Published in J Med Chem on September 12, 2008
A novel facile method of labeling octreotide with (18)F-fluorine. J Nucl Med (2010) 1.47
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Growing applications of "click chemistry" for bioconjugation in contemporary biomedical research. Cancer Biother Radiopharm (2009) 1.30
Efficient (18)F-labeling of large 37-amino-acid pHLIP peptide analogues and their biological evaluation. Bioconjug Chem (2012) 1.23
The growing impact of bioorthogonal click chemistry on the development of radiopharmaceuticals. J Nucl Med (2013) 1.22
Tumor Targeting via Integrin Ligands. Front Oncol (2013) 1.15
Rapid and simple one-step F-18 labeling of peptides. Bioconjug Chem (2011) 1.06
Design and development of molecular imaging probes. Curr Top Med Chem (2010) 1.02
Preparation of 18F-labeled peptides using the copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition. Nat Protoc (2011) 0.97
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Evaluation of [64Cu]Cu-DOTA and [64Cu]Cu-CB-TE2A chelates for targeted positron emission tomography with an alphavbeta6-specific peptide. Mol Imaging (2009) 0.95
Optimized labeling of NOTA-conjugated octreotide with F-18. Tumour Biol (2011) 0.95
Copper-Free Click for PET: Rapid 1,3-Dipolar Cycloadditions with a Fluorine-18 Cyclooctyne. ACS Med Chem Lett (2011) 0.91
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Radiolabeled Cyclic RGD Peptide Bioconjugates as Radiotracers Targeting Multiple Integrins. Bioconjug Chem (2015) 0.86
18F-labeling using click cycloadditions. Biomed Res Int (2014) 0.83
Click chemistry in peptide-based drug design. Molecules (2013) 0.82
Characterization and evaluation of (64)Cu-labeled A20FMDV2 conjugates for imaging the integrin αvβ 6. Mol Imaging Biol (2014) 0.77
Molecular imaging of integrin αvβ6 expression in living subjects. Am J Nucl Med Mol Imaging (2014) 0.77
Fluorinated ΔF508-CFTR correctors and potentiators for PET imaging. Bioorg Med Chem Lett (2012) 0.75
A One-Pot Three-Component Double-Click Method for Synthesis of [(67)Cu]-Labeled Biomolecular Radiotherapeutics. Sci Rep (2017) 0.75
Radiolabeled cyclic RGD peptides as radiotracers for tumor imaging. Biophys Rep (2016) 0.75
Solid-phase synthesis and fluorine-18 radiolabeling of cycloRGDyK. Org Biomol Chem (2016) 0.75
Click Chemistry: Diverse Chemical Function from a Few Good Reactions. Angew Chem Int Ed Engl (2001) 19.25
The growing impact of click chemistry on drug discovery. Drug Discov Today (2003) 6.79
The 2006 Henry N. Wagner Lecture: Of mice and men (and positrons)--advances in PET imaging technology. J Nucl Med (2006) 2.65
Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma. J Clin Invest (2005) 2.61
[18F]Galacto-RGD: synthesis, radiolabeling, metabolic stability, and radiation dose estimates. Bioconjug Chem (2004) 2.20
Two-step methodology for high-yield routine radiohalogenation of peptides: (18)F-labeled RGD and octreotide analogs. J Nucl Med (2004) 2.14
18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis. Nucl Med Biol (2004) 1.99
Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction. J Biol Chem (1990) 1.76
Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism. Cancer Res (2008) 1.73
Click chemistry for (18)F-labeling of RGD peptides and microPET imaging of tumor integrin alphavbeta3 expression. Bioconjug Chem (2007) 1.64
"Click labeling" with 2-[18f]fluoroethylazide for positron emission tomography. Bioconjug Chem (2007) 1.61
Overexpression of the alpha v beta 6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival. J Pathol (2007) 1.60
A comparative study of N.C.A. fluorine-18 labeling of proteins via acylation and photochemical conjugation. Nucl Med Biol (1996) 1.40
