Published in Pharm Res on June 26, 2008
Formulation strategies for drug delivery of tacrolimus: An overview. Int J Pharm Investig (2012) 0.86
Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol Pathol (2003) 3.99
Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. Biomed Pharmacother (2004) 2.71
Proliferative and nonproliferative lesions of the rat and mouse hepatobiliary system. Toxicol Pathol (2010) 2.09
Inhaled environmental combustion particles cause myocardial injury in the Wistar Kyoto rat. Toxicol Sci (2003) 1.66
Targeting of nanoparticles to the clathrin-mediated endocytic pathway. Biochem Biophys Res Commun (2006) 1.64
Discovery of metabolomics biomarkers for early detection of nephrotoxicity. Toxicol Pathol (2009) 1.64
Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells. Biomacromolecules (2008) 1.59
A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy. J Biol Chem (2010) 1.41
Area under the curve as a dose metric for promotional responses following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. Toxicol Appl Pharmacol (2003) 1.41
Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis. Am J Pathol (2002) 1.39
Extraskeletal osteosarcoma with cystic appearance in an aged Sprague-Dawley rat. Toxicol Pathol (2005) 1.30
Dose-additive carcinogenicity of a defined mixture of "dioxin-like compounds". Environ Health Perspect (2005) 1.29
Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination. Environ Mol Mutagen (2007) 1.10
Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. Cancer Res (2006) 1.08
Vascular and cardiac impairments in rats inhaling ozone and diesel exhaust particles. Environ Health Perspect (2010) 1.07
Differential attenuation of oxidative/nitrosative injuries in early prostatic neoplastic lesions in TRAMP mice by dietary antioxidants. Prostate (2006) 1.05
A grading scheme for the assessment of proliferative lesions of the mouse prostate in the TRAMP model. Toxicol Pathol (2003) 1.04
Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis. Am J Pathol (2005) 1.03
Spontaneous lesions in control B6C3F1 mice and recommended sectioning of male accessory sex organs. Toxicol Pathol (2002) 1.03
Enhanced oral absorption of paclitaxel in a novel self-microemulsifying drug delivery system with or without concomitant use of P-glycoprotein inhibitors. Pharm Res (2004) 1.02
Increase in cardiovascular pathology in female Sprague-Dawley rats following chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3,3',4,4',5-pentachlorobiphenyl. Cardiovasc Toxicol (2003) 1.01
The potential of lipid emulsion for ocular delivery of lipophilic drugs. Eur J Pharm Biopharm (2004) 1.01
Terbutaline is a developmental neurotoxicant: effects on neuroproteins and morphology in cerebellum, hippocampus, and somatosensory cortex. J Pharmacol Exp Ther (2003) 1.01
Hepatic enzyme induction: histopathology. Toxicol Pathol (2010) 0.99
Reduced sulfur mustard-induced skin toxicity in cyclooxygenase-2 knockout and celecoxib-treated mice. Toxicol Appl Pharmacol (2004) 0.98
Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity. Am J Physiol Heart Circ Physiol (2009) 0.98
Successfully improving ocular drug delivery using the cationic nanoemulsion, novasorb. J Drug Deliv (2012) 0.98
Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta. Endocrinology (2004) 0.97
Mitochondrial damage revealed by morphometric and semiquantitative analysis of mouse pup cardiomyocytes following in utero and postnatal exposure to zidovudine and lamivudine. Toxicol Sci (2004) 0.96
The role of particulate matter-associated zinc in cardiac injury in rats. Environ Health Perspect (2008) 0.96
One-month diesel exhaust inhalation produces hypertensive gene expression pattern in healthy rats. Environ Health Perspect (2008) 0.95
Histological biocompatibility of a stainless steel miniature glaucoma drainage device in humans: a case report. Toxicol Pathol (2009) 0.94
cAMP-dependent oncogenic action of Rap1b in the thyroid gland. J Biol Chem (2004) 0.94
A critical comparison of murine pathology and epidemiological data of TCDD, PCB126, and PeCDF. Toxicol Pathol (2007) 0.94
