Published in BMC Bioinformatics on July 03, 2008
Emergence of scaling in random networks Science (1999) 89.38
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature (2000) 47.15
Network biology: understanding the cell's functional organization. Nat Rev Genet (2004) 36.62
Network motifs: simple building blocks of complex networks. Science (2002) 35.80
A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci U S A (2001) 33.71
Lethality and centrality in protein networks. Nature (2001) 29.64
Error and attack tolerance of complex networks Nature (2000) 27.90
The large-scale organization of metabolic networks. Nature (2000) 27.57
Comparative assessment of large-scale data sets of protein-protein interactions. Nature (2002) 24.25
The Database of Interacting Proteins: 2004 update. Nucleic Acids Res (2004) 23.67
Specificity and stability in topology of protein networks. Science (2002) 21.07
A protein interaction map of Drosophila melanogaster. Science (2003) 20.06
A human protein-protein interaction network: a resource for annotating the proteome. Cell (2005) 18.97
A map of the interactome network of the metazoan C. elegans. Science (2004) 15.60
Evidence for dynamically organized modularity in the yeast protein-protein interaction network. Nature (2004) 13.27
Inferring genetic networks and identifying compound mode of action via expression profiling. Science (2003) 9.10
Superfamilies of evolved and designed networks. Science (2004) 8.12
Protein interactions: two methods for assessment of the reliability of high throughput observations. Mol Cell Proteomics (2002) 8.11
Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets. Nat Genet (2006) 6.74
Self-similarity of complex networks. Nature (2005) 6.13
Gaining confidence in high-throughput protein interaction networks. Nat Biotechnol (2003) 5.15
Herpesviral protein networks and their interaction with the human proteome. Science (2005) 4.74
Effect of sampling on topology predictions of protein-protein interaction networks. Nat Biotechnol (2005) 4.16
A bottom-up approach to gene regulation. Nature (2006) 4.03
Subnets of scale-free networks are not scale-free: sampling properties of networks. Proc Natl Acad Sci U S A (2005) 3.75
A first-draft human protein-interaction map. Genome Biol (2004) 3.64
Formation of regulatory patterns during signal propagation in a Mammalian cellular network. Science (2005) 3.48
Modeling interactome: scale-free or geometric? Bioinformatics (2004) 3.20
Topological units of environmental signal processing in the transcriptional regulatory network of Escherichia coli. Proc Natl Acad Sci U S A (2005) 2.84
Potential artefacts in protein-interaction networks. FEBS Lett (2002) 2.24
The "robust yet fragile" nature of the Internet. Proc Natl Acad Sci U S A (2005) 2.04
The topological relationship between the large-scale attributes and local interaction patterns of complex networks. Proc Natl Acad Sci U S A (2004) 2.02
A simple physical model for scaling in protein-protein interaction networks. Proc Natl Acad Sci U S A (2005) 1.78
How scale-free are biological networks. J Comput Biol (2006) 1.62
Some protein interaction data do not exhibit power law statistics. FEBS Lett (2005) 1.32
Statistical properties of sampled networks. Phys Rev E Stat Nonlin Soft Matter Phys (2006) 1.30
Sampling properties of random graphs: the degree distribution. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 1.11
Protein interaction networks beyond artifacts. FEBS Lett (2002) 1.04
Free-energy distribution of binary protein-protein binding suggests cross-species interactome differences. Proc Natl Acad Sci U S A (2006) 0.85
Hysteresis and cell cycle transitions: how crucial is it? Biophys J (2004) 0.83
Statistical properties of sampled networks by random walks. Phys Rev E Stat Nonlin Soft Matter Phys (2007) 0.80
Dynamical advantages of scale-free networks. Phys Rev Lett (2006) 0.77
The minimum information about a proteomics experiment (MIAPE). Nat Biotechnol (2007) 10.24
A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates. Biophys J (2008) 4.22
