PubRank

Antoni Camins

Author PubWeight™ 81.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations. Lancet Neurol 2011 1.27
2 Resveratrol and neurodegenerative diseases: activation of SIRT1 as the potential pathway towards neuroprotection. Curr Neurovasc Res 2009 1.20
3 Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs. Bioorg Med Chem 2008 1.14
4 From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). J Alzheimers Dis 2008 1.04
5 Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. J Med Chem 2008 1.03
6 Role of cell cycle re-entry in neurons: a common apoptotic mechanism of neuronal cell death. Neurotox Res 2011 1.01
7 Aging biology: a new frontier for drug discovery. Expert Opin Drug Discov 2012 1.01
8 Early amyloid accumulation in the hippocampus of SAMP8 mice. J Alzheimers Dis 2010 1.00
9 Neurotoxicity of amphetamine derivatives is mediated by caspase pathway activation in rat cerebellar granule cells. Toxicol Appl Pharmacol 2004 0.99
10 Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease. Neurobiol Aging 2011 0.96
11 Dietary resveratrol prevents Alzheimer's markers and increases life span in SAMP8. Age (Dordr) 2012 0.96
12 Neurophysiological and epigenetic effects of physical exercise on the aging process. Ageing Res Rev 2011 0.95
13 Kainic acid-induced apoptosis in cerebellar granule neurons: an attempt at cell cycle re-entry. Neuroreport 2002 0.92
14 Inhibition of cell cycle pathway by flavopiridol promotes survival of cerebellar granule cells after an excitotoxic treatment. J Pharmacol Exp Ther 2003 0.92
15 Increased permeability of blood-brain barrier on the hippocampus of a murine model of senescence. Mech Ageing Dev 2007 0.91
16 Modulation of sirtuins: new targets for antiageing. Recent Pat CNS Drug Discov 2008 0.91
17 Differences in activation of ERK1/2 and p38 kinase in Jnk3 null mice following KA treatment. J Neurochem 2010 0.90
18 Inhibition of the cdk5/p25 fragment formation may explain the antiapoptotic effects of melatonin in an experimental model of Parkinson's disease. J Pineal Res 2006 0.90
19 Activation of the calpain/cdk5/p25 pathway in the girus cinguli in Parkinson's disease. Parkinsonism Relat Disord 2007 0.89
20 A molecular study of pathways involved in the inhibition of cell proliferation in neuroblastoma B65 cells by the GSK-3 inhibitors lithium and SB-415286. J Cell Mol Med 2008 0.89
21 A new method for determining blood-brain barrier integrity based on intracardiac perfusion of an Evans Blue-Hoechst cocktail. J Neurosci Methods 2008 0.89
22 Oxidative stress-induced DNA damage and cell cycle regulation in B65 dopaminergic cell line. Free Radic Res 2009 0.88
23 Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM). Mech Ageing Dev 2005 0.88
24 Cerebral amyloid angiopathy, blood-brain barrier disruption and amyloid accumulation in SAMP8 mice. Neurodegener Dis 2011 0.88
25 Evaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model. J Pineal Res 2008 0.88
26 Implication of the transcription factor E2F-1 in the modulation of neuronal apoptosis. Biomed Pharmacother 2006 0.87
27 Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease. Int J Clin Exp Pathol 2008 0.87
28 Characterization of amyloid-β granules in the hippocampus of SAMP8 mice. J Alzheimers Dis 2011 0.87
29 Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity. Free Radic Biol Med 2005 0.87
30 Molecular and biochemical features in Alzheimer's disease. Curr Pharm Des 2006 0.86
31 Peroxisome proliferator-activated receptor alpha down-regulation is associated with enhanced ceramide levels in age-associated cardiac hypertrophy. J Gerontol A Biol Sci Med Sci 2007 0.84
32 Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid. Int J Dev Neurosci 2008 0.84
33 PGC-1beta down-regulation is associated with reduced ERRalpha activity and MCAD expression in skeletal muscle of senescence-accelerated mice. J Gerontol A Biol Sci Med Sci 2006 0.84
34 PI3 k/akt inhibition induces apoptosis through p38 activation in neurons. Pharmacol Res 2013 0.84
35 Dendritic spine abnormalities in hippocampal CA1 pyramidal neurons underlying memory deficits in the SAMP8 mouse model of Alzheimer's disease. J Alzheimers Dis 2012 0.84
36 Antiapoptotic drugs: a therapautic strategy for the prevention of neurodegenerative diseases. Curr Pharm Des 2011 0.84
37 Activation of Akt by lithium: pro-survival pathways in aging. Mech Ageing Dev 2009 0.84
