The 3R principle and the use of non-human primates in the study of neurodegenerative diseases: the case of Parkinson's disease.

PubWeight™: 0.82‹?›

🔗 View Article (PMID 18773919)

Published in Neurosci Biobehav Rev on August 19, 2008

Authors

Augusto Vitale1, Arianna Manciocco, Enrico Alleva

Author Affiliations

1: Section of Behavioural Neuroscience, Dipartimento di Biologia Cellulare e Neuroscienze, Istituto Superiore di Sanità, Viale Regina Elena, 299, Rome 00161, Italy. vitale@iss.it

Articles by these authors

Epigenetic modifications induced by early enrichment are associated with changes in timing of induction of BDNF expression. Neurosci Lett (2011) 1.62

Effects of perinatal exposure to a polybrominated diphenyl ether (PBDE 99) on mouse neurobehavioural development. Neurotoxicology (2002) 1.39

Early social enrichment shapes social behavior and nerve growth factor and brain-derived neurotrophic factor levels in the adult mouse brain. Biol Psychiatry (2006) 1.30

Polybrominated diphenyl ethers: neurobehavioral effects following developmental exposure. Neurotoxicology (2003) 1.25

Early life stress as a risk factor for mental health: role of neurotrophins from rodents to non-human primates. Neurosci Biobehav Rev (2008) 1.23

Transgenic mouse in vivo library of human Down syndrome critical region 1: association between DYRK1A overexpression, brain development abnormalities, and cell cycle protein alteration. J Neuropathol Exp Neurol (2004) 1.20

Rhes is involved in striatal function. Mol Cell Biol (2004) 1.17

Changes in plasma levels of BDNF and NGF reveal a gender-selective vulnerability to early adversity in rhesus macaques. Psychoneuroendocrinology (2008) 1.10

Early interactions with mother and peers independently build adult social skills and shape BDNF and oxytocin receptor brain levels. Psychoneuroendocrinology (2012) 1.05

A retrospective performance assessment of the developmental neurotoxicity study in support of OECD test guideline 426. Environ Health Perspect (2008) 1.05

Cephalopods in neuroscience: regulations, research and the 3Rs. Invert Neurosci (2014) 1.02

Early life influences on emotional reactivity: evidence that social enrichment has greater effects than handling on anxiety-like behaviors, neuroendocrine responses to stress and central BDNF levels. Neurosci Biobehav Rev (2010) 1.01

The NGF saga: from animal models of psychosocial stress to stress-related psychopathology. Front Neuroendocrinol (2009) 1.01

Role of neuroinflammation in hypertension-induced brain amyloid pathology. Neurobiol Aging (2010) 0.99

Early behavioural markers of disease in P301S tau transgenic mice. Behav Brain Res (2009) 0.99

Early exposure to low doses of atrazine affects behavior in juvenile and adult CD1 mice. Toxicology (2010) 0.98

Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice. Exp Gerontol (2006) 0.98

Intrahippocampal administration of BDNF in adult rats affects short-term behavioral plasticity in the Morris water maze and performance in the elevated plus-maze. Hippocampus (2004) 0.98

Early developmental exposure to BDE 99 or Aroclor 1254 affects neurobehavioural profile: interference from the administration route. Neurotoxicology (2005) 0.97

Early social enrichment augments adult hippocampal BDNF levels and survival of BrdU-positive cells while increasing anxiety- and "depression"-like behavior. J Neurosci Res (2006) 0.96

Use of assistance and therapy dogs for children with autism spectrum disorders: a critical review of the current evidence. J Altern Complement Med (2012) 0.96

The role of voluntary exercise in enriched rearing: a behavioral analysis. Behav Neurosci (2006) 0.95

Communal nesting, an early social enrichment, affects social competences but not learning and memory abilities at adulthood. Behav Brain Res (2007) 0.95

Neonatal behaviors associated with ultrasonic vocalizations in mice (mus musculus): A slow-motion analysis. Dev Psychobiol (2004) 0.94

Communal nesting, an early social enrichment, increases the adult anxiety-like response and shapes the role of social context in modulating the emotional behavior. Behav Brain Res (2006) 0.93

Nonmotor symptoms in Parkinson's disease: investigating early-phase onset of behavioral dysfunction in the 6-hydroxydopamine-lesioned rat model. J Neurosci Res (2008) 0.93

Animal-assisted interventions as innovative tools for mental health. Ann Ist Super Sanita (2011) 0.92

