Published in Methods Enzymol on January 01, 2008
Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood (2009) 2.73
Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice. Nat Protoc (2010) 2.12
Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices. Blood (2009) 2.04
Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events. Blood (2010) 1.98
Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF. Proc Natl Acad Sci U S A (2010) 1.67
The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Dev Cell (2013) 1.54
A Novel Three-Dimensional Human Peritubular Microvascular System. J Am Soc Nephrol (2015) 1.52
Matrix composition regulates three-dimensional network formation by endothelial cells and mesenchymal stem cells in collagen/fibrin materials. Angiogenesis (2012) 1.47
VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines. Blood (2011) 1.46
Biomimetic model to reconstitute angiogenic sprouting morphogenesis in vitro. Proc Natl Acad Sci U S A (2013) 1.44
Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents. J Clin Invest (2010) 1.42
Angiogenesis. Cold Spring Harb Perspect Biol (2011) 1.37
Molecular basis for endothelial lumen formation and tubulogenesis during vasculogenesis and angiogenic sprouting. Int Rev Cell Mol Biol (2011) 1.36
Investigating endothelial invasion and sprouting behavior in three-dimensional collagen matrices. Nat Protoc (2009) 1.26
Non-thermal dielectric barrier discharge plasma induces angiogenesis through reactive oxygen species. J R Soc Interface (2011) 1.24
Endothelial cell-pericyte interactions stimulate basement membrane matrix assembly: influence on vascular tube remodeling, maturation, and stabilization. Microsc Microanal (2011) 1.20
Molecular mechanisms controlling vascular lumen formation in three-dimensional extracellular matrices. Cells Tissues Organs (2011) 1.19
Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-catenin. J Biol Chem (2011) 1.14
In vitro engineering of vascularized tissue surrogates. Sci Rep (2013) 1.08
Astrocytes and pericytes differentially modulate blood-brain barrier characteristics during development and hypoxic insult. J Cereb Blood Flow Metab (2010) 1.08
Unforeseen decreases in dissolved oxygen levels affect tube formation kinetics in collagen gels. Am J Physiol Cell Physiol (2011) 1.05
Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth. Dev Cell (2012) 1.04
RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG. Blood (2011) 1.02
The role of pericyte detachment in vascular rarefaction. J Vasc Res (2014) 0.98
Recreating the perivascular niche ex vivo using a microfluidic approach. Biotechnol Bioeng (2010) 0.94
Matrix rigidity activates Wnt signaling through down-regulation of Dickkopf-1 protein. J Biol Chem (2012) 0.93
Creating perfused functional vascular channels using 3D bio-printing technology. Biomaterials (2014) 0.93
Bevacizumab and breast cancer: what does the future hold? Future Oncol (2012) 0.92
TGF-β1 induces endothelial cell apoptosis by shifting VEGF activation of p38(MAPK) from the prosurvival p38β to proapoptotic p38α. Mol Cancer Res (2012) 0.90
Ancestral vascular lumen formation via basal cell surfaces. PLoS One (2009) 0.90
Human tumor cells induce angiogenesis through positive feedback between CD147 and insulin-like growth factor-I. PLoS One (2012) 0.90
Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions. PLoS One (2013) 0.88
Angiogenic sprouting is regulated by endothelial cell expression of Slug. J Cell Sci (2014) 0.88
Capillary morphogenesis in PEG-collagen hydrogels. Biomaterials (2013) 0.87
Angiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cells. PLoS One (2012) 0.86
ADAMTS-4 and biglycan are expressed at high levels and co-localize to podosomes during endothelial cell tubulogenesis in vitro. J Histochem Cytochem (2013) 0.85
Aligned human microvessels formed in 3D fibrin gel by constraint of gel contraction. Microvasc Res (2013) 0.85
Pericyte regulation of vascular remodeling through the CXC receptor 3. Arterioscler Thromb Vasc Biol (2013) 0.85
How blood vessel networks are made and measured. Cells Tissues Organs (2011) 0.84
Annexin 2 regulates endothelial morphogenesis by controlling AKT activation and junctional integrity. J Biol Chem (2010) 0.84
A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis. Cell Death Dis (2013) 0.84
CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis. Blood (2012) 0.84
Screening assay for blood vessel maturation inhibitors. Biochem Biophys Res Commun (2013) 0.84
Single-cell analysis of endothelial morphogenesis in vivo. Development (2015) 0.83
EB1, p150Glued, and Clasp1 control endothelial tubulogenesis through microtubule assembly, acetylation, and apical polarization. Blood (2013) 0.83
Polysaccharide hydrogels with tunable stiffness and provasculogenic properties via α-helix to β-sheet switch in secondary structure. Proc Natl Acad Sci U S A (2013) 0.82
Cell invasion in the spheroid sprouting assay: a spatial organisation analysis adaptable to cell behaviour. PLoS One (2014) 0.81
Vasculogenic dynamics in 3D engineered tissue constructs. Sci Rep (2015) 0.81