A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer. Cancer Res (2007) 1.39
Peptide-based radiopharmaceuticals: future tools for diagnostic imaging of cancers and other diseases. Med Res Rev (2004) 1.20
Structure-function analysis of Arg-Gly-Asp helix motifs in alpha v beta 6 integrin ligands. J Biol Chem (2007) 1.18
Radiolabelling of isopeptide N epsilon-(gamma-glutamyl)-L-lysine by conjugation with N-succinimidyl-4-[18F]fluorobenzoate. Appl Radiat Isot (2003) 1.10
18F-labeled insulin: a prosthetic group methodology for incorporation of a positron emitter into peptides and proteins. Biochemistry (1989) 1.03
Fully automated preparation of n.c.a. 4-[18F]fluorobenzoic acid and N-succinimidyl 4-[18F]fluorobenzoate using a Siemens/CTI chemistry process control unit (CPCU). Appl Radiat Isot (2006) 1.01
(2-[18F]fluoropropionyl-(D)phe1)-octreotide, a potential radiopharmaceutical for quantitative somatostatin receptor imaging with PET: synthesis, radiolabeling, in vitro validation and biodistribution in mice. Nucl Med Biol (1994) 0.99
Rapid solid phase synthesis and biodistribution of 18F-labelled linear peptides. Eur J Nucl Med Mol Imaging (2002) 0.98
Comparison of an 18F labeled derivative of vasoactive intestinal peptide and 2-deoxy-2-[18F]fluoro-D-glucose in nude mice bearing breast cancer xenografts. Mol Imaging Biol (2002) 0.91
Chemoselective hydrazone formation between HYNIC-functionalized peptides and (18)F-fluorinated aldehydes. Nucl Med Biol (2006) 0.90
Solid-phase synthesis of 2-[18F]fluoropropionyl peptides. Bioconjug Chem (2006) 0.89
18F-fluorothiols: a new approach to label peptides chemoselectively as potential tracers for positron emission tomography. Bioconjug Chem (2004) 0.84
Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging. Nat Chem Biol (2006) 3.22
The minimum element of a synthetic peptide required to block prostate tumor cell migration. Cancer Biol Ther (2006) 2.20
From combinatorial chemistry to cancer-targeting peptides. Mol Pharm (2007) 1.98
A novel peptide-based encoding system for "one-bead one-compound" peptidomimetic and small molecule combinatorial libraries. J Am Chem Soc (2002) 1.87
Long-circulating liposomes radiolabeled with [18F]fluorodipalmitin ([18F]FDP). Nucl Med Biol (2007) 1.60
Enhanced tumor retention of a radiohalogen label for site-specific modification of antibodies. J Med Chem (2013) 1.49
Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. J Immunol (2005) 1.47
Site-specifically 89Zr-labeled monoclonal antibodies for ImmunoPET. Nucl Med Biol (2010) 1.38
Structure-function analysis of Arg-Gly-Asp helix motifs in alpha v beta 6 integrin ligands. J Biol Chem (2007) 1.18
Dynamic microPET imaging of ultrasound contrast agents and lipid delivery. J Control Release (2008) 1.16
Identification of novel targeting peptides for human ovarian cancer cells using "one-bead one-compound" combinatorial libraries. Mol Cancer Ther (2005) 1.16
Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor model. Cancer Res (2009) 1.14
Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method. J Med Chem (2009) 1.10
High-throughput in vivo screening of targeted molecular imaging agents. Proc Natl Acad Sci U S A (2009) 1.05
Near-infrared optical imaging of ovarian cancer xenografts with novel alpha 3-integrin binding peptide "OA02". Mol Imaging (2005) 1.04
Dynamic imaging of arginine-rich heart-targeted vehicles in a mouse model. Biomaterials (2008) 1.03
Fully automated preparation of n.c.a. 4-[18F]fluorobenzoic acid and N-succinimidyl 4-[18F]fluorobenzoate using a Siemens/CTI chemistry process control unit (CPCU). Appl Radiat Isot (2006) 1.01