Social deprivation stress is a triggering factor for the emergence of anxiety- and depression-like behaviours and leads to reduced brain BDNF levels in C57BL/6J mice. Psychoneuroendocrinology (2011) 0.91

Antidepressant treatment outcome depends on the quality of the living environment: a pre-clinical investigation in mice. PLoS One (2013) 0.87

Altered emotionality, spatial memory and cholinergic function in caveolin-1 knock-out mice. Behav Brain Res (2007) 0.87

Shaping brain development: mouse communal nesting blunts adult neuroendocrine and behavioral response to social stress and modifies chronic antidepressant treatment outcome. Psychoneuroendocrinology (2009) 0.87

Early social enrichment provided by communal nest increases resilience to depression-like behavior more in female than in male mice. Behav Brain Res (2010) 0.84

Long-term effects of the periadolescent environment on exploratory activity and aggressive behaviour in mice: social versus physical enrichment. Physiol Behav (2004) 0.84

Birth spacing in the mouse communal nest shapes adult emotional and social behavior. Physiol Behav (2008) 0.84

A trouble shared is a trouble halved: social context and status affect pain in mouse dyads. PLoS One (2009) 0.83

The application of Russell and Burch 3R principle in rodent models of neurodegenerative disease: the case of Parkinson's disease. Neurosci Biobehav Rev (2008) 0.83

Not all stressors are equal: early social enrichment favors resilience to social but not physical stress in male mice. Horm Behav (2013) 0.83

Prolonged perinatal AZT administration and early maternal separation: effects on social and emotional behaviour of periadolescent mice. Pharmacol Biochem Behav (2003) 0.83

Evaluation of gene, protein and neurotrophin expression in the brain of mice exposed to space environment for 91 days. PLoS One (2012) 0.82

Early behavioural enrichment in the form of handling renders mouse pups unresponsive to anxiolytic drugs and increases NGF levels in the hippocampus. Behav Brain Res (2006) 0.82

Effects of spatial and cognitive enrichment on activity pattern and learning performance in three strains of mice in the IntelliMaze. Behav Genet (2011) 0.81

Striatal 6-OHDA lesion in mice: Investigating early neurochemical changes underlying Parkinson's disease. Behav Brain Res (2009) 0.81

Early handling increases susceptibility to experimental autoimmune encephalomyelitis (EAE) in C57BL/6 male mice. J Neuroimmunol (2009) 0.81

Fighting in the aged male mouse increases the expression of TrkA and TrkB in the subventricular zone and in the hippocampus. Behav Brain Res (2005) 0.81

Behavioral responses of 129/Sv, C57BL/6J and DBA/2J mice to a non-predator aversive olfactory stimulus. Acta Neurobiol Exp (Wars) (2005) 0.80

A novel BDNF polymorphism affects plasma protein levels in interaction with early adversity in rhesus macaques. Psychoneuroendocrinology (2010) 0.80

Acute global anoxia during C-section birth affects dopamine-mediated behavioural responses and reactivity to stress. Behav Brain Res (2004) 0.80

Response to novelty, social and self-control behaviors, in rats exposed to neonatal anoxia: modulatory effects of an enriched environment. Psychopharmacology (Berl) (2005) 0.80

Agonistic encounters in aged male mouse potentiate the expression of endogenous brain NGF and BDNF: possible implication for brain progenitor cells' activation. Eur J Neurosci (2003) 0.80

Bird populations as sentinels of endocrine disrupting chemicals. Ann Ist Super Sanita (2010) 0.80

Animal models of anti-HIV drugs exposure during pregnancy: effects on neurobehavioral development. Prog Neuropsychopharmacol Biol Psychiatry (2002) 0.80

Scopolamine effects on ultrasonic vocalization emission and behavior in the neonatal mouse. Behav Brain Res (2004) 0.80

Developing effective animal-assisted intervention programs involving visiting dogs for institutionalized geriatric patients: a pilot study. Psychogeriatrics (2012) 0.79

Individual differences in choice (in)flexibility but not impulsivity in the common marmoset: an automated, operant-behavior choice task. Behav Brain Res (2013) 0.79

NGF, brain and behavioral plasticity. Neural Plast (2012) 0.79

Quality and timing of stressors differentially impact on brain plasticity and neuroendocrine-immune function in mice. Neural Plast (2013) 0.79