Pattern formation during vasculogenesis. Birth Defects Res C Embryo Today (2012) 0.81
Vascular Network Formation in Expanding versus Static Tissues: Embryos and Tumors. Genes Cancer (2011) 0.80
Adipose-derived endothelial and mesenchymal stem cells enhance vascular network formation on three-dimensional constructs in vitro. Stem Cell Res Ther (2016) 0.80
Angiopoietin-like protein 2 regulates endothelial colony forming cell vasculogenesis. Angiogenesis (2014) 0.80
Generation of Multi-Scale Vascular Network System within 3D Hydrogel using 3D Bio-Printing Technology. Cell Mol Bioeng (2014) 0.80
Activation of the Wnt/planar cell polarity pathway is required for pericyte recruitment during pulmonary angiogenesis. Am J Pathol (2014) 0.80
The hematopoietic chemokine CXCL12 promotes integration of human endothelial colony forming cell-derived cells into immature vessel networks. Stem Cells Dev (2014) 0.80
Improved Angiogenesis in Response to Localized Delivery of Macrophage-Recruiting Molecules. PLoS One (2015) 0.80
Interferon-induced transmembrane protein 1 regulates endothelial lumen formation during angiogenesis. Arterioscler Thromb Vasc Biol (2014) 0.79
Actin remodeling by Nck regulates endothelial lumen formation. Mol Biol Cell (2015) 0.78
Endothelial cell motility, coordination and pattern formation during vasculogenesis. Wiley Interdiscip Rev Syst Biol Med (2013) 0.78
Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth. Biomaterials (2016) 0.78
Endothelial cell dynamics during anastomosis in vitro. Integr Biol (Camb) (2015) 0.78
Systems biology of the microvasculature. Integr Biol (Camb) (2015) 0.77
Zebrafish stromal cells have endothelial properties and support hematopoietic cells. Exp Hematol (2011) 0.77
mTORC2 mediates CXCL12-induced angiogenesis. Angiogenesis (2016) 0.76
Assays to examine endothelial cell migration, tube formation, and gene expression profiles. Methods Mol Biol (2014) 0.76
CECR1-mediated cross talk between macrophages and vascular mural cells promotes neovascularization in malignant glioma. Oncogene (2017) 0.76
Fluid pressure is a magnitude-dependent modulator of early endothelial tubulogenic activity: implications related to a potential tissue-engineering control parameter. Tissue Eng Part A (2012) 0.75
In Vitro Multitissue Interface Model Supports Rapid Vasculogenesis and Mechanistic Study of Vascularization across Tissue Compartments. ACS Appl Mater Interfaces (2016) 0.75
Matrix rigidity regulates spatiotemporal dynamics of Cdc42 activity and vacuole formation kinetics of endothelial colony forming cells. Biochem Biophys Res Commun (2014) 0.75
VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation. Mol Biol Cell (2016) 0.75
Activation of Apoptotic Signal in Endothelial Cells through Intracellular Signaling Molecules Blockade in Tumor-Induced Angiogenesis. Biomed Res Int (2015) 0.75
Platelet lysate gel and endothelial progenitors stimulate microvascular network formation in vitro: tissue engineering implications. Sci Rep (2016) 0.75
Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish. FASEB J (2015) 0.75
Cell Adhesion Mediated by VCAM-ITGα9 Interactions Enables Lymphatic Development. Arterioscler Thromb Vasc Biol (2015) 0.75
Src- and Fyn-dependent apical membrane trafficking events control endothelial lumen formation during vascular tube morphogenesis. PLoS One (2017) 0.75
The functional relationship between transglutaminase 2 and transforming growth factor β1 in the regulation of angiogenesis and endothelial-mesenchymal transition. Cell Death Dis (2017) 0.75
Endothelial tubes assemble from intracellular vacuoles in vivo. Nature (2006) 4.46
The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases. Nat Med (2009) 3.05
Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood (2009) 2.73
Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J Cell Biol (2006) 2.50
Cellular and molecular mechanisms of vascular lumen formation. Dev Cell (2009) 2.45
Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling. J Cell Sci (2008) 2.43
Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. J Clin Invest (2006) 2.40
The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices. J Cell Sci (2002) 2.05
Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices. Blood (2009) 2.04
Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events. Blood (2010) 1.98
Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis. Am J Hum Genet (2003) 1.86
Mechanisms controlling human endothelial lumen formation and tube assembly in three-dimensional extracellular matrices. Birth Defects Res C Embryo Today (2007) 1.84
Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization. Blood (2010) 1.81
alpha(4)beta(1) Integrin activation of L-type calcium channels in vascular smooth muscle causes arteriole vasoconstriction. Circ Res (2002) 1.74
MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. J Cell Sci (2005) 1.74
Sphingosine-1-phosphate markedly induces matrix metalloproteinase and integrin-dependent human endothelial cell invasion and lumen formation in three-dimensional collagen and fibrin matrices. Biochem Biophys Res Commun (2003) 1.55
Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. Dev Cell (2011) 1.55
Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury. J Am Soc Nephrol (2012) 1.48
Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation. J Cell Sci (2009) 1.47
VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines. Blood (2011) 1.46
Mechanical properties of the interaction between fibronectin and alpha5beta1-integrin on vascular smooth muscle cells studied using atomic force microscopy. Am J Physiol Heart Circ Physiol (2005) 1.37
Angiogenesis. Cold Spring Harb Perspect Biol (2011) 1.37
Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice. J Clin Invest (2011) 1.36
Molecular basis for endothelial lumen formation and tubulogenesis during vasculogenesis and angiogenic sprouting. Int Rev Cell Mol Biol (2011) 1.36
MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices. J Cell Sci (2009) 1.33
Integrins as unique receptors for vascular control. J Vasc Res (2003) 1.33
3D timelapse analysis of muscle satellite cell motility. Stem Cells (2009) 1.30
Microtubule depolymerization rapidly collapses capillary tube networks in vitro and angiogenic vessels in vivo through the small GTPase Rho. J Biol Chem (2003) 1.30
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling. Mol Cancer (2006) 1.22
Endothelial cell-pericyte interactions stimulate basement membrane matrix assembly: influence on vascular tube remodeling, maturation, and stabilization. Microsc Microanal (2011) 1.20
Molecular mechanisms controlling vascular lumen formation in three-dimensional extracellular matrices. Cells Tissues Organs (2011) 1.19
Integrin receptor activation triggers converging regulation of Cav1.2 calcium channels by c-Src and protein kinase A pathways. J Biol Chem (2006) 1.16
ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene. J Biol Chem (2012) 1.11
Potentiation of large conductance, Ca2+-activated K+ (BK) channels by alpha5beta1 integrin activation in arteriolar smooth muscle. J Physiol (2008) 1.04
Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth. Dev Cell (2012) 1.04
RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG. Blood (2011) 1.02
Transforming growth factor-beta-stimulated endocardial cell transformation is dependent on Par6c regulation of RhoA. J Biol Chem (2008) 1.01
State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association. Circ Res (2015) 0.94
Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation. J Biol Chem (2009) 0.94
Ischemia-induced cleavage of cadherins in NRK cells: evidence for a role of metalloproteinases. Am J Physiol Renal Physiol (2005) 0.91
Coordinated regulation of vascular Ca2+ and K+ channels by integrin signaling. Adv Exp Med Biol (2010) 0.89
Minimal pre-mRNA substrates with natural and converted sites for full-round U insertion and U deletion RNA editing in trypanosomes. Nucleic Acids Res (2005) 0.88
Regulation of Ca2+-dependent K+ current by alphavbeta3 integrin engagement in vascular endothelium. J Biol Chem (2004) 0.88
Determinants for association and guide RNA-directed endonuclease cleavage by purified RNA editing complexes from Trypanosoma brucei. J Mol Biol (2008) 0.87
Short and long term variation in ultraviolet radiation and multiple sclerosis. Int J Environ Res Public Health (2012) 0.86
The ansacarbamitocins: polar ansamitocin derivatives. J Nat Prod (2007) 0.86
Aligned human microvessels formed in 3D fibrin gel by constraint of gel contraction. Microvasc Res (2013) 0.85
CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis. Blood (2012) 0.84
Control of vascular tube morphogenesis and maturation in 3D extracellular matrices by endothelial cells and pericytes. Methods Mol Biol (2013) 0.83
EB1, p150Glued, and Clasp1 control endothelial tubulogenesis through microtubule assembly, acetylation, and apical polarization. Blood (2013) 0.83
Spatial association of the Cav1.2 calcium channel with α5β1-integrin. Am J Physiol Cell Physiol (2010) 0.83
The effect of solar cycles on human lifespan in the 50 United states: variation in light affects the human genome. Med Hypotheses (2010) 0.82
Blood coagulation and blood vessel development: is tissue factor the missing link? Arterioscler Thromb Vasc Biol (2011) 0.81
The light of life: evidence that the sun modulates human lifespan. Med Hypotheses (2007) 0.81
Investigating human vascular tube morphogenesis and maturation using endothelial cell-pericyte co-cultures and a doxycycline-inducible genetic system in 3D extracellular matrices. Methods Mol Biol (2015) 0.79
The development of the vasculature and its extracellular matrix: a gradual process defined by sequential cellular and matrix remodeling events. Am J Physiol Heart Circ Physiol (2010) 0.77
Preferential interaction of a 25kDa protein with an A6 pre-mRNA substrate for RNA editing in Trypanosoma brucei. Int J Parasitol (2006) 0.75
Guanosine triphosphatase activation occurs downstream of calcineurin in cardiac hypertrophy*. J Investig Med (2005) 0.75