Published in Chembiochem on August 11, 2008
The Standard European Vector Architecture (SEVA): a coherent platform for the analysis and deployment of complex prokaryotic phenotypes. Nucleic Acids Res (2012) 1.42
Engineering ligand-responsive gene-control elements: lessons learned from natural riboswitches. Gene Ther (2009) 1.11
De novo design of a synthetic riboswitch that regulates transcription termination. Nucleic Acids Res (2012) 1.07
Artificial riboswitches for gene expression and replication control of DNA and RNA viruses. Proc Natl Acad Sci U S A (2014) 0.96
An engineered small RNA-mediated genetic switch based on a ribozyme expression platform. Nucleic Acids Res (2013) 0.90
Riboswitch detection using profile hidden Markov models. BMC Bioinformatics (2009) 0.88
Thermozymes: Synthetic RNA thermometers based on ribozyme activity. RNA Biol (2013) 0.84
Basis for ligand discrimination between ON and OFF state riboswitch conformations: the case of the SAM-I riboswitch. RNA (2012) 0.79
Conformational heterogeneity of the SAM-I riboswitch transcriptional ON state: a chaperone-like role for S-adenosyl methionine. J Mol Biol (2012) 0.78
Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy. Chem Rev (2007) 2.90
Improved aptazyme design and in vivo screening enable riboswitching in bacteria. Angew Chem Int Ed Engl (2008) 1.76
RNA quadruplex-based modulation of gene expression. Chem Biol (2007) 1.64
Aptamer displacement identifies alternative small-molecule target sites that escape viral resistance. Chem Biol (2007) 1.52
A comparison of DNA and RNA quadruplex structures and stabilities. Bioorg Med Chem (2009) 1.30
Artificial ribozyme switches containing natural riboswitch aptamer domains. Angew Chem Int Ed Engl (2009) 1.27
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes. Nucleic Acids Res (2009) 1.11
A ligand-dependent hammerhead ribozyme switch for controlling mammalian gene expression. Mol Biosyst (2010) 1.10
Comparative investigation of the genomic regions involved in antigenic variation of the TprK antigen among treponemal species, subspecies, and strains. J Bacteriol (2012) 1.05
Artificial riboswitches for gene expression and replication control of DNA and RNA viruses. Proc Natl Acad Sci U S A (2014) 0.96
Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses. Nucleic Acids Res (2012) 0.93
RNA quadruplexes. Met Ions Life Sci (2011) 0.92
Efficient suppression of gene expression by targeting 5'-UTR-based RNA quadruplexes with bisquinolinium compounds. Chembiochem (2011) 0.90
An engineered small RNA-mediated genetic switch based on a ribozyme expression platform. Nucleic Acids Res (2013) 0.90
Human telomeric quadruplex conformations studied by pulsed EPR. Angew Chem Int Ed Engl (2009) 0.89
Turning inhibitors into activators: a hammerhead ribozyme controlled by a guanine quadruplex. Angew Chem Int Ed Engl (2006) 0.87
Conformations of individual quadruplex units studied in the context of extended human telomeric DNA. Chem Commun (Camb) (2012) 0.87
A new anticoagulant-antidote pair: control of thrombin activity by aptamers and porphyrins. J Am Chem Soc (2007) 0.87
Aptazyme-mediated regulation of 16S ribosomal RNA. Chem Biol (2010) 0.87
Redesigned tetrads with altered hydrogen bonding patterns enable programming of quadruplex topologies. Chem Commun (Camb) (2008) 0.86
A matter of location: influence of G-quadruplexes on Escherichia coli gene expression. Chem Biol (2014) 0.86
Inhibition of dicing of guanosine-rich shRNAs by quadruplex-binding compounds. Chembiochem (2008) 0.86
Investigation of mRNA quadruplex formation in Escherichia coli. Nat Protoc (2009) 0.85
Thermozymes: Synthetic RNA thermometers based on ribozyme activity. RNA Biol (2013) 0.84
Small molecule-triggered assembly of DNA nanoarchitectures. Chem Commun (Camb) (2010) 0.84
Identification of novel quadruplex ligands from small molecule libraries by FRET-based high-throughput screening. Chembiochem (2011) 0.84
Novel DNA catalysts based on G-quadruplex recognition. Chembiochem (2008) 0.82
Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines. BMC Res Notes (2012) 0.82
Expanded hammerhead ribozymes containing addressable three-way junctions. RNA (2009) 0.81
Post-transcriptional Boolean computation by combining aptazymes controlling mRNA translation initiation and tRNA activation. Mol Biosyst (2012) 0.81
Intracellular conformations of human telomeric quadruplexes studied by electron paramagnetic resonance spectroscopy. Chemphyschem (2012) 0.81
Long-range distance determination in a DNA model system inside Xenopus laevis oocytes by in-cell spin-label EPR. Chembiochem (2011) 0.80
Small-molecule-dependent regulation of transfer RNA in bacteria. Angew Chem Int Ed Engl (2009) 0.80
Reporter assays for studying quadruplex nucleic acids. Methods (2012) 0.80
Small-molecule-triggered manipulation of DNA three-way junctions. J Am Chem Soc (2011) 0.79
G quadruplexes stabilised by 8-oxo-2'-deoxyguanosine. Chemistry (2011) 0.79
Site-directed spin-labeling of nucleotides and the use of in-cell EPR to determine long-range distances in a biologically relevant environment. Nat Protoc (2012) 0.78
Engineering aptazyme switches for conditional gene expression in mammalian cells utilizing an in vivo screening approach. Methods Mol Biol (2015) 0.78
Ribozyme-based transfer RNA switches for post-transcriptional control of amino acid identity in protein synthesis. J Am Chem Soc (2013) 0.77
In vivo screening for aptazyme-based bacterial riboswitches. Methods Mol Biol (2014) 0.76
Pulsed EPR spectroscopy distance measurements of DNA internally labelled with Gd(3+)-DOTA. Chem Commun (Camb) (2015) 0.75
Pyrene modification leads to increased catalytic activity in minimal hammerhead ribozymes. Chem Commun (Camb) (2007) 0.75
Structural characterization of quadruplex DNA with in-cell EPR approaches. Bioorg Med Chem (2013) 0.75
In vivo screening of ligand-dependent hammerhead ribozymes. Methods Mol Biol (2012) 0.75