E Van Cutsem

Author PubWeight™ 126.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab. Ann Oncol 2007 5.68
2 ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making. Ann Oncol 2012 5.32
3 Final results of a randomized phase III trial of sequential high-dose methotrexate, fluorouracil, and doxorubicin versus etoposide, leucovorin, and fluorouracil versus infusional fluorouracil and cisplatin in advanced gastric cancer: A trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group. J Clin Oncol 2000 4.25
4 Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet 1998 4.16
5 Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: summary findings of an independent panel. J Clin Oncol 2001 3.21
6 First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous 5-fluorouracil/leucovorin. Ann Oncol 2002 2.87
7 Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors. Ann Oncol 2005 2.84
8 Utility of positron emission tomography for the staging of patients with potentially operable esophageal carcinoma. J Clin Oncol 2000 2.77
9 Positron emission tomography for assessment of the response to induction radiochemotherapy in locally advanced oesophageal cancer. Ann Oncol 2002 2.60
10 The current and future role of the medical oncologist in the professional care for cancer patients: a position paper by the European Society for Medical Oncology (ESMO). Ann Oncol 2013 2.53
11 Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). Oncogene 1999 2.10
12 Combination of surgery and chemotherapy and the role of targeted agents in the treatment of patients with colorectal liver metastases: recommendations from an expert panel. Ann Oncol 2009 1.93
13 Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004). Ann Oncol 2012 1.84
14 Clinical and psychometric validation of a questionnaire module, the EORTC QLQ-STO 22, to assess quality of life in patients with gastric cancer. Eur J Cancer 2004 1.70
15 Primary liver tumour of intermediate (hepatocyte-bile duct cell) phenotype: a progenitor cell tumour? Liver 1998 1.67
16 Pancreatic adenocarcinoma: ESMO-ESDO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2012 1.67
17 Combination therapy of experimental histoplasmosis and cryptococcosis with amphotericin B and ketoconazole. Rev Infect Dis 1981 1.58
18 A randomised phase II trial of weekly high-dose 5-fluorouracil with and without folinic acid and cisplatin in patients with advanced biliary tract carcinoma: results of the 40955 EORTC trial. Eur J Cancer 2005 1.58
19 Two or three year disease-free survival (DFS) as a primary end-point in stage III adjuvant colon cancer trials with fluoropyrimidines with or without oxaliplatin or irinotecan: data from 12,676 patients from MOSAIC, X-ACT, PETACC-3, C-06, C-07 and C89803. Eur J Cancer 2011 1.57
20 Ambulatory gastrojejunal manometry in severe motility-like dyspepsia: lack of correlation between dysmotility, symptoms, and gastric emptying. Gut 1998 1.54
21 Modelling the polypeptide backbone with 'spare parts' from known protein structures. Protein Eng 1989 1.54
22 European guidelines for quality assurance in colorectal cancer screening and diagnosis: overview and introduction to the full supplement publication. Endoscopy 2012 1.44
23 Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015. Ann Oncol 2007 1.44
24 The management of pancreatic cancer. Current expert opinion and recommendations derived from the 8th World Congress on Gastrointestinal Cancer, Barcelona, 2006. Ann Oncol 2007 1.44
25 Erythromycin accelerates gastric emptying by inducing antral contractions and improved gastroduodenal coordination. Gastroenterology 1992 1.33
26 Radiological tumor size decrease at week 6 is a potent predictor of outcome in chemorefractory metastatic colorectal cancer treated with cetuximab (BOND trial). Ann Oncol 2009 1.29
27 Treatment of the elderly colorectal cancer patient: SIOG expert recommendations. Ann Oncol 2008 1.29
28 Metastatic colorectal cancer: integrating irinotecan into combination and sequential chemotherapy. Ann Oncol 2003 1.26
29 The management of hepatocellular carcinoma. Current expert opinion and recommendations derived from the 10th World Congress on Gastrointestinal Cancer, Barcelona, 2008. Ann Oncol 2009 1.26
