disorders. Contemp Clin Trials (2005) 0.82
Genotype-dependent effects of TGF-β1 on mast cell function: targeting the Stat5 pathway. J Immunol (2013) 0.82
Bcl2 overexpression rescues the hematopoietic stem cell defects in Ku70-deficient mice by restoration of quiescence. Blood (2014) 0.82
Phase I evaluation of prolonged-infusion gemcitabine with mitoxantrone for relapsed or refractory acute leukemia. J Clin Oncol (2002) 0.81
Mutation of STAT1/3 binding sites in gp130(FXXQ) knock-in mice does not alter hematopoietic stem cell repopulation or self-renewal potential. Am J Stem Cells (2012) 0.81
Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors. Curr Gene Ther (2004) 0.80
Retroviral transduction of murine hematopoietic stem cells. Methods Mol Biol (2008) 0.80
Umbilical cord blood-selected CD133(+) cells exhibit vasculogenic functionality in vitro and in vivo. Cytotherapy (2010) 0.80
Cytoplasmic localization of phosphorylated STAT5 in human acute myeloid leukemia is inversely correlated with Flt3-ITD. Blood (2007) 0.80
Peritransplant use of ultraviolet-B irradiation (UV-B) therapy is detrimental to allogeneic stem cell transplantation outcome. Biol Blood Marrow Transplant (2006) 0.79
An ENU-induced recessive mutation in Mpl leads to thrombocytopenia with overdominance. Exp Hematol (2008) 0.79
Gab adapter proteins as therapeutic targets for hematologic disease. Adv Hematol (2011) 0.78
Deficient IFN-gamma expression in umbilical cord blood (UCB) T cells can be rescued by IFN-gamma-mediated increase in NFATc2 expression. J Clin Immunol (2003) 0.78
High-dose carmustine, etoposide, and cisplatin for autologous stem cell transplantation with or without involved-field radiation for relapsed/refractory lymphoma: an effective regimen with low morbidity and mortality. Biol Blood Marrow Transplant (2005) 0.78
Tissue inhibitor of matrix metalloproteinase-1 overexpression in M1 myeloblasts impairs IL-6-induced differentiation. Oncogene (2004) 0.77
Umbilical cord blood stem cells: implications for cardiovascular regenerative medicine. J Mol Cell Cardiol (2007) 0.77
Randomised comparison of two B-cell purging protocols for patients with B-cell non-Hodgkin lymphoma: in vivo purging with rituximab versus ex vivo purging with CliniMACS CD34 cell enrichment device. Br J Haematol (2006) 0.77
Hematopoiesis in mice is extremely resilient to wide variation in TIMP/MMP balance. Blood Cells Mol Dis (2008) 0.77
Gab2 promotes hematopoietic stem cell maintenance and self-renewal synergistically with STAT5. PLoS One (2010) 0.77
Nanoproteomic assays on hematopoietic stem cells. Methods Mol Biol (2014) 0.77
Umbilical cord blood stem cells for myocardial repair and regeneration. Methods Mol Biol (2010) 0.76
The expanding tool kit for hematopoietic stem cell research. Methods Mol Biol (2008) 0.75