PubRank

Sandra L Siedlak

Author PubWeight™ 63.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc Natl Acad Sci U S A 2008 3.68
2 Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence. Biochemistry 2003 1.89
3 Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. Am J Pathol 2003 1.66
4 Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem 2005 1.61
5 Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis 2010 1.54
6 Chitin-like polysaccharides in Alzheimer's disease brains. Curr Alzheimer Res 2005 1.51
7 Vascular oxidative stress in Alzheimer disease. J Neurol Sci 2007 1.25
8 Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans. Neurosci Lett 2002 1.20
9 Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol 2007 1.18
10 LRRK2 protein is a component of Lewy bodies. Ann Neurol 2006 1.16
11 Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy 2007 1.14
12 Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. J Alzheimers Dis 2009 1.13
13 High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal. J Biol Chem 2001 1.07
14 Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure. PLoS One 2009 1.04
15 c-Jun phosphorylation in Alzheimer disease. J Neurosci Res 2007 1.03
16 Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis. J Neurochem 2008 1.03
17 Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging (Albany NY) 2009 1.01
18 Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material. J Alzheimers Dis 2008 1.00
19 LRRK2 in Parkinson's disease and dementia with Lewy bodies. Mol Neurodegener 2006 1.00
20 Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance. J Neurochem 2013 1.00
21 Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotox Res 2006 1.00
22 Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes. Age (Dordr) 2008 0.98
23 Distribution, levels, and activation of MEK1 in Alzheimer's disease. J Neurochem 2003 0.98
24 Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radic Biol Med 2005 0.98
25 Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathol 2005 0.98
26 Oxidative damage to nucleic acids in human prion disease. Neurobiol Dis 2002 0.96
27 Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Rep 2010 0.96
28 Neuroprotective properties of Bcl-w in Alzheimer disease. J Neurochem 2004 0.96
29 Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Mol Neurodegener 2009 0.95
30 A metabolic basis for Alzheimer disease. Neurochem Res 2003 0.94
31 Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice. Neurol Res 2003 0.94
32 A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules. Lab Invest 2011 0.91
33 Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer's brain. J Neuroinflammation 2013 0.90
34 Compensatory responses induced by oxidative stress in Alzheimer disease. Biol Res 2006 0.89
35 Bivalent ligand containing curcumin and cholesterol as fluorescence probe for Aβ plaques in Alzheimer's disease. ACS Chem Neurosci 2011 0.89
36 Oxidative damage is present in the fatal brain edema of diabetic ketoacidosis. Brain Res 2010 0.89
37 Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. Mol Neurodegener 2007 0.88
38 Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study. Exp Gerontol 2009 0.88
39 Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease. Int J Clin Exp Pathol 2008 0.87
40 Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radic Biol Med 2011 0.87
41 Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice. Ann N Y Acad Sci 2002 0.87
42 Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease. Biometals 2003 0.87
43 Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy? Alzheimers Dement 2006 0.87
44 Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease. J Neurochem 2006 0.84
45 Frontiers in Alzheimer's disease therapeutics. Ther Adv Chronic Dis 2011 0.84
46 A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. PLoS One 2010 0.84
47 Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies. Neurodegener Dis 2008 0.84
48 Redox active iron accumulation in aceruloplasminemia. Neuropathology 2008 0.84
49 Soluble amyloid beta-protein is increased in frontotemporal dementia with tau gene mutations. J Alzheimers Dis 2004 0.83
50 Mislocalization of CDK11/PITSLRE, a regulator of the G2/M phase of the cell cycle, in Alzheimer disease. Cell Mol Biol Lett 2011 0.82
51 The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau. Neurobiol Aging 2002 0.82
52 Indices of metabolic dysfunction and oxidative stress. Neurochem Res 2007 0.82
53 Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology 2010 0.81
54 The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies. J Neuropathol Exp Neurol 2011 0.80
55 The X-chromosome instability phenotype in Alzheimer's disease: a clinical sign of accelerating aging? Med Hypotheses 2009 0.80
56 Mathematical modeling of microtubule dynamics: insights into physiology and disease. Prog Neurobiol 2010 0.79
57 DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division. Neurodegener Dis 2013 0.78
58 Premature centromere division of metaphase chromosomes in peripheral blood lymphocytes of Alzheimer's disease patients: relation to gender and age. J Gerontol A Biol Sci Med Sci 2010 0.77
59 Tau modifiers as therapeutic targets for Alzheimer's disease. Biochim Biophys Acta 2005 0.76
60 Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease. J Neurosci Methods 2010 0.76
61 Accumulation of intraneuronal amyloid-β is common in normal brain. Curr Alzheimer Res 2014 0.76
62 Correction: Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation. PLoS One 2016 0.75
63 Natural oxidant balance in Parkinson disease. Arch Neurol 2009 0.75