30 Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial. Br J Cancer 2009 1.25
31 Intravenous erythromycin dramatically accelerates gastric emptying in gastroparesis diabeticorum and normals and abolishes the emptying discrimination between solids and liquids. J Nucl Med 1990 1.22
32 Unexplained rising carcinoembryonic antigen (CEA) in the postoperative surveillance of colorectal cancer: the utility of positron emission tomography (PET). Eur J Cancer 2001 1.19
33 Additional value of whole-body positron emission tomography with fluorine-18-2-fluoro-2-deoxy-D-glucose in recurrent colorectal cancer. J Clin Oncol 1999 1.19
34 Whole-body PET with FDG for the diagnosis of recurrent gastric cancer. Eur J Nucl Med Mol Imaging 2002 1.17
35 Patient acceptance for CT colonography: what is the real issue? Eur Radiol 2002 1.15
36 Association of progression-free survival with patient-reported outcomes and survival: results from a randomised phase 3 trial of panitumumab. Br J Cancer 2007 1.15
37 Open, randomized, multicenter trial of raltitrexed versus fluorouracil plus high-dose leucovorin in patients with advanced colorectal cancer. Tomudex Colorectal Cancer Study Group. J Clin Oncol 1998 1.14
38 'Tomudex' (ZD1694): results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia. The 'Tomudex' Colorectal Cancer Study Group. Eur J Cancer 1995 1.12
39 Histopathologic validation of lymph node staging with FDG-PET scan in cancer of the esophagus and gastroesophageal junction: A prospective study based on primary surgery with extensive lymphadenectomy. Ann Surg 2000 1.11
40 Current treatments and future perspectives in colorectal and gastric cancer. Ann Oncol 2003 1.11
41 Efficacy of capecitabine versus 5-fluorouracil in colorectal and gastric cancers: a meta-analysis of individual data from 6171 patients. Ann Oncol 2011 1.11
42 Bevacizumab plus chemotherapy continued beyond first progression in patients with metastatic colorectal cancer previously treated with bevacizumab plus chemotherapy: ML18147 study KRAS subgroup findings. Ann Oncol 2013 1.06
43 Final results from a randomized phase 3 study of FOLFIRI {+/-} panitumumab for second-line treatment of metastatic colorectal cancer. Ann Oncol 2014 1.03
44 Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer. Ann Oncol 2007 1.02
45 Toward optimized front-line therapeutic strategies in patients with metastatic colorectal cancer--an expert review from the International Congress on Anti-Cancer Treatment (ICACT) 2009. Ann Oncol 2010 1.01
46 Pancreatic cancer treatment and research: an international expert panel discussion. Ann Oncol 2011 1.01
47 The utility of positron emission tomography for the diagnosis and staging of recurrent esophageal cancer. J Thorac Cardiovasc Surg 2000 1.00
48 ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer. Tomudex Colorectal Study Group. J Clin Oncol 1996 1.00
49 Randomized phase III trials of adjuvant FAMTX or FEMTX compared with surgery alone in resected gastric cancer. A combined analysis of the EORTC GI Group and the ICCG. Ann Oncol 2005 1.00
50 Cediranib with mFOLFOX6 vs bevacizumab with mFOLFOX6 in previously treated metastatic colorectal cancer. Br J Cancer 2013 0.99
51 Docetaxel plus oxaliplatin with or without fluorouracil or capecitabine in metastatic or locally recurrent gastric cancer: a randomized phase II study. Ann Oncol 2015 0.97
52 Predictive factors of survival in patients with advanced colorectal cancer: an individual data analysis of 602 patients included in irinotecan phase III trials. Ann Oncol 2004 0.97
53 Size quantification of liver metastases in patients undergoing cancer treatment: reproducibility of one-, two-, and three-dimensional measurements determined with spiral CT. Radiology 1997 0.96
54 Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour). Br J Cancer 2001 0.94
55 A multi-center phase II study of BMS-247550 (Ixabepilone) by two schedules in patients with metastatic gastric adenocarcinoma previously treated with a taxane. Invest New Drugs 2006 0.94
56 Vinorelbine and cisplatin in metastatic squamous cell carcinoma of the oesophagus: response, toxicity, quality of life and survival. Ann Oncol 2002 0.94
