Published in Genes Immun on July 24, 2008
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet (2009) 7.16
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet (2009) 4.97
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet (2008) 3.93
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet (2009) 3.52
Recent advances in the genetics of autoimmune disease. Annu Rev Immunol (2009) 2.41
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. Eur J Hum Genet (2009) 1.97
Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Am J Hum Genet (2010) 1.89
Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci. Hum Mol Genet (2009) 1.80
A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis. PLoS One (2010) 1.38
The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression. PLoS One (2010) 1.18
The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation. J Cell Biol (2010) 1.13
A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility. Genes Immun (2011) 1.08
CD6 synergistic co-stimulation promoting proinflammatory response is modulated without interfering with the activated leucocyte cell adhesion molecule interaction. Clin Exp Immunol (2010) 1.04
CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis. Hum Mol Genet (2010) 1.01
A transcription factor map as revealed by a genome-wide gene expression analysis of whole-blood mRNA transcriptome in multiple sclerosis. PLoS One (2010) 1.00
A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis. Ann Rheum Dis (2009) 0.99
Refining the association of MHC with multiple sclerosis in African Americans. Hum Mol Genet (2010) 0.96
Type 1 diabetes mellitus and multiple sclerosis: common etiological features. Nat Rev Endocrinol (2009) 0.95
Revealing the genetic basis of multiple sclerosis: are we there yet? Curr Opin Genet Dev (2011) 0.93
Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals. Hum Mol Genet (2010) 0.93
Variation within DNA repair pathway genes and risk of multiple sclerosis. Am J Epidemiol (2010) 0.93
Sequencing and analysis of a South Asian-Indian personal genome. BMC Genomics (2012) 0.91
Association study of ITGAM, ITGAX, and CD58 autoimmune risk loci in systemic sclerosis: results from 2 large European Caucasian cohorts. J Rheumatol (2011) 0.89
Alternative splicing and transcriptome profiling of experimental autoimmune encephalomyelitis using genome-wide exon arrays. PLoS One (2009) 0.88
Tag-SNP analysis of the GFI1-EVI5-RPL5-FAM69 risk locus for multiple sclerosis. Eur J Hum Genet (2010) 0.87
Polymorphisms in the inflammatory genes CIITA, CLEC16A and IFNG influence BMD, bone loss and fracture in elderly women. PLoS One (2012) 0.87
Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility. PLoS One (2011) 0.86
Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients. PLoS One (2010) 0.85
From Identification to Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A. Int J Mol Sci (2013) 0.84
Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat. PLoS One (2010) 0.82
Multiple linked quantitative trait loci within the Tmevd2/Eae3 interval control the severity of experimental allergic encephalomyelitis in DBA/2J mice. Genes Immun (2010) 0.81
HLA class II alleles in patients with multiple sclerosis in the Biscay province (Basque Country, Spain). J Neurol (2009) 0.80
CD6 gene polymorphism rs17824933 is associated with multiple sclerosis in Indian population. Ann Indian Acad Neurol (2016) 0.78
Autoimmune T-cell reactivity to myelin proteolipids and glycolipids in multiple sclerosis. Mult Scler Int (2013) 0.78
Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis. Eur J Hum Genet (2011) 0.78
Association between the IL7R T244I polymorphism and multiple sclerosis risk: a meta analysis. Neurol Sci (2016) 0.77
Gut commensalism, cytokines, and central nervous system demyelination. J Interferon Cytokine Res (2014) 0.77
Replication study of multiple sclerosis (MS) susceptibility alleles and correlation of DNA-variants with disease features in a cohort of Austrian MS patients. Neurogenetics (2012) 0.76
Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. Genes Immun (2009) 0.76
Association of EVI5 rs11808092, CD58 rs2300747, and CIITA rs3087456 polymorphisms with multiple sclerosis risk: A meta-analysis. Meta Gene (2016) 0.75
Association of CD58 Polymorphism with Multiple Sclerosis and Response to Interferon ß Therapy in A Subset of Iranian Population. Cell J (2015) 0.75
Where is the causal variant? On the advantage of the family design over the case-control design in genetic association studies. Eur J Hum Genet (2015) 0.75
CD58 polymorphisms associated with the risk of neuromyelitis optica in a Korean population. BMC Neurol (2014) 0.75
Systemic Lupus Erythematosus Patients Exhibit Reduced Expression of CLEC16A Isoforms in Peripheral Leukocytes. Int J Mol Sci (2015) 0.75
A candidate gene study of CLEC16A does not provide evidence of association with risk for anti-CCP-positive rheumatoid arthritis. Genes Immun (2010) 0.75
