PubRank

Stefano Volinia

Author PubWeight™ 336.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005 27.56
2 A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 2005 26.02
3 miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A 2005 21.51
4 Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc Natl Acad Sci U S A 2006 10.65
5 MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 2007 9.97
6 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci U S A 2007 9.82
7 MicroRNA signatures in human ovarian cancer. Cancer Res 2007 9.45
8 Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell 2009 8.62
9 The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci U S A 2005 8.60
10 E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 2008 7.56
11 Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature 2007 7.04
12 MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 2009 5.87
13 Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 2006 5.72
14 Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. Lancet Oncol 2009 5.56
15 Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer Cell 2007 5.40
16 MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol 2006 5.40
17 MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia. Blood 2008 5.23
18 Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer. Cancer Res 2008 5.16
19 Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer. Proc Natl Acad Sci U S A 2008 4.79
20 MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci U S A 2008 4.33
21 Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin. Proc Natl Acad Sci U S A 2008 4.26
22 miR-221 overexpression contributes to liver tumorigenesis. Proc Natl Acad Sci U S A 2009 4.15
23 MicroRNA fingerprints during human megakaryocytopoiesis. Proc Natl Acad Sci U S A 2006 3.80
24 MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis. Proc Natl Acad Sci U S A 2008 3.77
25 Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development. Cancer Cell 2010 3.52
26 MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets. J Pathol 2009 3.29
27 A microRNA signature for a BMP2-induced osteoblast lineage commitment program. Proc Natl Acad Sci U S A 2008 3.29
28 MicroRNA 29b functions in acute myeloid leukemia. Blood 2009 3.19
29 Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res 2008 3.16
30 The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature 2002 3.02
31 p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2. J Exp Med 2011 2.93
32 Clinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients. J Clin Oncol 2013 2.86
33 miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer Res 2012 2.52
34 EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers. Nat Med 2011 2.46
35 MicroRNA expression profiling using microarrays. Nat Protoc 2008 2.44
36 MicroRNA microarray identifies Let-7i as a novel biomarker and therapeutic target in human epithelial ovarian cancer. Cancer Res 2008 2.35
37 Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice. Hepatology 2009 2.29
38 microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival. Blood 2010 2.25
39 Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci U S A 2010 2.05
40 Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer. Proc Natl Acad Sci U S A 2011 1.96
41 MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer. J Natl Cancer Inst 2010 1.94
42 Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression. Proc Natl Acad Sci U S A 2010 1.94
43 Epstein-Barr virus-induced miR-155 attenuates NF-kappaB signaling and stabilizes latent virus persistence. J Virol 2008 1.86
44 A methodology for the combined in situ analyses of the precursor and mature forms of microRNAs and correlation with their putative targets. Nat Protoc 2009 1.85
45 Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells. Cancer Res 2010 1.82
46 PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells. J Clin Invest 2013 1.72
47 Karyotype-specific microRNA signature in chronic lymphocytic leukemia. Blood 2009 1.70
48 The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism. J Biol Chem 2008 1.67
49 The down-regulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state. Blood 2012 1.60
50 Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis. Blood 2004 1.59
51 A role for the WWOX gene in prostate cancer. Cancer Res 2006 1.45
52 A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis. Proc Natl Acad Sci U S A 2013 1.44
53 miR-181b is a biomarker of disease progression in chronic lymphocytic leukemia. Blood 2011 1.44
54 Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score. J Clin Oncol 2013 1.34
55 Retracted Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. J Biol Chem 2009 1.33
56 Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer. Proc Natl Acad Sci U S A 2013 1.32
57 Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells. Blood 2009 1.29
58 Non-coding RNAs: a key to future personalized molecular therapy? Genome Med 2010 1.29
59 Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cells. Biochem Pharmacol 2010 1.28
60 Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice. Cancer Res 2006 1.26
61 MicroRNA expression profiling of male breast cancer. Breast Cancer Res 2009 1.22
62 GAMES identifies and annotates mutations in next-generation sequencing projects. Bioinformatics 2010 1.21
63 UCbase & miRfunc: a database of ultraconserved sequences and microRNA function. Nucleic Acids Res 2008 1.19
64 Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis. Endocrinology 2008 1.19
65 MicroRNA expression profiling in human Barrett's carcinogenesis. Int J Cancer 2011 1.17
66 MicroRNA-31 predicts the presence of lymph node metastases and survival in patients with lung adenocarcinoma. Clin Cancer Res 2013 1.17
67 Functional implications of microRNAs in acute myeloid leukemia by integrating microRNA and messenger RNA expression profiling. Cancer 2011 1.16
68 TOM: a web-based integrated approach for identification of candidate disease genes. Nucleic Acids Res 2006 1.15
69 Comparison of microRNA deep sequencing of matched formalin-fixed paraffin-embedded and fresh frozen cancer tissues. PLoS One 2013 1.14
70 In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation. J Exp Med 2013 1.13
71 Altered expression of selected microRNAs in melanoma: antiproliferative and proapoptotic activity of miRNA-155. Int J Oncol 2009 1.11