57 The role of chemotherapy in biliary tract carcinoma. HPB (Oxford) 2008 0.93
58 EORTC Elderly Task Force experts' opinion for the treatment of colon cancer in older patients. Cancer Treat Rev 2009 0.93
59 Optimizing the use of irinotecan in colorectal cancer. Oncologist 2001 0.92
60 Incidence of cardiotoxicity with the oral fluoropyrimidine capecitabine is typical of that reported with 5-fluorouracil. Ann Oncol 2002 0.91
61 Clinical value of whole-body emission tomography in potentially curable colorectal liver metastases. Eur J Surg Oncol 2001 0.90
62 Phase II randomized, double-blind, placebo-controlled study of AMG 386 (trebananib) in combination with cisplatin and capecitabine in patients with metastatic gastro-oesophageal cancer. Ann Oncol 2012 0.90
63 New directions in the treatment of colorectal cancer: a look to the future. Eur J Cancer 2000 0.89
64 HIPEC in T4a colon cancer: a defendable treatment to improve oncologic outcome? Ann Oncol 2012 0.89
65 Effect of motilin on gastric emptying in patients with diabetic gastroparesis. Gastroenterology 1992 0.89
66 Intrinsic resistance to selumetinib, a selective inhibitor of MEK1/2, by cAMP-dependent protein kinase A activation in human lung and colorectal cancer cells. Br J Cancer 2012 0.88
67 Effects of preoperative chemoradiotherapy on postsurgical morbidity and mortality in cT3-4 +/- cM1lymph cancer of the oesophagus and gastro-oesophageal junction. Eur J Cardiothorac Surg 2003 0.87
68 Transcatheter embolization of hepatic arteriovenous fistulas in Rendu-Osler-Weber disease: a case report and review of the literature. Eur Radiol 1999 0.86
69 Irinotecan in second-line treatment of metastatic colorectal cancer: improved survival and cost-effect compared with infusional 5-FU. Eur J Cancer 1999 0.85
70 Surgery for gastric remnant carcinoma following Billroth II gastrectomy. Eur J Surg Oncol 1997 0.83
71 Reversal of hepatorenal syndrome in four patients by peroral misoprostol (prostaglandin E1 analogue) and albumin administration. J Hepatol 1990 0.83
72 Visualization and characterization of gastric contractions using a radionuclide technique. Am J Physiol 1990 0.83
73 Analysis of HER2 expression and gene amplification in adenocarcinoma of the stomach and the gastro-oesophageal junction: rationale for the Belgian way of working. Acta Gastroenterol Belg 2012 0.83
74 Quality assurance in colonoscopy for colorectal cancer diagnosis. Eur J Surg Oncol 2010 0.83
75 Effect of proximal vagotomy and Roux-en-Y diversion on gastric emptying kinetics in asymptomatic patients. Clin Nucl Med 1990 0.82
76 Toxicity of irinotecan in patients with colorectal cancer. N Engl J Med 2001 0.82
77 Combination of gemcitabine and cetuximab in patients with advanced cholangiocarcinoma: a phase II study of the Belgian Group of Digestive Oncology. Ann Oncol 2013 0.81
78 Reporting on the results of cancer treatment in patients with metastatic liver disease: proposal of symmetric size-dependent CT-criteria for response. Ann Oncol 1996 0.81
79 Mean overall survival gain with aflibercept plus FOLFIRI vs placebo plus FOLFIRI in patients with previously treated metastatic colorectal cancer. Br J Cancer 2013 0.81
80 Carcinoid heart disease--a hidden complication of neuroendocrine tumours. Acta Gastroenterol Belg 2009 0.81
81 Role of chemotherapy in gastro-entero-pancreatic neuroendocrine tumors: the end of a story? Acta Gastroenterol Belg 2009 0.79
82 The antiproliferative effect of somatostatin analogs: clinical relevance in patients with neuroendocrine gastro-entero-pancreatic tumours. Acta Gastroenterol Belg 2009 0.78
83 Cost-effectiveness of cetuximab in combination with irinotecan compared with current care in metastatic colorectal cancer after failure on irinotecan--a Belgian analysis. Acta Clin Belg 2008 0.78
84 The EORTC Gastrointestinal Tract Cancer Group: 40 years of research contributing to improved GI cancer management. Eur J Cancer 2002 0.78
85 Germline mutations of the hMLH1 and hMSH2 mismatch repair genes in Belgian hereditary nonpolyposis colon cancer (HNPCC) patients. Fam Cancer 2006 0.78
86 Position of positron emission tomography and other imaging diagnostic modalities in esophageal cancer. Q J Nucl Med Mol Imaging 2004 0.78
