Hextan Y S Ngan

Author PubWeight™ 86.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection. Nat Genet 2005 2.82
2 Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation. Carcinogenesis 2008 1.73
3 Effect of individual psychological intervention in Chinese women with gynecologic malignancy: a randomized controlled trial. J Clin Oncol 2005 1.58
4 p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients. Proc Natl Acad Sci U S A 2010 1.50
5 Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells. Carcinogenesis 2008 1.49
6 p70 S6 kinase promotes epithelial to mesenchymal transition through snail induction in ovarian cancer cells. Cancer Res 2008 1.38
7 Single-dose methotrexate regimen in the treatment of low-risk gestational trophoblastic neoplasia. Am J Obstet Gynecol 2006 1.38
8 Evaluation of a newly developed GenoArray human papillomavirus (HPV) genotyping assay and comparison with the Roche Linear Array HPV genotyping assay. J Clin Microbiol 2009 1.37
9 The increase of mitochondrial DNA content in endometrial adenocarcinoma cells: a quantitative study using laser-captured microdissected tissues. Gynecol Oncol 2005 1.36
10 Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data. BMC Cancer 2006 1.34
11 TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies. Lancet Oncol 2009 1.26
12 Epigenetic factors controlling the BRCA1 and BRCA2 genes in sporadic ovarian cancer. Cancer Res 2002 1.23
13 Coexistence of struma ovarii with marked ascites and elevated CA-125 levels: case report and literature review. Arch Gynecol Obstet 2008 1.22
14 Tyrosine kinase B receptor and BDNF expression in ovarian cancers - Effect on cell migration, angiogenesis and clinical outcome. Cancer Lett 2009 1.21
15 Differential expression and phosphorylation of Pak1 and Pak2 in ovarian cancer: effects on prognosis and cell invasion. Int J Cancer 2010 1.19
16 Mitochondrial DNA variant 16189T>C is associated with susceptibility to endometrial cancer. Hum Mutat 2003 1.16
17 Loss of Programmed cell death 4 (Pdcd4) associates with the progression of ovarian cancer. Mol Cancer 2009 1.16
18 Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer. Oncotarget 2012 1.12
19 Semi-quantitative fluorescent PCR analysis identifies PRKAA1 on chromosome 5 as a potential candidate cancer gene of cervical cancer. Gynecol Oncol 2006 1.12
20 Transcriptional repression of WEE1 by Kruppel-like factor 2 is involved in DNA damage-induced apoptosis. Oncogene 2005 1.12
21 Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells. Endocrinology 2006 1.12
22 Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells. PLoS One 2011 1.11
23 Tumor suppressor effect of follistatin-like 1 in ovarian and endometrial carcinogenesis: a differential expression and functional analysis. Carcinogenesis 2008 1.11
24 Symptoms, coping strategies, and timing of presentations in patients with newly diagnosed ovarian cancer. Gynecol Oncol 2003 1.10
25 Analysis of gestational trophoblastic disease by genotyping and chromosome in situ hybridization. Mod Pathol 2004 1.09
26 iASPP and chemoresistance in ovarian cancers: effects on paclitaxel-mediated mitotic catastrophe. Clin Cancer Res 2011 1.09
27 Quality of life in women treated with neoadjuvant chemotherapy for advanced ovarian cancer: a prospective longitudinal study. Gynecol Oncol 2003 1.08
28 Promoter hypermethylation of multiple genes in hydatidiform mole and choriocarcinoma. J Mol Diagn 2004 1.05
29 AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activity. PLoS One 2013 1.02
30 Overexpression of NANOG in gestational trophoblastic diseases: effect on apoptosis, cell invasion, and clinical outcome. Am J Pathol 2008 1.01
31 Beliefs about cervical cancer and human papillomavirus (HPV) and acceptability of HPV vaccination among Chinese women in Hong Kong. Prev Med 2007 1.01
32 Down-regulation and promoter methylation of tissue inhibitor of metalloproteinase 3 in choriocarcinoma. Gynecol Oncol 2004 1.01