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89
General practitioner's perceptions of the route to evidence based medicine: a questionnaire survey. BMJ (1998) 13.39
Sexual behaviour in Britain: partnerships, practices, and HIV risk behaviours. Lancet (2001) 13.31
Sexual behaviour in Britain: reported sexually transmitted infections and prevalent genital Chlamydia trachomatis infection. Lancet (2001) 9.75
Sexual lifestyles and HIV risk. Nature (1992) 8.24
Sexual behaviour in Britain: early heterosexual experience. Lancet (2001) 7.62
Microarray expression profiling identifies genes with altered expression in HDL-deficient mice. Genome Res (2000) 4.95
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. Proc Natl Acad Sci U S A (1988) 4.58
Origins of agriculture at Kuk Swamp in the highlands of New Guinea. Science (2003) 4.45
The pathogenesis of hemorrhagic colitis caused by Escherichia coli O157:H7 in gnotobiotic piglets. J Infect Dis (1986) 3.96
Phylogenetic analysis of enterovirus 71 strains isolated during linked epidemics in Malaysia, Singapore, and Western Australia. J Virol (2001) 3.80
Identification of a novel aspartic protease (Asp 2) as beta-secretase. Mol Cell Neurosci (1999) 3.77
Estimation and assessment of raw copy numbers at the single locus level. Bioinformatics (2008) 3.62
RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor. Cell (1986) 3.57
Modeling interference in genetic recombination. Genetics (1995) 3.47
Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity. Neurology (2005) 3.45
Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes. Lancet (1993) 3.38
Isolation of subgenus B adenovirus during a fatal outbreak of enterovirus 71-associated hand, foot, and mouth disease in Sibu, Sarawak. Lancet (1999) 3.21
Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1986) 3.19
Sexual lifestyles under scrutiny. Nature (1990) 3.19
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest (2000) 3.17
Computer support for interpreting family histories of breast and ovarian cancer in primary care: comparative study with simulated cases. BMJ (2000) 3.12
Statistical analysis of crossover interference using the chi-square model. Genetics (1995) 3.06
Effect of computer-assisted self-interviews on reporting of sexual HIV risk behaviours in a general population sample: a methodological experiment. AIDS (2001) 3.03
Who goes to sexually transmitted disease clinics? Results from a national population survey. Genitourin Med (1996) 3.02
T cells in multiple sclerosis and experimental autoimmune encephalomyelitis. Clin Exp Immunol (2010) 2.94
Separation of the adenovirus terminal protein precursor from its associated DNA polymerase: role of both proteins in the initiation of adenovirus DNA replication. Proc Natl Acad Sci U S A (1982) 2.65
Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele. Nat Genet (2001) 2.54
FIRMA: a method for detection of alternative splicing from exon array data. Bioinformatics (2008) 2.49
Over- and underrepresentation of short DNA words in herpesvirus genomes. J Comput Biol (1996) 2.48
Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.45
Retracted Mutations at more than one locus may be involved in cystic fibrosis--evidence based on first-cousin data and direct counting of cases. Am J Hum Genet (1983) 2.45
A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis. Neurology (2011) 2.39
Changes in weight, fluid balance and serum albumin in patients referred for nutritional support. Clin Nutr (1999) 2.28
Identification and analysis of error types in high-throughput genotyping. Am J Hum Genet (2000) 2.23
Provision of sex education and early sexual experience: the relation examined. BMJ (1995) 2.21
Colorimetric detection of specific DNA segments amplified by polymerase chain reactions. Proc Natl Acad Sci U S A (1989) 2.14
Past exposure to sun, skin phenotype, and risk of multiple sclerosis: case-control study. BMJ (2003) 2.12
Interactive effect of Gm allotypes and HLA-B locus antigens on the human antibody response to a bacterial antigen. Clin Exp Immunol (1980) 2.12
Audit of outcome of long-term enteral nutrition by percutaneous endoscopic gastrostomy. Lancet (1993) 2.10
Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum. EMBO J (1992) 2.09
Combined chemotherapy with ABCM versus melphalan for treatment of myelomatosis. The Medical Research Council Working Party for Leukaemia in Adults. Lancet (1992) 2.08
Umbilical cord blood banks in the UK. BMJ (2001) 2.08
Evidence for a functional link between profilin and CAP in the yeast S. cerevisiae. Cell (1991) 2.05
Sun exposure and vitamin D are independent risk factors for CNS demyelination. Neurology (2011) 2.04
Raised levels of calcium-binding protein in plasma following insulin-induced hypoglycaemia in the pig. J Endocrinol (1986) 2.03
