Published in Org Lett on July 09, 2008
Design and syntheses of novel N'-((4-oxo-4H-chromen-3-yl)methylene)benzohydrazide as inhibitors of cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase. Bioorg Med Chem (2013) 2.43
PTEN regulates collagen-induced platelet activation. Blood (2010) 1.60
Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. Cell (2003) 1.57
Possible genomic imprinting of three human obesity-related genetic loci. Am J Hum Genet (2005) 1.54
A prototype of giant magnetoimpedance-based biosensing system for targeted detection of gastric cancer cells. Biosens Bioelectron (2010) 1.49
Reuse of infected cardiac rhythm management devices in the same patients: a single-center experience. Pacing Clin Electrophysiol (2014) 1.40
Targeting autophagy potentiates chemotherapy-induced apoptosis and proliferation inhibition in hepatocarcinoma cells. Cancer Lett (2012) 1.36
MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway. J Biol Chem (2012) 1.31
Interacting genetic loci on chromosomes 20 and 10 influence extreme human obesity. Am J Hum Genet (2002) 1.21
Electrostatic gating of a nanometer water channel. Proc Natl Acad Sci U S A (2007) 1.19
Reversal of multidrug resistance in cancer cells by pyranocoumarins isolated from Radix Peucedani. Eur J Pharmacol (2003) 1.17
A novel DNA topoisomerase I inhibitor with different mechanism from camptothecin induces G2/M phase cell cycle arrest to K562 cells. Biochemistry (2010) 1.12
A microarray-based gastric carcinoma prewarning system. World J Gastroenterol (2005) 1.08
Detection of hepatitis B virus DNA by real-time PCR using TaqMan-MGB probe technology. World J Gastroenterol (2005) 1.02
A CCD-based reader combined quantum dots-labeled lateral flow strips for ultrasensitive quantitative detection of anti-HBs antibody. J Biomed Nanotechnol (2012) 1.02
Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site. J Biol Chem (2004) 0.99
Linkage and linkage disequilibrium mapping of genes influencing human obesity in chromosome region 7q22.1-7q35. Diabetes (2003) 0.98
A novel quantum dots-based point of care test for syphilis. Nanoscale Res Lett (2010) 0.98
PDK1 regulates platelet activation and arterial thrombosis. Blood (2013) 0.96
A genome scan for serum triglyceride in obese nuclear families. J Lipid Res (2004) 0.96
Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria. J Med Chem (2008) 0.95
Inhibition of autophagy enhances anticancer effects of bevacizumab in hepatocarcinoma. J Mol Med (Berl) (2012) 0.94
Interaction between obesity-susceptibility loci in chromosome regions 2p25-p24 and 13q13-q21. Eur J Hum Genet (2005) 0.94
Autophagy in hypoxia protects cancer cells against apoptosis induced by nutrient deprivation through a Beclin1-dependent way in hepatocellular carcinoma. J Cell Biochem (2011) 0.93
Turning off transcription of the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindoline derivatives. J Med Chem (2010) 0.93
Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand. Bioorg Med Chem Lett (2010) 0.92
An obesity-related locus in chromosome region 12q23-24. Diabetes (2004) 0.92
Hybrid Cu(x)O/TiO₂ nanocomposites as risk-reduction materials in indoor environments. ACS Nano (2012) 0.91
A Quick and Parallel Analytical Method Based on Quantum Dots Labeling for ToRCH-Related Antibodies. Nanoscale Res Lett (2009) 0.90
Understanding the electronic energy transfer pathways in the trimeric and hexameric aggregation state of cyanobacteria phycocyanin within the framework of Förster theory. J Comput Chem (2013) 0.87
Laryngeal reinnervation using ansa cervicalis for thyroid surgery-related unilateral vocal fold paralysis: a long-term outcome analysis of 237 cases. PLoS One (2011) 0.87
Absolute quantification of plasmid DNA by real-time PCR with genomic DNA as external standard and its application to a biodistribution study of an HIV DNA vaccine. Anal Sci (2009) 0.86
Characterization of mitochondrial trifunctional protein and its inactivation study for medicine development. Biochim Biophys Acta (2008) 0.86
A silicon dioxide modified magnetic nanoparticles-labeled lateral flow strips for HBs antigen. J Biomed Nanotechnol (2011) 0.85