72 Skin homing of Sézary cells involves SDF-1-CXCR4 signaling and down-regulation of CD26/dipeptidylpeptidase IV. Blood 2005 1.08
73 Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis. Blood 2007 1.07
74 B-cell malignancies in microRNA Eμ-miR-17~92 transgenic mice. Proc Natl Acad Sci U S A 2013 1.06
75 miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model. Proc Natl Acad Sci U S A 2012 1.05
76 Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples. Mod Pathol 2012 1.03
77 Selected microRNAs define cell fate determination of murine central memory CD8 T cells. PLoS One 2010 1.02
78 Zinc replenishment reverses overexpression of the proinflammatory mediator S100A8 and esophageal preneoplasia in the rat. Gastroenterology 2008 1.02
79 Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer. Mol Cancer 2013 1.01
80 Identification of a risk dependent microRNA expression signature in myelodysplastic syndromes. Br J Haematol 2011 1.00
81 Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation. Proc Natl Acad Sci U S A 2011 1.00
82 Strong inverse correlation between microRNA-125b and human papillomavirus DNA in productive infection. Diagn Mol Pathol 2010 0.98
83 Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity. Cancer Res 2014 0.98
84 Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling. Mol Cancer Res 2007 0.95
85 Identification of differentially expressed genes in human salivary gland tumors by DNA microarrays. Mol Cancer Ther 2002 0.95
86 TOM: enhancement and extension of a tool suite for in silico approaches to multigenic hereditary disorders. Bioinformatics 2007 0.94
87 Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancer. Cancer 2009 0.93
88 Common fragile site tumor suppressor genes and corresponding mouse models of cancer. J Biomed Biotechnol 2010 0.93
89 Analysis of MG63 osteoblastic-cell response to a new nanoporous implant surface by means of a microarray technology. Clin Oral Implants Res 2004 0.92
90 MicroRNA expression signatures in solid malignancies. Cancer J 2012 0.92
91 Toll-like receptor 3 (TLR3) activation induces microRNA-dependent reexpression of functional RARβ and tumor regression. Proc Natl Acad Sci U S A 2013 0.92
92 GAM/ZFp/ZNF512B is central to a gene sensor circuitry involving cell-cycle regulators, TGF{beta} effectors, Drosha and microRNAs with opposite oncogenic potentials. Nucleic Acids Res 2010 0.91
93 Expression profiles of craniosynostosis-derived fibroblasts. Mol Med 2002 0.88
94 OMiR: Identification of associations between OMIM diseases and microRNAs. Genomics 2010 0.87
95 Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML. Blood 2014 0.87
96 Molecular classification of nodal metastasis in primary larynx squamous cell carcinoma. Transl Res 2007 0.86
97 SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome. J Clin Invest 2014 0.86
98 Nuclear phosphoinositide 3-kinase C2beta activation during G2/M phase of the cell cycle in HL-60 cells. Biochim Biophys Acta 2003 0.86
99 Next generation analysis of breast cancer genomes for precision medicine. Cancer Lett 2013 0.85
100 Zirconium oxide: analysis of MG63 osteoblast-like cell response by means of a microarray technology. Biomaterials 2004 0.85
101 inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations. Blood 2012 0.84
102 The activation of nuclear phosphoinositide 3-kinase C2beta in all-trans-retinoic acid-differentiated HL-60 cells. FEBS Lett 2002 0.84
103 Gene expression analysis in HBV transgenic mouse liver: a model to study early events related to hepatocarcinogenesis. Mol Med 2006 0.83
104 P-15 cell-binding domain derived from collagen: analysis of MG63 osteoblastic-cell response by means of a microarray technology. J Periodontol 2004 0.83
105 Association between idiopathic hearing loss and mitochondrial DNA mutations: a study on 169 hearing-impaired subjects. Int J Mol Med 2013 0.83
106 Cytogenetic and array CGH characterization of an intrachromosomal complex rearrangement of 4q in a patient with a 4q-phenotype. Am J Med Genet A 2008 0.82
107 MicroRNA Expression Profiling in the Histological Subtypes of Barrett's Metaplasia. Clin Transl Gastroenterol 2013 0.82
108 Hepatocyte growth factor activates phosphoinositide 3-kinase C2 beta in renal brush-border plasma membranes. Biochem J 2002 0.80
109 Nanotechnologies and microchips in genetic diseases. J Nephrol 2003 0.80
110 Overexpression of miR-9 in mast cells is associated with invasive behavior and spontaneous metastasis. BMC Cancer 2014 0.80
111 An expression atlas of connexin genes in the mouse. Genomics 2004 0.80
112 Akt, protein kinase C, and mitogen-activated protein kinase phosphorylation status in head and neck squamous cell carcinoma. Head Neck 2005 0.80
113 Finding biological process modifications in cancer tissues by mining gene expression correlations. BMC Bioinformatics 2006 0.79
114 P253R fibroblast growth factor receptor-2 mutation induces RUNX2 transcript variants and calvarial osteoblast differentiation. J Cell Physiol 2005 0.79
115 Analysis of osteoblast-like MG63 cells' response to a rough implant surface by means of DNA microarray. J Oral Implantol 2003 0.79
116 Fhit loss in lung preneoplasia: relation to DNA damage response checkpoint activation. Cancer Lett 2010 0.79
117 Genetic profile of clear cell odontogenic carcinoma. J Craniofac Surg 2003 0.78
118 Compatible solutes from hyperthermophiles improve the quality of DNA microarrays. BMC Biotechnol 2007 0.78
119 RNA expression induced by cisplatin in an organ of Corti-derived immortalized cell line. Hear Res 2004 0.78
120 Prion proteins (PRNP and PRND) are over-expressed in osteosarcoma. J Orthop Res 2011 0.78
121 Microarray and large-scale in silico--based identification of genes functionally related to Haptoglobin and/or Hemopexin. DNA Cell Biol 2006 0.77
122 Evidence of genetic underexpression in chorionic villi samples of euploid fetuses with increased nuchal translucency at 10-11 weeks' gestation. Prenat Diagn 2006 0.77
123 Genes transcriptionally modulated by interferon alpha2a correlate with the cytokine activity. Haematologica 2004 0.77
124 Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development. Cancer Cell 2016 0.76
125 Fun&Co: identification of key functional differences in transcriptomes. Bioinformatics 2007 0.76
126 A unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. J Biol Chem 2016 0.75
127 Correction: In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation. J Exp Med 2017 0.75