Nanoparticle-cell interactions: drug delivery implications. Crit Rev Ther Drug Carrier Syst (2008) 0.94
Dimethylarsinic acid: results of chronic toxicity/oncogenicity studies in F344 rats and in B6C3F1 mice. Toxicology (2006) 0.94
Toxicity and carcinogenicity of riddelliine in rats and mice. Toxicol Lett (2003) 0.93
Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program. Toxicol Pathol (2005) 0.93
Oral delivery system prolongs blood circulation of docetaxel nanocapsules via lymphatic absorption. Proc Natl Acad Sci U S A (2013) 0.93
Comparative long-term preclinical safety evaluation of two glatiramoid compounds (glatiramer Acetate, Copaxone(R), and TV-5010, protiramer) in rats and monkeys. Toxicol Pathol (2011) 0.92
An investigation of the effects of late-onset dietary restriction on prostate cancer development in the TRAMP mouse. Toxicol Pathol (2005) 0.91
Excipient effects on in vitro cytotoxicity of a novel paclitaxel self-emulsifying drug delivery system. J Pharm Sci (2003) 0.91
Reprogrammed and transmissible intestinal microbiota confer diminished susceptibility to induced colitis in TMF-/- mice. Proc Natl Acad Sci U S A (2014) 0.91
Synergistic effect of influenza a virus on endotoxin-induced mortality in rat pups: a potential model for sudden infant death syndrome. Pediatr Res (2002) 0.90
Ephedrine plus caffeine causes age-dependent cardiovascular responses in Fischer 344 rats. Am J Physiol Heart Circ Physiol (2005) 0.90
Safety and proof-of-concept efficacy of inhaled drug loaded nano- and immunonanoparticles in a c-Raf transgenic lung cancer model. Curr Cancer Drug Targets (2013) 0.90
Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of tacrolimus, a P-gp substrate drug. J Control Release (2008) 0.90
Classification of proliferative hepatocellular lesions in harlan sprague-dawley rats chronically exposed to dioxin-like compounds. Toxicol Pathol (2005) 0.90
In vitro adsorption of plasma proteins onto the surface (charges) modified-submicron emulsions for intravenous administration. Eur J Pharm Biopharm (2005) 0.90
Antibody conjugated PLGA nanoparticles for targeted delivery of paclitaxel palmitate: efficacy and biofate in a lung cancer mouse model. Small (2013) 0.90
Surface characterization and biocompatibility of restorative resin containing nanoparticles. Biomacromolecules (2008) 0.89
Cardiovascular and blood coagulative effects of pulmonary zinc exposure. Toxicol Appl Pharmacol (2005) 0.89
Poly(sebacic acid-co-ricinoleic acid) biodegradable carrier for paclitaxel: in vitro release and in vivo toxicity. J Biomed Mater Res A (2004) 0.89
Subchronic inhalation of zinc sulfate induces cardiac changes in healthy rats. Toxicol Appl Pharmacol (2008) 0.89
Loss of TMF/ARA160 protein renders colonic mucus refractory to bacterial colonization and diminishes intestinal susceptibility to acute colitis. J Biol Chem (2012) 0.87
Fourteen-week toxicity study of green tea extract in rats and mice. Toxicol Pathol (2010) 0.86
Respiratory tract lesions in noninhalation studies. Toxicol Pathol (2007) 0.86
Proceedings of the 2010 National Toxicology Program Satellite Symposium. Toxicol Pathol (2010) 0.86
Drug-induced thrombosis--experimental, clinical, and mechanistic considerations. Toxicol Pathol (2007) 0.86
Effect of diet and animal care/housing protocols on body weight, survival, tumor incidences, and nephropathy severity of F344 rats in chronic studies. Toxicol Pathol (2003) 0.86
Gingival carcinogenicity in female Harlan Sprague-Dawley rats following two-year oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds. Toxicol Sci (2004) 0.86
Gentamicin extended release from an injectable polymeric implant. J Control Release (2006) 0.86
Histopathology and apoptosis in an animal model of reversible renal injury. Exp Toxicol Pathol (2010) 0.85
Extensive surface studies help to analyse zeta potential data: the case of cationic emulsions. Chem Phys Lipids (2004) 0.85
Toxicity and carcinogenicity of the water disinfection byproduct, dibromoacetic acid, in rats and mice. Toxicology (2006) 0.85
Cationic submicron emulsions for pulmonary DNA immunization. J Control Release (2004) 0.85