38 Study of the transcytosis of an anti-transferrin receptor antibody with a Fab' cargo across the blood-brain barrier in mice. Eur J Pharm Sci 2013 0.83
39 Lithium treatment decreases activities of tau kinases in a murine model of senescence. J Neuropathol Exp Neurol 2008 0.83
40 The antiproliferative activity of melatonin in B65 rat dopaminergic neuroblastoma cells is related to the downregulation of cell cycle-related genes. J Pineal Res 2008 0.83
41 Presence of a neo-epitope and absence of amyloid beta and tau protein in degenerative hippocampal granules of aged mice. Age (Dordr) 2013 0.83
42 Inhibition of CDKs: a strategy for preventing kainic acid-induced apoptosis in neurons. Ann N Y Acad Sci 2003 0.83
43 Kainic acid-induced neuronal cell death in cerebellar granule cells is not prevented by caspase inhibitors. Br J Pharmacol 2002 0.83
44 The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival. Brain Res 2008 0.82
45 Resveratrol inhibits proliferation and promotes apoptosis of neuroblastoma cells: role of sirtuin 1. Neurochem Res 2010 0.82
46 The p38(MAPK) signaling pathway regulates neuronal apoptosis through the phosphorylation of the retinoblastoma protein. Neurochem Int 2008 0.82
47 Dysfunction of astrocytes in senescence-accelerated mice SAMP8 reduces their neuroprotective capacity. Aging Cell 2008 0.82
48 Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8. Exp Gerontol 2006 0.82
49 Content and traffic of taurine in hippocampal reactive astrocytes. Hippocampus 2011 0.82
50 3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum. Neurosci Lett 2007 0.82
51 DNA low-density array analysis of colchicine neurotoxicity in rat cerebellar granular neurons. Neurotoxicology 2007 0.81
52 Neuroprotective and anti-ageing role of leptin. J Mol Endocrinol 2012 0.81
53 Neuroprotection associated with alternative splicing of NMDA receptors in rat cortical neurons. Br J Pharmacol 2006 0.81
54 Blood-brain barrier disruption in the striatum of rats treated with 3-nitropropionic acid. Neurotoxicology 2008 0.81
55 Different capacities of various NMDA receptor antagonists to prevent ischemia-induced neurodegeneration in human cultured NT2 neurons. Neurochem Int 2006 0.81
56 Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis. Neuropharmacology 2003 0.81
57 Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates. ChemMedChem 2010 0.80
58 Antiapoptotic effects of roscovitine in cerebellar granule cells deprived of serum and potassium: a cell cycle-related mechanism. Neurochem Int 2004 0.80
59 Effects of MPP+ on the molecular pathways involved in cell cycle control in B65 neuroblastoma cells. Pharmacol Res 2010 0.80
60 Physiological and behavioural consequences of long-term moderate treadmill exercise. Psychoneuroendocrinology 2012 0.80
61 GSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons. Pharmacol Res 2011 0.80
62 Neuronal cell cycle re-entry markers are altered in the senescence accelerated mouse P8 (SAMP8). J Alzheimers Dis 2012 0.80
63 Antiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells. Apoptosis 2011 0.80
64 Clustered granules present in the hippocampus of aged mice result from a degenerative process affecting astrocytes and their surrounding neuropil. Age (Dordr) 2014 0.80
65 Evaluation of the neuronal apoptotic pathways involved in cytoskeletal disruption-induced apoptosis. Biochem Pharmacol 2005 0.80
66 Resveratrol induces nuclear factor-κB activity in human cardiac cells. Int J Cardiol 2012 0.79
67 Systemic administration of 3-nitropropionic acid points out a different role for active caspase-3 in neurons and astrocytes. Neurochem Int 2009 0.79
68 Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol. J Pineal Res 2011 0.79
69 New oxapolycyclic cage amines with NMDA receptor antagonist and trypanocidal activities. Bioorg Med Chem 2009 0.79
70 Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice. Biochim Biophys Acta 2013 0.78
71 Inhibition of the cdk5/MEF2 pathway is involved in the antiapoptotic properties of calpain inhibitors in cerebellar neurons. Br J Pharmacol 2005 0.78
72 Prosurvival role of JAK/STAT and Akt signaling pathways in MPP+-induced apoptosis in neurons. Neurochem Int 2010 0.78
73 Neuroprotective effects of (+/-)-huprine Y on in vitro and in vivo models of excitoxicity damage. Exp Neurol 2003 0.78
