Temporal heterogeneity in blood supply in human tumor xenografts.

PubWeight™: 0.87‹?›

🔗 View Article (PMC 2435008)

Published in Neoplasia on July 01, 2008

Authors

Kjetil G Brurberg1, Jon-Vidar Gaustad, Camilla S Mollatt, Einar K Rofstad

Author Affiliations

1: Group of Radiation Biology and Tumor Physiology, Department of Radiation Biology, Institute for Cancer Research, Norwegian Radium Hospital, Montebello, Oslo, Norway.

Articles cited by this

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res (1989) 12.85

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst (2001) 8.57

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res (1998) 5.86

Determinants of tumor blood flow: a review. Cancer Res (1988) 5.56

Pathology: cancer cells compress intratumour vessels. Nature (2004) 3.60

Quantification of longitudinal tissue pO2 gradients in window chamber tumours: impact on tumour hypoxia. Br J Cancer (1999) 1.42

Microvascular studies on the origins of perfusion-limited hypoxia. Br J Cancer Suppl (1996) 1.38

Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats. Am J Physiol (1999) 1.36

Orthotopic human melanoma xenograft model systems for studies of tumour angiogenesis, pathophysiology, treatment sensitivity and metastatic pattern. Br J Cancer (1994) 1.36

Physiological noise in murine solid tumours using T2*-weighted gradient-echo imaging: a marker of tumour acute hypoxia? Phys Med Biol (2004) 1.22

Perivascular oxygen tensions in a transplantable mammary tumor growing in a dorsal flap window chamber. Radiat Res (1992) 1.21

Nicotinamide and other benzamide analogs as agents for overcoming hypoxic cell radiation resistance in tumours. A review. Acta Oncol (1995) 1.19

Tumor vascularity assessed by magnetic resonance imaging and intravital microscopy imaging. Neoplasia (2008) 1.15

31P nuclear magnetic resonance spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglobin saturation status and tumor hypoxia. Cancer Res (1988) 1.09

Fluctuations in tumor blood perfusion assessed by dynamic contrast-enhanced MRI. Magn Reson Med (2007) 1.03

A novel method for mapping the heterogeneity in blood supply to normal and malignant tissues in the mouse dorsal window chamber. Microvasc Res (2007) 1.02

Cryospectrophotometric determination of tumor intravascular oxyhemoglobin saturations: dependence on vascular geometry and tumor growth. J Natl Cancer Inst (1988) 0.89

Intratumour heterogeneity in microvessel oxyhaemoglobin saturations. Cancer Lett (2001) 0.81

Microvessel oxyhemoglobin saturation does not reflect tissue oxygen tension in human melanoma xenografts. Microvasc Res (2001) 0.78

Articles by these authors

Dynamic contrast-enhanced magnetic resonance imaging of tumor interstitial fluid pressure. Radiother Oncol (2008) 1.52

Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic dissemination. Int J Cancer (2010) 1.30

Tumor vascularity assessed by magnetic resonance imaging and intravital microscopy imaging. Neoplasia (2008) 1.15

Interstitial fluid pressure and associated lymph node metastasis revealed in tumors by dynamic contrast-enhanced MRI. Cancer Res (2012) 1.13

Assessment of tumor blood perfusion by high-resolution dynamic contrast-enhanced MRI: a preclinical study of human melanoma xenografts. Magn Reson Med (2004) 1.09

Fluctuations in tumor blood perfusion assessed by dynamic contrast-enhanced MRI. Magn Reson Med (2007) 1.03

A novel method for mapping the heterogeneity in blood supply to normal and malignant tissues in the mouse dorsal window chamber. Microvasc Res (2007) 1.02

N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth. Oncogene (2002) 0.99

Fluctuations in pO2 in poorly and well-oxygenated spontaneous canine tumors before and during fractionated radiation therapy. Radiother Oncol (2005) 0.99

Activin A suppresses neuroblastoma xenograft tumor growth via antimitotic and antiangiogenic mechanisms. Cancer Res (2005) 0.99

Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts. BMC Cancer (2012) 0.94

Photochemical internalization of bleomycin is superior to photodynamic therapy due to the therapeutic effect in the tumor periphery. Photochem Photobiol (2008) 0.93

High interstitial fluid pressure is associated with tumor-line specific vascular abnormalities in human melanoma xenografts. PLoS One (2012) 0.91

Radiocurability is associated with interstitial fluid pressure in human tumor xenografts. Neoplasia (2009) 0.91

Tumor-line specific pO(2) fluctuations in human melanoma xenografts. Int J Radiat Oncol Biol Phys (2004) 0.91

Magnetic resonance imaging identifies early effects of sunitinib treatment in human melanoma xenografts. J Exp Clin Cancer Res (2013) 0.91

Assessment of extravascular extracellular space fraction in human melanoma xenografts by DCE-MRI and kinetic modeling. Magn Reson Imaging (2007) 0.91

Assessment of tumor radioresponsiveness and metastatic potential by dynamic contrast-enhanced magnetic resonance imaging. Int J Radiat Oncol Biol Phys (2011) 0.90

Dynamic contrast-enhanced-MRI of tumor hypoxia. Magn Reson Med (2011) 0.89

Human cervical carcinoma xenograft models for studies of the physiological microenvironment of tumors. J Cancer Res Clin Oncol (2009) 0.87

Fluctuations in pO2 in irradiated human melanoma xenografts. Radiat Res (2006) 0.87

Combination of boron neutron capture therapy and external beam radiotherapy for brain tumors. Int J Radiat Oncol Biol Phys (2004) 0.86

Assessment of fraction of hypoxic cells in human tumor xenografts with necrotic regions by dynamic contrast-enhanced MRI. Radiat Res (2008) 0.86