The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats. Toxicol Pathol (2003) 0.85
Safety and biodistribution profile of placental-derived mesenchymal stromal cells (PLX-PAD) following intramuscular delivery. Toxicol Pathol (2009) 0.84
Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice. Arch Toxicol (2005) 0.84
Ocular antisense oligonucleotide delivery by cationic nanoemulsion for improved treatment of ocular neovascularization: an in-vivo study in rats and mice. J Control Release (2011) 0.84
Biomarkers of Oxidative Stress Study IV: ozone exposure of rats and its effect on antioxidants in plasma and bronchoalveolar lavage fluid. Free Radic Biol Med (2011) 0.84
Early effects of iodine on DNA synthesis in sulfur mustard-induced skin lesions. Arch Toxicol (2006) 0.84
Intratumoral delivery of paclitaxel for treatment of orthotopic prostate cancer. J Pharm Sci (2009) 0.84
Occult cardiotoxicity--toxic effects on cardiac ischemic tolerance. Toxicol Pathol (2009) 0.84
Characterization of liver toxicity in F344/N rats and B6C3F1 mice after exposure to a flame retardant containing lower molecular weight polybrominated diphenyl ethers. Exp Toxicol Pathol (2008) 0.84
A safety and tolerability study of differently-charged nanoparticles for local pulmonary drug delivery. Toxicol Appl Pharmacol (2010) 0.83
Mechanisms of exocrine pancreatic toxicity induced by oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley Rats. Toxicol Sci (2005) 0.83
Gastrointestinal hyperplasia with altered expression of DNA polymerase beta. PLoS One (2009) 0.83
Characterization of bronchiolar metaplasia of the alveolar epithelium in female Sprague-Dawley rats exposed to 3,3',4,4',5-pentachlorobiphenyl (PCB126). Toxicol Pathol (2004) 0.83
Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract. Exp Toxicol Pathol (2006) 0.83
Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine. Arch Toxicol (2005) 0.83
Systemic imbalance of essential metals and cardiac gene expression in rats following acute pulmonary zinc exposure. J Toxicol Environ Health A (2006) 0.83
Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants. Exp Dermatol (2012) 0.83
Hepatocellular carcinomas in B6C3F1 mice treated with Ginkgo biloba extract for two years differ from spontaneous liver tumors in cancer gene mutations and genomic pathways. Toxicol Pathol (2012) 0.82
Reproductive lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin and dioxin-like compounds. Toxicol Pathol (2009) 0.82
Proceedings of the 2011 National Toxicology Program Satellite Symposium. Toxicol Pathol (2011) 0.82
Bio-imaging of colorectal cancer models using near infrared labeled epidermal growth factor. PLoS One (2012) 0.82
Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice. DNA Repair (Amst) (2003) 0.82
Protective effect of topical iodine containing anti-inflammatory drugs against sulfur mustard-induced skin lesions. Arch Toxicol (2003) 0.82
Biocompatibility and safety evaluation of a ricinoleic acid-based poly(ester-anhydride) copolymer after implantation in rats. J Biomed Mater Res A (2010) 0.82
High plasma levels and effective lymphatic uptake of docetaxel in an orally available nanotransporter formulation. Cancer Res (2011) 0.82
Dietary salt exacerbates isoproterenol-induced cardiomyopathy in rats. Toxicol Pathol (2011) 0.81
Particulate matter inhalation exacerbates cardiopulmonary injury in a rat model of isoproterenol-induced cardiomyopathy. Inhal Toxicol (2010) 0.81
The ligand nanoparticle conjugation approach for targeted cancer therapy. Curr Drug Metab (2012) 0.81
Induction of interleukin-1beta, tumour necrosis factor-alpha and apoptosis in mouse organs by amphotericin B is neutralized by conjugation with arabinogalactan. J Antimicrob Chemother (2005) 0.81
Comparison of chronic toxicity and carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in 2-year bioassays in female Sprague-Dawley rats. Mol Nutr Food Res (2006) 0.81
Treatment of osteomyelitis in rats by injection of degradable polymer releasing gentamicin. J Control Release (2008) 0.81
Adrenergic differentiation and Ret expression in rat pheochromocytomas. Endocr Pathol (2008) 0.81