Published in Eur J Cancer on August 06, 2008
Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis. Blood (2010) 1.61
Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis. J Exp Med (2010) 1.48
Correlation of vascular endothelial growth factor expression with tumor recurrence and poor prognosis in patients with pN0 gastric cancer. World J Surg (2012) 1.41
The tumor microenvironment in colorectal carcinogenesis. Cancer Microenviron (2010) 1.23
Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth. Proc Natl Acad Sci U S A (2011) 1.20
The role of chemokines in intestinal inflammation and cancer. Curr Opin Pharmacol (2009) 1.16
Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature. Matrix Biol (2015) 1.15
The role of stromal myofibroblast and extracellular matrix in tumor angiogenesis. Genes Cancer (2011) 1.14
Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis. Development (2011) 1.13
Gelatinase B/MMP-9 in Tumour Pathogenesis and Progression. Cancers (Basel) (2014) 1.10
The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer. J Transl Med (2012) 1.08
Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor. J Immunol (2011) 1.07
H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo. Mol Cancer Res (2009) 1.06
The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF. Biomaterials (2009) 1.05
Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning. Cytokine Growth Factor Rev (2013) 1.05
Identification of TNF-alpha and MMP-9 as potential baseline predictive serum markers of sunitinib activity in patients with renal cell carcinoma using a human cytokine array. Br J Cancer (2009) 1.04
Glucose and inflammation control islet vascular density and beta-cell function in NOD mice: control of islet vasculature and vascular endothelial growth factor by glucose. Diabetes (2011) 0.98
Extracellular matrix proteins and tumor angiogenesis. J Oncol (2010) 0.97
Neutrophil granulocyte derived MMP-9 is a VEGF independent functional component of the angiogenic switch in pancreatic ductal adenocarcinoma. Angiogenesis (2011) 0.96
Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer. Carcinogenesis (2014) 0.94
Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis. BMC Syst Biol (2011) 0.94
Mesenchymal stem cells overexpressing CXCR4 attenuate remodeling of postmyocardial infarction by releasing matrix metalloproteinase-9. Stem Cells Dev (2011) 0.92
ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis. EMBO Mol Med (2013) 0.92
Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model. PLoS One (2010) 0.92
Pericellular proteolysis in cancer. Genes Dev (2014) 0.92
Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer. PLoS One (2015) 0.90
Neutrophils in Cancer: Two Sides of the Same Coin. J Immunol Res (2015) 0.90
MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients. Br J Cancer (2012) 0.88
Relationship between vitreous levels of matrix metalloproteinases and vascular endothelial growth factor in proliferative diabetic retinopathy. PLoS One (2013) 0.88
TIMP-2 targets tumor-associated myeloid suppressor cells with effects in cancer immune dysfunction and angiogenesis. J Immunother (2012) 0.86
Angiogenic markers endoglin and vascular endothelial growth factor in gastroenteropancreatic neuroendocrine tumors. World J Gastroenterol (2011) 0.85
Sesamin inhibits macrophage-induced vascular endothelial growth factor and matrix metalloproteinase-9 expression and proangiogenic activity in breast cancer cells. Inflammation (2011) 0.85
Extracellular molecules involved in cancer cell invasion. Cancers (Basel) (2015) 0.85
Detection of circulating vascular endothelial growth factor and matrix metalloproteinase-9 in non-small cell lung cancer using Luminex multiplex technology. Oncol Lett (2013) 0.85
Single-nucleotide polymorphisms of matrix metalloproteinases and their inhibitors in gastrointestinal cancer. World J Gastrointest Oncol (2011) 0.84
A cell-based model of extracellular-matrix-guided endothelial cell migration during angiogenesis. Bull Math Biol (2013) 0.84
WT1 regulates angiogenesis in Ewing Sarcoma. Oncotarget (2014) 0.82
Vaccinia virus-mediated intra-tumoral expression of matrix metalloproteinase 9 enhances oncolysis of PC-3 xenograft tumors. BMC Cancer (2012) 0.81
Tumor necrosis factor improves vascularization in osteogenic grafts engineered with human adipose-derived stem/stromal cells. PLoS One (2014) 0.81
Fibulin-4 deficiency increases TGF-β signalling in aortic smooth muscle cells due to elevated TGF-β2 levels. Sci Rep (2015) 0.79
Coexpression of heparanase activity, cathepsin L, tissue factor, tissue factor pathway inhibitor, and MMP-9 in proliferative diabetic retinopathy. Mol Vis (2016) 0.79
Reduction of Adipose Tissue Mass by the Angiogenesis Inhibitor ALS-L1023 from Melissa officinalis. PLoS One (2015) 0.79
Matrix Metalloproteinase-1 and Matrix Metalloproteinase-9 in the Aqueous Humor of Diabetic Macular Edema Patients. PLoS One (2016) 0.78