74 Mavoglurant as a treatment for Parkinson's disease. Expert Opin Investig Drugs 2014 0.78
75 Evaluation of transcriptional activity of caspase-3 gene as a marker of acute neurotoxicity in rat cerebellar granular cells. Toxicol In Vitro 2009 0.78
76 Kainate-induced toxicity in the hippocampus: potential role of lithium. Bipolar Disord 2010 0.78
77 Evaluation of hypoxia inducible factor expression in inflammatory and neurodegenerative brain models. Int J Biochem Cell Biol 2013 0.78
78 Hypertriglyceridemia and hepatic steatosis in senescence-accelerated mouse associate to changes in lipid-related gene expression. J Gerontol A Biol Sci Med Sci 2007 0.78
79 Masitinib for the treatment of mild to moderate Alzheimer's disease. Expert Rev Neurother 2015 0.78
80 Evaluation of neuronal cell death by laser scanning cytometry. Brain Res Brain Res Protoc 2002 0.77
81 Neuroprotective effects of SB-415286 on hydrogen peroxide-induced cell death in B65 rat neuroblastoma cells and neurons. Int J Dev Neurosci 2008 0.77
82 Microarray analysis of rat hippocampus exposed to excitotoxicity: reversal Na(+)/Ca(2+) exchanger NCX3 is overexpressed in glial cells. Hippocampus 2010 0.77
83 Carnosine prevents methamphetamine-induced gliosis but not dopamine terminal loss in rats. Eur J Pharmacol 2002 0.77
84 Neuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the Atm/p53/E2F-1 path in cerebellar granule neurons. J Neurosci Res 2007 0.77
85 Evaluation of pathways involved in pentachlorophenol-induced apoptosis in rat neurons. Neurotoxicology 2009 0.77
86 GSK-3 beta inhibition and prevention of mitochondrial apoptosis inducing factor release are not involved in the antioxidant properties of SB-415286. Eur J Pharmacol 2008 0.76
87 Mice Lacking Functional Fas Death Receptors Are Protected from Kainic Acid-Induced Apoptosis in the Hippocampus. Mol Neurobiol 2014 0.76
88 A single dose of pirfenidone attenuates neuronal loss and reduces lipid peroxidation after kainic acid-induced excitotoxicity in the pubescent rat hippocampus. J Mol Neurosci 2013 0.76
89 P38 MAPK inhibition protects against glutamate neurotoxicity and modifies NMDA and AMPA receptor subunit expression. J Mol Neurosci 2014 0.76
90 Gene expression profile in JNK3 null mice: a novel specific activation of the PI3K/AKT pathway. J Neurochem 2011 0.76
91 Inhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons. J Mol Neurosci 2005 0.76
92 p21(WAF1/Cip1) is not involved in kainic acid-induced apoptosis in murine cerebellar granule cells. Brain Res 2004 0.76
93 Chronic administration of melatonin reduces cerebral injury biomarkers in SAMP8. J Pineal Res 2007 0.76
94 Cyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons. Br J Pharmacol 2004 0.75
95 Hepatic gene expression changes in an experimental model of accelerated senescence: the SAM-P8 mouse. J Gerontol A Biol Sci Med Sci 2008 0.75
96 Receptor to glutamate NMDA-type: the functional diversity of the nr1 isoforms and pharmacological properties. Curr Pharm Des 2013 0.75
97 Time-course of blood-brain barrier disruption in senescence-accelerated mouse prone 8 (SAMP8) mice. Int J Dev Neurosci 2008 0.75
98 Metabolic basis of sporadic Alzeimer's disease. role of hormones related to energy metabolism. Curr Pharm Des 2013 0.75
99 Pirfenidone Attenuates Microglial Reactivity and Reduces Inducible Nitric Oxide Synthase mRNA Expression After Kainic Acid-Mediated Excitotoxicity in Pubescent Rat Hippocampus. J Mol Neurosci 2015 0.75
100 Synthesis, uptake and release of taurine in astrocytes treated with 8-Br-cAMP. Neurosci Lett 2009 0.75
101 ATM is involved in cell-cycle control through the regulation of retinoblastoma protein phosphorylation. J Cell Biochem 2010 0.75
102 Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid. J Neurosci Res 2012 0.75
103 Flow cytometric determination of cytoplasmic oxidants and mitochondrial membrane potential in neuronal cells. Methods Enzymol 2002 0.75
104 Tau hyperphosphorylation and axonal damage induced by N,N-diethyldithiocarbamate (DEDTC) treatment along late postnatal development is followed by a rescue during adulthood. J Neurosci Res 2010 0.75
105 Study of the pathways involved in apoptosis induced by PI3K inhibition in cerebellar granule neurons. Neurochem Int 2011 0.75
106 Neuronal apoptosis in the striatum of rats treated with 3-nitropropionic acid is not triggered by cell-cycle re-entry. Neurotoxicology 2011 0.75