| Rank | Title | Journal | Year | PubWeight™‹?› |
|---|---|---|---|---|
| 1 | Optimization of purine based PDE1/PDE5 inhibitors to a potent and selective PDE5 inhibitor for the treatment of male ED. | Bioorg Med Chem Lett | 2005 | 0.81 |
| 2 | Design, synthesis, and evaluation of fused heterocyclic analogs of SCH 58261 as adenosine A2A receptor antagonists. | Bioorg Med Chem Lett | 2008 | 0.76 |
| 3 | Design and synthesis of xanthine analogues as potent and selective PDE5 inhibitors. | Bioorg Med Chem Lett | 2002 | 0.75 |
| 4 | Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M(2) muscarinic receptor antagonists via benzamide modification. | Bioorg Med Chem Lett | 2002 | 0.75 |