Monomorphic region of the serotonin transporter promoter gene in New World monkeys. Am J Primatol (2012) 0.79

Short-term hypergravity influences NGF and BDNF expression, and mast cell distribution in the lungs and heart of adult male mice. J Gravit Physiol (2002) 0.79

Cognitive and emotional alterations in periadolescent mice exposed to 2 g hypergravity field. Physiol Behav (2004) 0.78

Effects of maternal L-tryptophan depletion and corticosterone administration on neurobehavioral adjustments in mouse dams and their adolescent and adult daughters. Prog Neuropsychopharmacol Biol Psychiatry (2011) 0.78

Assessing the interplay between fear and learning in mice exposed to a live rat in a spatial memory task (MWM). Anim Cogn (2008) 0.77

Neurobehavioural responses to hypergravity environment in the CD-1 mouse. J Gravit Physiol (2002) 0.77

Daily serum and salivary BDNF levels correlate with morning-evening personality type in women and are affected by light therapy. Riv Psichiatr (2012) 0.77

The richness of social stimuli shapes developmental trajectories: Are laboratory mouse pups impoverished? Prog Neuropsychopharmacol Biol Psychiatry (2011) 0.77

Prolonged prenatal exposure to low-level ozone affects aggressive behaviour as well as NGF and BDNF levels in the central nervous system of CD-1 mice. Behav Brain Res (2005) 0.77

Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice. Exp Gerontol (2010) 0.77

A mouse model of neurobehavioural response to altered gravity conditions: an ontogenetical study. Behav Brain Res (2008) 0.76

Analysis of ultrasonic vocalizations emitted by infant rodents. Curr Protoc Toxicol (2006) 0.76

Repeated acute exposures to hypergravity during early development subtly affect CD-1 mouse neurobehavioural profile. Brain Res Bull (2006) 0.76

Sustained hippocampal neurogenesis in females is amplified in P66(Shc-/-) mice: An animal model of healthy aging. Hippocampus (2012) 0.76

Exchanging grooming, but not tolerance and aggression in common marmosets (Callithrix jacchus). Am J Primatol (2014) 0.76

Efficient testing strategies for evaluation of xenobiotics with neuroendocrine activity. Reprod Toxicol (2006) 0.76

Human mate preference: inconsistency between data and interpretations. Trends Ecol Evol (2010) 0.75

A new easy accessible and low-cost method for screening olfactory sensitivity in mice: behavioural and nociceptive response in male and female CD-1 mice upon exposure to millipede aversive odour. Brain Res Bull (2002) 0.75

Coma and vegetative states: state of the art and proposal of a novel approach combining existing coma scales. Ann Ist Super Sanita (2014) 0.75

Taking into account animal and human personalities: relevance for health and disease. Ann Ist Super Sanita (2011) 0.75

Editorial. Ann Ist Super Sanita (2009) 0.75

The use of common swift (Apus apus), an aerial feeder bird, as a bioindicator of persistent organic microcontaminants. Ann Ist Super Sanita (2008) 0.75

Issues raised by "incidental findings" and their ethical implications. Ann Ist Super Sanita (2013) 0.75

Conjunctivally administered NGF antibody reduces pain sensitivity and anxiety-like behavioral responses in aged female mice. Behav Brain Res (2010) 0.75

Incidental findings, genetic screening and the challenge of personalisation. Ann Ist Super Sanita (2014) 0.75

Effects of acute hypergravity exposure and parity on maternal behavior in CD-1 mice. Acta Neurobiol Exp (Wars) (2005) 0.75

Preface. Main health issues in the last decade. Ann Ist Super Sanita (2007) 0.75

Neurobehavioral coping to altered gravity: endogenous responses of neurotrophins. Prog Brain Res (2004) 0.75

Acute perinatal asphyxia at birth has long-term effects on behavioural arousal and maternal behaviour in lactating rats. Behav Brain Res (2006) 0.75

Behavioural genetics of Italians? Editorial. Ann Ist Super Sanita (2010) 0.75

A busy time for science editors. Ann Ist Super Sanita (2013) 0.75

Overview of behavioral teratology. Curr Protoc Toxicol (2005) 0.75

Environmental enrichment techniques in non-human primates. The case of Callitrichids. Ann Ist Super Sanita (2004) 0.75

Humans as donors and producers of biological material: some ethical considerations on a thin red line. Ann Ist Super Sanita (2013) 0.75