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Lipidomics reveals a remarkable diversity of lipids in human plasma.
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J Lipid Res
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2010
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2
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SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder.
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Cell
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2010
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2.49
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3
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A mouse macrophage lipidome.
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J Biol Chem
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2010
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2.14
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4
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Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP.
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Nat Struct Mol Biol
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2005
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2.03
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5
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Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis.
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Cell Metab
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2011
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1.97
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6
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A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacin.
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Biochemistry
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2005
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1.86
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7
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Different routes to the same ending: comparing the N-glycosylation processes of Haloferax volcanii and Haloarcula marismortui, two halophilic archaea from the Dead Sea.
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Mol Microbiol
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2011
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1.72
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Attenuated virulence of a Francisella mutant lacking the lipid A 4'-phosphatase.
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Proc Natl Acad Sci U S A
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2007
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1.64
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Discovery of new biosynthetic pathways: the lipid A story.
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J Lipid Res
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2008
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Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1.
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Proc Natl Acad Sci U S A
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2005
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1.49
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11
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Structure and biosynthesis of free lipid A molecules that replace lipopolysaccharide in Francisella tularensis subsp. novicida.
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Biochemistry
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2006
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1.47
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12
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Subcellular organelle lipidomics in TLR-4-activated macrophages.
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J Lipid Res
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2010
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13
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The active conformation of beta-arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of beta-arrestins1 and -2.
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J Biol Chem
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2007
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14
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AglJ adds the first sugar of the N-linked pentasaccharide decorating the Haloferax volcanii S-layer glycoprotein.
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J Bacteriol
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2010
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1.38
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15
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Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates.
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Proc Natl Acad Sci U S A
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2012
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1.29
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16
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Electron capture dissociation mass spectrometry in characterization of peptides and proteins.
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2006
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Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content.
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PLoS One
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2012
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1.23
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18
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Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway.
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Biochemistry
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2005
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1.21
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19
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Cardiolipin and the osmotic stress responses of bacteria.
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Biochim Biophys Acta
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2009
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An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli.
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J Biol Chem
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2007
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21
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Plasticity of lipid-protein interactions in the function and topogenesis of the membrane protein lactose permease from Escherichia coli.
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Proc Natl Acad Sci U S A
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2010
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1.17
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The lipid lysyl-phosphatidylglycerol is present in membranes of Rhizobium tropici CIAT899 and confers increased resistance to polymyxin B under acidic growth conditions.
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Mol Plant Microbe Interact
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2007
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1.16
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Purification and mutagenesis of LpxL, the lauroyltransferase of Escherichia coli lipid A biosynthesis.
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Biochemistry
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2008
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24
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Identification of self-lipids presented by CD1c and CD1d proteins.
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J Biol Chem
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2011
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25
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Sinorhizobium meliloti phospholipase C required for lipid remodeling during phosphorus limitation.
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Proc Natl Acad Sci U S A
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2009
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1.11
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26
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Two distinct N-glycosylation pathways process the Haloferax volcanii S-layer glycoprotein upon changes in environmental salinity.
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MBio
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2013
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1.10
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27
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Analysis of ubiquinones, dolichols, and dolichol diphosphate-oligosaccharides by liquid chromatography-electrospray ionization-mass spectrometry.
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Methods Enzymol
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2007
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28
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Three phosphatidylglycerol-phosphate phosphatases in the inner membrane of Escherichia coli.
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J Biol Chem
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2010
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29
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Remodelling of the Vibrio cholerae membrane by incorporation of exogenous fatty acids from host and aquatic environments.
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Mol Microbiol
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2010
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30
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An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A.
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Biochemistry
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2008
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31
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A phosphoethanolamine-modified glycosyl diradylglycerol in the polar lipids of Clostridium tetani.
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J Lipid Res
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32
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Identification of undecaprenyl phosphate-beta-D-galactosamine in Francisella novicida and its function in lipid A modification.
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Biochemistry
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2009
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1.01
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33
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Expression cloning of three Rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases.
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J Biol Chem
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2006
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Glyco-engineering in Archaea: differential N-glycosylation of the S-layer glycoprotein in a transformed Haloferax volcanii strain.
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2011
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Application of proteomic marker ensembles to subcellular organelle identification.
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Mol Cell Proteomics
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2009
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AglR is required for addition of the final mannose residue of the N-linked glycan decorating the Haloferax volcanii S-layer glycoprotein.
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2012
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Platensimycin and platencin congeners from Streptomyces platensis.