Remission of diarrhoea due to cryptosporidiosis in an immunodeficient child treated with hyperimmune bovine colostrum. Br Med J (Clin Res Ed) (1986) 2.00
CAP is a bifunctional component of the Saccharomyces cerevisiae adenylyl cyclase complex. Mol Cell Biol (1991) 1.98
De novo generation of neuronal cells from the adult mouse brain. Proc Natl Acad Sci U S A (1992) 1.97
Gait and balance impairment in early multiple sclerosis in the absence of clinical disability. Mult Scler (2006) 1.95
Methodology of the National Survey of Sexual Attitudes and Lifestyles. J R Stat Soc Ser A Stat Soc (1993) 1.95
Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts. Mol Cell Biol (1997) 1.94
Structure of the RESA gene of Plasmodium falciparum. Nucleic Acids Res (1986) 1.92
Vitamin D levels in people with multiple sclerosis and community controls in Tasmania, Australia. J Neurol (2007) 1.92
A comparison of topical acyclovir with steroids in the treatment of herpes zoster keratouveitis. Br J Ophthalmol (1983) 1.91
'Neurophobia'--attitudes of medical students and doctors in Ireland to neurological teaching. Eur J Neurol (2007) 1.91
Impact of the "physician factor" on pregnancy rates in a large assisted reproductive technology program: do too many cooks spoil the broth? Fertil Steril (1999) 1.88
Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent events. Mol Cell Biol (1991) 1.85
An actin monomer binding activity localizes to the carboxyl-terminal half of the Saccharomyces cerevisiae cyclase-associated protein. J Biol Chem (1995) 1.83
A conserved proline-rich region of the Saccharomyces cerevisiae cyclase-associated protein binds SH3 domains and modulates cytoskeletal localization. Mol Cell Biol (1996) 1.82
Statistical analysis of chromatid interference. Genetics (1995) 1.80
The adenylyl cyclase gene from Schizosaccharomyces pombe. Proc Natl Acad Sci U S A (1989) 1.73
Experimental design and low-level analysis of microarray data. Int Rev Neurobiol (2004) 1.73
Helping effort and future fitness in cooperation animal societies. Proc Biol Sci (2001) 1.71
Mapping the prevalence of sickle cell and beta thalassaemia in England: estimating and validating ethnic-specific rates. Br J Haematol (1999) 1.67
Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes. Diabetes (2000) 1.67
GFI1B mutation causes a bleeding disorder with abnormal platelet function. J Thromb Haemost (2013) 1.66
HLA associations with autoimmune-type chronic active hepatitis: identification of B8-DRw3 haplotype by family studies. Gastroenterology (1980) 1.65
On genetic map functions. Genetics (1996) 1.64
Application of the three-dimensional structures of protein target molecules in structure-based drug design. J Med Chem (1994) 1.61
Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lung. J Appl Physiol (1985) (1995) 1.61
A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK. Science (2001) 1.61
Analysis of cDNA microarray images. Brief Bioinform (2001) 1.60
Isolation of proteins involved in the replication of adenoviral DNA in vitro. Cold Spring Harb Symp Quant Biol (1983) 1.60
Double-blind comparison of addition of a second mood stabilizer versus an antidepressant to an initial mood stabilizer for treatment of patients with bipolar depression. Am J Psychiatry (2000) 1.57
Purification of a primase activity associated with DNA polymerase alpha from HeLa cells. J Biol Chem (1984) 1.56
Neurological symptoms 27 years after tiger bite. J R Soc Med (1999) 1.54
The in vitro replication of adenovirus DNA. Curr Top Microbiol Immunol (1984) 1.53
Are Melnick-Needles syndrome and oto-palato-digital syndrome type II allelic? Observations in a four-generation kindred. Am J Med Genet (1997) 1.53
Factors associated with human immunodeficiency virus seroconversion in homosexual men in three San Francisco cohort studies, 1984-1989. J Acquir Immune Defic Syndr (1993) 1.53
The Akt proto-oncogene links Ras to Pak and cell survival signals. J Biol Chem (2000) 1.53
Multiple sclerosis prevalence in Ireland: relationship to vitamin D status and HLA genotype. J Neurol Neurosurg Psychiatry (2011) 1.52
Measurement of plasma digoxin concentration by radioimmunoassay. Br Med J (1970) 1.51
Properties of the adenovirus DNA polymerase. J Biol Chem (1984) 1.51
Phat--a gene finding program for Plasmodium falciparum. Mol Biochem Parasitol (2001) 1.49
A randomised controlled trial: outcomes of bladder rehabilitation in persons with multiple sclerosis. J Neurol Neurosurg Psychiatry (2010) 1.48
Studies of RAS function in the yeast Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol (1988) 1.48
A proposed modification to the McDonald 2010 criteria for the diagnosis of primary progressive multiple sclerosis. Mult Scler (2012) 1.47
An estimate of the crosstalk matrix in four-dye fluorescence-based DNA sequencing. Electrophoresis (1999) 1.47
Problems of urgent consultations within an appointment system. J R Coll Gen Pract (1980) 1.45