Preoperative evaluation of pancreatic adenocarcinoma. J Hepatobiliary Pancreat Surg (2008) 1.00
111In-LLP2A-DOTA Polyethylene Glycol-Targeting {alpha}4{beta}1 Integrin: Comparative Pharmacokinetics for Imaging and Therapy of Lymphoid Malignancies. J Nucl Med (2009) 0.98
Radiolabeling rhesus monkey CD34+ hematopoietic and mesenchymal stem cells with 64Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for microPET imaging. Mol Imaging (2008) 0.97
A modular platform for the rapid site-specific radiolabeling of proteins with 18F exemplified by quantitative positron emission tomography of human epidermal growth factor receptor 2. J Med Chem (2009) 0.97
Preparation of 18F-labeled peptides using the copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition. Nat Protoc (2011) 0.97
The development of peptide-based tools for the analysis of angiogenesis. Chem Biol (2011) 0.97
Evaluation of [64Cu]Cu-DOTA and [64Cu]Cu-CB-TE2A chelates for targeted positron emission tomography with an alphavbeta6-specific peptide. Mol Imaging (2009) 0.95
Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice. Proc Natl Acad Sci U S A (2011) 0.95
Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible. J Immunol (2004) 0.92
In vivo tracking of Th1 cells by PET reveals quantitative and temporal distribution and specific homing in lymphatic tissue. J Nucl Med (2014) 0.90
Evaluation of an integrin αvβ6-specific peptide labeled with [18F]fluorine by copper-free, strain-promoted click chemistry. Nucl Med Biol (2012) 0.90
Solid-phase synthesis of 2-[18F]fluoropropionyl peptides. Bioconjug Chem (2006) 0.89
Immuno-PET of the hepatocyte growth factor receptor Met using the 1-armed antibody onartuzumab. J Nucl Med (2012) 0.89
Microfluidic system for facilitated quantification of nanoparticle accumulation to cells under laminar flow. Ann Biomed Eng (2012) 0.85
Development and evaluation of a novel method for preclinical measurement of tissue vascular volume. Mol Pharm (2010) 0.85
Peptide ligands targeting integrin alpha3beta1 in non-small cell lung cancer. Lung Cancer (2006) 0.83
Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells. Mol Cancer Ther (2004) 0.83
In vitro and in vivo evaluation of the effects of aluminum [¹⁸F]fluoride radiolabeling on an integrin αvβ₆-specific peptide. Nucl Med Biol (2013) 0.83
Imaging and pharmacokinetics of (64)Cu-DOTA-HB22.7 administered by intravenous, intraperitoneal, or subcutaneous injection to mice bearing non-Hodgkin's lymphoma xenografts. Mol Imaging Biol (2008) 0.82
Photolabile micropatterned surfaces for cell capture and release. Chem Commun (Camb) (2011) 0.82
ImmunoPET imaging of phosphatidylserine in pro-apoptotic therapy treated tumor models. Nucl Med Biol (2012) 0.81
A physiological perspective on the use of imaging to assess the in vivo delivery of therapeutics. Ann Biomed Eng (2013) 0.79
Cerenkov luminescence imaging of αv β6 integrin expressing tumors using (90) Y-labeled peptides. J Labelled Comp Radiopharm (2014) 0.78
Nanomedicine explored at molecular imaging summit. Mol Imaging (2011) 0.78
Characterization and evaluation of (64)Cu-labeled A20FMDV2 conjugates for imaging the integrin αvβ 6. Mol Imaging Biol (2014) 0.77
Optimization of the solid-phase synthesis of [18F] radiolabeled peptides for positron emission tomography. Appl Radiat Isot (2012) 0.77
Evaluation of ketone-oxime method for developing therapeutic on-demand cleavable immunoconjugates. Bioconjug Chem (2008) 0.75
Design, synthesis, screening, and decoding of encoded one-bead one-compound peptidomimetic and small molecule combinatorial libraries. Methods Enzymol (2003) 0.75