Blood supply in melanoma xenografts is governed by the morphology of the supplying arteries. Neoplasia (2009) 0.86

Dynamic contrast-enhanced magnetic resonance imaging of human melanoma xenografts with necrotic regions. J Magn Reson Imaging (2007) 0.86

Quantitative assessment of uptake and distribution of iron oxide particles (NC100150) in human melanoma xenografts by contrast-enhanced MRI. Magn Reson Med (2004) 0.86

Magnetic resonance imaging of tumor necrosis. Acta Oncol (2010) 0.84

Assessment of hypoxia and radiation response in intramuscular experimental tumors by dynamic contrast-enhanced magnetic resonance imaging. Radiother Oncol (2011) 0.84

Dynamic contrast-enhanced magnetic resonance imaging of tumors: preclinical validation of parametric images. Radiat Res (2009) 0.84

Dynamic contrast-enhanced magnetic resonance imaging of human cervical carcinoma xenografts: pharmacokinetic analysis and correlation to tumor histomorphology. Radiother Oncol (2010) 0.84

pO₂ fluctuation pattern and cycling hypoxia in human cervical carcinoma and melanoma xenografts. Int J Radiat Oncol Biol Phys (2012) 0.83

Quantitative assessment of hypoxia in melanoma xenografts by dynamic contrast-enhanced magnetic resonance imaging: intradermal versus intramuscular tumors. Radiother Oncol (2010) 0.83

Microenvironment-associated lymph node metastasis of human cervical carcinoma xenografts. Acta Oncol (2012) 0.83

Development of hypoxia in a preclinical model of tumor micrometastases. Int J Radiat Oncol Biol Phys (2010) 0.83

Comparison of tumor blood perfusion assessed by dynamic contrast-enhanced MRI with tumor blood supply assessed by invasive imaging. J Magn Reson Imaging (2005) 0.82

Assessment of microvascular density, extracellular volume fraction, and radiobiological hypoxia in human melanoma xenografts by dynamic contrast-enhanced MRI. J Magn Reson Imaging (2007) 0.82

Connective tissue of cervical carcinoma xenografts: associations with tumor hypoxia and interstitial fluid pressure and its assessment by DCE-MRI and DW-MRI. Acta Oncol (2013) 0.82

The Microenvironment of Cervical Carcinoma Xenografts: Associations with Lymph Node Metastasis and Its Assessment by DCE-MRI. Transl Oncol (2013) 0.82

Assessment of fraction of radiobiologically hypoxic cells in human melanoma xenografts by dynamic contrast-enhanced MRI. Magn Reson Med (2006) 0.81

Assessment of the interstitial fluid pressure of tumors by dynamic contrast-enhanced magnetic resonance imaging with contrast agents of different molecular weights. Acta Oncol (2012) 0.81

Differentiation between hypoxic and non-hypoxic experimental tumors by dynamic contrast-enhanced magnetic resonance imaging. Radiother Oncol (2011) 0.81

Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of tumors: a preclinical study of cervical carcinoma and melanoma xenografts. Acta Oncol (2012) 0.81

Evaluating antigen targeting and anti-tumor activity of a new anti-CD37 radioimmunoconjugate against non-Hodgkin's lymphoma. Anticancer Res (2013) 0.80

Changes in intratumor heterogeneity in blood perfusion in intradermal human melanoma xenografts during tumor growth assessed by DCE-MRI. Magn Reson Imaging (2005) 0.80

Neutron capture therapy of intracerebral melanoma: enhanced survival and cure after blood-brain barrier opening to improve delivery of boronophenylalanine. Int J Radiat Oncol Biol Phys (2002) 0.79

Preclinical evaluation of Gd-DTPA and gadomelitol as contrast agents in DCE-MRI of cervical carcinoma interstitial fluid pressure. BMC Cancer (2012) 0.79

Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of melanoma xenografts. Int J Radiat Oncol Biol Phys (2012) 0.78

Intratumor heterogeneity in blood perfusion in orthotopic human melanoma xenografts assessed by dynamic contrast-enhanced magnetic resonance imaging. J Magn Reson Imaging (2005) 0.78

Detection of different hypoxic cell subpopulations in human melanoma xenografts by pimonidazole immunohistochemistry. Radiat Res (2008) 0.77

Assessment of tumor hypoxia and interstitial fluid pressure by gadomelitol-based dynamic contrast-enhanced magnetic resonance imaging. Radiother Oncol (2011) 0.77

The efficacy of CHK1 inhibitors is not altered by hypoxia, but is enhanced after reoxygenation. Mol Cancer Ther (2013) 0.77

Assessment of hypoxia in human cervical carcinoma xenografts by dynamic contrast-enhanced magnetic resonance imaging. Int J Radiat Oncol Biol Phys (2009) 0.76

Vascular abnormalities associated with acute hypoxia in human melanoma xenografts. Radiother Oncol (2012) 0.76

Limitations of dynamic contrast-enhanced MRI in monitoring radiation-induced changes in the fraction of radiobiologically hypoxic cells in human melanoma xenografts. J Magn Reson Imaging (2008) 0.76

Tumors exposed to acute cyclic hypoxia show increased vessel density and delayed blood supply. Microvasc Res (2012) 0.76

Interstitial fluid pressure and vascularity of intradermal and intramuscular human tumor xenografts. Int J Radiat Oncol Biol Phys (2011) 0.76

Tumor-line specific causes of intertumor heterogeneity in blood supply in human melanoma xenografts. Microvasc Res (2012) 0.76

A novel application of dorsal window chambers: repetitive imaging of tumor-associated lymphatics. Microvasc Res (2012) 0.75