Intrinsic enoyl-CoA isomerase activity of rat acyl-CoA oxidase I. Biochim Biophys Acta (2005) 0.84
Stabilization of G-quadruplex DNA by C-5-methyl-cytosine in bcl-2 promoter: implications for epigenetic regulation. Biochem Biophys Res Commun (2012) 0.84
Platelet P2Y12 is involved in murine pulmonary metastasis. PLoS One (2013) 0.84
Implantable defibrillator lead extraction with optimized standard extraction techniques. J Geriatr Cardiol (2013) 0.83
Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors. Eur J Med Chem (2011) 0.83
Mutation and inhibition studies of mevalonate 5-diphosphate decarboxylase. Bioorg Med Chem Lett (2007) 0.83
Inhibition of cell proliferation by quindoline derivative (SYUIQ-05) through its preferential interaction with c-myc promoter G-quadruplex. J Med Chem (2011) 0.83
Glycemic variability is associated with subclinical atherosclerosis in Chinese type 2 diabetic patients. Cardiovasc Diabetol (2013) 0.83
A quantitative trait locus influencing fasting plasma glucose in chromosome region 18q22-23. Diabetes (2004) 0.82
Tumor necrosis factor-alpha promotes tumor growth by inducing vascular endothelial growth factor. Cancer Invest (2011) 0.82
Integrin αIIb-mediated PI3K/Akt activation in platelets. PLoS One (2012) 0.82
Clinical analysis of the treatment of spinocerebellar ataxia and multiple system atrophy-cerebellar type with umbilical cord mesenchymal stromal cells. Cytotherapy (2011) 0.81
Investigation on fragmentation pathways of rutaecarpine and its two derivatives using electrospray ionization ion-trap time-of-flight tandem mass spectrometry. Rapid Commun Mass Spectrom (2010) 0.81
Expression and purification of His-tagged rat mitochondrial 3-ketoacyl-CoA thiolase wild-type and His352 mutant proteins. Protein Expr Purif (2004) 0.81
Detection of HBV genotypes of tumor tissues and serum by a fluorescence polarization assay in north-western China's hepatocellular carcinoma patients. Virol J (2011) 0.81
Studies of human mitochondrial 2,4-dienoyl-CoA reductase. Arch Biochem Biophys (2005) 0.80
Fabrication and photoelectrochemical property of tungsten(vi) oxide films with a flake-wall structure. Chem Commun (Camb) (2010) 0.80
Personal exposure level and environmental ethylene oxide gas concentration in sterilization facilities of hospitals in Japan. Appl Occup Environ Hyg (2002) 0.80
Inhibition of mevalonate 5-diphosphate decarboxylase by fluorinated substrate analogs. Biochim Biophys Acta (2006) 0.80
Impact of planarity of unfused aromatic molecules on G-quadruplex binding: learning from isaindigotone derivatives. Org Biomol Chem (2011) 0.80
Selective recognition of oncogene promoter G-quadruplexes by Mg2+. Biochem Biophys Res Commun (2010) 0.80
Bifunctional inhibitors of mevalonate kinase and mevalonate 5-diphosphate decarboxylase. Org Lett (2006) 0.80
A human-derived protein SBP (HBsAg-binding protein) can bind to hepatitis B virus surface antigen (HBsAg) and enhance the immune response to hepatitis B virus (HBV) vaccine. Mol Immunol (2012) 0.79
Mechanistic studies for the role of cellular nucleic-acid-binding protein (CNBP) in regulation of c-myc transcription. Biochim Biophys Acta (2013) 0.79
Clueless regulates aPKC activity and promotes self-renewal cell fate in Drosophila lgl mutant larval brains. Dev Biol (2013) 0.79
Screening of an antigen target for immunocontraceptives from cross-reactive antigens between human sperm and Ureaplasma urealyticum. Infect Immun (2007) 0.79
Spatial and temporal expression of c-mos in mouse testis during postnatal development. Asian J Androl (2007) 0.78
Structural and biochemical characterization of fructose-1,6/sedoheptulose-1,7-bisphosphatase from the cyanobacterium Synechocystis strain 6803. FEBS J (2013) 0.78
Expression and purification of His-tagged rat mitochondrial medium-chain acyl-CoA dehydrogenase wild-type and Arg256 mutant proteins. Protein Expr Purif (2004) 0.78
Structure-based rational screening of novel hit compounds with structural diversity for cytochrome P450 sterol 14alpha-demethylase from Penicillium digitatum. J Chem Inf Model (2010) 0.78
The role of positive charges on G-quadruplex binding small molecules: learning from bisaryldiketene derivatives. Biochim Biophys Acta (2013) 0.78