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2011
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Isolation and structure of antagonists of chemokine receptor (CCR5).
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Hydroxylated ornithine lipids increase stress tolerance in Rhizobium tropici CIAT899.
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Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8.
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Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.
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Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites.
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2004
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A eukaryote-like cardiolipin synthase is present in Streptomyces coelicolor and in most actinobacteria.
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Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources.
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Biosynthesis of undecaprenyl phosphate-galactosamine and undecaprenyl phosphate-glucose in Francisella novicida.
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Biochemistry
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Durhamycin A, a potent inhibitor of HIV Tat transactivation.
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Role of unusual P loop ejection and autophosphorylation in HipA-mediated persistence and multidrug tolerance.
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Discovery of a bifunctional acyltransferase responsible for ornithine lipid synthesis in Serratia proteamaculans.
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Environ Microbiol
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Substrate promiscuity: AglB, the archaeal oligosaccharyltransferase, can process a variety of lipid-linked glycans.
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Appl Environ Microbiol
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Electron capture dissociation mass spectrometry in characterization of post-translational modifications.
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Biochem Biophys Res Commun
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Molecular characterization of the cis-prenyltransferase of Giardia lamblia.
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Glycobiology
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Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis.
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J Biol Chem
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Expression of functional bacterial undecaprenyl pyrophosphate synthase in the yeast rer2{Delta} mutant and CHO cells.
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Glycobiology
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Identification and quantification of dolichol and dolichoic acid in neuromelanin from substantia nigra of the human brain.
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J Lipid Res
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2007
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The outer surface lipoprotein VolA mediates utilization of exogenous lipids by Vibrio cholerae.
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Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli.
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Proc Natl Acad Sci U S A
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Diversity in prokaryotic glycosylation: an archaeal-derived N-linked glycan contains legionaminic acid.
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Highly substituted terphenyls as inhibitors of parasite cGMP-dependent protein kinase activity.
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Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3.
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Isolation and structures of novel fungal metabolites as chemokine receptor (CCR2) antagonists.
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Modification of cysteine 111 in human Cu,Zn-superoxide dismutase.
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Anthrabenzoxocinones from Streptomyces sp. as liver X receptor ligands and antibacterial agents.
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Aberrant dolichol chain lengths as biomarkers for retinitis pigmentosa caused by impaired dolichol biosynthesis.
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Agrobacteria lacking ornithine lipids induce more rapid tumour formation.
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Lipid modification gives rise to two distinct Haloferax volcanii S-layer glycoprotein populations.
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Tenellones A and B from a Diaporthe sp.: two highly substituted benzophenone inhibitors of parasite cGMP-dependent protein kinase activity.
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An ethanolamine-phosphate modified glycolipid in Clostridium acetobutylicum that responds to membrane stress.
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AglQ is a novel component of the Haloferax volcanii N-glycosylation pathway.
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Dolichyl-phosphate-glucose is used to make O-glycans on glycoproteins of Trichomonas vaginalis.
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Eukaryot Cell
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Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis.
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Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC.
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A predicted geranylgeranyl reductase reduces the ω-position isoprene of dolichol phosphate in the halophilic archaeon, Haloferax volcanii.
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Distinct granuloma responses in C57BL/6J and BALB/cByJ mice in response to pristane.
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Probing conformational changes in human DNA topoisomerase IIα by pulsed alkylation mass spectrometry.
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Isolation, structure, absolute stereochemistry, and HIV-1 integrase inhibitory activity of integrasone, a novel fungal polyketide.
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Phosphorylation analysis of G protein-coupled receptor by mass spectrometry: identification of a phosphorylation site in V2 vasopressin receptor.
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Isolation, structure, and HIV-1 integrase inhibitory activity of Cytosporic acid, a fungal metabolite produced by a Cytospora sp.
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Guttiferone I, a new prenylated benzophenone from Garcinia humilis as a liver X receptor ligand.
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Integramides A and B, two novel non-ribosomal linear peptides containing nine C(alpha)-methyl amino acids produced by fungal fermentations that are inhibitors of HIV-1 integrase.
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Negative control of mast cell degranulation and the anaphylactic response by the phosphatase lipin1.
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The unanticipated loss of SO2 from sulfonamides in collision-induced dissociation.
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Characterization of the Vibrio cholerae VolA surface-exposed lipoprotein lysophospholipase.
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Isolation and insecticidal/anthelmintic activity of xanthonol, a novel bis-xanthone, from a non-sporulating fungal species.
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