Published in Life Sci on June 10, 2008
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The presynaptic component of the serotonergic system is required for clozapine's efficacy. Neuropsychopharmacology (2010) 1.09
Acute administration of typical and atypical antipsychotics reduces EEG γ power, but only the preclinical compound LY379268 reduces the ketamine-induced rise in γ power. Int J Neuropsychopharmacol (2011) 0.93
3-Hydroxykynurenine and clinical symptoms in first-episode neuroleptic-naive patients with schizophrenia. Int J Neuropsychopharmacol (2011) 0.89
Beyond dopamine: glutamate as a target for future antipsychotics. ISRN Pharmacol (2012) 0.86
Subchronic elevation of brain kynurenic acid augments amphetamine-induced locomotor response in mice. J Neural Transm (Vienna) (2011) 0.84
Glutamatergic antipsychotic drugs: a new dawn in the treatment of schizophrenia? Ther Adv Psychopharmacol (2011) 0.83
Divergent acute and chronic modulation of glutamatergic postsynaptic density genes expression by the antipsychotics haloperidol and sertindole. Psychopharmacology (Berl) (2010) 0.81
Behavioral disturbances in adult mice following neonatal virus infection or kynurenine treatment--role of brain kynurenic acid. Brain Behav Immun (2013) 0.79
Glutamatergic neurometabolites in clozapine-responsive and -resistant schizophrenia. Int J Neuropsychopharmacol (2015) 0.79
Role of the NMDA-receptor in Prepulse Inhibition in the Rat. Int J Tryptophan Res (2010) 0.77
Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis. Schizophr Bull (2017) 0.76
Chronic Antipsychotic Treatment in the Rat - Effects on Brain Interleukin-8 and Kynurenic Acid. Int J Tryptophan Res (2015) 0.75
Pharmacogenetic Analysis of Functional Glutamate System Gene Variants and Clinical Response to Clozapine. Mol Neuropsychiatry (2016) 0.75
Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity. Biol Psychiatry (2009) 1.72
Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia. Schizophr Bull (2010) 1.45
Connecting inflammation with glutamate agonism in suicidality. Neuropsychopharmacology (2012) 1.31
Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders. CNS Drugs (2009) 1.30
Reduced D-serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients. Prog Neuropsychopharmacol Biol Psychiatry (2005) 1.24
The kynurenic acid hypothesis of schizophrenia. Physiol Behav (2007) 1.22
Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder. J Psychiatry Neurosci (2010) 1.19
Elevated glutamine/glutamate ratio in cerebrospinal fluid of first episode and drug naive schizophrenic patients. BMC Psychiatry (2005) 1.05
Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine. Synapse (2002) 1.00
GABA(B) receptor-mediated modulation of the firing pattern of ventral tegmental area dopamine neurons in vivo. Naunyn Schmiedebergs Arch Pharmacol (2002) 1.00
Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder. Bipolar Disord (2012) 0.99
Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1-/- mice. Int J Neuropsychopharmacol (2009) 0.99
Effects of COX-1 and COX-2 inhibitors on the firing of rat midbrain dopaminergic neurons--possible involvement of endogenous kynurenic acid. Synapse (2006) 0.96
Elevated levels of kynurenic acid change the dopaminergic response to amphetamine: implications for schizophrenia. Int J Neuropsychopharmacol (2008) 0.95
Induction of the kynurenine pathway by neurotropic influenza A virus infection. J Neurosci Res (2008) 0.94
Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls. J Psychiatry Neurosci (2012) 0.93
Elevation of cerebrospinal fluid interleukin-1ß in bipolar disorder. J Psychiatry Neurosci (2011) 0.92
Prenatal dexamethasone impairs behavior and the activation of the BDNF exon IV promoter in the paraventricular nucleus in adult offspring. Endocrinology (2008) 0.88
Activation of rat ventral tegmental area dopamine neurons by endogenous kynurenic acid: a pharmacological analysis. Neuropharmacology (2007) 0.88
Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts. J Inflamm (Lond) (2011) 0.87
Kynurenic acid and schizophrenia. Adv Exp Med Biol (2003) 0.86
Acyclovir inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct. J Neuroinflammation (2010) 0.85
Altered chemokine levels in the cerebrospinal fluid and plasma of suicide attempters. Psychoneuroendocrinology (2012) 0.85
Subchronic elevation of brain kynurenic acid augments amphetamine-induced locomotor response in mice. J Neural Transm (Vienna) (2011) 0.84
Cerebrospinal fluid kynurenic acid in male and female controls - correlation with monoamine metabolites and influences of confounding factors. J Psychiatr Res (2006) 0.83
Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study. Schizophr Res (2010) 0.82
Inhibitory action of clozapine on rat ventral tegmental area dopamine neurons following increased levels of endogenous kynurenic acid. Neuropsychopharmacology (2003) 0.81
Clozapine modulates midbrain dopamine neuron firing via interaction with the NMDA receptor complex. Synapse (2004) 0.80
Role of the NMDA-receptor in Prepulse Inhibition in the Rat. Int J Tryptophan Res (2010) 0.77
Activation of noradrenergic locus coeruleus neurons by clozapine and haloperidol: involvement of glutamatergic mechanisms. Int J Neuropsychopharmacol (2005) 0.77
Sustained elevation of kynurenic Acid in the cerebrospinal fluid of patients with herpes simplex virus type 1 encephalitis. Int J Tryptophan Res (2013) 0.75
CSF kynurenic acid and suicide risk in schizophrenia spectrum psychosis. Psychiatry Res (2012) 0.75