Inactivation of thiolase by 2-alkynoyl-CoA via its intrinsic isomerase activity. Org Lett (2007) 0.78
True complete left bundle branch block morphology strongly predicts good response to cardiac resynchronization therapy. Europace (2013) 0.78
Design, synthesis and biological evaluation of novel mansonone E derivatives prepared via CuAAC click chemistry as topoisomerase II inhibitors. Eur J Med Chem (2013) 0.78
Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA. Eur J Med Chem (2011) 0.78
Expression, purification, and characterization of His20 mutants of rat mevalonate kinase. Protein Expr Purif (2003) 0.78
Mechanistic studies for tri-targeted inhibition of enzymes involved in cholesterol biosynthesis by green tea polyphenols. Org Biomol Chem (2014) 0.78
G-Quadruplex conformational change driven by pH variation with potential application as a nanoswitch. Biochim Biophys Acta (2013) 0.78
Development of a universal colorimetric indicator for G-quadruplex structures by the fusion of thiazole orange and isaindigotone skeleton. Anal Chem (2012) 0.78
Expression and purification of Arg196 and Lys272 mutants of mevalonate kinase from Methanococcus jannaschii. Protein Expr Purif (2003) 0.78
Functional studies of rat galactokinase. J Biotechnol (2009) 0.78
Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II. Org Biomol Chem (2013) 0.78
Effect of a disulfide bond on mevalonate kinase. Biochim Biophys Acta (2007) 0.77
Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation. Bioorg Med Chem (2012) 0.77
Probing the active site of rat porphobilinogen synthase using newly developed inhibitors. Bioorg Chem (2008) 0.77
Syntheses and characterization of novel oxoisoaporphine derivatives as dual inhibitors for cholinesterases and amyloid beta aggregation. Eur J Med Chem (2011) 0.77
Discovery of potent inhibitor for farnesyl pyrophosphate synthase in the mevalonate pathway. Chem Commun (Camb) (2010) 0.77
Construction and characterization of a CTLA-4-targeted scFv-melittin fusion protein as a potential immunosuppressive agent for organ transplant. Cell Biochem Biophys (2013) 0.77
Detection of H. pylori antibody profile in serum by protein array. World J Gastroenterol (2006) 0.77
Oct-2-yn-4-enoyl-CoA as a multifunctional enzyme inhibitor in fatty acid oxidation. Org Lett (2008) 0.77
Interaction of Berberine derivative with protein POT1 affect telomere function in cancer cells. Biochem Biophys Res Commun (2012) 0.77
Conversion of natively unstructured α-synuclein to its α-helical conformation significantly attenuates production of reactive oxygen species. J Inorg Biochem (2012) 0.77
Downregulation of Col1a1 induces differentiation in mouse spermatogonia. Asian J Androl (2012) 0.77
Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids. Chem Commun (Camb) (2014) 0.77
Oct-2-en-4-ynoyl-CoA as a specific inhibitor of acyl-CoA oxidase. Org Lett (2008) 0.77
New quinazoline derivatives for telomeric G-quadruplex DNA: effects of an added phenyl group on quadruplex binding ability. Eur J Med Chem (2013) 0.77
Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation. Bioorg Med Chem (2010) 0.77
3D-QSAR studies of azaoxoisoaporphine, oxoaporphine, and oxoisoaporphine derivatives as anti-AChE and anti-AD agents by the CoMFA method. J Mol Graph Model (2013) 0.77
Effective detection and separation method for G-quadruplex DNA based on its specific precipitation with Mg(2+). Biomacromolecules (2010) 0.76
Syntheses and evaluation of novel isoliquiritigenin derivatives as potential dual inhibitors for amyloid-beta aggregation and 5-lipoxygenase. Eur J Med Chem (2013) 0.76
New insights into the structures of ligand-quadruplex complexes from molecular dynamics simulations. J Phys Chem B (2010) 0.76
Inscuteable-independent apicobasally oriented asymmetric divisions in the Drosophila embryonic CNS. EMBO Rep (2002) 0.76
Expression, purification, and characterization of His-tagged human mitochondrial 2,4-dienoyl-CoA reductase. Protein Expr Purif (2003) 0.76
Combination of simvastatin and imatinib sensitizes the CD34+ cells in K562 to cell death. Med Oncol (2010) 0.76
Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents. Eur J Med Chem (2011) 0.76