33 Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer. Oncotarget 2014 0.99
34 Genetic abnormalities and HPV status in cervical and vulvar squamous cell carcinomas. Cancer Genet Cytogenet 2005 0.99
35 Differential functions of growth factor receptor-bound protein 7 (GRB7) and its variant GRB7v in ovarian carcinogenesis. Clin Cancer Res 2010 0.99
36 Aberrant activation of hedgehog signaling pathway contributes to endometrial carcinogenesis through beta-catenin. Mod Pathol 2009 0.98
37 Recurrent BRCA1 and BRCA2 germline mutations in ovarian cancer: a founder mutation of BRCA1 identified in the Chinese population. Hum Mutat 2002 0.98
38 Retracted Overexpressed PAK4 promotes proliferation, migration and invasion of choriocarcinoma. Carcinogenesis 2011 0.98
39 The effect of school-based cervical cancer education on perceptions towards human papillomavirus vaccination among Hong Kong Chinese adolescent girls. Patient Educ Couns 2010 0.98
40 Establishment and characterization of a human first-trimester extravillous trophoblast cell line (TEV-1). J Soc Gynecol Investig 2005 0.97
41 Coexisting epithelioid trophoblastic tumor and choriocarcinoma of the uterus following a chemoresistant hydatidiform mole. Arch Pathol Lab Med 2003 0.96
42 Tumour suppressive function and modulation of programmed cell death 4 (PDCD4) in ovarian cancer. PLoS One 2012 0.96
43 Age-period-cohort analysis of cervical cancer incidence in Hong Kong from 1972 to 2001 using maximum likelihood and Bayesian methods. J Epidemiol Community Health 2006 0.95
44 The use of music to reduce anxiety for patients undergoing colposcopy: a randomized trial. Gynecol Oncol 2003 0.95
45 Estrogen receptor subtypes in ovarian cancer: a clinical correlation. Obstet Gynecol 2008 0.95
46 Increased expression of PITX2 transcription factor contributes to ovarian cancer progression. PLoS One 2012 0.94
47 Paradoxical impact of two folate receptors, FRα and RFC, in ovarian cancer: effect on cell proliferation, invasion and clinical outcome. PLoS One 2012 0.94
48 Trophoblastic disease review for diagnosis and management: a joint report from the International Society for the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup. Int J Gynecol Cancer 2014 0.93
49 Endocrine gland-derived vascular endothelial growth factor is expressed in human peri-implantation endometrium, but not in endometrial carcinoma. Endocrinology 2005 0.93
50 Metastatic trophoblastic disease after an initial diagnosis of partial hydatidiform mole: genotyping and chromosome in situ hybridization analysis. Cancer 2004 0.93
51 Promoter methylation and differential expression of pi-class glutathione S-transferase in endometrial carcinoma. J Mol Diagn 2005 0.92
52 Epidemiology of human papillomavirus infection and cervical cancer and future perspectives in Hong Kong, Singapore and Taiwan. Vaccine 2008 0.92
53 Overexpression of proto-oncogene FBI-1 activates membrane type 1-matrix metalloproteinase in association with adverse outcome in ovarian cancers. Mol Cancer 2010 0.92
54 Transforming growth factor beta1 promotes chromosomal instability in human papillomavirus 16 E6E7-infected cervical epithelial cells. Cancer Res 2008 0.90
55 Targeting GRB7/ERK/FOXM1 signaling pathway impairs aggressiveness of ovarian cancer cells. PLoS One 2012 0.90
56 Hypermethylation of SOX2 gene in hydatidiform mole and choriocarcinoma. Reprod Sci 2008 0.89
57 p21-Activated kinase-1 promotes aggressive phenotype, cell proliferation, and invasion in gestational trophoblastic disease. Am J Pathol 2010 0.88
58 Gestational trophoblastic disease. Best Pract Res Clin Obstet Gynaecol 2012 0.88
59 Cervical cancer burden and prevention strategies: Asia Oceania perspective. Cancer Epidemiol Biomarkers Prev 2012 0.87
60 Comparison of human papillomavirus DNA levels in gynecological cancers: implication for cancer development. Tumour Biol 2004 0.87
