The pilocarpine model of temporal lobe epilepsy.

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Published in J Neurosci Methods on April 26, 2008

Authors

Giulia Curia1, Daniela Longo, Giuseppe Biagini, Roland S G Jones, Massimo Avoli

Author Affiliations

1: Montreal Neurological Institute and Departments of Neurology & Neurosurgery and Physiology, McGill University, Montreal, QC, Canada.

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Carbachol induces fast oscillations in the medial but not in the lateral entorhinal cortex of the isolated guinea pig brain. J Neurophysiol (1999) 0.85

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Electrophysiologic abnormalities of the hippocampus in the pilocarpine/cycloheximide model of chronic spontaneous seizures. Epilepsia (2002) 0.84

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Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period. Epilepsia (2009) 0.89

Epileptiform synchronization in the cingulate cortex. Epilepsia (2008) 0.88

Ripple activity in the dentate gyrus of dishinibited hippocampus-entorhinal cortex slices. J Neurosci Res (2005) 0.87

Epileptiform synchronization in the rat insular and perirhinal cortices in vitro. Eur J Neurosci (2007) 0.87

Depression of glutamate and GABA release by presynaptic GABAB receptors in the entorhinal cortex in normal and chronically epileptic rats. Neurosignals (2007) 0.87

Reversibility of the endothelial dysfunction after CPAP therapy in OSAS patients. Int J Cardiol (2011) 0.86

Nicotine and neurodegeneration in ageing. Toxicol Lett (2002) 0.85

Independent epileptiform discharge patterns in the olfactory and limbic areas of the in vitro isolated Guinea pig brain during 4-aminopyridine treatment. J Neurophysiol (2010) 0.85

Neurokinin-receptor-mediated depolarization of cortical neurons elicits an increase in glutamate release at excitatory synapses. Eur J Neurosci (2002) 0.85

Hypoxia markers are expressed in interneurons exposed to recurrent seizures. Neuromolecular Med (2012) 0.84

Valproate modifies spontaneous excitation and inhibition at cortical synapses in vitro. Neuropharmacology (2003) 0.84

Acute cerebellitis in varicella: a ten year case series and systematic review of the literature. Ital J Pediatr (2014) 0.84

The H current blocker ZD7288 decreases epileptiform hyperexcitability in the rat neocortex by depressing synaptic transmission. Neuropharmacology (2006) 0.83

Pierre Gloor (1923-2003): an appreciation. Epilepsia (2004) 0.82

Lacosamide: a new approach to target voltage-gated sodium currents in epileptic disorders. CNS Drugs (2009) 0.82

Visual recognition and visually guided action after early bilateral lesion of occipital cortex: a behavioral study of a 4.6-year-old girl. Neurocase (2006) 0.82

Lamina-specific differences in GABA(B) autoreceptor-mediated regulation of spontaneous GABA release in rat entorhinal cortex. Neuropharmacology (2004) 0.82

Perirhinal cortex hyperexcitability in pilocarpine-treated epileptic rats. Hippocampus (2010) 0.82

Resilience to audiogenic seizures is associated with p-ERK1/2 dephosphorylation in the subiculum of Fmr1 knockout mice. Front Cell Neurosci (2013) 0.81

Homocysteine potentiates seizures and cell loss induced by pilocarpine treatment. Neuromolecular Med (2009) 0.81

Thalamocortical oscillations in a genetic model of absence seizures. Eur J Neurosci (2002) 0.81

Seizure-like discharges induced by 4-aminopyridine in the olfactory system of the in vitro isolated guinea pig brain. Epilepsia (2013) 0.81

Allergy and psychologic evaluations of patients with multiple drug intolerance syndrome. Intern Emerg Med (2011) 0.81

The role of NMDA receptor subtypes in short-term plasticity in the rat entorhinal cortex. Neural Plast (2008) 0.81

Perirhinal cortex and temporal lobe epilepsy. Front Cell Neurosci (2013) 0.80

Treating epilepsy via adaptive neurostimulation: a reinforcement learning approach. Int J Neural Syst (2009) 0.80

Protective but not anticonvulsant effects of ghrelin and JMV-1843 in the pilocarpine model of Status epilepticus. PLoS One (2013) 0.80

Mutations in MFSD8/CLN7 are a frequent cause of variant-late infantile neuronal ceroid lipofuscinosis. Hum Mutat (2009) 0.80

Evidence-based modeling of network discharge dynamics during periodic pacing to control epileptiform activity. J Neurosci Methods (2011) 0.79

Epileptiform synchronization and GABA(B) receptor antagonism in the juvenile rat hippocampus. J Pharmacol Exp Ther (2002) 0.79

Ethosuximide modifies network excitability in the rat entorhinal cortex via an increase in GABA release. Neuropharmacology (2011) 0.79

Neocortical potassium currents are enhanced by the antiepileptic drug lamotrigine. Epilepsia (2002) 0.79

Methodological approaches to exploring epileptic disorders in the human brain in vitro. J Neurosci Methods (2006) 0.79

Encephalocraniocutaneous lipomatosis (ECCL): neuroradiological findings in three patients and a new association with fibrous dysplasia. Am J Med Genet A (2011) 0.78

NMDA receptor-mediated transmission contributes to network 'hyperexcitability' in the rat insular cortex. Eur J Neurosci (2006) 0.78

Diminished presynaptic GABA(B) receptor function in the neocortex of a genetic model of absence epilepsy. Neurosignals (2009) 0.78

The epileptic hippocampus revisited: back to the future. Epilepsy Curr (2007) 0.77

Is there such a thing as "generalized" epilepsy? Adv Exp Med Biol (2014) 0.77

MR differential diagnosis of acute deep grey matter pathology in paediatric patients. Pediatr Radiol (2012) 0.77

Volume-conducted epileptiform events between adjacent necortical slices in an interface tissue chamber. J Neurosci Methods (2005) 0.77

Neocortical hyperexcitability in a genetic model of absence seizures and its reduction by levetiracetam. Epilepsia (2006) 0.77

Cell type-specific properties of subicular GABAergic currents shape hippocampal output firing mode. PLoS One (2012) 0.77

"Jasper's Basic Mechanisms of the Epilepsies" Workshop. Epilepsia (2010) 0.77

Activity-dependent changes in excitability of perirhinal cortex networks in vitro. Pflugers Arch (2014) 0.77