Association of endothelin-1 and matrix metallopeptidase-9 with metabolic syndrome in middle-aged and older adults. Diabetol Metab Syndr (2015) 0.78
Steady states and dynamics of urokinase-mediated plasmin activation in silico and in vitro. Biophys J (2011) 0.78
Detection of serum VEGF and MMP-9 levels by Luminex multiplexed assays in patients with breast infiltrative ductal carcinoma. Exp Ther Med (2014) 0.78
Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease. PLoS One (2016) 0.77
Early VEGFR2 activation in response to flow is VEGF-dependent and mediated by MMP activity. Biochem Biophys Res Commun (2013) 0.76
Matrix metalloproteinases as breast cancer drivers and therapeutic targets. Front Biosci (Landmark Ed) (2015) 0.76
Endoglin targeting inhibits tumor angiogenesis and metastatic spread in breast cancer. Oncogene (2016) 0.76
Progression of choroidal metastasis of ovarian serous cystoadenocarcinoma after intravitreal bevacizumab treatment. Rare Tumors (2013) 0.75
Anthrax lethal toxin suppresses high glucose induced VEGF over secretion through a post-translational mechanism. Int J Ophthalmol (2015) 0.75
Autoantibodies against muscarinic receptors in breast cancer: their role in tumor angiogenesis. PLoS One (2013) 0.75
Neutrophil count and percentage: potential independent prognostic indicators for advanced cancer patients in a palliative care setting. Oncotarget (2017) 0.75
Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition. Nat Commun (2017) 0.75
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial. Gut (2011) 6.08
Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity (2007) 4.70
Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. Nat Cell Biol (2012) 3.50
Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2). Blood (2002) 3.38
Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study. Gut (2010) 3.09
A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease. Clin Gastroenterol Hepatol (2006) 2.45
Mannose binding lectin gene polymorphisms confer a major risk for severe infections after liver transplantation. Gastroenterology (2005) 2.30
Lectin complement pathway gene profile of donor and recipient determine the risk of bacterial infections after orthotopic liver transplantation. Hepatology (2010) 2.25
Development of the Crohn's disease digestive damage score, the Lémann score. Inflamm Bowel Dis (2010) 2.20
The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue. Genomics (2002) 2.20
Role of tumor necrosis factor-alpha and interleukin-10 gene polymorphisms in irritable bowel syndrome. Am J Gastroenterol (2005) 2.09
Syndecan recycling [corrected] is controlled by syntenin-PIP2 interaction and Arf6. Dev Cell (2005) 2.08
PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane. Mol Cell (2002) 2.04
Mammalian heparanase: what is the message? J Cell Mol Med (2007) 1.91
Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses. Arterioscler Thromb Vasc Biol (2006) 1.87
Syndecan captures, protects, and transmits HIV to T lymphocytes. Immunity (2003) 1.86
Quality of web-based information on inflammatory bowel diseases. Inflamm Bowel Dis (2009) 1.81
Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease. Hum Mol Genet (2010) 1.78
Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants. J Pathol (2003) 1.77
Setting a research agenda for progressive multiple sclerosis: the International Collaborative on Progressive MS. Mult Scler (2012) 1.75
Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells. J Virol (2006) 1.74
Critical appraisal of the current practice in murine TNBS-induced colitis. Inflamm Bowel Dis (2006) 1.71
Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel disease. Inflamm Bowel Dis (2007) 1.70
The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers. Gastroenterology (2008) 1.61
Origin and functional activity of the membrane-bound glucocorticoid receptor. Arthritis Rheum (2011) 1.59
Matrix metalloproteinase-14 (MT1-MMP)-mediated endoglin shedding inhibits tumor angiogenesis. Cancer Res (2010) 1.56
Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists. Mol Cell Endocrinol (2007) 1.55
Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1. Proc Natl Acad Sci U S A (2007) 1.54
Identification of a potential physiological precursor of aberrant cells in refractory coeliac disease type II. Gut (2012) 1.52
Magnetic resonance imaging surveillance detects early-stage pancreatic cancer in carriers of a p16-Leiden mutation. Gastroenterology (2010) 1.49
Use and efficacy of bone morphogenetic proteins in fracture healing. Int Orthop (2011) 1.49
Classification of low-grade neuroendocrine tumors of midgut and unknown origin. Hum Pathol (2002) 1.47
Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice. Cancer Res (2007) 1.44
DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers. Clin Cancer Res (2008) 1.44
Imbalanced secondary mucosal antioxidant response in inflammatory bowel disease. J Pathol (2003) 1.42
Switching monitoring of emulsified cyclosporine from trough level to 2-hour level in stable liver transplant patients. Liver Transpl (2004) 1.40