From pulsus to pulseless: the saga of cardiac alternans. Circ Res (2006) 3.83
Action potential duration restitution and alternans in rabbit ventricular myocytes: the key role of intracellular calcium cycling. Circ Res (2005) 2.89
The dynamics of cardiac fibrillation. Circulation (2005) 2.58
So little source, so much sink: requirements for afterdepolarizations to propagate in tissue. Biophys J (2010) 2.57
Oxidative-stress-induced afterdepolarizations and calmodulin kinase II signaling. Circ Res (2008) 2.54
Target identification using drug affinity responsive target stability (DARTS). Proc Natl Acad Sci U S A (2009) 2.40
Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias. Proc Natl Acad Sci U S A (2009) 2.35
Quinones and aromatic chemical compounds in particulate matter induce mitochondrial dysfunction: implications for ultrafine particle toxicity. Environ Health Perspect (2004) 2.09
Effects of fibroblast-myocyte coupling on cardiac conduction and vulnerability to reentry: A computational study. Heart Rhythm (2009) 2.05
Mitochondria and ischemia/reperfusion injury. Ann N Y Acad Sci (2005) 2.01
Diastolic intracellular calcium-membrane voltage coupling gain and postshock arrhythmias: role of purkinje fibers and triggered activity. Circ Res (2009) 1.96
Bidirectional ventricular tachycardia: ping pong in the His-Purkinje system. Heart Rhythm (2010) 1.94
Intracellular calcium dynamics and acceleration of sinus rhythm by beta-adrenergic stimulation. Circulation (2009) 1.91
Mechanisms of recurrent ventricular fibrillation in a rabbit model of pacing-induced heart failure. Heart Rhythm (2009) 1.89
Early afterdepolarizations and cardiac arrhythmias. Heart Rhythm (2010) 1.86
Arrhythmogenic consequences of myofibroblast-myocyte coupling. Cardiovasc Res (2011) 1.82
Calsequestrin-mediated mechanism for cellular calcium transient alternans. Biophys J (2008) 1.77
Intracellular calcium cycling, early afterdepolarizations, and reentry in simulated long QT syndrome. Heart Rhythm (2004) 1.75
Bi-stable wave propagation and early afterdepolarization-mediated cardiac arrhythmias. Heart Rhythm (2011) 1.71
A simulation study of the effects of cardiac anatomy in ventricular fibrillation. J Clin Invest (2004) 1.70
Divergent mitochondrial biogenesis responses in human cardiomyopathy. Circulation (2013) 1.69
Spatially discordant alternans in cardiac tissue: role of calcium cycling. Circ Res (2006) 1.66
Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles. Circ Res (2011) 1.66
Intracellular Ca dynamics in ventricular fibrillation. Am J Physiol Heart Circ Physiol (2004) 1.62
Bifurcation and chaos in a model of cardiac early afterdepolarizations. Phys Rev Lett (2009) 1.60
Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress. Am J Physiol Heart Circ Physiol (2009) 1.59
Regulation of the mammalian cell cycle: a model of the G1-to-S transition. Am J Physiol Cell Physiol (2002) 1.58
Coexistence of two types of ventricular fibrillation during acute regional ischemia in rabbit ventricle. J Cardiovasc Electrophysiol (2004) 1.53
Superiority of biphasic over monophasic defibrillation shocks is attributable to less intracellular calcium transient heterogeneity. J Am Coll Cardiol (2008) 1.52
Alternans and arrhythmias: from cell to heart. Circ Res (2011) 1.52
Protection of cardiac mitochondria by diazoxide and protein kinase C: implications for ischemic preconditioning. Proc Natl Acad Sci U S A (2002) 1.51
Deranged sodium to sudden death. J Physiol (2015) 1.51
Systematic characterization of the murine mitochondrial proteome using functionally validated cardiac mitochondria. Proteomics (2008) 1.51
Nitric oxide donors protect murine myocardium against infarction via modulation of mitochondrial permeability transition. Am J Physiol Heart Circ Physiol (2004) 1.51
Dynamics of the cell cycle: checkpoints, sizers, and timers. Biophys J (2003) 1.47
Two types of ventricular fibrillation in isolated rabbit hearts: importance of excitability and action potential duration restitution. Circulation (2002) 1.46
