Naoki Kanoh

Author PubWeight™ 19.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin. Chem Biol 2004 1.59
2 The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I. Proc Natl Acad Sci U S A 2008 1.10
3 Syntheses and biological evaluation of irciniastatin A and the C1-C2 alkyne analogue. Org Lett 2010 1.10
4 Syntheses of naturally occurring cytotoxic [7.7]paracyclophanes, (-)-cylindrocyclophane A and its enantiomer, and implications for biological activity. Org Biomol Chem 2009 0.94
5 Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Proc Natl Acad Sci U S A 2006 0.94
6 Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway. Toxicol Lett 2010 0.92
7 Structure-activity relationship of C5-curcuminoids and synthesis of their molecular probes thereof. Bioorg Med Chem 2009 0.89
8 Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells. FEBS Lett 2005 0.87
9 Tremorgenic indole alkaloids. The total synthesis of (-)-penitrem D. J Am Chem Soc 2003 0.85
10 Synthetic studies on daphnicyclidin A: enantiocontrolled construction of the BCD ring system. Org Lett 2009 0.84
11 Total synthesis of methyl sarcophytoate, a marine natural biscembranoid. J Org Chem 2009 0.84
12 Synthesis and biological activities of reveromycin A and spirofungin A derivatives. Bioorg Med Chem Lett 2008 0.83
13 Highly enantioselective intramolecular aza-spiroannulation onto indoles using chiral rhodium catalysis: asymmetric entry to the spiro-beta-lactam core of chartellines. Chem Commun (Camb) 2009 0.82
14 Total synthesis and determination of the absolute configuration of (-)-idesolide. Org Lett 2010 0.81
15 An expedient route to a potent gastrin/CCK-B receptor antagonist (+)-AG-041R. J Org Chem 2009 0.80
16 Detection of cytochrome P450 substrates by using a small-molecule droplet array on an NADH-immobilized solid surface. Chembiochem 2011 0.79
17 Irciniastatin A induces potent and sustained activation of extracellular signal-regulated kinase and thereby promotes ectodomain shedding of tumor necrosis factor receptor 1 in human lung carcinoma A549 cells. Biol Pharm Bull 2015 0.79
18 Studies aimed at the total synthesis of azadirachtin. A modeled connection of C-8 and C-14 in azadirachtin. Org Lett 2002 0.78
19 Total synthesis of methyl sarcophytoate. J Am Chem Soc 2007 0.78
20 Preparation of photo-cross-linked small molecule affinity matrices for affinity selection of protein targets for biologically active small molecules. Methods Mol Biol 2012 0.78
21 Concise entry to both enantiomers of 8-oxabicyclo[3.2.1]oct-3-en-2-one based on novel oxidative etherification: formal synthesis of (+)-sundiversifolide. Org Lett 2011 0.77
22 Structure-affinity relationship study of bleomycins and Shble protein by use of a chemical array. Chembiochem 2009 0.77
23 Eu(OTf)3-catalyzed highly regioselective nucleophilic ring opening of 2,3-epoxy alcohols: an efficient entry to 3-substituted 1,2-diol derivatives. Org Lett 2014 0.77
24 Synthesis and structure-activity relationship of vicenistatin, a cytotoxic 20-membered macrolactam glycoside. Chem Asian J 2012 0.75
25 Reversibility of the thia-Michael reaction of cytotoxic C5-curcuminoid and structure-activity relationship of bis-thiol-adducts thereof. Org Biomol Chem 2016 0.75
26 Synthesis of an enantiomeric DNA oligomer and its T-HgII-T base-pair formation. Nucleic Acids Symp Ser (Oxf) 2007 0.75
27 An improved fluorogenic NAD(P)+ detection method using 2-acetylbenzofuran: its origin and application. Chem Commun (Camb) 2013 0.75
28 Concise, Protecting-Group-Free Synthesis of (+)-Nemonapride via Eu(OTf)3-Catalyzed Aminolysis of 3,4-Epoxy Alcohol. Chem Pharm Bull (Tokyo) 2017 0.75
29 Substrate recognition by a dual functional P450 monooxygenase GfsF involved in FD-891 biosynthesis. Chembiochem 2017 0.75