Published in Circulation on June 16, 2008
Oxidized LDL: diversity, patterns of recognition, and pathophysiology. Antioxid Redox Signal (2010) 1.47
NOX and inflammation in the vascular adventitia. Free Radic Biol Med (2009) 1.37
Oxidative risk for atherothrombotic cardiovascular disease. Free Radic Biol Med (2009) 1.24
Intermittent hypoxia has organ-specific effects on oxidative stress. Am J Physiol Regul Integr Comp Physiol (2008) 1.19
Current Concepts of the Role of Oxidized LDL Receptors in Atherosclerosis. Curr Atheroscler Rep (2012) 1.16
Evaluating oxidative stress in human cardiovascular disease: methodological aspects and considerations. Curr Med Chem (2012) 1.15
The discovery of LOX-1, its ligands and clinical significance. Cardiovasc Drugs Ther (2011) 1.12
LOX-1 in atherosclerosis: biological functions and pharmacological modifiers. Cell Mol Life Sci (2012) 1.04
CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits. Aging (Albany NY) (2010) 1.04
Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy. Carcinogenesis (2009) 1.00
The Dynamics of Oxidized LDL during Atherogenesis. J Lipids (2011) 0.98
Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular disease. Int J Hypertens (2010) 0.95
Overexpression of scavenger receptor LOX-1 in endothelial cells promotes atherogenesis in the ApoE(-/-) mouse model. Cardiovasc Pathol (2010) 0.92
Lysophosphatidic acid effects on atherosclerosis and thrombosis. Clin Lipidol (2011) 0.91
Periodontal treatment decreases plasma oxidized LDL level and oxidative stress. Clin Oral Investig (2010) 0.88
Scavenger receptor structure and function in health and disease. Cells (2015) 0.88
Antioxidant effects of statins in patients with atherosclerotic cerebrovascular disease. J Clin Neurol (2014) 0.87
The LOX-1 Scavenger Receptor and Its Implications in the Treatment of Vascular Disease. Cardiol Res Pract (2012) 0.87
OxLDL-targeted iron oxide nanoparticles for in vivo MRI detection of perivascular carotid collar induced atherosclerotic lesions in ApoE-deficient mice. J Lipid Res (2012) 0.86
Overexpression of CCN3 inhibits inflammation and progression of atherosclerosis in apolipoprotein E-deficient mice. PLoS One (2014) 0.84
Temporal dissociation between myeloperoxidase (MPO)-modified LDL and MPO elevations during chronic sleep restriction and recovery in healthy young men. PLoS One (2011) 0.84
An eicosanoid-centric view of atherothrombotic risk factors. Cell Mol Life Sci (2012) 0.84
Unveiling LOX-1 receptor interplay with nanotopography: mechanotransduction and atherosclerosis onset. Sci Rep (2013) 0.83
Paradoxical effect of a pequi oil-rich diet on the development of atherosclerosis: balance between antioxidant and hyperlipidemic properties. Braz J Med Biol Res (2012) 0.80
Using oxidized low-density lipoprotein autoantibodies to predict restenosis after balloon angioplasty in patients with acute myocardial infarction. PLoS One (2013) 0.79
Tenascin-C produced by oxidized LDL-stimulated macrophages increases foam cell formation through Toll-like receptor-4. Mol Cells (2012) 0.79
LDL-lipids from patients with hypercholesterolaemia and Alzheimer's disease are inflammatory to microvascular endothelial cells: mitigation by statin intervention. Clin Sci (Lond) (2015) 0.78
Age-associated downregulation of vasohibin-1 in vascular endothelial cells. Aging Cell (2016) 0.78
The role of Siglec-1 and SR-BI interaction in the phagocytosis of oxidized low density lipoprotein by macrophages. PLoS One (2013) 0.78
Oxidized LDL and Fructosamine Associated with Severity of Coronary Artery Atherosclerosis in Insulin Resistant Pigs Fed a High Fat/High NaCl Diet. PLoS One (2015) 0.78
Cannabidiol-2',6'-dimethyl ether as an effective protector of 15-lipoxygenase-mediated low-density lipoprotein oxidation in vitro. Biol Pharm Bull (2011) 0.77
LOX-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men. Atherosclerosis (2013) 0.77
High-Density Lipoprotein Prevents Endoplasmic Reticulum Stress-Induced Downregulation of Liver LOX-1 Expression. PLoS One (2015) 0.77
Gr-1⁺CD11b⁺ immature myeloid cells (IMC) promote resistance of pro-inflammatory T cells to suppression by regulatory T cells in atherosclerotic Apo E- deficient mice. PLoS One (2014) 0.77
Involvement of oxidative stress in atherosclerosis development in subjects with sarcopenic obesity. Obes Sci Pract (2017) 0.77
LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies. Int J Mol Sci (2017) 0.75
ABCA1 mRNA expression and cholesterol outflow in U937 cells. Int J Clin Exp Pathol (2015) 0.75
High intrinsic aerobic capacity and pomegranate juice are protective against macrophage atherogenecity: studies in high- vs. low-capacity runner (HCR vs. LCR) rats. J Nutr Biochem (2015) 0.75
MicroRNA-98 rescues proliferation and alleviates ox-LDL-induced apoptosis in HUVECs by targeting LOX-1. Exp Ther Med (2017) 0.75
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet (2008) 9.39
The first identification and retrospective study of Severe Fever with Thrombocytopenia Syndrome in Japan. J Infect Dis (2013) 4.92
Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet. Circ Res (2007) 2.87
Regulation of pancreatic beta cell mass by neuronal signals from the liver. Science (2008) 2.74
Atypical proteinase K-resistant prion protein (PrPres) observed in an apparently healthy 23-month-old Holstein steer. Jpn J Infect Dis (2003) 2.64
Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. Immunity (2002) 2.47
WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells. J Biol Chem (2005) 2.25
Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells. J Clin Invest (2010) 2.22
Lysophosphatidic acid is a bioactive mediator in ovarian cancer. Biochim Biophys Acta (2002) 2.18
Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance. Cell Metab (2009) 2.13
The alpha/beta interferon response controls tissue tropism and pathogenicity of poliovirus. J Virol (2005) 2.13
Positional cloning and characterization reveal the molecular basis for soybean maturity locus E1 that regulates photoperiodic flowering. Proc Natl Acad Sci U S A (2012) 2.11
Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion. Hum Mol Genet (2004) 2.10
Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care (2006) 2.06
Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity. Science (2006) 2.02
Signals from intra-abdominal fat modulate insulin and leptin sensitivity through different mechanisms: neuronal involvement in food-intake regulation. Cell Metab (2006) 1.93
Mechanisms of renal structural alterations in combined hypercholesterolemia and renal artery stenosis. Arterioscler Thromb Vasc Biol (2003) 1.91
Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan. J Clin Endocrinol Metab (2008) 1.91
Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement. Diabetes (2003) 1.86
Mediation of electronegative low-density lipoprotein signaling by LOX-1: a possible mechanism of endothelial apoptosis. Circ Res (2009) 1.83
Adiposity and cardiovascular disorders: disturbance of the regulatory system consisting of humoral and neuronal signals. Circ Res (2007) 1.80
Two coordinately regulated homologs of FLOWERING LOCUS T are involved in the control of photoperiodic flowering in soybean. Plant Physiol (2010) 1.80
Pyramidal and extrapyramidal involvement in experimental infection of cynomolgus monkeys with enterovirus 71. J Med Virol (2002) 1.78
WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells. Hum Mol Genet (2006) 1.76
Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway. Arterioscler Thromb Vasc Biol (2012) 1.75
Blockade of the nuclear factor-κB pathway in the endothelium prevents insulin resistance and prolongs life spans. Circulation (2012) 1.75
LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis. Pharmacol Ther (2002) 1.74
Intracellular and extracellular ATP coordinately regulate the inverse correlation between osteoclast survival and bone resorption. J Biol Chem (2012) 1.66
Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways. Am J Physiol Cell Physiol (2007) 1.65
LOX index, a novel predictive biochemical marker for coronary heart disease and stroke. Clin Chem (2010) 1.65
ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress. Cell Metab (2008) 1.62
Importance of endothelial NF-κB signalling in vascular remodelling and aortic aneurysm formation. Cardiovasc Res (2012) 1.61
Modulation of angiotensin II-mediated hypertension and cardiac remodeling by lectin-like oxidized low-density lipoprotein receptor-1 deletion. Hypertension (2008) 1.58
A novel gene silencer, pyrrole-imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function. J Hypertens (2009) 1.58
The human prefrontal and parietal association cortices are involved in NO-GO performances: an event-related fMRI study. Neuroimage (2002) 1.51
LOX-1 mediates vascular lipid retention under hypertensive state. J Hypertens (2010) 1.49
Optimal cutoff point of waist circumference and use of home blood pressure as a definition of metabolic syndrome: the Ohasama study. Am J Hypertens (2008) 1.49
Detection of Merkel cell polyomavirus in Merkel cell carcinoma and Kaposi's sarcoma. J Med Virol (2009) 1.46
Lectin-like oxidized LDL receptor 1 is involved in CRP-mediated complement activation. Clin Chem (2011) 1.46
Serum soluble CD27 level is associated with outcome in patients with diffuse large B-cell lymphoma treated with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone. Leuk Lymphoma (2012) 1.45
Differential localization of neurons susceptible to enterovirus 71 and poliovirus type 1 in the central nervous system of cynomolgus monkeys after intravenous inoculation. J Gen Virol (2004) 1.43
Protection against influenza virus infection in polymeric Ig receptor knockout mice immunized intranasally with adjuvant-combined vaccines. J Immunol (2002) 1.42
Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42. J Biol Chem (2003) 1.42
Large-scale analysis of full-length cDNAs from the tomato (Solanum lycopersicum) cultivar Micro-Tom, a reference system for the Solanaceae genomics. BMC Genomics (2010) 1.41
A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis. J Biol Chem (2005) 1.40