Systems biology approaches to metabolic and cardiovascular disorders: network perspectives of cardiovascular metabolism. J Lipid Res (2006) 1.46
Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins: complimentary separation techniques with LC/MS/MS. Mol Cell Proteomics (2002) 1.44
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome (2012) 1.43
Arrhythmogenic consequences of intracellular calcium waves. Am J Physiol Heart Circ Physiol (2009) 1.42
Pro- and antiarrhythmic effects of ATP-sensitive potassium current activation on reentry during early afterdepolarization-mediated arrhythmias. Heart Rhythm (2012) 1.42
Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes. J Cell Biol (2011) 1.42
Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria. Mol Cell Proteomics (2010) 1.41
Muscle mechanoreceptor sensitivity in heart failure. Am J Physiol Heart Circ Physiol (2004) 1.41
Mechanism for spiral wave breakup in excitable and oscillatory media. Phys Rev Lett (2003) 1.40
Low serum total cholesterol is associated with marked increase in mortality in advanced heart failure. J Card Fail (2002) 1.40
Spermine block of the strong inward rectifier potassium channel Kir2.1: dual roles of surface charge screening and pore block. J Gen Physiol (2002) 1.39
Spark-induced sparks as a mechanism of intracellular calcium alternans in cardiac myocytes. Circ Res (2010) 1.38
Spontaneous atrial fibrillation initiated by triggered activity near the pulmonary veins in aged rats subjected to glycolytic inhibition. Am J Physiol Heart Circ Physiol (2006) 1.37
Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells. J Clin Invest (2009) 1.36
Intracellular calcium and vulnerability to fibrillation and defibrillation in Langendorff-perfused rabbit ventricles. Circulation (2006) 1.34
Formation of protein kinase C(epsilon)-Lck signaling modules confers cardioprotection. J Clin Invest (2002) 1.34
Dynamic origin of spatially discordant alternans in cardiac tissue. Biophys J (2006) 1.33
Cardiac alternans induced by fibroblast-myocyte coupling: mechanistic insights from computational models. Am J Physiol Heart Circ Physiol (2009) 1.33
Subcellular localization of hexokinases I and II directs the metabolic fate of glucose. PLoS One (2011) 1.32
Inward rectification by polyamines in mouse Kir2.1 channels: synergy between blocking components. J Physiol (2003) 1.30
Suppression of re-entrant and multifocal ventricular fibrillation by the late sodium current blocker ranolazine. J Am Coll Cardiol (2011) 1.30
Intracellular Ca alternans: coordinated regulation by sarcoplasmic reticulum release, uptake, and leak. Biophys J (2008) 1.30
Modifying L-type calcium current kinetics: consequences for cardiac excitation and arrhythmia dynamics. Biophys J (2008) 1.30
Collagen IV induces trophoectoderm differentiation of mouse embryonic stem cells. Stem Cells (2007) 1.30
Cardiovascular networks: systems-based approaches to cardiovascular disease. Circulation (2010) 1.30
Irregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos? Biophys J (2010) 1.29
Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. J Clin Invest (2010) 1.28
A tale of two fibrillations. Circulation (2003) 1.25
Reactive oxygen species production in energized cardiac mitochondria during hypoxia/reoxygenation: modulation by nitric oxide. Circ Res (2008) 1.24
Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve. Cardiovasc Res (2013) 1.23
Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity. J Physiol (2008) 1.22
Differential conditions for early after-depolarizations and triggered activity in cardiomyocytes derived from transgenic LQT1 and LQT2 rabbits. J Physiol (2011) 1.21
Spatially discordant alternans in cardiomyocyte monolayers. Am J Physiol Heart Circ Physiol (2008) 1.19
Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation (2008) 1.17
Altered proteome biology of cardiac mitochondria under stress conditions. J Proteome Res (2008) 1.16
Adipose tissue-derived cells improve cardiac function following myocardial infarction. J Surg Res (2008) 1.16