Published in Am J Physiol Heart Circ Physiol on June 27, 2008
Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype. J Biol Chem (2008) 2.81
Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression. FEBS J (2009) 1.49
Signaling mechanisms that regulate smooth muscle cell differentiation. Arterioscler Thromb Vasc Biol (2011) 1.34
The four-and-a-half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone. J Biol Chem (2009) 1.01
Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells. Hum Mol Genet (2009) 0.97
Modulation of myocardin function by the ubiquitin E3 ligase UBR5. J Biol Chem (2010) 0.93
Transcriptional control of cardiac fibroblast plasticity. J Mol Cell Cardiol (2015) 0.84
The LIM-only protein FHL2 reduces vascular lesion formation involving inhibition of proliferation and migration of smooth muscle cells. PLoS One (2014) 0.80
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LIM-only protein FHL2 is a positive regulator of liver X receptors in smooth muscle cells involved in lipid homeostasis. Mol Cell Biol (2014) 0.77
Noncoding RNAs in smooth muscle cell homeostasis: implications in phenotypic switch and vascular disorders. Pflugers Arch (2016) 0.77
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The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A (2003) 3.40
Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors. Dev Cell (2003) 2.28
FHL2, a novel tissue-specific coactivator of the androgen receptor. EMBO J (2000) 2.25
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF. Mol Cell (2004) 2.19
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The multifunctional roles of the four-and-a-half-LIM only protein FHL2. Cell Mol Life Sci (2006) 1.99
Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells. J Biol Chem (2004) 1.98
Cross-binding of factors to functionally different promoter elements in c-fos and skeletal actin genes. Mol Cell Biol (1989) 1.94
Requirement of a myocardin-related transcription factor for development of mammary myoepithelial cells. Mol Cell Biol (2006) 1.89
Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation. Circulation (2001) 1.74
Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation. Proc Natl Acad Sci U S A (2005) 1.72
The transcriptional coactivator FHL2 transmits Rho signals from the cell membrane into the nucleus. EMBO J (2002) 1.72
Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proc Natl Acad Sci U S A (2005) 1.70
Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors. J Biol Chem (2004) 1.64
A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM. Mol Cell Biol (2000) 1.61
Expression patterns of FHL/SLIM family members suggest important functional roles in skeletal muscle and cardiovascular system. Mech Dev (2000) 1.61
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FHL2 (SLIM3) is not essential for cardiac development and function. Mol Cell Biol (2000) 1.34
MKL1 mediates TGF-beta1-induced alpha-smooth muscle actin expression in human renal epithelial cells. Am J Physiol Renal Physiol (2008) 1.21
The developmentally regulated expression of serum response factor plays a key role in the control of smooth muscle-specific genes. Dev Biol (1998) 1.19
Deficiency in the LIM-only protein Fhl2 impairs skin wound healing. J Cell Biol (2007) 1.13
An endogenous inhibitor of focal adhesion kinase blocks Rac1/JNK but not Ras/ERK-dependent signaling in vascular smooth muscle cells. J Biol Chem (2003) 1.11
LIM mineralization protein-1 potentiates bone morphogenetic protein responsiveness via a novel interaction with Smurf1 resulting in decreased ubiquitination of Smads. J Biol Chem (2006) 1.11
Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction. Proc Natl Acad Sci U S A (2007) 1.10
LIM-only protein, CRP2, switched on smooth muscle gene activity in adult cardiac myocytes. Proc Natl Acad Sci U S A (2006) 1.06
Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions. Development (2003) 0.98
The ternary complex factor Net regulates cell migration through inhibition of PAI-1 expression. Mol Cell Biol (2005) 0.98
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Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors. J Biol Chem (2004) 1.64
Diaphanous 1 and 2 regulate smooth muscle cell differentiation by activating the myocardin-related transcription factors. Arterioscler Thromb Vasc Biol (2006) 1.63
Focal adhesion kinase is essential for cardiac looping and multichamber heart formation. Genesis (2010) 1.51
Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors. Am J Physiol Heart Circ Physiol (2006) 1.46
The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression. Circ Res (2007) 1.38
Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding. J Clin Invest (2017) 1.38
Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy. Circ Res (2006) 1.34
Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment. Mol Cell Biol (2007) 1.18
An endogenous inhibitor of focal adhesion kinase blocks Rac1/JNK but not Ras/ERK-dependent signaling in vascular smooth muscle cells. J Biol Chem (2003) 1.11
FAK regulates cardiomyocyte survival following ischemia/reperfusion. J Mol Cell Cardiol (2008) 1.11
Skeletal muscle differentiation and fusion are regulated by the BAR-containing Rho-GTPase-activating protein (Rho-GAP), GRAF1. J Biol Chem (2011) 1.11
CASZ1 promotes vascular assembly and morphogenesis through the direct regulation of an EGFL7/RhoA-mediated pathway. Dev Cell (2013) 1.10
Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation. J Biol Chem (2004) 1.06
FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury. Arterioscler Thromb Vasc Biol (2008) 1.04
Fetal-derived adrenomedullin mediates the innate immune milieu of the placenta. J Clin Invest (2013) 0.99
Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation. Arterioscler Thromb Vasc Biol (2010) 0.96
Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth. Circ Res (2009) 0.94
Enhancement of mDia2 activity by Rho-kinase-dependent phosphorylation of the diaphanous autoregulatory domain. Biochem J (2011) 0.91
The LIM protein leupaxin is enriched in smooth muscle and functions as an serum response factor cofactor to induce smooth muscle cell gene transcription. Circ Res (2008) 0.90
Targeted focal adhesion kinase activation in cardiomyocytes protects the heart from ischemia/reperfusion injury. Arterioscler Thromb Vasc Biol (2012) 0.88
Formin homology domain-containing protein 1 regulates smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol (2010) 0.86
SHP-2 acts via ROCK to regulate the cardiac actin cytoskeleton. Development (2012) 0.84
An epigenetic clue to diabetic vascular disease. Circ Res (2008) 0.84
PKA-dependent phosphorylation of serum response factor inhibits smooth muscle-specific gene expression. Arterioscler Thromb Vasc Biol (2009) 0.83
Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature. Arterioscler Thromb Vasc Biol (2011) 0.77
Quantification of myocyte chemotaxis: a role for FAK in regulating directional motility. Methods Mol Biol (2012) 0.77
Germline deletion of FAK-related non-kinase delays post-natal cardiomyocyte mitotic arrest. J Mol Cell Cardiol (2012) 0.76
ROCKs cause SHP-wrecks and broken hearts. Small GTPases (2012) 0.75
Quantifying sphingosine-1-phosphate-dependent activation of the RhoGTPases. Methods Mol Biol (2012) 0.75