61 HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis. J Med Virol 2015 0.86
62 Dysregulated stemness-related genes in gynecological malignancies. Histol Histopathol 2012 0.86
63 Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells. J Pathol 2011 0.85
64 Who receives, benefits from and is harmed by cervical and breast cancer screening among Hong Kong Chinese? J Public Health (Oxf) 2008 0.84
65 Distribution of six oncogenic types of human papillomavirus and type 16 integration analysis in Chinese women with cervical precancerous lesions and carcinomas. Tumour Biol 2008 0.83
66 Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival. Histopathology 2011 0.83
67 Malignant placental site trophoblastic tumor: a cytogenetic study using comparative genomic hybridization and chromosome in situ hybridization. Cancer 2002 0.81
68 Frequent occurrence of mitochondrial microsatellite instability in the D-loop region of human cancers. Ann N Y Acad Sci 2005 0.81
69 Asian society of gynecologic oncology workshop 2010. J Gynecol Oncol 2010 0.81
70 Staging of uterine sarcomas. Best Pract Res Clin Obstet Gynaecol 2011 0.81
71 De-stigmatising human papillomavirus in the context of cervical cancer: a randomised controlled trial. Psychooncology 2010 0.81
72 Single nucleotide polymorphism of pi-class glutathione s-transferase and susceptibility to endometrial carcinoma. Clin Cancer Res 2005 0.80
73 Mcl-1 expression in gestational trophoblastic disease correlates with clinical outcome: a differential expression study. Cancer 2005 0.79
74 Psychological burden of testing positive for high-risk human papillomavirus on women with atypical cervical cytology: a prospective study. Acta Obstet Gynecol Scand 2011 0.79
75 Assessment of knowledge and stigmatizing attitudes related to human papillomavirus among Hong Kong Chinese healthcare providers. Int J Gynaecol Obstet 2011 0.79
76 Association of ICAM3 genetic variant with severe acute respiratory syndrome. J Infect Dis 2007 0.79
77 Downregulation of ASPP1 in gestational trophoblastic disease: correlation with hypermethylation, apoptotic activity and clinical outcome. Mod Pathol 2010 0.79
78 Screening for HIV infection in women with newly diagnosed cervical cancer. Gynecol Oncol 2004 0.78
79 Comparison of the GenoFlow human papillomavirus (HPV) test and the Linear Array assay for HPV screening in an Asian population. J Clin Microbiol 2012 0.78
80 Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src signaling pathway activation. Carcinogenesis 2013 0.78
81 Detection of mosaic pattern of mitochondrial DNA alterations in different populations of cells from the same endometrial tumor. Mitochondrion 2006 0.77
82 Human female reproductive tract epithelial cell culture. Methods Mol Biol 2013 0.77
83 Proliferation to apoptosis ratio as a prognostic marker in adenocarcinoma of uterine cervix. Gynecol Oncol 2004 0.77
84 Differential expression of insulin-like growth factor binding protein 1 and ferritin light polypeptide in gestational trophoblastic neoplasia: combined cDNA suppression subtractive hybridization and microarray study. Cancer 2005 0.77
85 Human papillomavirus vaccine: what are women most concerned about? J Obstet Gynaecol Res 2011 0.77
86 Detection of mitochondrial DNA mutations in gestational trophoblastic disease. Hum Mutat 2003 0.76
87 Hepatic arteriogram for gestational trophoblastic tumor: is it useful? Cancer Invest 2005 0.75
88 Apoptotic and proliferative activity in ovarian benign, borderline and malignant tumors. Chin Med Sci J 2002 0.75
89 Preface. Uterine sarcoma. Best Pract Res Clin Obstet Gynaecol 2011 0.75
90 Ovarian clear cell carcinoma with choriocarcinomatous differentiation: report of a rare and aggressive tumor. Int J Gynecol Pathol 2010 0.75
91 c-mos immunoreactivity aids in the diagnosis of gestational trophoblastic lesions. Int J Gynecol Pathol 2004 0.75