Published in Dev Cell on August 01, 2008
Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells. Blood (2009) 2.65
The extracellular regulation of bone morphogenetic protein signaling. Development (2009) 1.69
Shaping sound in space: the regulation of inner ear patterning. Development (2012) 1.48
A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling. J Cell Biol (2009) 1.39
Spemann's organizer and the self-regulation of embryonic fields. Mech Dev (2009) 1.38
BMPs and chordin regulate patterning of the directive axis in a sea anemone. Proc Natl Acad Sci U S A (2009) 1.24
Organism-scale modeling of early Drosophila patterning via bone morphogenetic proteins. Dev Cell (2010) 1.22
Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation. Dev Biol (2008) 1.15
Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development. Proc Natl Acad Sci U S A (2011) 1.09
Visualisation and quantification of morphogen gradient formation in the zebrafish. PLoS Biol (2009) 1.07
Extracellular regulation of BMP signaling. Curr Biol (2010) 1.07
Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. Genes Dev (2009) 1.04
Loss of the BMP antagonist, SMOC-1, causes Ophthalmo-acromelic (Waardenburg Anophthalmia) syndrome in humans and mice. PLoS Genet (2011) 1.01
Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad. Cytokine Growth Factor Rev (2009) 1.00
Systems biology of the self-regulating morphogenetic gradient of the Xenopus gastrula. Cold Spring Harb Perspect Biol (2009) 0.98
dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity. Dev Biol (2008) 0.96
Crossveinless-2 is required for the relocalization of Chordin protein within the vertebral field in mouse embryos. Dev Biol (2010) 0.95
Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo. Proc Natl Acad Sci U S A (2013) 0.95
Systems control of BMP morphogen flow in vertebrate embryos. Curr Opin Genet Dev (2011) 0.94
BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1. Arterioscler Thromb Vasc Biol (2009) 0.92
Mesendodermal signals required for otic induction: Bmp-antagonists cooperate with Fgf and can facilitate formation of ectopic otic tissue. Dev Dyn (2009) 0.92
BMP signaling in the nephron progenitor niche. Pediatr Nephrol (2011) 0.91
New insights into bone morphogenetic protein signaling: focus on angiogenesis. Curr Opin Hematol (2009) 0.91
Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity. PLoS One (2010) 0.91
Mechanisms driving neural crest induction and migration in the zebrafish and Xenopus laevis. Cell Adh Migr (2011) 0.91
Intriguing extracellular regulation of BMP signaling. Dev Cell (2008) 0.89
BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice. J Biol Chem (2011) 0.85
Dorsal-ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Dev Biol (2011) 0.85
Ancient and diverged TGF-β signaling components in Nasonia vitripennis. Dev Genes Evol (2014) 0.83
Repulsive guidance molecules (RGMs) and neogenin in bone morphogenetic protein (BMP) signaling. Mol Reprod Dev (2013) 0.82
Fine-tuned shuttles for bone morphogenetic proteins. Curr Opin Genet Dev (2013) 0.82
Secreted, receptor-associated bone morphogenetic protein regulators reduce stochastic noise intrinsic to many extracellular morphogen distributions. J R Soc Interface (2011) 0.82
Temporally coordinated signals progressively pattern the anteroposterior and dorsoventral body axes. Semin Cell Dev Biol (2015) 0.80
BMPER regulates cardiomyocyte size and vessel density in vivo. Cardiovasc Pathol (2012) 0.80
The role of chordin fragments generated by partial tolloid cleavage in regulating BMP activity. Biochem Soc Trans (2015) 0.80
The Gyc76C Receptor Guanylyl Cyclase and the Foraging cGMP-Dependent Kinase Regulate Extracellular Matrix Organization and BMP Signaling in the Developing Wing of Drosophila melanogaster. PLoS Genet (2015) 0.77
Expression and functional study of extracellular BMP antagonists during the morphogenesis of the digits and their associated connective tissues. PLoS One (2013) 0.77
Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39. Sci Rep (2016) 0.75
A transmembrane protein EIG121L is required for epidermal differentiation during early embryonic development. J Biol Chem (2010) 0.75
LRP1-Dependent BMPER Signaling Regulates Lipopolysaccharide-Induced Vascular Inflammation. Arterioscler Thromb Vasc Biol (2017) 0.75
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Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell (2006) 2.85
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Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing. Development (2006) 2.58
Twisted gastrulation is a conserved extracellular BMP antagonist. Nature (2001) 2.50
Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity. Cell (1997) 2.44
Evo-devo: variations on ancestral themes. Cell (2008) 2.34
Scaling of the BMP activation gradient in Xenopus embryos. Nature (2008) 2.31
The BMP-binding protein Crossveinless 2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling in Drosophila. Dev Cell (2008) 2.17
Spemann's organizer and self-regulation in amphibian embryos. Nat Rev Mol Cell Biol (2006) 2.05
Wing vein patterning in Drosophila and the analysis of intercellular signaling. Annu Rev Cell Dev Biol (2007) 1.91
Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling. Development (2001) 1.86
BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol Cell Biol (2003) 1.83
Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding. Dev Cell (2008) 1.82
Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in Drosophila. Development (2000) 1.82
Retrocyclin, an antiretroviral theta-defensin, is a lectin. J Immunol (2003) 1.69
Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos. Dev Cell (2003) 1.68
Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulation. Development (2006) 1.57
Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis. Development (2006) 1.50
Extracellular modulation of BMP activity in patterning the dorsoventral axis. Birth Defects Res C Embryo Today (2006) 1.50
von Willebrand factor type C domain-containing proteins regulate bone morphogenetic protein signaling through different recognition mechanisms. J Biol Chem (2007) 1.38
Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins. Biochem Biophys Res Commun (2004) 1.33
An autocatalytic cleavage in the C terminus of the human MUC2 mucin occurs at the low pH of the late secretory pathway. J Biol Chem (2003) 1.26
Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone. Dev Biol (2005) 1.21
A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration. Development (2004) 1.20
BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish. J Mol Cell Cardiol (2007) 1.17
Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning. Development (2004) 1.14
Xolloid-related: a novel BMP1/Tolloid-related metalloprotease is expressed during early Xenopus development. Mech Dev (2002) 1.11
Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms. Development (2004) 1.08
Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascade. Dev Dyn (2004) 1.04
Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling. Mech Dev (2002) 1.01
crossveinless defines a new family of Twisted-gastrulation-like modulators of bone morphogenetic protein signalling. EMBO Rep (2005) 0.99
Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus embryogenesis. Development (2003) 0.94
Is chordin a long-range- or short-range-acting factor? Roles for BMP1-related metalloproteases in chordin and BMP4 autofeedback loop regulation. Dev Biol (2000) 0.94
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