87 Induction therapy for clinical T4 oesophageal carcinoma; a plea for continued surgical exploration. Eur J Cardiothorac Surg 1997 0.78
88 Persisting anorectal dysfunction after rectal cancer surgery. Colorectal Dis 2013 0.77
89 Chemo-radiotherapy versus radiotherapy alone in the pre-operative treatment of resectable rectal cancer. Eur J Surg Oncol 2005 0.77
90 Quality of care indicators in rectal cancer. Acta Gastroenterol Belg 2011 0.77
91 The molecular basis of colorectal cancer. Acta Gastroenterol Belg 2001 0.77
92 Different gastritis features are linked to different gastric neoplasms. Gastroenterol Clin Biol 1999 0.77
93 Yield of routine imaging after curative colorectal cancer treatment. Acta Chir Belg 2008 0.76
94 Psychological implications of living with familial adenomatous polyposis. Acta Gastroenterol Belg 2011 0.76
95 The role of oxaliplatin in the management of upper gastrointestinal tract malignancies. Colorectal Dis 2003 0.76
96 Familial adenomatous polyposis: clinical presentation, detection and surveillance. Acta Gastroenterol Belg 2011 0.76
97 Different surgical strategies in the treatment of familial adenomatous polyposis: what's the role of the ileal pouch-anal anastomosis? Acta Gastroenterol Belg 2011 0.76
98 Computed tomographic colonography. Acta Gastroenterol Belg 2005 0.75
99 Malignant degeneration of esophageal squamous papilloma associated with the human papillomavirus. Gastroenterology 1992 0.75
100 Multicentre phase II pharmacokinetic and pharmacodynamic study of OSI-7904L in previously untreated patients with advanced gastric or gastroesophageal junction adenocarcinoma. Br J Cancer 2006 0.75
101 Report on the Belgian consensus meeting on colorectal cancer screening. Acta Gastroenterol Belg 2005 0.75
102 Quality assurance and recommendations for quality assessment of screening colonoscopy in Belgium. Acta Gastroenterol Belg 2009 0.75
103 Compassionate use of Gemzar in advanced pancreatic cancer: a Belgian experience. Acta Gastroenterol Belg 2002 0.75
104 Multiple brain abscesses caused by Torulopsis glabrata in an immunocompromised patient. Mykosen 1986 0.75
105 Medical care consumption in a phase III trial comparing irinotecan with infusional 5-fluorouracil (5-FU) in patients with metastatic colorectal cancer after 5-FU failure. Anticancer Drugs 1999 0.75
106 Clinical characteristics and management of insulin-producing neuroendocrine carcinomas. Acta Gastroenterol Belg 2016 0.75
107 Screening applications for MRI in the detection of upper abdominal disease: comparative study of non-contrast-enhanced single-shot MRI and contrast-enhanced helical CT. Eur Radiol 1999 0.75
108 Raltitrexed plus gemcitabine (TOMGEM) in advanced pancreatic cancer. Results of a Belgian multicentre phase II study. Oncology 2004 0.75
109 Intestinal metaplasia in gastric malignancy: a comparison between carcinoma and lymphoma. Eur J Gastroenterol Hepatol 1998 0.75
110 FAPA--familial adenomatous polyposis association the Belgian Polyposis Registry. Acta Gastroenterol Belg 2011 0.75
111 Lymphocytic meningitis: a review of the literature. Acta Clin Belg 1987 0.75
112 Malignant involvement of the knee synovium in a patient with metastastic oesophageal adenocarcinoma. Acta Clin Belg 2010 0.75
113 Treatment of a metastasis of a rectal carcinoma in the greater trochanter with the AO/ASIF Proximal Femoral Nail. A case report. Acta Chir Belg 2004 0.75
114 Radioimmunoguided surgery for colorectal carcinoma. Hepatogastroenterology 1999 0.75
115 A new imaging technique for colorectal cancer: positron emission tomography. Semin Oncol 2000 0.75
116 Cell kinetic measurements: principles, guidelines for treatment? Hepatogastroenterology 1999 0.75
117 Curative management of adenocarcinoma of the oesophagus and oesogastric junction--current recommendations of the Belgian Working Group. Acta Gastroenterol Belg 2001 0.75
118 Follow-up of colon cancer: detection of liver metastases: benefit and periodicity. Acta Gastroenterol Belg 1998 0.75
119 The potential role of targeted therapies in the management of neuroendocrine tumours. Acta Gastroenterol Belg 2009 0.75
120 Diagnostic pitfalls in digestive neuroendocrine tumours. Acta Gastroenterol Belg 2009 0.75