Published in FEMS Microbiol Lett on June 28, 2008
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Identification of the first prokaryotic collagen sequence motif that mediates binding to human collagen receptors, integrins alpha2beta1 and alpha11beta1. J Biol Chem (2008) 1.22
Comparative genomics suggests an independent origin of cytoplasmic incompatibility in Cardinium hertigii. PLoS Genet (2012) 1.19
A variable region within the genome of Streptococcus pneumoniae contributes to strain-strain variation in virulence. PLoS One (2011) 1.08
Expanding the family of collagen proteins: recombinant bacterial collagens of varying composition form triple-helices of similar stability. Biomacromolecules (2010) 1.00
Prediction of molecular mimicry candidates in human pathogenic bacteria. Virulence (2013) 0.96
New adhesin functions of surface-exposed pneumococcal proteins. BMC Microbiol (2010) 0.95
Role of Pht proteins in attachment of Streptococcus pneumoniae to respiratory epithelial cells. Infect Immun (2014) 0.95
Sortase anchored proteins of Streptococcus uberis play major roles in the pathogenesis of bovine mastitis in dairy cattle. Vet Res (2010) 0.87
The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group A Streptococcus shows significant similarity to immunomodulatory HIV protein gp41. J Biol Chem (2013) 0.84
Role for streptococcal collagen-like protein 1 in M1T1 group A Streptococcus resistance to neutrophil extracellular traps. Infect Immun (2014) 0.82
Activation of the classical complement pathway by Bacillus anthracis is the primary mechanism for spore phagocytosis and involves the spore surface protein BclA. J Immunol (2012) 0.82
Activator role of the pneumococcal Mga-like virulence transcriptional regulator. J Bacteriol (2012) 0.81
Lineage structure of Streptococcus pneumoniae may be driven by immune selection on the groEL heat-shock protein. Sci Rep (2017) 0.78
Diverse evolutionary patterns of pneumococcal antigens identified by pangenome-wide immunological screening. Proc Natl Acad Sci U S A (2017) 0.76
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Collagen-like proteins of pathogenic streptococci. Mol Microbiol (2017) 0.75
Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis. PLoS Biol (2017) 0.75
Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species. Genome Biol (2010) 2.60
Role of conjugative elements in the evolution of the multidrug-resistant pandemic clone Streptococcus pneumoniaeSpain23F ST81. J Bacteriol (2008) 2.51
Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis. J Clin Invest (2002) 2.50
Competence-programmed predation of noncompetent cells in the human pathogen Streptococcus pneumoniae: genetic requirements. Proc Natl Acad Sci U S A (2005) 2.24
Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization. Infect Immun (2003) 1.83
Role of inflammatory mediators in resistance and susceptibility to pneumococcal infection. Infect Immun (2002) 1.59
Upper and lower respiratory tract infection by Streptococcus pneumoniae is affected by pneumolysin deficiency and differences in capsule type. Infect Immun (2002) 1.50
The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion. J Exp Med (2009) 1.48
Role of HtrA in the virulence and competence of Streptococcus pneumoniae. Infect Immun (2004) 1.40
The role of Streptococcus pneumoniae sortase A in colonisation and pathogenesis. Microbes Infect (2005) 1.37
Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia. Am J Respir Crit Care Med (2008) 1.33
Nitric oxide levels regulate macrophage commitment to apoptosis or necrosis during pneumococcal infection. FASEB J (2004) 1.33
Detection of large numbers of pneumococcal virulence genes in streptococci of the mitis group. J Clin Microbiol (2010) 1.32
Construction and immunological characterization of a novel nontoxic protective pneumolysin mutant for use in future pneumococcal vaccines. Infect Immun (2006) 1.32
Low CD4 T cell immunity to pneumolysin is associated with nasopharyngeal carriage of pneumococci in children. J Infect Dis (2007) 1.31
Pneumococcal behavior and host responses during bronchopneumonia are affected differently by the cytolytic and complement-activating activities of pneumolysin. Infect Immun (2003) 1.30
Streptococcus pneumoniae-associated human macrophage apoptosis after bacterial internalization via complement and Fcgamma receptors correlates with intracellular bacterial load. J Infect Dis (2003) 1.28
Declining serotype coverage of new pneumococcal conjugate vaccines relating to the carriage of Streptococcus pneumoniae in young children. Vaccine (2011) 1.28
Genomic diversity between strains of the same serotype and multilocus sequence type among pneumococcal clinical isolates. Infect Immun (2006) 1.27
Control of virulence by the two-component system CiaR/H is mediated via HtrA, a major virulence factor of Streptococcus pneumoniae. J Bacteriol (2004) 1.23
Contribution of a response regulator to the virulence of Streptococcus pneumoniae is strain dependent. Infect Immun (2003) 1.23