Are we ready for top-down therapy for inflammatory bowel diseases: pro. Expert Rev Gastroenterol Hepatol (2007) 1.39
Pretreatment with interferon-γ enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis. Stem Cells (2011) 1.38
Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movements. J Cell Biol (2003) 1.36
Blimp1 regulates the transition of neonatal to adult intestinal epithelium. Nat Commun (2011) 1.36
Fluid shear stress stimulates incorporation of hyaluronan into endothelial cell glycocalyx. Am J Physiol Heart Circ Physiol (2005) 1.35
Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer. Eur J Cancer (2007) 1.33
Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: evidence for antiinflammatory effects of rosuvastatin. Circulation (2003) 1.27
Assessment of serum matrix metalloproteinases MMP-2 and MMP-9 after human liver transplantation: increased serum MMP-9 level in acute rejection. Transplantation (2004) 1.25
A highly conserved arginine in gp120 governs HIV-1 binding to both syndecans and CCR5 via sulfated motifs. J Biol Chem (2005) 1.23
Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion. J Virol (2004) 1.23
Cellular uptake of mammalian heparanase precursor involves low density lipoprotein receptor-related proteins, mannose 6-phosphate receptors, and heparan sulfate proteoglycans. J Biol Chem (2005) 1.22
Histomorphometric analysis reveals reduced bone mass and bone formation in patients with quiescent Crohn's disease. Gastroenterology (2010) 1.21
Nuclear speckles and nucleoli targeting by PIP2-PDZ domain interactions. EMBO J (2005) 1.19
Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands. Steroids (2007) 1.19
Toward MSC in solid organ transplantation: 2008 position paper of the MISOT study group. Transplantation (2009) 1.16
The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer. Cancer (2008) 1.16
Matrix metalloproteinase 2 genotype is associated with nonanastomotic biliary strictures after orthotopic liver transplantation. Liver Int (2011) 1.15
Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy. Ther Drug Monit (2004) 1.14
Distribution and clinical significance of heparan sulfate proteoglycans in ovarian cancer. Clin Cancer Res (2004) 1.13
Glucocorticoid signaling: a nongenomic mechanism for T-cell immunosuppression. Trends Mol Med (2007) 1.13
Complement activation by tubular cells is mediated by properdin binding. Am J Physiol Renal Physiol (2008) 1.12
Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN. EMBO Rep (2006) 1.12
Role of matrix metalloproteinase, tissue inhibitor of metalloproteinase and tumor necrosis factor-alpha single nucleotide gene polymorphisms in inflammatory bowel disease. World J Gastroenterol (2007) 1.12
Syndecan 3 intramembrane proteolysis is presenilin/gamma-secretase-dependent and modulates cytosolic signaling. J Biol Chem (2003) 1.11
Anti-tumor necrosis factor-α antibodies induce regulatory macrophages in an Fc region-dependent manner. Gastroenterology (2010) 1.11
Attenuated mild colonic inflammation and improved survival from severe DSS-colitis of transgenic Cu/Zn-SOD mice. Free Radic Biol Med (2003) 1.10
Preanalytical conditions and circulating matrix metalloproteinases. Transplantation (2005) 1.10
KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium. Blood (2009) 1.08
Heparin II domain of fibronectin uses alpha4beta1 integrin to control focal adhesion and stress fiber formation, independent of syndecan-4. J Biol Chem (2004) 1.08
IBD and arthropathies: a practical approach to its diagnosis and management. Gut (2011) 1.06
Induction of a CXCL8 binding site on endothelial syndecan-3 in rheumatoid synovium. Arthritis Rheum (2005) 1.05
Current use of benzodiazepines in anxiety disorders. Curr Opin Psychiatry (2009) 1.05
Kruppel-like factor 2 improves neovascularization capacity of aged proangiogenic cells. Eur Heart J (2010) 1.04
Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro. Inflamm Bowel Dis (2011) 1.03
Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis. Am J Pathol (2007) 1.03
Distribution of syndecans 1-4 within the anterior segment of the human eye: expression of a variant syndecan-3 and matrix-associated syndecan-2. Exp Eye Res (2004) 1.03
Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease. Gut (2013) 1.02
Intrauterine exposure and pharmacology of conventional thiopurine therapy in pregnant patients with inflammatory bowel disease. Gut (2013) 1.02
Caspase-3 activity predicts local recurrence in rectal cancer. Clin Cancer Res (2007) 1.01
Differential mucosal expression of three superoxide dismutase isoforms in inflammatory bowel disease. J Pathol (2003) 1.01
The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling. Mol Biol Cell (2008) 1.01
Autophagy attenuates the adaptive immune response by destabilizing the immunologic synapse. Gastroenterology (2012) 1.00
Neutralizing antibodies against adeno-associated viruses in inflammatory bowel disease patients: implications for gene therapy. Inflamm Bowel Dis (2011) 0.99