Published in DNA Repair (Amst) on July 17, 2008
An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature (2012) 2.35
NF-κB inhibition delays DNA damage-induced senescence and aging in mice. J Clin Invest (2012) 1.91
The oxidative DNA lesions 8,5'-cyclopurines accumulate with aging in a tissue-specific manner. Aging Cell (2012) 1.30
Accumulation of (5'S)-8,5'-cyclo-2'-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice. DNA Repair (Amst) (2008) 1.19
A quantitative assay for assessing the effects of DNA lesions on transcription. Nat Chem Biol (2012) 1.16
Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proc Natl Acad Sci U S A (2012) 1.13
Mitochondrial DNA damage and its consequences for mitochondrial gene expression. Biochim Biophys Acta (2012) 1.12
Structure of (5'S)-8,5'-cyclo-2'-deoxyguanosine in DNA. J Am Chem Soc (2011) 1.11
(5'S)-8,5'-cyclo-2'-deoxyguanosine is a strong block to replication, a potent pol V-dependent mutagenic lesion, and is inefficiently repaired in Escherichia coli. Biochemistry (2011) 1.08
Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines. Biochemistry (2010) 1.05
Translesion synthesis of 8,5'-cyclopurine-2'-deoxynucleosides by DNA polymerases η, ι, and ζ. J Biol Chem (2013) 1.03
Stress-induced DNA damage biomarkers: applications and limitations. Front Chem (2015) 0.94
Structural basis for the recognition of diastereomeric 5',8-cyclo-2'-deoxypurine lesions by the human nucleotide excision repair system. Nucleic Acids Res (2014) 0.92
Repair efficiency of (5'S)-8,5'-cyclo-2'-deoxyguanosine and (5'S)-8,5'-cyclo-2'-deoxyadenosine depends on the complementary base. DNA Repair (Amst) (2012) 0.92
Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide. Chem Res Toxicol (2011) 0.88
A 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase β. Nucleic Acids Res (2014) 0.87
Structures of (5'S)-8,5'-Cyclo-2'-deoxyguanosine Mismatched with dA or dT. Chem Res Toxicol (2012) 0.86
Stability of N-glycosidic bond of (5'S)-8,5'-cyclo-2'-deoxyguanosine. Chem Res Toxicol (2012) 0.83
Induction of 8,5'-cyclo-2'-deoxyadenosine and 8,5'-cyclo-2'-deoxyguanosine in isolated DNA by Fenton-type reagents. Chem Res Toxicol (2013) 0.82
Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions. Proc Natl Acad Sci U S A (2015) 0.81
Accurate and efficient bypass of 8,5'-cyclopurine-2'-deoxynucleosides by human and yeast DNA polymerase η. Chem Res Toxicol (2012) 0.81
Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replication of (5'S)-8,5'-cyclopurine-2'-deoxynucleosides in vitro by DNA polymerase IV, exo-free Klenow fragment, and Dpo4. Chem Res Toxicol (2014) 0.81
In vivo detection and replication studies of α-anomeric lesions of 2'-deoxyribonucleosides. Nucleic Acids Res (2015) 0.81
RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications. Crit Rev Biochem Mol Biol (2015) 0.80
Close encounters for the first time: Helicase interactions with DNA damage. DNA Repair (Amst) (2015) 0.80
Impact of age-associated cyclopurine lesions on DNA repair helicases. PLoS One (2014) 0.79
Removal of reactive oxygen species-induced 3'-blocked ends by XPF-ERCC1. Chem Res Toxicol (2011) 0.79
Effects of tet-induced oxidation products of 5-methylcytosine on DNA replication in mammalian cells. Chem Res Toxicol (2014) 0.78
Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage. Chem Res Toxicol (2016) 0.78
Removal of oxidatively generated DNA damage by overlapping repair pathways. Free Radic Biol Med (2016) 0.78
Oxidatively Generated Guanine(C8)-Thymine(N3) Intrastrand Cross-links in Double-stranded DNA Are Repaired by Base Excision Repair Pathways. J Biol Chem (2015) 0.77
Generation of guanine-amino acid cross-links by a free radical combination mechanism. Phys Chem Chem Phys (2014) 0.76
Synthesis of [1,3, NH2-(15)N3] (5'S)-8,5'-cyclo-2'-deoxyguanosine. J Labelled Comp Radiopharm (2013) 0.75
Detection of Bulky Endogenous Oxidative DNA Lesions Derived from 8,5'-Cyclo-2'-deoxyadenosine by 32P-Postlabeling Assay. Curr Protoc Toxicol (2015) 0.75
Bypass of a 5',8-cyclopurine-2'-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks. DNA Repair (Amst) (2015) 0.75
Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J (2003) 7.21
Oxidative DNA damage and disease: induction, repair and significance. Mutat Res (2004) 3.54
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA. Proc Natl Acad Sci U S A (2002) 3.33
Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes. J Biol Chem (2005) 1.64
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo. Proc Natl Acad Sci U S A (2010) 1.61
New functions of XPC in the protection of human skin cells from oxidative damage. EMBO J (2006) 1.60
Regulation of reactive oxygen species, DNA damage, and c-Myc function by peroxiredoxin 1. Oncogene (2005) 1.57
Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress. FASEB J (2003) 1.38
Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA. Biochemistry (2004) 1.32
Linking uracil base excision repair and 5-fluorouracil toxicity in yeast. Nucleic Acids Res (2006) 1.29
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145. Carcinogenesis (2004) 1.29
Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA. DNA Repair (Amst) (2009) 1.24
The cockayne syndrome group B gene product is involved in cellular repair of 8-hydroxyadenine in DNA. J Biol Chem (2002) 1.22
Accumulation of (5'S)-8,5'-cyclo-2'-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice. DNA Repair (Amst) (2008) 1.19
DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine). J Am Chem Soc (2003) 1.13
Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase. J Biol Chem (2009) 1.12
Human polymorphic variants of the NEIL1 DNA glycosylase. J Biol Chem (2007) 1.10
Complete release of (5'S)-8,5'-cyclo-2'-deoxyadenosine from dinucleotides, oligodeoxynucleotides and DNA, and direct comparison of its levels in cellular DNA with other oxidatively induced DNA lesions. Nucleic Acids Res (2004) 1.09
Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines. Biochemistry (2010) 1.05
Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehyde. Nucleic Acids Res (2005) 1.04
Copper oxide nanoparticle mediated DNA damage in terrestrial plant models. Environ Sci Technol (2012) 1.02
Measurement of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines in DNA in vivo by liquid chromatography/isotope-dilution tandem mass spectrometry. Biochem Biophys Res Commun (2009) 1.01
Lymphoblasts of women with BRCA1 mutations are deficient in cellular repair of 8,5'-Cyclopurine-2'-deoxynucleosides and 8-hydroxy-2'-deoxyguanosine. Biochemistry (2007) 1.01
Mass spectrometric assays for the tandem lesion 8,5'-cyclo-2'-deoxyguanosine in mammalian DNA. Biochemistry (2002) 1.01
Oxidized guanine lesions and hOgg1 activity in lung cancer. Oncogene (2005) 0.96
Oxidative DNA damage in polymorphonuclear leukocytes of patients with familial Mediterranean fever. Free Radic Biol Med (2007) 0.96
Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break. Radiat Res (2006) 0.96
Determination of active site residues in Escherichia coli endonuclease VIII. J Biol Chem (2001) 0.96
The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts. DNA Repair (Amst) (2009) 0.93
Accumulation of oxidatively induced DNA damage in human breast cancer cell lines following treatment with hydrogen peroxide. Cell Cycle (2007) 0.93
A major role for nonenzymatic antioxidant processes in the radioresistance of Halobacterium salinarum. J Bacteriol (2011) 0.93
Measurement of formamidopyrimidines in DNA. Free Radic Biol Med (2008) 0.92
Oxidative changes in the DNA of stroma and epithelium from the female breast: potential implications for breast cancer. Cell Cycle (2006) 0.92
Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases. DNA Repair (Amst) (2009) 0.91
Overexpression and rapid purification of Escherichia coli formamidopyrimidine-DNA glycosylase. Protein Expr Purif (2004) 0.89
The oxidatively induced DNA lesions 8,5'-cyclo-2'-deoxyadenosine and 8-hydroxy-2'-deoxyadenosine are strongly resistant to acid-induced hydrolysis of the glycosidic bond. Mech Ageing Dev (2007) 0.87
Reduced repair of 8-hydroxyguanine in the human breast cancer cell line, HCC1937. BMC Cancer (2006) 0.86
Arabidopsis thaliana Ogg1 protein excises 8-hydroxyguanine and 2,6-diamino-4-hydroxy-5-formamidopyrimidine from oxidatively damaged DNA containing multiple lesions. Biochemistry (2003) 0.86
Chlorella virus pyrimidine dimer glycosylase excises ultraviolet radiation- and hydroxyl radical-induced products 4,6-diamino-5-formamidopyrimidine and 2,6-diamino-4-hydroxy-5-formamidopyrimidine from DNA. Photochem Photobiol (2002) 0.84
Glutathione depletion by buthionine sulfoximine induces oxidative damage to DNA in organs of rabbits in vivo. Biochemistry (2009) 0.84
DNA damage products (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines as potential biomarkers in human urine for atherosclerosis. Biochemistry (2012) 0.84
Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase. FEBS J (2009) 0.84
Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine. DNA Repair (Amst) (2012) 0.84
Biomarkers signal contaminant effects on the organs of English sole (Parophrys vetulus) from Puget Sound. Environ Health Perspect (2006) 0.83
Identification and quantification of human DNA repair protein NEIL1 by liquid chromatography/isotope-dilution tandem mass spectrometry. J Proteome Res (2013) 0.83
Identification and quantification of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines in human urine as putative biomarkers of oxidatively induced damage to DNA. Biochem Biophys Res Commun (2010) 0.83
Evidence for upregulated repair of oxidatively induced DNA damage in human colorectal cancer. DNA Repair (Amst) (2011) 0.81
Protective roles of single-wall carbon nanotubes in ultrasonication-induced DNA base damage. Small (2012) 0.80
Structural alterations in breast stromal and epithelial DNA: the influence of 8,5'-cyclo-2'-deoxyadenosine. Cell Cycle (2006) 0.79
Measurement of DNA biomarkers for the safety of tissue-engineered medical products, using artificial skin as a model. Tissue Eng (2004) 0.78
Combined Effects of High-Dose Bisphenol A and Oxidizing Agent (KBrO3) on Cellular Microenvironment, Gene Expression, and Chromatin Structure of Ku70-deficient Mouse Embryonic Fibroblasts. Environ Health Perspect (2016) 0.76
Stable isotope-labeling of DNA repair proteins, and their purification and characterization. Protein Expr Purif (2011) 0.76
Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A. J Inorg Biochem (2003) 0.76
RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria. Free Radic Biol Med (2012) 0.76
Identification and quantification of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in human cells by liquid chromatography/isotope-dilution tandem mass spectrometry. PLoS One (2013) 0.75