Transcriptional regulation, occurrence and putative role of the Pht family of Streptococcus pneumoniae. Microbiology (2010) 1.19
Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin. J Clin Microbiol (2006) 1.18
Dominant role of nucleotide substitution in the diversification of serotype 3 pneumococci over decades and during a single infection. PLoS Genet (2013) 1.17
Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaks. J Infect Dis (2007) 1.16
Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds. J Biol Chem (2011) 1.15
Innate immune defense against pneumococcal pneumonia requires pulmonary complement component C3. Infect Immun (2005) 1.14
Identification of a detrimental role for NK cells in pneumococcal pneumonia and sepsis in immunocompromised hosts. Microbes Infect (2005) 1.14
Regulation of gene expression in Streptococcus pneumoniae by response regulator 09 is strain dependent. J Bacteriol (2006) 1.10
Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol (2005) 1.08
Pneumolysin causes neuronal cell death through mitochondrial damage. Infect Immun (2007) 1.07
Contribution of the ATP-dependent protease ClpCP to the autolysis and virulence of Streptococcus pneumoniae. Infect Immun (2005) 1.06
Isolation and characterization of a new plasmid pSpnP1 from a multidrug-resistant clone of Streptococcus pneumoniae. Plasmid (2007) 1.05
What is different about serotype 1 pneumococci? Future Microbiol (2012) 1.04
Comparative genomic analysis of ten Streptococcus pneumoniae temperate bacteriophages. J Bacteriol (2009) 1.04
Natural antibodies against several pneumococcal virulence proteins in children during the pre-pneumococcal-vaccine era: the generation R study. Infect Immun (2011) 1.03
The contribution of PspC to pneumococcal virulence varies between strains and is accomplished by both complement evasion and complement-independent mechanisms. Infect Immun (2006) 1.03
Innate immunity and the pneumococcus. Microbiology (2006) 1.01
Effects of cigarette smoke condensate on pneumococcal biofilm formation and pneumolysin. Eur Respir J (2012) 1.01
Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine. PLoS One (2013) 0.99
Development of a prophage typing system and analysis of prophage carriage in Streptococcus pneumoniae. Appl Environ Microbiol (2009) 0.98
Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization. Cell Microbiol (2010) 0.98
Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases. J Infect Dis (2008) 0.96
Novel mucosal vaccines generated by genetic conjugation of heterologous proteins to pneumolysin (PLY) from Streptococcus pneumoniae. Vaccine (2010) 0.96
Crystal structure of the C-terminal region of Streptococcus mutans antigen I/II and characterization of salivary agglutinin adherence domains. J Biol Chem (2011) 0.96
Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium. Infect Immun (2004) 0.94
Increase in serotype 6C pneumococcal carriage, United Kingdom. Emerg Infect Dis (2010) 0.94
Identification of a secreted cholesterol-dependent cytolysin (mitilysin) from Streptococcus mitis. J Bacteriol (2006) 0.93
Nitric oxide exerts distinct effects in local and systemic infections with Streptococcus pneumoniae. Microb Pathog (2004) 0.92
Immunisation with anthrolysin O or a genetic toxoid protects against challenge with the toxin but not against Bacillus anthracis. Vaccine (2007) 0.88
Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types. J Med Microbiol (2011) 0.87
The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study. Clin Vaccine Immunol (2010) 0.86
The mechanism of pneumolysin-induced cochlear hair cell death in the rat. J Physiol (2005) 0.83
An operon in Streptococcus pneumoniae containing a putative alkylhydroperoxidase D homologue contributes to virulence and the response to oxidative stress. Microb Pathog (2006) 0.83
Expression and regulation of the Escherichia coli O157:H7 effector proteins NleH1 and NleH2. PLoS One (2012) 0.81
Differential alveolar epithelial injury and protein expression in pneumococcal pneumonia. Exp Lung Res (2012) 0.81
Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function. Eur J Immunol (2014) 0.80
Streptococcus pneumoniae induces exocytosis of Weibel-Palade bodies in pulmonary endothelial cells. Cell Microbiol (2011) 0.78
Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets. J Clin Invest (2015) 0.77
Diphtheria-like disease caused by toxigenic Corynebacterium ulcerans strain. Emerg Infect Dis (2014) 0.76
Expression, purification, crystallization and preliminary X-ray crystallographic data from TktA, a transketolase from the lactic acid bacterium Lactobacillus salivarius. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.76
Pneumococci causing invasive disease in children prior to the introduction of pneumococcal conjugate vaccine in Scotland. J Med Microbiol (2006) 0.75
Vaccine preventable meningitis in Malaysia: epidemiology and management. Expert Rev Anti Infect Ther (2015) 0.75