CTLA-4: a key regulatory point in the control of autoimmune disease.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMID 18613834)

Published in Immunol Rev on June 01, 2008

Authors

Kenneth J Scalapino1, David I Daikh

Author Affiliations

1: Department of Medicine, Division of Rheumatology, University of California, San Francisco, San Francisco, CA 94121, USA.

Articles citing this

Human T regulatory cell therapy: take a billion or so and call me in the morning. Immunity (2009) 3.21

Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family. Immunol Rev (2011) 2.54

CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms. Nat Immunol (2009) 1.70

Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression. J Immunol (2012) 1.30

Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity. J Exp Med (2015) 1.01

Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade. J Clin Invest (2015) 0.98

Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family. Immunity (2016) 0.96

CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire. Proc Natl Acad Sci U S A (2012) 0.95

CD28 expression is required after T cell priming for helper T cell responses and protective immunity to infection. Elife (2014) 0.94

The B7-independent isoform of CTLA-4 functions to regulate autoimmune diabetes. J Immunol (2013) 0.93

Current and future immunomodulation strategies to restore tolerance in autoimmune diseases. Cold Spring Harb Perspect Biol (2012) 0.91

cAMP-responsive element modulator α (CREMα) contributes to decreased Notch-1 expression in T cells from patients with active systemic lupus erythematosus (SLE). J Biol Chem (2012) 0.91

Genome-Wide Association Studies in Primary Biliary Cirrhosis. Semin Liver Dis (2015) 0.90

Advances in the current treatment of autoimmune hepatitis. Dig Dis Sci (2012) 0.89

Coinhibitory molecules in autoimmune diseases. Clin Dev Immunol (2012) 0.88

Activation-induced accumulation of B and T lymphocyte attenuator at the immunological synapse in CD4+ T cells. J Leukoc Biol (2009) 0.86

The genetic basis of primary biliary cirrhosis: premises, not promises. Gastroenterology (2008) 0.85

Stereotactic radiation therapy combined with immunotherapy: augmenting the role of radiation in local and systemic treatment. Oncology (Williston Park) (2015) 0.85

Acquired hemophilia A: a frequently overlooked autoimmune hemorrhagic disorder. J Immunol Res (2014) 0.84

Association between co-inhibitory molecule gene tagging single nucleotide polymorphisms and the risk of colorectal cancer in Chinese. J Cancer Res Clin Oncol (2015) 0.83

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells. PLoS Genet (2017) 0.82

Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. Proc Natl Acad Sci U S A (2015) 0.82

Role of adaptive immunity in alcoholic liver disease. Int J Hepatol (2011) 0.81

Impact of microbes on autoimmune diseases. Arch Immunol Ther Exp (Warsz) (2013) 0.80

Implications of genome-wide association studies in novel therapeutics in primary biliary cirrhosis. Eur J Immunol (2014) 0.80

Association of genetic polymorphisms with osteosarcoma risk: a meta-analysis. Int J Clin Exp Med (2015) 0.79

The availability of a functional tumor targeting T-cell repertoire determines the anti-tumor efficiency of combination therapy with anti-CTLA-4 and anti-4-1BB antibodies. PLoS One (2013) 0.79

Genetic and epigenetic variation in the lineage specification of regulatory T cells. Elife (2015) 0.78

Emerging opportunities for site-specific molecular and cellular interventions in autoimmune hepatitis. Dig Dis Sci (2010) 0.78

Regulatory T cell in stroke: a new paradigm for immune regulation. Clin Dev Immunol (2013) 0.78

Diagnosis and Management of Autoimmune Hepatitis: Current Status and Future Directions. Gut Liver (2016) 0.77

Molecular insights for optimizing T cell receptor specificity against cancer. Front Immunol (2013) 0.77

The expanding role of immunopharmacology: IUPHAR Review 16. Br J Pharmacol (2015) 0.77

CTLA-4 polymorphisms and systemic lupus erythematosus: a comprehensive meta-analysis. Genet Test Mol Biomarkers (2013) 0.77

Local immunomodulation for cancer therapy: Providing treatment where needed. Oncoimmunology (2013) 0.77

Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them? J Immunol (2016) 0.76

CYP2E1 autoantibodies in liver diseases. Redox Biol (2014) 0.76

Cytotoxic T lymphocyte-associated antigen 4 gene polymorphisms and autoimmune thyroid diseases: an updated systematic review and cumulative meta-analysis. Int J Endocrinol (2015) 0.76

Autoimmune hepatitis in childhood: the role of genetic and immune factors. World J Gastroenterol (2013) 0.76

CTLA4CT60 gene polymorphism is not associated with differential susceptibility to pemphigus foliaceus. Genet Mol Biol (2010) 0.76

Prostate cancer immunotherapy, particularly in combination with androgen deprivation or radiation treatment. Customized pharmacogenomic approaches to overcome immunotherapy cancer resistance. G Chir (2017) 0.75

Antigen-specific regulatory T-cell responses to intestinal microbiota. Mucosal Immunol (2017) 0.75

Articles by these authors

American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis. Arthritis Care Res (Hoboken) (2012) 6.51

Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease? Am J Respir Crit Care Med (2007) 2.69

Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cells. J Immunol (2006) 1.75

An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus. Arthritis Rheum (2008) 1.44

Randomised double blind trial of etoricoxib and indometacin in treatment of acute gouty arthritis. BMJ (2002) 1.37

Accelerated nodulosis and vasculitis following etanercept therapy for rheumatoid arthritis. Arthritis Rheum (2002) 1.11

Suppression of glomerulonephritis in NZB/NZW lupus prone mice by adoptive transfer of ex vivo expanded regulatory T cells. PLoS One (2009) 1.03

Prevention of renal damage in murine lupus nephritis by CTLA-4Ig and cyclophosphamide. Arthritis Rheum (2004) 0.89

Updated recommendations for the treatment of rheumatoid arthritis: another step on a long road. Arthritis Care Res (Hoboken) (2012) 0.85

B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency. J Exp Med (2008) 0.84

Novel model of antigen-specific induction of bile duct injury. Gastroenterology (2006) 0.84

Resolution of recurrent fusarium arthritis after prolonged antifungal therapy. J Clin Rheumatol (2011) 0.78

Identification of risk factors for elevated transaminases in methotrexate users through an electronic health record. Arthritis Care Res (Hoboken) (2014) 0.78

The Vioxx debacle revisited. Am J Med (2005) 0.75

Rheumatic manifestations of cancer. Rheum Dis Clin North Am (2011) 0.75